Precision Medicine for Acute Respiratory Distress Syndrome (ARDS)

Dear Colleagues,

Acute respiratory distress syndrome (ARDS) is the most severe form of respiratory failure, significantly affecting the morbidity and mortality of critical care patients. ARDS is caused by various lung-injuring factors, leading to seemingly similar clinical manifestations requiring uniform management. However, the disease course and outcomes usually significantly differ in terms of the type of injury, intensity, and time of action of the factor. Differences can also be found between patients suffering from the same injury. An example is high (H) versus low (L) phenotype COVID-19-related ARDS, as described by Gattinoni. Phenotypic divisions of ARDS related to extrapulmonary and pulmonary causes can be considered some of the most clinically relevant. ARDS is based on two principal pathways leading to lung injury and, among other issues, encompasses different responses to therapeutic interventions. Phenotypes of ARDS are nowadays one of the leading ARDS-related topics; recently, even revoking the term ARDS was proposed.

In this Special Issue, we welcome authors to submit papers concerning various injury-specific types of ARDS, focusing on pathophysiologic and phenotypic differences and the relationship with possible future changes in diagnostic and treatment approaches.

Dr. Jan Máca
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.