Current Trends and Future Challenges in Assisted Reproduction

Dear Colleagues,

Infertility affects around 10–15% of couples worldwide, with a constantly growing trend in Western countries. Over the last decades, reproductive medicine has undergone a dramatic increase in several clinical and technological upgrades based on translational research discoveries.

In the past, the primary aim of assisted reproduction was to achieve pregnancy at any cost with the existing strategies. Contrastingly, at present, and particularly for the future studies, the objective of infertility care is to increase the chance of cumulative live birth rates for each couple, to individualized treatments based on the needs and characteristics of patients. In fact, the exponential contribution provided by multidisciplinary teams to develop new drugs, minimally invasive diagnostic and therapeutic tools, and advanced technologies has opened new opportunities to offer more effective and efficient approaches for infertility treatment.

In view of the presentation of current trends and future challenges in assisted reproduction, the aim of this Special Issue is to gather different and innovative perspectives for the treatment of human infertility, including both clinical and laboratory aspects. This includes the application of new protocols for ovarian stimulation, gamete and embryo culture and cryopreservation, embryo assessment via cutting-edge technologies such as time-lapse microscopy and artificial intelligence, as well as new and non-invasive applications of preimplantation genetic testing.

In this Special Issue, we would like to invite original clinical and basic research articles, meta-analyses and systematic reviews, aiming to update evidence on the future of assisted reproduction that embraces gynecological, andrological and embryological interests.

Dr. Stefano Canosa
Guest Editor

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