OMICS Revolution for Precision Medicine

Dear Colleagues,

A great challenge regarding research data in healthcare, bioinformatics, and precision medicine is the extraction of insightful, actionable knowledge from the streams of omics data related to patients that can be translated into effective therapies tailored to the molecular characteristics of the actual, biological state of an individual. In the context of host-related, genetic background vulnerabilities, or dysregulation of commensal microbiome promoting pathogenic infections, the role of comorbidities may now be examined through the manifold exploitation of diverse sequencing technologies.

Advances in “omics” technologies (e.g., genome, transcriptome, proteome, epigenome, metabolome) and their correlation with the clinical phenotypes of the individual patient are enabling medicine to move from a “one-size-fits-all” approach toward a “personalized” model, helping to clarify the molecular mechanisms underlying human disease and to provide both potential biomarkers and pharmacological targets for a more detailed patient stratification and personalized treatments. In this Special Issue, the most significant contributions of omics technologies, highlighting how these approaches are revealing diagnostic, prognostic, and therapeutic targets for future personalized interventions, are warmly welcome.

We especially encourage the submission of interdisciplinary works and multi-country collaborative research. We welcome the submission of original research papers using different study designs and critical and relevant reviews, including systematic reviews and meta-analyses, methodological papers, and manuscripts that emphasize theoretical content.

Prof. Dr. Salvatore Scacco
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.