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Journal of Functional Biomaterials publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Biomedical Applications of Hydrogels: Current Status and Advances

edited by Miriam Di Martino and

Simona Concilio

submission deadline 30 Sep 2026 | Viewed by 220 | Submission Open

Keywords: hydrogels; injectable hydrogels; stimuli-responsive hydrogels; drug delivery; gene delivery; wound healing; tissue engineering; regenerative medicine; 3D bioprinting; biosensing

(This special issue belongs to the Section Biomaterials and Devices for Healthcare Applications)

Engineered Living Materials for Biomedical Application

edited by

Xuebin Yang

Suitu Wang

and Yoo Jin Lee

submission deadline 30 Sep 2026 | Viewed by 219 | Submission Open

Keywords: engineered living materials; synthetic biology; biomanufacturing; regenerative medicine; drug delivery; smart biomaterials; biosensing

(This special issue belongs to the Section Biomaterials and Devices for Healthcare Applications)

Advanced Nanobiomaterials for Integrated Imaging, Therapy, and Diagnosis

edited by

Tejaswini Appidi

submission deadline 30 Sep 2026 | Viewed by 199 | Submission Open

Keywords: nanomedicine; imaging; therapy; diagnosis; multifunctional nanomaterials; theranostics

(This special issue belongs to the Section Biomaterials for Tissue Engineering and Regenerative Medicine)

Active Biomaterials as Regulators of Cell Behavior in Dynamic Microenvironments: Applications in Cancer and Regenerative Medicine

edited by Andrea Jennifer Vernengo

submission deadline 30 Sep 2026 | Viewed by 183 | Submission Open

Keywords: active biomaterials; dynamic microenvironments; cell behavior; cancer therapy; regenerative medicine; immune modulation; inflammation regulation

(This special issue belongs to the Section Biomaterials and Devices for Healthcare Applications)

Next-Generation Biofunctional Materials for Oral Rehabilitation and Maxillofacial Reconstruction: From Advanced Manufacturing to Smart Therapeutics

edited by

Pradeep Singh

Deepal Haresh Ajmera

and

Urszula Piotrowska

submission deadline 30 Sep 2026 | Viewed by 182 | Submission Open

Keywords: biofunctional materials; oral rehabilitation; maxillofacial reconstruction; advanced manufacturing; 3D bioprinting; smart therapeutics; stimuli responsive biomaterials

(This special issue belongs to the Section Dental Biomaterials)

Nanotechnology and Biomaterials in Targeted Gene Delivery and Cancer Therapy

edited by

Farbod Tabesh

and Suresh Thangudu

submission deadline 30 Sep 2026 | Viewed by 139 | Submission Open

Keywords: targeted gene delivery; nanocarrier systems; biomaterials engineering; CRISPR/cas gene editing; non-viral vectors; cancer nanomedicine; tumor microenvironment-responsive systems

(This special issue belongs to the Section Biomaterials for Cancer Therapies)

Next-Generation Biomaterials for Infection Control and Tissue Regeneration

edited by Wenshao Li, Ngoc Huu Nguyen and

Vi Khanh Truong

submission deadline 30 Sep 2026 | Viewed by 109 | Submission Open

Keywords: multifunctional biomaterials; stimuli-responsive systems/hydrogels; surface engineering and coatings; drug and gene delivery; tissue engineering and regenerative medicine; immunoengineering/immunomodulation; antimicrobial and antibiofilm; theranostics and biosensing; biofabrication/3D printing; biomaterials for cancer immunotherapy

(This special issue belongs to the Section Biomaterials for Tissue Engineering and Regenerative Medicine)

Role of Dental Biomaterials in Promoting Oral Health (2nd Edition)

edited by

Regina Maria Puppin-Rontani

submission deadline 30 Sep 2026 | Viewed by 95 | Submission Open

Keywords: novel biomaterials; clinical applications; biomechanical considerations; emerging technologies

(This special issue belongs to the Section Dental Biomaterials)

Development of Polymer-Based Nanomaterials for Cancer Therapy

edited by Sudhakar Godeshala

submission deadline 30 Sep 2026 | Viewed by 70 | Submission Open

Keywords: polymeric nanoparticles; targeted drug delivery; cancer nanomedicine; stimuli-responsive nanocarriers; combination therapy; biocompatibility

(This special issue belongs to the Section Biomaterials for Cancer Therapies)

15th Anniversary of JFB—Advanced Biomaterials for Periodontal Regeneration

edited by

Kerstin Gritsch

and

Thibault Canceill

submission deadline 10 Oct 2026 | Viewed by 567 | Submission Open

Keywords: periodontal regeneration; tissue engineering; biomaterials; scaffolds; hydrogels; bioactive molecules

(This special issue belongs to the Section Dental Biomaterials)

Biomaterials and Bioengineering in Dentistry (2nd Edition)

edited by

and

submission deadline 20 Oct 2026 | 2 articles | Viewed by 5447 | Submission Open

Keywords: dental materials; bioengineering; tissue engineering; biomaterials; stem cells; biomimetic; tissue regeneration; dental implants; bone grafts

(This special issue belongs to the Section Dental Biomaterials)

State of the Art in Biomaterials for Drug Delivery (2nd Edition)

edited by

Chengzhen Liu

submission deadline 20 Oct 2026 | Viewed by 343 | Submission Open

Keywords: biomaterials; natural materials; property of materials; drug delivery; controlled release

(This special issue belongs to the Section Biomaterials for Drug Delivery)

Functional Biomaterials for Skin Wound Healing

edited by

Suneel Kumar

submission deadline 24 Oct 2026 | 1 articles | Viewed by 13571 | Submission Open

Keywords: biomaterials; nanoparticles; spinal cord injury; traumatic brain injury; pressure ulcer; wound healing; diabetes; burn injury

(This special issue belongs to the Section Biomaterials for Tissue Engineering and Regenerative Medicine)

Advanced Metallic Biomaterials: Characterization, Optimization and Biomedical Applications

edited by

Cristina Jimenez-Marcos

and

Julia Claudia Mirza-Rosca

submission deadline 30 Oct 2026 | Viewed by 58 | Submission Open

Keywords: materials characterization; surface engineering; nanomaterials; metallic materials; biomedical applications; thin films; high entropy alloys; additive manufacturing

(This special issue belongs to the Section Biomaterials and Devices for Healthcare Applications)

Nanomaterials for Drug Targeting and Drug Delivery (2nd Edition)

edited by Chong Qiu

submission deadline 31 Oct 2026 | 3 articles | Viewed by 9227 | Submission Open

Keywords: nanomedicine; nanocarrier; drug delivery; target delivery; controlled release; biomaterials; nanozymes; extracellular vesicles

(This special issue belongs to the Section Biomaterials for Drug Delivery)

Biomaterials for Periodontal and Peri-Implant Regeneration

edited by

Mario Taba, Jr.

Adrian Kasaj

and

Chan Ho Park

submission deadline 31 Oct 2026 | 2 articles | Viewed by 3823 | Submission Open

Keywords: bone; periodontal; regeneration; periodontitis; peri-implantitis; biomaterial; scaffold

(This special issue belongs to the Section Dental Biomaterials)

Functional Nanomaterials for Gene Therapy

edited by

Rohit Sharma

and Pilar Blancafort

submission deadline 31 Oct 2026 | 1 articles | Viewed by 2218 | Submission Open

Keywords: functional nanomaterials; gene therapy; lipid nanoparticles (LNPs); nucleic acid delivery; CRISPR/Cas gene editing; biocompatibility and toxicity; targeted drug delivery

(This special issue belongs to the Section Biomaterials for Cancer Therapies)

Functional Scaffolds for Hard Tissue Engineering and Surgery

edited by

Ryszard Uklejewski

Mariusz Winiecki

and

Mikołaj Dąbrowski

submission deadline 31 Oct 2026 | 1 articles | Viewed by 2183 | Submission Open

Keywords: functional scaffolds; osteoconductive scaffolds; osteoinductive scaffolds; porous scaffolds; 3D-printed scaffolds; drug delivery scaffolds; hard tissue engineering scaffolds; hard tissue surgery; osteochondral repair; bone regeneration

(This special issue belongs to the Section Biomaterials for Tissue Engineering and Regenerative Medicine)

Innovative Approaches to Antimicrobial and Antiviral Functionalization of Textile Materials

edited by

Olivija Plohl

and

Lidija Fras Zemljič

submission deadline 31 Oct 2026 | 1 articles | Viewed by 1521 | Submission Open

Keywords: textile materials; antiviral and antimicrobial surfaces; bioactivity; personal protective equipment; hybrid multifunctional systems; smart textile; self-disinfecting surfaces; functionalization

(This special issue belongs to the Section Antibacterial Biomaterials)

Nanoparticles and Hydrogels for Drug Delivery Systems: Design and Synthesis

edited by

Samira Malekmohammadi

and

Rashid Jamshidi

submission deadline 31 Oct 2026 | 1 articles | Viewed by 1019 | Submission Open

Keywords: nanoparticles; hydrogel; drug delivery; design and synthesis; ultrasound drug delivery; microgels

(This special issue belongs to the Section Biomaterials for Drug Delivery)

State of the Art: Biomaterials in Bone Implant and Regeneration (2nd Edition)

edited by

Maria Sartori

and

Melania Maglio

submission deadline 31 Oct 2026 | 1 articles | Viewed by 647 | Submission Open

Keywords: biomaterials; implants; bone tissue and regeneration; preclinical and clinical studies

(This special issue belongs to the Section Bone Biomaterials)

Functional Biomaterials for Skin Reconstruction and Wound Healing

edited by

Stefanos Kikionis

and

Aikaterini Koutsaviti

submission deadline 31 Oct 2026 | Viewed by 581 | Submission Open

Keywords: biomaterials; biopolymers; natural polymers; skin injury; wound healing; wound dressings; tissue engineering; drug delivery; cell scaffolds; regenarative medicine

(This special issue belongs to the Section Biomaterials for Tissue Engineering and Regenerative Medicine)

Biomaterials Applied in Dental Sciences (2nd Edition)

edited by

Gustavo Fernandes

submission deadline 31 Oct 2026 | 1 articles | Viewed by 514 | Submission Open

Keywords: biomaterials; tissue engineering; tissue regeneration; scaffolds; periodontics; implant dentistry; biocompatibility

(This special issue belongs to the Section Dental Biomaterials)

Application of Nanomaterials in Drug Delivery and Drug Release

edited by Diana Iulia Savu

submission deadline 31 Oct 2026 | Viewed by 327 | Submission Open

Keywords: nanomaterials; drug delivery; drug release; nanoparticles; targeted therapy; controlled release; nanocarriers; nanomedicine

(This special issue belongs to the Section Biomaterials for Drug Delivery)

Innovative Surface Engineering and Bio-Manufacturing for Advanced Biomaterials

edited by

Mohammad Uddin

submission deadline 31 Oct 2026 | Viewed by 238 | Submission Open

Keywords: surface engineering; bio-manufacturing; biomaterials; medical implants; advanced alloys; coatings; biocompatibility

(This special issue belongs to the Section Synthesis of Biomaterials via Advanced Technologies)

Recent Advances in Gels for Tissue Engineering

edited by

Wildan Mubarok

and

Yujiang Fan

submission deadline 31 Oct 2026 | Viewed by 217 | Submission Open

Keywords: biomaterials; cell-instructive biomaterials; biofabrication; 3D bioprinting; mechanotransduction; stem cells differentiation; surface engineering; living materials

(This special issue belongs to the Section Biomaterials for Tissue Engineering and Regenerative Medicine)

Engineering Regeneration: Biomaterials, Biological Responses, and Translational Strategies

edited by

Young K. Kim

submission deadline 31 Oct 2026 | Viewed by 212 | Submission Open

Keywords: biomaterials; regenerative strategies; biological integration; translational application; tissue regeneration; bioactive interfaces; clinical decision-making

(This special issue belongs to the Section Biomaterials for Tissue Engineering and Regenerative Medicine)

Digital Technologies and Materials in Restorative Dentistry

edited by

Codruța Eliza Ille

and Do-Gyoon Kim

submission deadline 31 Oct 2026 | Viewed by 211 | Submission Open

Keywords: dental biomaterials; CAD/CAM technology; intraoral scanning; dental adhesion/smart adhesives; minimally invasive prosthodontics

(This special issue belongs to the Section Dental Biomaterials)

Current and Future Development Trends of Materials and Advanced Technologies Used in Endodontics

edited by Lucas Peixoto de Araújo, Ana Cristina Padilha Janini, Juliana Silva Ribeiro de Andrade and Mateus de Azevedo Kinalski

submission deadline 31 Oct 2026 | Viewed by 181 | Submission Open

Keywords: endodontic materials; endodontic files; instrumentation systems; endodontic sealers; repair cements; irrigation; laser-assisted endodontics; multisonic irrigation; ultrasonic activation; intracanal medicaments; vital pulp therapy; regenerative endodontics

(This special issue belongs to the Section Dental Biomaterials)

Biomaterials and In Vitro Development of Diseased Human Skin Models

edited by

Álvaro Sierra-Sánchez

submission deadline 31 Oct 2026 | Viewed by 93 | Submission Open

Keywords: biomaterial-based strategies; dermatological preclinical research; diseased models; in vitro models; skin; tissue engineering

(This special issue belongs to the Section Biomaterials and Devices for Healthcare Applications)

Advanced Biomaterials for Oral Medicine

edited by

Rosana Gomes Costa

and

Marta Relvas

submission deadline 31 Oct 2026 | Viewed by 90 | Submission Open

Keywords: tissue regeneration; regenerative dental medicine; bone regeneration; biocompatibility; tissue engineering

(This special issue belongs to the Section Dental Biomaterials)

Biomechanical Studies and Biomaterials in Dentistry (3rd Edition)

edited by

Hyun-Jung Kim

submission deadline 31 Oct 2026 | Viewed by 85 | Submission Open

Keywords: biomaterials; dental; restorative dentistry; regenerative dentistry; composite resins; nanotechnology in dentistry; biomechanical analysis; computational modeling

(This special issue belongs to the Section Dental Biomaterials)

Advances in Zirconia-Based Dental Materials

edited by Marko Jakovac and

Mark Žic

submission deadline 20 Nov 2026 | Viewed by 69 | Submission Open

Keywords: Fixed Prosthodontics; ; Dental Materials; ; Dental Ceramics; ; Zirconia; ; Digital Dentistry

(This special issue belongs to the Section Dental Biomaterials)

Advanced Materials for Clinical Endodontic Applications (3rd Edition)

edited by

Saulius Drukteinis

Sivaprakash Rajasekharan

and

Matthias Widbiller

submission deadline 30 Nov 2026 | 6 articles | Viewed by 10076 | Submission Open

Keywords: bioceramics; resin-based materials; nanomaterials; bioactive composites; endodontic sealers; irrigation solutions; intracanal medicaments; apexification; pulp capping; guided endodontics; regenerative endodontics; scaffolds; functional biomaterials; endodontic surgery; vital pulp therapy; pediatric endodontic biomaterials; dynamic navigation; antibacterial properties; biomaterial– tissue interactions

(This special issue belongs to the Section Dental Biomaterials)

Advances in Biomaterials and Regenerative Treatments for Oral and Maxillofacial Reconstruction

edited by Mihai Juncar,

Norina Consuela Forna

, Doriana Agop Forna and

Abel Emanuel Moca

submission deadline 30 Nov 2026 | 2 articles | Viewed by 1771 | Submission Open

Keywords: craniofacial reconstruction; regenerative biomaterials; dental reconstruction; dental tissue engineering; aesthetic and functional rehabilitation; bone and soft tissue regeneration; 3D printing and bioprinting in surgery; plastic and reconstructive surgery

(This special issue belongs to the Section Dental Biomaterials)

3D Printed and Biofabricated Bone Biomaterials: Enhancing Bone Repair and Regeneration

edited by

Elisa Batoni

Carmelo De Maria

and

Maria Chatzinikolaidou

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1206 | Submission Open

Keywords: biomaterials; bone scaffolds; 3D printing; additive manufacturing; bone tissue engineering; bone regeneration; biocompatibility

(This special issue belongs to the Section Bone Biomaterials)

3D-Printed Biomaterials: Development, Optimization, and Biomedical Applications

edited by Ali Entezari

submission deadline 30 Nov 2026 | 1 articles | Viewed by 910 | Submission Open

Keywords: 3D printing; additive manufacturing; biomedical implants; tissue engineering; bioprinting; computational modeling; personalized medicine

(This special issue belongs to the Section Biomaterials and Devices for Healthcare Applications)

Advancements in 3D Printing of Biomaterials

edited by

Mohammad J. Mirzaali

and

Yageng Li

submission deadline 30 Nov 2026 | Viewed by 299 | Submission Open

Keywords: 3D printing; biomaterials; tissue regeneration; scaffold; implants; medical devices; bioprinting

(This special issue belongs to the Section Synthesis of Biomaterials via Advanced Technologies)

Geometry-Driven Design of Biomaterial Scaffolds for Tissue Regeneration

edited by Stefan Lohfeld and Roland Manfred Klar

submission deadline 30 Nov 2026 | Viewed by 253 | Submission Open

Keywords: architected biomaterials; scaffold geometry; mechanobiology; tissue regeneration; additive manufacturing; osteoinduction; structure– function relationships

(This special issue belongs to the Section Biomaterials for Tissue Engineering and Regenerative Medicine)

Artificial Intelligence in Periodontology and Implantology

edited by

Yaniv Mayer

and Ofir Ginesin

submission deadline 30 Nov 2026 | Viewed by 78 | Submission Open

Keywords: artificial intelligence; periodontology; implantology

(This special issue belongs to the Section Dental Biomaterials)

Advances and Perspectives in Nanocarriers for Drug Delivery

edited by

Mantosh Kumar Satapathy

submission deadline 30 Nov 2026 | Viewed by 77 | Submission Open

Keywords: nanocarriers; drug delivery systems; functional biomaterials; targeted delivery; controlled release; nanomedicine; polymeric nanoparticles; liposomes; stimuli-responsive systems; pharmacokinetics; theranostics; translational nanotechnology

(This special issue belongs to the Section Biomaterials for Drug Delivery)

Smart Biomaterials for Oral Tissue Regeneration

edited by

Diana Marian

Ioana Elena Lile

Liana Todor

and Luminiţa Ligia Vaida

submission deadline 30 Nov 2026 | Viewed by 62 | Submission Open

Keywords: smart functional biomaterials; oral regeneration; bioactive biomaterials; nanostructured biomaterials; tissue engineering; implant osseointegration

(This special issue belongs to the Section Dental Biomaterials)

Material Innovations for Regenerative Medicine

edited by

Rogério Leone Buchaim

submission deadline 30 Nov 2026 | Viewed by 13 | Submission Open

Keywords: regenerative medicine; biomaterials; tissue engineering; smart materials; 3D bioprinting

(This special issue belongs to the Section Biomaterials for Tissue Engineering and Regenerative Medicine)

Advanced Biomaterials for Bone Tissue Engineering

edited by

Xueqin Gao

submission deadline 10 Dec 2026 | 10 articles | Viewed by 17941 | Submission Open

Keywords: biomaterials; bone defect; sustained-release biomaterials; biomaterials for drug delivery; mRNA therapeutics; exosomes and extracellular vesicles; biomaterials for fracture repair

(This special issue belongs to the Section Bone Biomaterials)

Advances in Biomaterials for Cancer Therapy

edited by

Tianjiao Zeng

and Huajian Chen

submission deadline 30 Dec 2026 | Viewed by 216 | Submission Open

Keywords: cancer therapy; drug delivery; biomechanics; tissue engineering; in vitro and in vivo model; tumor microenvironment; cancer drug resistance; biomedical devices; 3D culture

(This special issue belongs to the Section Biomaterials for Cancer Therapies)

Advanced Functional and Smart Biomaterials in Contemporary Prosthodontics

edited by

Diana Cerghizan

and

Ildiko Peter

submission deadline 30 Dec 2026 | Viewed by 154 | Submission Open

Keywords: smart biomaterials; prosthodontics; bioactive dental materials; nanotechnology; surface modification; CAD/CAM dentistry; additive manufacturing; dental implants

(This special issue belongs to the Section Dental Biomaterials)

Nature-Based Biomaterials for Biomedical Application

edited by

Vasileios Tsekouras

and

Sofia Mavrikou

submission deadline 30 Dec 2026 | Viewed by 60 | Submission Open

Keywords: nature-based biomaterials; biocompatibility; immune response; biomedical applications; tissue engineering; nanoparticles; natural polymers

(This special issue belongs to the Section Biomaterials and Devices for Healthcare Applications)

Functional Dental Materials for Orthodontics and Implants

edited by

Pavle Milanovic

Momir Stevanovic

and

Shinn-Jyh Ding

submission deadline 31 Dec 2026 | 5 articles | Viewed by 5549 | Submission Open

Keywords: dental materials; implants; bone regeneration; orthodontics; TADs; osseointegration; biocompatibility; biomehanics; surface modification

(This special issue belongs to the Section Dental Biomaterials)

Molecular Mechanisms and Biological Procedures of Biomaterials in Medical Applications (2nd Edition)

edited by

Yi Zhang

and Lu Xia

submission deadline 31 Dec 2026 | 1 articles | Viewed by 3428 | Submission Open

Keywords: biomaterials; bio– nano interaction; molecular mechanisms; biological procedures; bioinformatics; genetics; medical applications

(This special issue belongs to the Section Biomaterials and Devices for Healthcare Applications)

Advanced Biomaterials and Therapeutics for Bone Repair and Regeneration

edited by

Hemalatha Kanniyappan

and

Srirangam Ramanujam Vaibavi

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1544 | Submission Open

Keywords: bone regeneration; translational research; bioactive scaffolds; angiogenesis and osteogenesis; 3D bioprinting

(This special issue belongs to the Section Bone Biomaterials)

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