Functional Nanomaterials for Gene Therapy
A special issue of Journal of Functional Biomaterials (ISSN 2079-4983). This special issue belongs to the section "Biomaterials for Cancer Therapies".
Deadline for manuscript submissions: 31 October 2025 | Viewed by 700
Special Issue Editors
Interests: mRNA delivery; lipid nanoparticles; genome editing technologies; bioconjugation; cancer research
Special Issue Information
Dear Colleagues,
The field of functional nanomaterials for gene therapy is advancing fast, with the need for precise, efficient, and safe delivery vehicles for genetic cargo. Gene therapy holds great potential for the treatment of genetic disorders, cancers, and other complex diseases, but its clinical use is greatly reliant on the development of new nanomaterial-based delivery systems. Functional nanomaterials, including lipid nanoparticles, polymeric carriers, inorganic nanoparticles, and hybrid systems, are pioneering the breach of biological barriers, enhancing targeted delivery, and improving therapeutic efficacy. This Special Issue will highlight recent advances in functional nanomaterials designed for gene therapy applications. We welcome original research and review articles that cover, but are not limited to, the following topics:
- Design and development of nanomaterials for nucleic acid delivery.
- Lipid-based nanoparticles (LNPs) for gene therapy.
- Polymer-based and hybrid nanoparticle systems.
- Targeted and stimuli-responsive gene delivery platforms.
- CRISPR/Cas-based genome editing delivery systems.
- Biocompatibility, toxicity, and immune response of nanocarriers.
- Translational and clinical advancements in nanomaterial-based gene therapies.
This Special Issue will provide a comprehensive perspective on the current state of the field, bridging fundamental research and clinical applications. By integrating novel material designs with cutting-edge gene therapy strategies, we aim to facilitate the next generation of nanomedicine innovations.
We look forward to your valuable contributions to this exciting Special Issue.
Dr. Rohit Sharma
Dr. Pilar Blancafort
Guest Editors
Manuscript Submission Information
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Keywords
- functional nanomaterials
- gene therapy
- lipid nanoparticles (LNPs)
- nucleic acid delivery
- CRISPR/Cas gene editing
- biocompatibility and toxicity
- targeted drug delivery
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