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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Complications of Laparoscopic Cholecystectomy: Surgical Outcomes and Clinical Challenges
edited by
submission deadline 25 Aug 2026 | Submission Open
Keywords: laparoscopic cholecystectomy; bile duct injury; management of intraoperative injuries; surgical outcomes; postoperative infections
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Updates in Heart Failure: Innovations in Diagnosis, Therapy and Management
edited by Paolo Severino
submission deadline 28 Aug 2026 | Viewed by 31 | Submission Open
Keywords: heart failure; HFrEF therapy; HFpEF phenotyping; right ventricular dysfunction; renal congestion assessment; diuretic resistance; NT-proBNP dynamics; cardiac imaging; post-discharge management
(This special issue belongs to the Section Cardiology)
Clinical Management of Type 1 Diabetes: 2nd Edition
edited by Carmen Quirós
submission deadline 31 Aug 2026 | Viewed by 18 | Submission Open
Keywords: type 1 diabetes; continuous glucose monitoring; hybrid closed loop; hypoglycemia; physical activity; new onset type 1 diabetes; pre-stage 3 type 1 diabetes; smart insulin pens
(This special issue belongs to the Section Endocrinology & Metabolism)
Optimizing the Surgical Journey: From Abdominal Operation to Recovery
edited by and Carlo Bergamini
submission deadline 1 Sep 2026 | Viewed by 34 | Submission Open
Keywords: surgical complications; comanagement; comorbidities; elective surgical procedure; emergency surgery procedure; multidisciplinary approach; hospitalist
(This special issue belongs to the Section General Surgery)
Current Challenges in Clinical Dentistry: 3rd Edition
edited by and
submission deadline 15 Sep 2026 | Viewed by 48 | Submission Open
Keywords: artificial intelligence; clinical dentistry; cutting-edge device and technology; dental material; challenging hypothesis; preventive dentistry; sleep medicine; digital dentistry; smart dentistry; stomatognathic function
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Treatment and Clinical Management of Necrotizing Pancreatitis submission deadline 20 Sep 2026 | Viewed by 47 | Submission Open
Keywords: necrotizing pancreatitis; infected necrosis; step-up approach; necrosectomy; minimally invasive surgery; artificial intelligence; lumen-apposing metal stent; pancreatic necrosis
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Management in Dry Eye Disease: Current Strategies and Emerging Protocols
edited by Sunil Shah and Raquel Gil-Cazorla
submission deadline 20 Sep 2026 | Viewed by 34 | Submission Open
Keywords: dry eye disease; ocular surface; diagnostics; inflammation; biomarkers; emerging therapies
(This special issue belongs to the Section Ophthalmology)
Perinatal and Postnatal Mental Health: State of the Art
edited by Adriana Mihai
submission deadline 20 Sep 2026 | Viewed by 2 | Submission Open
Keywords: peripartum depression; post-partum depression; parental– infant well-being; early detection; perinatal mental health; postnatal mental health; psychotherapy interventions
(This special issue belongs to the Section Mental Health)
Advances in the Diagnosis and Management of Sarcoidosis
edited by , Pilar Brito-Zerón and Miriam Akasbi Montalvo
submission deadline 25 Sep 2026 | Viewed by 35 | Submission Open
Keywords: sarcoidosis; diagnosis; biomarkers; imaging; immunopathogenesis; biologic therapy; prognosis; interstitial lung disease
(This special issue belongs to the Section Immunology & Rheumatology)
Interplay of Motility, Microbiota, and Function: New Insights into GI Disorders, IBS, and SIBO
edited by Tsachi Tsadok Perets
submission deadline 30 Sep 2026 | Viewed by 23 | Submission Open
Keywords: gastrointestinal motility; irritable bowel syndrome (IBS); small intestinal bacterial overgrowth (SIBO); gut microbiota; functional gastrointestinal disorders
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Advances in Hepatology submission deadline 30 Sep 2026 | Viewed by 19 | Submission Open
Keywords: cirrhosis; portal hypertension; non-invasive tests; viral hepatitis; MASLD; HCC
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Fibromyalgia: Diagnostic Progress and Therapeutic Advances submission deadline 17 Nov 2026 | Viewed by 59 | Submission Open
Keywords: fibromyalgia; chronic pain; central sensitization; diagnostic biomarkers; advanced imaging; molecular markers; autonomic nervous system; cardiovascular regulation; emotional processing; cognitive dysfunction; fatigue; pain modulation; neuromodulation; tDCS
(This special issue belongs to the Section Clinical Neurology)
Dental Care: Oral and Systemic Disease Prevention: 2nd Edition
edited by
submission deadline 31 Dec 2026 | 1 articles | Viewed by 1560 | Submission Open
Keywords: oral health; oral diseases; oral manifestations; systemic diseases; oral care; dental prevention; dental caries; periodontal disease; oral medicine; dentistry; oral microbiome; salivary diagnostics; AI-assisted tools
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Aortic Diseases: Modern Strategies in Diagnosis, Management, and Prevention of Complications
edited by , Tilo Kölbel and José Ignacio F. Torrealba
submission deadline 20 Jul 2027 | Viewed by 134 | Submission Open
Keywords: aortic aneurysm; aortic dissection; genetic aortic disease; acute aortic syndromes; endovascular repair; complica-tions; outcomes
(This special issue belongs to the Section Vascular Medicine)
Insights into Urological Surgery: Evolving Practices, Trends, and Emerging Challenges submission deadline 30 Jul 2027 | Viewed by 39 | Submission Open
Keywords: urology; urological surgery; urological oncology; uro-technology; quality of life
(This special issue belongs to the Section Nephrology & Urology)
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