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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Acute Coronary Syndromes | Circulation Research submission deadline 20 Nov 2026 | 7 articles | Viewed by 5818 | Submission Open
Keywords: acute coronary syndromes; cardiovascular risk; individualized therapy; STEMI; risk factors
(This special issue belongs to the Section Cardiology)
New Insights in Paediatric Endocrinology
edited by
submission deadline 20 Nov 2026 | 5 articles | Viewed by 5477 | Submission Open
Keywords: endocrinology; pediatrics; hormones; therapy and treatment; adolescents; newborns
(This special issue belongs to the Section Clinical Pediatrics)
Oral and Maxillofacial Surgery: Current Progress and Future Directions submission deadline 20 Nov 2026 | 6 articles | Viewed by 5027 | Submission Open
Keywords: oral and maxillofacial surgery; digital planning; head and neck surgery; reconstructive surgery; implant–prosthetic rehabilitation; oral diseases; regenerative dentistry; AI
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Clinical Insights in Maternal–Fetal Medicine
edited by Moti Gulersen
submission deadline 20 Nov 2026 | 6 articles | Viewed by 4500 | Submission Open
Keywords: preterm birth; antenatal corticosteroids; preeclampsia; ultrasound; fetal growth; congenital anomalies; infection; maternal morbidity; diabetes; multiple gestation
(This special issue belongs to the Section Obstetrics & Gynecology)
Integrated Management of Long COVID: Fatigue, Emerging Evidence, and Therapeutic Innovations
edited by
submission deadline 20 Nov 2026 | 5 articles | Viewed by 3771 | Submission Open
Keywords: long COVID; post-COVID condition; fatigue; clinical management; rehabilitation; therapeutic innovation; integrative medicine; biomarkers
(This special issue belongs to the Section Infectious Diseases)
Clinical Aspects of Return to Sport After Injuries: 2nd Edition
edited by and
submission deadline 20 Nov 2026 | 3 articles | Viewed by 3480 | Submission Open
Keywords: musculoskeletal system; tissue overload; diagnostic methods; rehabilitation; treatment; injury prevention; return to sport; rehabilitation medicine; sports medicine
(This special issue belongs to the Section Sports Medicine)
The Latest Advancements in Solid Organ Transplantation
edited by Eviatar Nesher
submission deadline 20 Nov 2026 | 2 articles | Viewed by 3098 | Submission Open
Keywords: solid organ transplantation; robotic transplant surgery; living donor transplantation; indocyanine green fluorescence imaging; delayed graft function; mixed chimerism; tolerance induction; bone marrow transplantation; islet autotransplantation; total pancreatectomy; artificial intelligence; machine learning; kidney transplantation; liver transplantation; immunosuppression
(This special issue belongs to the Section General Surgery)
Current Understanding and Management of Asthma and Chronic Obstructive Pulmonary Disease
edited by Josuel Ora
submission deadline 20 Nov 2026 | 2 articles | Viewed by 3038 | Submission Open
Keywords: asthma; chronic obstructive pulmonary disease (COPD); personalized medicine; exacerbations; biomarkers; inhalation therapy; digital health; artificial intelligence; pulmonary rehabilitation; comorbidities
(This special issue belongs to the Section Respiratory Medicine)
Advances and Clinical Comparisons in Analgesia: Pharmacological, Non-Pharmacological, and Device-Based Approaches
edited by and
submission deadline 20 Nov 2026 | 2 articles | Viewed by 2521 | Submission Open
Keywords: acute pain; chronic pain; postoperative pain; non-pharmaceutical; pharmaceutical; analgesia; clinical
(This special issue belongs to the Section Anesthesiology)
Innovations in the Treatment for Depression and Anxiety—2nd Edition
edited by
submission deadline 20 Nov 2026 | 4 articles | Viewed by 2443 | Submission Open
Keywords: depression; anxiety; antidepressant; anxiolytic; psychopharmacotherapy; psychotherapy; brain stimulation; treatment; response; resistance
(This special issue belongs to the Section Mental Health)
Cardiometabolic Health and Cardiovascular Outcomes: Pathophysiology to Implementation submission deadline 20 Nov 2026 | 3 articles | Viewed by 2314 | Submission Open
Keywords: cardiometabolic disease; obesity; type 2 diabetes; cardiovascular risk; morbidity; mortality; prevention
(This special issue belongs to the Section Cardiovascular Medicine)
Colorectal Cancer: Screening, Diagnosis and Treatment
edited by and Sara De Dosso
submission deadline 20 Nov 2026 | 3 articles | Viewed by 2177 | Submission Open
Keywords: colorectal cancer; cancer screening; early diagnosis; multidisciplinary treatment; colorectal surgery; medical oncology; precision oncology; molecular biomarkers; real-world evidence; personalized medicine; health disparities; survivorship
(This special issue belongs to the Section Oncology)
Genitourinary Infections: Current Status and Emerging Challenges
edited by and George I. Kaparos
submission deadline 20 Nov 2026 | 4 articles | Viewed by 2147 | Submission Open
Keywords: genital tract infections; sexually transmitted infections; vaginal infections; urinary tract infections; recurrent infections; diagnostic challenges; antimicrobial resistance
(This special issue belongs to the Section Infectious Diseases)
Clinical Research in Vascular Access Devices
edited by
submission deadline 20 Nov 2026 | 2 articles | Viewed by 2067 | Submission Open
Keywords: short peripheral catheters; long peripheral catheters; midline; peripherally inserted central catheters (PICCs); femoral-inserted central catheters (FICCs); centrally inserted central catheters (CICCs); totally implantable venous access devices (TIVAD); catheter-related bloodstream infection (CRBSI); catheter-associated bloodstream infection (CABSI); central line-associated bloodstream infection (CLABSI); catheter-related thrombosis (CRT); fibroblastic sleeve; infiltration; extravasation
(This special issue belongs to the Section Vascular Medicine)
Electroencephalography: Advances in Clinical Applications submission deadline 20 Nov 2026 | 3 articles | Viewed by 2063 | Submission Open
Keywords: electroencephalography; clinical EEG; machine learning; deep learning; seizure detection; sleep EEG; brain–computer interface; neurodegenerative disease; consciousness assessment; automated diagnosis; multimodal neu-roimaging; human-AI benchmarking
(This special issue belongs to the Section Clinical Neurology)
Hematopoietic Stem Cell Transplantation: Current Research and New Perspectives
edited by
submission deadline 20 Nov 2026 | 2 articles | Viewed by 2005 | Submission Open
Keywords: allogenic transplantation; autologous transplantation; infection; GVHD; transplant related mortality; transplant complications; conditioning regimen; donor lymphocyte infusion; minimal residual disease; graft versus leukemia
(This special issue belongs to the Section Hematology)
Patient Blood Management Throughout the Hospital Pathway: Admission, Surgery, ICU, and Beyond
edited by and Kai Zacharowski
submission deadline 20 Nov 2026 | 1 articles | Viewed by 1965 | Submission Open
Keywords: anemia; blood health; blood loss; blood transfusion; coagulopathy; critical care; hemostasis; laboratory diagnostics; patient blood management; perioperative care; point-of-care testing; transfusion medicine; thrombosis; trauma; viscoelastic testing
(This special issue belongs to the Section Intensive Care)
Periodontal Diseases: Latest Advances in Diagnosis and Therapeutic Strategies
edited by Francesco Saverio Martelli and Giada Marroncini
submission deadline 20 Nov 2026 | 1 articles | Viewed by 1787 | Submission Open
Keywords: periodontal diseases; precision dentistry; genetic susceptibility; oral microbiome; inflammatory biomarkers; personalized therapy; multidisciplinary approach; periodontal diagnostics; host response modulation
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Thromboembolic Disease and Antithrombotic Therapy: 2nd Edition
edited by Prahlad Ho
submission deadline 20 Nov 2026 | 2 articles | Viewed by 1750 | Submission Open
Keywords: thrombosis; pulmonary embolism; manticoagulation; DOAC (direct oral anticoagulants); DVT (deep vein throm-bosis); novel anticoagulants (factor XIa inhibitors); thrombin; fibrin generation; risk stratification; biomarkers; Vir-chow’s triad; post thrombotic syndrome
(This special issue belongs to the Section Hematology)
Cardiac MRI: Current Techniques and Future Directions
edited by
submission deadline 20 Nov 2026 | 1 articles | Viewed by 1744 | Submission Open
Keywords: cardiac magnetic resonance imaging; technology; sequences; applications; acute coronary syndrome; intravascular imaging; CT-scanner
(This special issue belongs to the Section Cardiology)
Acute Management and Surgical Strategies in Orthopedic Trauma
edited by Hyung Keun Song
submission deadline 20 Nov 2026 | 3 articles | Viewed by 1739 | Submission Open
Keywords: orthopedic trauma; acute care; trauma surgery; damage control orthopedics; early definitive fixation; surgical timing; polytrauma; pelvic fracture; acetabular fracture; perioperative management; complications; clinical outcomes; trauma systems
(This special issue belongs to the Section Orthopedics)
Digital Mental Health and Artificial Intelligence: Clinical Perspectives and Patient Safety
edited by
submission deadline 20 Nov 2026 | 1 articles | Viewed by 1737 | Submission Open
Keywords: mental health care; telepsychiatry; telepsychotherapy; patient safety; health care data; clinical practice; digital mental health interventions; artificial intelligence in psychiatry; digital trust human–robot interactions; social networks
(This special issue belongs to the Section Mental Health)
Challenges in Emergency Medicine
edited by and Gregor Prosen
submission deadline 20 Nov 2026 | 3 articles | Viewed by 1632 | Submission Open
Keywords: in-hospital and prehospital care; care of the critically ill; resuscitation and post-resuscitation management; point-of-care ultrasound; emergency surgical and procedural interventions; digitalization and emerging technolo-gies; emergency medicine
(This special issue belongs to the Section Emergency Medicine)
Alcohol-Associated Liver Disease: Diagnosis and Treatment of Acute and Chronic Conditions
edited by Halina Cichoz-Lach and
submission deadline 20 Nov 2026 | 1 articles | Viewed by 1372 | Submission Open
Keywords: alcohol-associated liver disease; alcohol-associated hepatitis; alcohol-associated liver cirrhosis; excessive alcohol intake; oxidative liver damage; gut–liver axis; organ-to-organ crosstalk
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Updates on Cardiac Arrhythmias submission deadline 20 Nov 2026 | 1 articles | Viewed by 1257 | Submission Open
Keywords: clinical electrophysiology; inherited arrhythmia syndromes; arrhythmias in structural heart disease; catheter ablation; device-based therapy
(This special issue belongs to the Section Cardiology)
Advancing Mechanical Ventilation in Critical Care: From Clinical Foundations to Personalized Strategies
edited by
submission deadline 20 Nov 2026 | 2 articles | Viewed by 1238 | Submission Open
Keywords: mechanical ventilation; acute respiratory distress syndrome (ARDS); lung-protective ventilation; patient–ventilator interaction; personalized (precision) critical care
(This special issue belongs to the Section Intensive Care)
IBD Surgery and Short Bowel Syndrome
edited by and Paola Caprino
submission deadline 20 Nov 2026 | 1 articles | Viewed by 1235 | Submission Open
Keywords: abdominal surgery; minimally invasive surgery; robotic surgery; complex abdominal surgery; intestinal failure; short bowel syndrome; perioperative management; surgical outcomes; multidisciplinary care; surgical treatment of inflammatory bowel disease (IBD)
(This special issue belongs to the Section General Surgery)
Clinical Diagnosis and Management of Neonatal Diseases—Second Edition
edited by and Ayala Gover
submission deadline 20 Nov 2026 | 2 articles | Viewed by 1227 | Submission Open
Keywords: newborn; preterm; neonatal intensive care; low birth weight; point-of-care ultrasound; neonatal monitoring
(This special issue belongs to the Section Clinical Pediatrics)
Clinical Advances in Drug Safety and Polypharmacy submission deadline 20 Nov 2026 | 2 articles | Viewed by 1221 | Submission Open
Keywords: polypharmacy; medication safety; adverse drug reactions; drug–drug interactions; pharmacovigilance; artificial intelligence in healthcare; precision medicine; deprescribing; pharmacoepidemiology
(This special issue belongs to the Section Pharmacology)
Aiming for Early Detection and Prevention of Pulmonary Diseases submission deadline 20 Nov 2026 | 1 articles | Viewed by 1108 | Submission Open
Keywords: early diagnosis; prevention strategies; respiratory diseases; artificial intelligence; asthma; chronic obstructive pulmonary disease (COPD); interstitial lung disease; sleep-disordered breathing
(This special issue belongs to the Section Respiratory Medicine)
Current Advances in Spinal Cord Stimulation Therapy
edited by Alessandro Dario
submission deadline 20 Nov 2026 | 2 articles | Viewed by 1073 | Submission Open
Keywords: spinal cord stimulation; epidural stimulation; transcutaneous spinal cord stimulation; spasticity; neuropathic pain; Parkinson’s disease; paraplegia; Persistent Spinal Pain Syndrome Type 1; Persistent Spinal Pain Syndrome Type 2; diabetic polyneuropathy; electrical waveforms
(This special issue belongs to the Section Clinical Neurology)
Towards an Improved Understanding of Alzheimer's and Related Dementias: Interdisciplinary and Clinical Progress submission deadline 20 Nov 2026 | 2 articles | Viewed by 1063 | Submission Open
Keywords: Alzheimer’s disease; related dementias; neurodegeneration; biomarkers; neuroimaging; early diagnosis; cognitive decline; clinical management; therapeutic interventions; psychosocial care; risk factors; dementia prevention
(This special issue belongs to the Section Clinical Neurology)
Advances in Thoracic Surgery: Minimally Invasive Techniques, Precision Lung Resection, and Emerging Technologies
edited by
submission deadline 20 Nov 2026 | 1 articles | Viewed by 1038 | Submission Open
Keywords: minimally invasive thoracic surgery; robotic-assisted thoracic surgery (RATS); video-assisted thoracic surgery (VATS); precision lung resection; lung cancer surgery; segmentectomy; 3D imaging and surgical planning; extra-corporeal lung support
(This special issue belongs to the Section General Surgery)
Challenges in the Diagnosis and Management of Chronic Respiratory Diseases submission deadline 20 Nov 2026 | 2 articles | Viewed by 1012 | Submission Open
Keywords: chronic respiratory diseases; long-term respiratory care; comorbidities; COPD; asthma; interstitial lung disease; pulmonary rehabilitation
(This special issue belongs to the Section Respiratory Medicine)
Clinical Advances in HPV-Related Disease submission deadline 20 Nov 2026 | 1 articles | Viewed by 997 | Submission Open
Keywords: gynecological cancers; HPV; HPV vaccine; cervical cancer; precancerous lesions diagnostics
(This special issue belongs to the Section Obstetrics & Gynecology)
Latest Advances and Prospects in Urogynecology and Pelvic Floor Surgery
edited by
submission deadline 20 Nov 2026 | 1 articles | Viewed by 906 | Submission Open
Keywords: urogynecology; pelvic floor disorders; pelvic organ prolapse; urinary incontinence; fecal incontinence; minimally invasive surgery; pelvic floor imaging; vaginal surgery; pelvic pain syndrome
(This special issue belongs to the Section Obstetrics & Gynecology)
Heart Valve Surgery: Challenges and Advances in Conventional Surgery and Transcatheter Valve Therapy
edited by
submission deadline 20 Nov 2026 | 1 articles | Viewed by 898 | Submission Open
Keywords: mitral valve surgery; aortic valve surgery; tricuspid valve surgery; ross procedure; david procedure; transcatheter valve therapy; homograft valve replacement; infective endocarditis surgery
(This special issue belongs to the Section Cardiology)
Clinical Updates on Oral Health and Dental Care
edited by Wojciech Niemczyk and Rafał Wiench
submission deadline 20 Nov 2026 | 1 articles | Viewed by 860 | Submission Open
Keywords: oral health management; dental care; oral inflammatory diseases; oral diseases; preventive dentistry; periodontitis; oral medicine; clinical dentistry; dental surgery; periodontology
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
New Concepts in Diagnostic and Surgical HPB Technology
edited by
submission deadline 20 Nov 2026 | 1 articles | Viewed by 830 | Submission Open
Keywords: HPB surgery; minimal invasive approach; imaging; artificial intelligence; robotic surgery
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Hypertrophic Cardiomyopathy: From the Researcher Bench to the Clinical Patient Bedside
edited by , and Dejana R. Popović
submission deadline 20 Nov 2026 | 1 articles | Viewed by 776 | Submission Open
Keywords: hypertrophic cardiomyopathy; advanced imaging techniques; echocardiographic; cardiac magnetic resonance; biomarkers; surgical and interventional procedures
(This special issue belongs to the Section Cardiology)
Obesity and the Airway: Disease Mechanisms, Associated Conditions, and Management
edited by
submission deadline 20 Nov 2026 | 1 articles | Viewed by 764 | Submission Open
Keywords: obesity; airway; inflammation; rhinosinusitis; cerebrospinal fluid leak; asthma; chronic obstructive pulmonary disease; sleep; obstructive sleep apnea; intubation; laryngopharyngeal reflux; laryngotracheal stenosis
(This special issue belongs to the Section Respiratory Medicine)
Prostate Cancer: Clinical Advances and Prognosis Now and in the Near Future
edited by Josip Španjol
submission deadline 20 Nov 2026 | 1 articles | Viewed by 759 | Submission Open
Keywords: prostate cancer; immunotherapy; clinical trials; personalized medicine; artificial intelligence; robotic surgery; radical prostatectomy; radiotherapy
(This special issue belongs to the Section Nephrology & Urology)
Psychological Safety: Bodily and Psychological Determinants in Clinical Settings
edited by
submission deadline 20 Nov 2026 | 1 articles | Viewed by 743 | Submission Open
Keywords: psychological safety; fear; psychological trauma; shame; dissociation; neuroception; trust; polyvagal theory
(This special issue belongs to the Section Mental Health)
Management Strategies for Traumatic Brain Injury in Neurocritical Care Unit
edited by Etrusca Brogi
submission deadline 20 Nov 2026 | 3 articles | Viewed by 731 | Submission Open
Keywords: traumatic brain injury; neurocritical care; intracranial pressure; cerebral perfusion; neuroprotection; TBI management; critical care strategies; outcome prediction; rehabilitation; monitoring
(This special issue belongs to the Section Clinical Neurology)
Endocarditis: Clinical Updates on Diagnosis, Treatment and Management
edited by
submission deadline 20 Nov 2026 | 1 articles | Viewed by 722 | Submission Open
Keywords: infective endocarditis; PET; SPECT; echocardiography; antimicrobial therapy; cardiac surgery; multimodality imaging
(This special issue belongs to the Section Cardiology)
Clinical Advancements in Radiology of Joint and Musculoskeletal Diseases
edited by
submission deadline 20 Nov 2026 | 1 articles | Viewed by 707 | Submission Open
Keywords: sports injuries; ligament injuries; ankle injury; prognostic imaging; individualized imaging; imaging algorithms; lower-extremity injury; clinical insights; knee injuries; groin and hip pain
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Diagnosis, Monitoring, and Treatment of Myocardial Infarction: 2nd Edition
edited by
submission deadline 20 Nov 2026 | 1 articles | Viewed by 681 | Submission Open
Keywords: myocardial infarction; diagnosis; monitoring; treatment; acute MI
(This special issue belongs to the Section Cardiovascular Medicine)
New Technological Treatments and Methods in Neurorehabilitation
edited by
submission deadline 20 Nov 2026 | 1 articles | Viewed by 642 | Submission Open
Keywords: neurorehabilitation; robotics; virtual reality; exoskeleton; humankinesiology physiotherapy; stroke; parkinson's disease; gait; physical rehabilitation; rehabilitation interventions
(This special issue belongs to the Section Clinical Neurology)
Hip Fracture and Surgery: Clinical Updates and Challenges: 2nd Edition
edited by
submission deadline 20 Nov 2026 | 1 articles | Viewed by 634 | Submission Open
Keywords: antiosteoporosis medication; fracture liaison service; osteosynthesis; total hip arthroplasty; hemiarthroplasty
(This special issue belongs to the Section Orthopedics)
Interventional Pulmonology: Advances and Future Directions—2nd Edition
edited by Martina Ferioli and Piero Candoli
submission deadline 20 Nov 2026 | 1 articles | Viewed by 620 | Submission Open
Keywords: interventional pulmonology; lung nodule; lung cancer; diagnosis; bronchoscopy; rigid bronchoscopy; airway stent; airway stenosis; mediastinal staging
(This special issue belongs to the Section Respiratory Medicine)
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