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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances and Innovations in Hand Surgery

edited by

David L. Colen

, Jason Wink and Anthony Archual

submission deadline 25 Jun 2026 | 2 articles | Viewed by 1268 | Submission Open

Keywords: hand surgery; peripheral nerve surgery; shared decision making; microsurgery; arthritis; compression neuropathy; carpal tunnel; cubital tunnel

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Joint Repair and Replacement: Current Challenges and Opportunities

edited by Bartosz Gonera and Kacper Ruzik

submission deadline 25 Jun 2026 | 1 articles | Viewed by 1033 | Submission Open

Keywords: orthopedic biomechanics; knee injuries; joint replacement; anterior cruciate ligament; arthroscopy; sports medicine; prosthetic implants

(This special issue belongs to the Section Orthopedics)

Advancing Neonatal Seizures and Epilepsy: New Perspectives and Interventions

edited by

Elena Pavlidis

and Gaetano Cantalupo

submission deadline 25 Jun 2026 | 1 articles | Viewed by 709 | Submission Open

Keywords: neonatal seizures; neonatal epilepsy; neonatal EEG; automated EEG analysis; neonatal brain monitoring; genetic; precision medicine; genetic epilepsies; genome; exome

(This special issue belongs to the Section Clinical Pediatrics)

Advanced Image-Enhanced Endoscopy and Colonoscopy

edited by

Giuseppinella Melita

Marcello F. Maida

and Simona Di Caro

submission deadline 25 Jun 2026 | Viewed by 186 | Submission Open

Keywords: gastrointestinal endoscopy; colorectal cancer; endoscopic screening; artificial intelligence; chromoendoscopy

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Myocardial Infarction: Clinical Management and Future Options

edited by

Kenichi Sakakura

submission deadline 25 Jun 2026 | Viewed by 181 | Submission Open

Keywords: myocardial infarction; percutaneous coronary intervention; optimal medical therapy; clinical outcomes; cardiogenic shock; mechanical cardiac support device

(This special issue belongs to the Section Cardiology)

IgA Nephropathy: Clinical Updates and Prospects

edited by

Meritxell Ibernon

submission deadline 25 Jun 2026 | Viewed by 166 | Submission Open

Keywords: pathogenesis of IgA nephropathy; novel therapies; role of complement system; risk factors for disease progression; proteomic approach; serologic biomarkers; histological classification

(This special issue belongs to the Section Nephrology & Urology)

Clinical Advances of Aesthetic Plastic Surgery and Aesthetic Medicine

edited by Valentina Pinto and Rosalba Russo

submission deadline 25 Jun 2026 | Viewed by 166 | Submission Open

Keywords: aesthetic plastic surgery; aesthetic medicine; emerging technologies and devices in aesthetics; regenerative medicine and surgery; vulvovaginal surgery; complications in aesthetic medicine

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Multidisciplinary Care in Severe Traumatic Brain Injury Across the Continuum of Care: Acute, Rehabilitative, and Chronic Management

edited by Ryan Martin, Davin Quinn and Nicholas Race

submission deadline 25 Jun 2026 | Viewed by 117 | Submission Open

Keywords: severe traumatic brain injury; multidisciplinary; rehabilitation; advance practice providers; ancillary health; therapy; neuropsychology; nutrition

(This special issue belongs to the Section Brain Injury)

Cardiometabolic Disease and Atherosclerosis: Epidemiology, Prevention, Diagnosis, and Clinical Treatment—2nd Edition

edited by

Evangelos Oikonomou

and Konstantinos Mourouzis

submission deadline 25 Jun 2026 | Viewed by 116 | Submission Open

Keywords: atherosclerosis; obesity; cardiometabolic disease; prevention; diabetes mellitus; endothelium; arteriosclerosis; coronary artery disease

(This special issue belongs to the Section Cardiology)

Geriatric Cardiology: Clinical Advances and Comprehensive Management

edited by

Iris Parrini

submission deadline 25 Jun 2026 | Viewed by 110 | Submission Open

Keywords: geriatric assessment; management of cardiovascular disease; cardiovascular health; geriatric cardiology; frailty evaluation and management

(This special issue belongs to the Section Geriatric Medicine)

Recent Clinical Advances in Cardiac Rehabilitation: 2nd Edition

edited by

Tomasz Rechciński

submission deadline 25 Jun 2026 | Viewed by 107 | Submission Open

Keywords: cardiac rehabilitation; kinesiotherapy; psychological support; lifestyle modifications; myocardial infarction; heart failure

(This special issue belongs to the Section Cardiology)

Diet and Nutritional Aspects in Cardiovascular-Kidney-Metabolic Diseases (CKM)

edited by Krishnaswami Vijayaraghavan

submission deadline 25 Jun 2026 | Viewed by 105 | Submission Open

Keywords: cardiovascular-kidney-metabolic diseases (CKM); obesity; diabetes and metabolic syndrome; dietary factors; nutritional aspects; food policy and food security; chronic kidney disease; heart disease; technology

(This special issue belongs to the Section Clinical Nutrition & Dietetics)

Advances in Minimally Invasive and Endoscopic Neurosurgery

edited by Shunsuke Shibao

submission deadline 25 Jun 2026 | Viewed by 97 | Submission Open

Keywords: minimally invasive; endoscopic; keyhole; endonasal; transorbital; skull base; complications; surgical outcomes; technical innovations; robotic neurosurgery

(This special issue belongs to the Section Clinical Neurology)

Oral Health and Systemic Diseases: Clinical Insights

edited by

Fabio Piras

submission deadline 25 Jun 2026 | Viewed by 89 | Submission Open

Keywords: oral health; endodontics; orthodontic; periodontal disease; dental caries

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Surgical Innovations in Pediatric Orthopedics

edited by

Hoon Park

submission deadline 25 Jun 2026 | Viewed by 78 | Submission Open

Keywords: pediatric orthopedics; surgical innovation; growth modulation; absorbable implant; 3D printing

(This special issue belongs to the Section Orthopedics)

Bariatric Surgery: Current Status and Emerging Clinical Trends

edited by Collin E. M. Brathwaite

submission deadline 25 Jun 2026 | Viewed by 76 | Submission Open

Keywords: bariatric surgery; metabolic surgery; obesity; GLP-1 receptor agonists; robotic surgery; revisional surgery; weight regain; metabolic mechanisms; enhanced recovery; surgical innovation

(This special issue belongs to the Section General Surgery)

Upper Airway Management in Obstructive Sleep Apnea: Latest Advances and Future Perspectives

edited by Shintaro Chiba

submission deadline 25 Jun 2026 | Viewed by 69 | Submission Open

Keywords: obstructive sleep apnea (OSA); sleep surgery; upper airway stimulation (UAS); upper airway physiology

(This special issue belongs to the Section Respiratory Medicine)

Clinical Management of Traumatic Brain Injury

edited by Adam James Wells and Peter Hutchinson

submission deadline 25 Jun 2026 | Viewed by 67 | Submission Open

Keywords: traumatic brain injury; clinical management TBI; neurocritical care; neuromonitoring; trauma neurosurgery; artificial intelligence

(This special issue belongs to the Section Clinical Neurology)

Myopic Optic Neuropathy (MON) and Glaucomatous Optic Neuropathy (GON): Current Concepts and Clinical Implications

edited by

Etsuo Chihara

submission deadline 25 Jun 2026 | Viewed by 66 | Submission Open

Keywords: myopic optic neuropathy; glaucomatous optic neuropathy; tilting; axonal transport; lamina cribrosa

(This special issue belongs to the Section Ophthalmology)

Clinical Advancements in Laparoscopic Surgery for Gastrointestinal Diseases

edited by

Nikolaos Pararas

submission deadline 25 Jun 2026 | Viewed by 66 | Submission Open

Keywords: laparoscopic surgery; minimally invasive surgery; gastrointestinal diseases; colorectal cancer; gastric cancer; robotic surgery; fluorescence imaging; endoscopic-laparoscopic hybrid surgery; surgical oncology; future perspectives

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Diagnosis and Management of Corneal Diseases

edited by Nicola Cardascia

submission deadline 25 Jun 2026 | Viewed by 60 | Submission Open

Keywords: corneal surgery; lamellar keratoplasty; bioengineered corneal grafts; regenerative medicine; cell-based therapies; tissue-based therapies; Intraoperative imaging; corneal wound healing; lmmune modulation; graft survival; translational research; multimodal diagnostics; clinical outcomes; corneal transparency restoration; ophthalmic surgical innovation

(This special issue belongs to the Section Ophthalmology)

Technological Advancements and Clinical Innovations in Diagnostic and Interventional Radiology: 2nd Edition

edited by

Massimo Venturini

and

Federico Fontana

submission deadline 25 Jun 2026 | Viewed by 59 | Submission Open

Keywords: artificial intelligence; radiomics; image fusion; spectral computed tomography; functional magnetic resonance im-aging; CO2 angiography; balloon-occluded transcatheter arterial chemoembolization

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Human Immunodeficiency Virus: From Clinical Studies to Patient Outcomes

edited by Vítor Duque

submission deadline 25 Jun 2026 | Viewed by 58 | Submission Open

Keywords: HIV/AIDS; clinical trials; patient outcomes; clinical translational research

(This special issue belongs to the Section Infectious Diseases)

Cancer Prevention and Early Detection: Epidemiological Approaches and Public Health Strategies

edited by

Carmen Martos

and

Francesco Giusti

submission deadline 25 Jun 2026 | Viewed by 54 | Submission Open

Keywords: cancer prevention; cancer screening; risk factors; cancer treatment; health information systems; cancer registry; cancer inequalities

(This special issue belongs to the Section Epidemiology & Public Health)

Advances in Immunohematology: From Pathophysiology to Tailored Treatments

edited by

Giorgio Costagliola

submission deadline 25 Jun 2026 | Viewed by 51 | Submission Open

Keywords: autoimmune cytopenia; hemophagocytic lymphohistiocytosis; inborn errors of immunity; lymphoproliferative diseases; malignancy; monoclonal antibodies; secondary immunodeficiency; vaccination

(This special issue belongs to the Section Immunology & Rheumatology)

Integrating Artificial Intelligence and Contextual Factors in Emergency Care

edited by Ancor Sanz-García and

José Luis Martín-Conty

submission deadline 25 Jun 2026 | Viewed by 48 | Submission Open

Keywords: emergency care; artificial intelligence; early warning systems; data-driven healthcare; predictive analytics

(This special issue belongs to the Section Emergency Medicine)

Cystic Fibrosis: Management Strategies and Patient Outcomes

edited by Marta Rachel

submission deadline 25 Jun 2026 | Viewed by 45 | Submission Open

Keywords: cystic fibrosis; multidisciplinary care; personalized medicine; patient outcomes; telemedicine; pediatric pulmonology; CFTR modulators; chronic disease management

(This special issue belongs to the Section Respiratory Medicine)

Multifactorial Causation and Therapies of Myopia: 2nd Edition

edited by

César Villa Collar

Cristina Alvarez-Peregrina

and

David Piñero

submission deadline 26 Jun 2026 | 1 articles | Viewed by 1218 | Submission Open

Keywords: epidemiology; genetics; premyopia; simple and pathological myopia; orthokeratology; lenses for myopia control; blue light and red light; binocular vision and ocular optics; artificial intelligence

(This special issue belongs to the Section Ophthalmology)

Advances in General and Regional Anaesthesia

edited by Michał Jan Stasiowski,

Nikola Zmarzły

and

Beniamin Oskar Grabarek

submission deadline 26 Jun 2026 | 1 articles | Viewed by 78 | Submission Open

Keywords: general anaesthesia; regional anaesthesia; ropivacaine; bupivacaine; postoperative pain; postoperative nausea and vomiting; preventive analgesia; rescue opioid analgesia; total intravenous anaesthesia; inhalational anaesthesia

(This special issue belongs to the Section Anesthesiology)

Imaging and Molecular Biomarkers: The New Approach to Degenerative Retinal Diseases

edited by

Giulia Midena

and

Elisabetta Pilotto

submission deadline 28 Jun 2026 | 2 articles | Viewed by 1320 | Submission Open

Keywords: ophthalmology; degenerative retinal diseases; imaging biomarkers; multimodal imaging; OCT; OCT angiography; molecular biomarkers; precision medicine; translational ophthalmic research

(This special issue belongs to the Section Ophthalmology)

Youth Sports Injuries: From Prevalence to Prevention

edited by Swarup Mukherjee and

Gregory C. Bogdanis

submission deadline 30 Jun 2026 | 4 articles | Viewed by 12942 | Submission Open

Keywords: youth sports injuries; musculoskeletal injuries; injury prevention; sport safety; youth athletes

(This special issue belongs to the Section Sports Medicine)

The Atrial Fibrillation–Heart Failure Interconnection: Challenges and Innovations in Diagnosis and Treatment

edited by

Roberto De Ponti

and

Michele Golino

submission deadline 30 Jun 2026 | Viewed by 179 | Submission Open

Keywords: atrial fibrillation; catheter ablation; ventricular dysfunction; myocardial remodeling; diastolic dysfunction; biomarkers; anti-arrhythmia agents; risk assessment; artificial intelligence; telemedicine

(This special issue belongs to the Section Cardiovascular Medicine)

Ergonomics and Low Back Pain: Integrative Approaches to Prevention, Assessment and Management

edited by

Janan Abbas

and

Deborah Alperovitch

submission deadline 30 Jun 2026 | Viewed by 94 | Submission Open

Keywords: advanced in diagnostic methods; therapeutic innovations; multidisciplinary and personalized care models; prevention and rehabilitation; non-pharmacological strategies; ergonomics; biomechanics

(This special issue belongs to the Section Orthopedics)

New Clinical Insights into Acute Respiratory Failure

edited by

Christophe Guervilly

submission deadline 30 Jun 2026 | Viewed by 72 | Submission Open

Keywords: acute respiratory failure; pathophysiology; advances respiratory monitoring; respiratory support strategies; respiratory mechanics; mechanical ventilation; respiratory drive; patient-ventilator asynchrony

(This special issue belongs to the Section Intensive Care)

Integrating a One Health Approach into Antimicrobial Stewardship and Shared Care in Wound Management

edited by Joanna F. Blackburn

submission deadline 30 Jun 2026 | Viewed by 59 | Submission Open

Keywords: antimicrobial stewardship; antimicrobial resistance; one health; shared care; wound care; wound care management; chronic wound care; acute wound care; digital health; wound diagnostics; antimicrobials; antibiotics

(This special issue belongs to the Section Dermatology)

Clinical Advances in Aortic Disease and Revascularization: 2nd Edition

edited by Andrej Udelnow

submission deadline 30 Jun 2026 | Viewed by 50 | Submission Open

Keywords: aortic disease; aortic aneurysm; endovascular aortic repair; atherosclerosis; aortic dissections; overall survival; quality of life; intravascular ultrasound

(This special issue belongs to the Section Vascular Medicine)

Robotic-Assisted Hepato-Pancreato-Biliary (HPB) Surgery: Advances and Clinical Perspectives

edited by

Michele Tedeschi

and Riccardo Memeo

submission deadline 30 Jun 2026 | Viewed by 33 | Submission Open

Keywords: liver surgery; pancreatic surgery; HPB surgery; robotic surgery; robotic systems; advances in HPB surgery

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Advances in Anterior Cruciate Ligament Injury Treatment

edited by Goran Vrgoč

submission deadline 1 Jul 2026 | Viewed by 43 | Submission Open

Keywords: anterior cruciate ligament (ACL) injury; ACL reconstruction techniques; nonoperative ACL treatment; ACL graft; knee biomechanics; return-to-sport assessment; ACL rehabilitation; neuromuscular and proprioceptive training; athletic injuries; performance-enhancing substances; reinjury prevention; psychological readiness; ACL performance testing; osteoarthritis risk

(This special issue belongs to the Section Orthopedics)

Modern Challenges in Pediatric Endocrinology: From Growth Disorders to Metabolic Dysregulation

edited by Katarzyna A. Majewska and Piotr Fichna

submission deadline 2 Jul 2026 | Viewed by 101 | Submission Open

Keywords: growth hormone deficiency; growth hormone therapy; short stature; obesity; obesity complications; obesity treatment; insulin resistance; prediabetes; type 1 diabetes; type 2 diabetes; hypothyroidism; hyperthyroidism; autoimmune thyroiditis; puberty disorders

(This special issue belongs to the Section Clinical Pediatrics)

Clinical Management for Coronary Artery Disease and Revascularization

edited by Mohammad Reza Movahed

submission deadline 10 Jul 2026 | 3 articles | Viewed by 4911 | Submission Open

Keywords: coronary artery disease; coronary syndrome; stenting; revascularization; cardiovascular

(This special issue belongs to the Section Cardiovascular Medicine)

New Insights into Skin Tumors: From Pathogenesis to Therapy

edited by Loredana Ungureanu and Simona C. Şenilǎ

submission deadline 10 Jul 2026 | 3 articles | Viewed by 3105 | Submission Open

Keywords: skin tumors; pathogenesis; diagnosis; personalized medicine; therapeutic strategies; dermato-oncology

(This special issue belongs to the Section Dermatology)

Visualizing Cardiac Function: Advances in Modern Imaging Diagnostics

edited by Dafni Charisopoulou and

Michael Henein

submission deadline 10 Jul 2026 | 1 articles | Viewed by 352 | Submission Open

Keywords: cardiac imaging; echocardiography; coronary artery disease; valve disease; heart failure

(This special issue belongs to the Section Cardiology)

Gynecologic Cancers: Integrating Established Standards and Innovative Approaches

edited by Radu Vladareanu and Liviu Bilteanu

submission deadline 10 Jul 2026 | Viewed by 73 | Submission Open

Keywords: gynecological cancers; cervical cancer; ovarian cancer; endometrial cancer; vulvar and vaginal tumors; uterine sarcoma; fertility preservation; robotic surgery; image-guided radiotherapy (IGRT); brachytherapy; proton and FLASH radiotherapy; immunotherapy; radiomics; artificial intelligence; digital twin; multimodal treatment; survivorship and quality of life

(This special issue belongs to the Section Oncology)

Endoscopic Therapy in Gastroesophageal Reflux Disease (GERD): Current Evidence, Techniques, and Future Perspectives

edited by Pier Alberto Testoni

submission deadline 10 Jul 2026 | Viewed by 59 | Submission Open

Keywords: gastroenterology; gastroesophageal reflux disease; GERD; esophageal diseases; endoscopic therapy

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Emerging Biomarkers and Novel Diagnostic Tools in Respiratory Diseases: From Bench to Bedside

edited by

Silvano Dragonieri

and

Andras Bikov

submission deadline 10 Jul 2026 | Viewed by 56 | Submission Open

Keywords: respiratory diseases; biomarkers; non-invasive approaches; novel diagnostic tests; precision medicine; personalized therapy; disease phenotyping; diagnostic tools; functional biomarkers; imaging biomarkers; molecular biomarkers

(This special issue belongs to the Section Respiratory Medicine)

Open, Hybrid and Endovascular Repair of Visceral Artery Aneurysms: State of the Art and Clinical Perspectives

edited by

Andrea Xodo

, Francesco Squizzato and Vincenzo Vento

submission deadline 10 Jul 2026 | Viewed by 39 | Submission Open

Keywords: visceral artery aneurysms; endovascular treatment; open surgical repair; hybrid approach; covered stents; end-organ ischemia; long-term durability; patient selection

(This special issue belongs to the Section Vascular Medicine)

Personalized Medicine: Future Perspectives on Personalized Oral and Maxillofacial Surgery

edited by

Cosmin Ioan Faur

, Rareș Calin Roman and Mihaela Carmen Hedeşiu

submission deadline 15 Jul 2026 | 1 articles | Viewed by 915 | Submission Open

Keywords: head and neck surgery; head and neck oncology; head and neck reconstructions; personalized medicine; artificial intelligence; head and neck trauma; integrative medicine

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Updates on Epilepsy Researches

edited by

Guillermo Estivill-Torrús

submission deadline 15 Jul 2026 | Viewed by 153 | Submission Open

Keywords: epilepsy; autoimmune epilepsy; neural autoantibodies; seizure disorders; experimental epilepsy models; animal studies; neuronal excitability; immunotherapy; predictive scoring systems; epilepsy biomarkers

(This special issue belongs to the Section Clinical Neurology)

Total Hip Arthroplasty Today: Trends, Challenges, and Future Directions

edited by

Seung-Jae Lim

submission deadline 15 Jul 2026 | Viewed by 120 | Submission Open

Keywords: complex hip arthroplasty; surgical technique; innovative implant; new technology; robotic surgery; navigation surgery; artificial intelligence; complications; periprosthetic joint infection; periprosthetic fracture; dislocation

(This special issue belongs to the Section Orthopedics)

Aortic Dissection: Current Trends, Complexities, and Future Directions

edited by Aung Ye Oo

submission deadline 15 Jul 2026 | Viewed by 96 | Submission Open

Keywords: aortic dissection; aortic surgery; hybrid and endovascular repair; diagnostic delay; systems of care; patient safety; biomarkers and imaging; postoperative outcomes; multidisciplinary collaboration in aortic disease management

(This special issue belongs to the Section Cardiovascular Medicine)

Displaying special issue 1251-1300 on page 26 of 31.

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