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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Clinical Advances in Trauma and Orthopaedic Surgery

edited by Valerio Pace and Pierluigi Antinolfi

submission deadline 20 Jun 2026 | 3 articles | Viewed by 5326 | Submission Open

Keywords: orthopaedic surgery; hand/wrist surgery; tendon injury; ligament injury; artificial intelligence (AI); robotic surgery; orthopaedic injections; nerve injury

(This special issue belongs to the Section Orthopedics)

Evidence-Based Diagnosis and Clinical Management of Low Back Pain

edited by

William J. Hanney

and

Michael Masaracchio

submission deadline 20 Jun 2026 | 2 articles | Viewed by 5293 | Submission Open

Keywords: low back pain; classification systems; risk stratification; health services research; management strategies; timing and sequencing; prognosis; predictor; clinical decision making; primary care

(This special issue belongs to the Section Clinical Rehabilitation)

AI in Maternal Fetal Medicine and Perinatal Management

edited by Ariel Many

submission deadline 20 Jun 2026 | 2 articles | Viewed by 5230 | Submission Open

Keywords: maternal fetal medicine; high-risk pregnancy; perinatal management; artificial intelligence (AI) in obstetrics; fetal growth abnormalities; preterm labor prediction

(This special issue belongs to the Section Obstetrics & Gynecology)

Maternal–Fetal Medicine: Current Status, Challenges, and Future Directions

edited by Jessian Munoz

submission deadline 20 Jun 2026 | 4 articles | Viewed by 4380 | Submission Open

Keywords: maternal– fetal medicine; preterm delivery; preterm birth management; newborn; obstetrics; high-risk pregnancy; perinatal outcome; placenta accreta; fetal surgery

(This special issue belongs to the Section Obstetrics & Gynecology)

Advancements in Femtosecond Laser Applications

edited by Luca Schwarzenbacher, Eva Stifter and Philipp Roberts

submission deadline 20 Jun 2026 | 4 articles | Viewed by 4293 | Submission Open

Keywords: femtosecond laser; cataract surgery; DSAEK; DALK; femto-CAIRS; congenital cataract

(This special issue belongs to the Section Ophthalmology)

Advances in Clinical Approaches to Breast Cancer Diagnosis and Treatment

edited by

Lorenzo Scardina

submission deadline 20 Jun 2026 | 2 articles | Viewed by 4110 | Submission Open

Keywords: breast cancer; diagnosis; precision medicine; molecular profiling; targeted therapy; breast-conserving surgery; minimally invasive techniques; artificial intelligence; personalized medicine; radiation therapy

(This special issue belongs to the Section Oncology)

Ultrasound-Guided Biopsy of Gynecologic Tumors: Technique and Clinical Application

edited by

Athina A. Samara

and Alexandros Daponte

submission deadline 20 Jun 2026 | 1 articles | Viewed by 3400 | Submission Open

Keywords: ultrasound-guided biopsy; gynecologic tumors; ovarian cancer; biopsy technique; precision diagnosis; endometrial lesions

(This special issue belongs to the Section Obstetrics & Gynecology)

Updates on the Clinical Applications of Dental Restorative Materials

edited by

Vittorio Checchi

submission deadline 20 Jun 2026 | 1 articles | Viewed by 3296 | Submission Open

Keywords: restorative dentistry; restorations; adhesive dentistry; resin composites; ceramics; aesthetics; dental materials; direct restorations; indirect restorations; conservative dentistry; prosthetic dentistry; partial restorations; total restorations

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Antithrombotic Therapies for Acute Coronary Syndrome and Atrial Fibrillation

edited by

Mojca Božič Mijovski

submission deadline 20 Jun 2026 | 2 articles | Viewed by 3285 | Submission Open

Keywords: atrial fibrillation; acute coronary syndrome; antiplatelet agents; anticoagulants; thrombolysis; direct coagulation factor inhibitors; medical laboratory technology

(This special issue belongs to the Section Cardiology)

Innovations in the Clinical Management of Retinal Diseases: Emerging Therapies and Visual Rehabilitation

edited by

Francisco J. Povedano-Montero

submission deadline 20 Jun 2026 | 3 articles | Viewed by 2952 | Submission Open

Keywords: retinal diseases; macular degeneration; maculopathies; diabetic retinopathy; retinal vascular occlusions; retinitis pigmentosa

(This special issue belongs to the Section Ophthalmology)

Genitourinary Cancers: Clinical Advances and Practice Updates

edited by David Benjamin and Arash Rezazadeh Kalebasty

submission deadline 20 Jun 2026 | 3 articles | Viewed by 2846 | Submission Open

Keywords: rare tumors; genitourinary cancers; urachal cancer; penile cancer; testicular cancer; variant histology

(This special issue belongs to the Section Nephrology & Urology)

Advances in Diagnosis and Treatment of Urological Cancers

edited by Davide Campobasso,

Stefano Puliatti

and

Daniele Amparore

submission deadline 20 Jun 2026 | 2 articles | Viewed by 2604 | Submission Open

Keywords: prostate cancer; kidney cancer; urothelial carcinoma; testis cancer; mini-invasive surgery; precision surgery; target therapy; immunotherapy; nuclear medicine; artificial intelligence; augmented reality; biomarkers; prognostic factors and models; focal therapy; radiotherapy; imaging; genetics

(This special issue belongs to the Section Nephrology & Urology)

State-of-the-Art in Cardiac Surgery: Progress, Challenges and Opportunities

edited by Tomasz Plonek and Sleiman Sebastian Aboul-Hassan

submission deadline 20 Jun 2026 | 3 articles | Viewed by 2420 | Submission Open

Keywords: aorta ascendens; minimally invasive surgery; aortic arch surgery; off pump coronary surgery; arterial grafts

(This special issue belongs to the Section Cardiology)

Novel Aspects of Endocrine Care: From Patient-Centred Management of Endocrine Diseases to Guidelines Standards

edited by

Mara Carsote

and

Claudiu Nistor

submission deadline 20 Jun 2026 | 2 articles | Viewed by 2357 | Submission Open

Keywords: endocrine tumour; hormone; biomarker; neuroendocrine tumour; thyroidectomy; parathyroidectomy; bone; ad-renal gland; osteoporosis; pituitary gland; autoimmune; antibody; clinical study; computed tomography

(This special issue belongs to the Section Endocrinology & Metabolism)

New Insights in Maxillofacial Surgery

edited by

Izumi Asahina

submission deadline 20 Jun 2026 | 1 articles | Viewed by 2161 | Submission Open

Keywords: maxillofacial surgery; surgical techniques; imaging technologies; biomaterials; regenerative medicine

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Recent Advances in Transcatheter Aortic Valve Replacement: Second Edition

edited by

Anna Olasińska-Wiśniewska

and Maciej Dąbrowski

submission deadline 20 Jun 2026 | 2 articles | Viewed by 1914 | Submission Open

Keywords: aortic stenosis; transcatheter; bioprosthesis; TAVI; transcatheter aortic valve replacement

(This special issue belongs to the Section Cardiovascular Medicine)

Current Challenges and Perspectives in Liver Transplantation

edited by Bogdan Dorobanţu,

Umberto Cillo

and Waldo Concepcion

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1439 | Submission Open

Keywords: liver transplantation; liver surgery; liver cirrhosis; liver disease; alcoholic and non-alcoholic steatohepatitis; cholangiocarcinoma; hepatocellular carcinoma; auxiliary liver transplantation

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Current Perspectives and Innovations in Urogynecology

edited by Stavros Athanasiou

submission deadline 20 Jun 2026 | 2 articles | Viewed by 1254 | Submission Open

Keywords: urogynecology; pelvic organ prolapse; urinary incontinence; overactive bladder; pelvic floor surgery; reconstructive surgery; minimally invasive surgery; pelvic floor disorders; innovative surgical techniques; quality of life

(This special issue belongs to the Section Obstetrics & Gynecology)

Innovations in Psychosis and Schizophrenia: New Findings and Implications

edited by

Gabriele Nibbio

submission deadline 20 Jun 2026 | 2 articles | Viewed by 1226 | Submission Open

Keywords: schizophrenia; psychosis; psychopathology; neurobiology; assessment; pharmacological treatment; psychosocial interventions

(This special issue belongs to the Section Mental Health)

New Perspectives in Maternal–Fetal Medicine

edited by Catalina de Paco-Matallana

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1190 | Submission Open

Keywords: maternal– fetal medicine; prenatal diagnostics; fetal therapy; precision medicine; neonatal outcomes; maternal health

(This special issue belongs to the Section Obstetrics & Gynecology)

Cardiovascular Imaging: Diagnosis and Therapeutic Guidance in Clinical Practice

edited by

Stefano Figliozzi

submission deadline 20 Jun 2026 | 1 articles | Viewed by 955 | Submission Open

Keywords: cardiovascular magnetic resonance; cardiac imaging; T1 and T2 mapping; myocardial tissue characterization; late gadolinium enhancement; ischemic heart disease; cardiomyopathies; valvular heart disease; therapeutic guidance; precision medicine; mitral valve prolapse

(This special issue belongs to the Section Cardiology)

Therapies for Heart Failure: Clinical Updates and Perspectives

edited by Cristina Tudoran, Stela Iurciuc and Dragos Cozma

submission deadline 20 Jun 2026 | 1 articles | Viewed by 906 | Submission Open

Keywords: mechanisms of heart failure; new therapies for heart failure; chronic and acute heart failure; new approaches to managing heart failure patients; special populations; clinical outcome

(This special issue belongs to the Section Cardiology)

Clinical Advances in the Pharmacotherapy of Diabetes

edited by Jonathan Watanabe,

Joshua J. Neumiller

and

Cheyenne Frazier

submission deadline 20 Jun 2026 | 1 articles | Viewed by 834 | Submission Open

Keywords: diabetes; microvascular complications; macrovascular complications; diabetes technology; pharmacoepidemiology; care delivery; novel therapies

(This special issue belongs to the Section Pharmacology)

New Clinical Advances in Breast Reconstruction

edited by

Nobuyuki Mitsukawa

submission deadline 20 Jun 2026 | 1 articles | Viewed by 775 | Submission Open

Keywords: breast reconstruction; autologous (flap) reconstruction; implant-based reconstruction; microsurgery and perforator flaps; robotic surgery/endoscopic surgery; fat grafting (lipofilling); patient-reported outcomes; reconstructive surgical innovation

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Parkinson's Disease: Recent Advances in Diagnosis and Treatment

edited by

Mariachiara Sensi

and

Fabiana Colucci

submission deadline 20 Jun 2026 | 1 articles | Viewed by 656 | Submission Open

Keywords: Parkinson’ s disease; disease-modifying therapies; artificial intelligence; microbiome; alpha-synuclein; neuroimaging

(This special issue belongs to the Section Clinical Neurology)

Stroke in Patients with Atrial Fibrillation: Risk, Manifestation and Prevention

edited by

Iwona Gorczyca-Głowacka

submission deadline 20 Jun 2026 | 1 articles | Viewed by 573 | Submission Open

Keywords: anticoagulant treatment; atrial fibrillation; arrhythmia; personalized medicine; stroke

(This special issue belongs to the Section Cardiology)

The New Era of Urological Surgery: Technology-Enhanced Clinical Outcomes

edited by

Razvan-George Rahota

and

Guillaume Ploussard

submission deadline 20 Jun 2026 | Viewed by 569 | Submission Open

Keywords: urology; surgery; robotic surgery; artificial intelligence; urological cancer

(This special issue belongs to the Section Nephrology & Urology)

Novel Insights into the Use of Artificial Intelligence in Clinical Medicine

edited by Sharon C. Kiang and Roger T. Tomihama

submission deadline 20 Jun 2026 | 1 articles | Viewed by 482 | Submission Open

Keywords: artificial intelligence; disease predictive models; wearable technology; surgical innovation; molecular targeting; big data science; machine learning; deep learning

Neuroimmunological Disorders: Mechanisms and Therapies

edited by

Christos Bakirtzis

and

Marina Kleopatra Boziki

submission deadline 20 Jun 2026 | 1 articles | Viewed by 466 | Submission Open

Keywords: neuroinflammatory; multiple sclerosis; neuromyelitis optica spectrum disorders; mog associated disease; autoimmune/paraneoplastic encephalitis

(This special issue belongs to the Section Clinical Neurology)

Advanced Endoscopy and Imaging in Gastrointestinal Diseases

edited by

Iancu Dana Monica

and

Paul-Andrei Ștefan

submission deadline 20 Jun 2026 | 1 articles | Viewed by 417 | Submission Open

Keywords: advanced endoscopy; gastrointestinal imaging; minimally invasive therapy; early diagnosis; image-guided intervention; surgical planning; patient outcomes; gastrointestinal diseases

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Orthopedic Oncology Updates and Controversial Issues

edited by Yehuda Kollender and Ron Batash

submission deadline 20 Jun 2026 | Viewed by 409 | Submission Open

Keywords: soft tissue sarcoma; bone sarcoma; oligometastatic; atypical behavior tumor; cryosurgery; rare diseases; surgery; radiation therapy; immunotherapy; chemotherapy

(This special issue belongs to the Section Orthopedics)

New Advances in Oral and Facial Surgery: 2nd Edition

edited by

Olindo Massarelli

submission deadline 20 Jun 2026 | 1 articles | Viewed by 396 | Submission Open

Keywords: squamous cell carcinoma; oro-pharyngeal tumors; skin tumors; plastic and reconstructive surgery; facial plastic surgery; facial reanimation; facial nerve palsy; head and neck surgery; maxillofacial surgery; aesthetic surgery; orthognatic surgery; dental implant surgery

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Advances in Scoliosis and Spinal Disorders: Diagnosis and Management

edited by Tejas Subramanian

submission deadline 20 Jun 2026 | 1 articles | Viewed by 380 | Submission Open

Keywords: spine surgery; adult spinal deformity; frailty; sarcopenia; muscle health; postoperative recovery; patient-reported outcomes

(This special issue belongs to the Section Orthopedics)

Clinical Advances and Challenges in Liver Transplantation: 3rd Edition

edited by

Paola Aceto

submission deadline 20 Jun 2026 | 1 articles | Viewed by 334 | Submission Open

Keywords: liver transplantation (LT); elderly donors; steatotic livers; donors after circulatory death (DCD); hepatocellular carcinoma (HCC); perioperative management

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Advances in Cardiovascular Rehabilitation: The Central Role of Exercise in Prevention and Care

edited by Massimo Pistono

submission deadline 20 Jun 2026 | 2 articles | Viewed by 308 | Submission Open

Keywords: cardiac rehabilitation; secondary prevention; physical exercise; cardiovascular health; aerobic exercise; cardio-oncology rehabilitation

(This special issue belongs to the Section Cardiovascular Medicine)

Hospital-Acquired Infections: Insights, Prevention, and Control Strategies

edited by

Andrea Fabbri

submission deadline 20 Jun 2026 | Viewed by 224 | Submission Open

Keywords: healthcare-acquired infections; bloodstream infections; hospital‐acquired pneumonia; intestinal infections; clostridium difficile; surgical site infections; urinary tract infections; emergency department

(This special issue belongs to the Section Epidemiology & Public Health)

Pulmonary Critical Care: Integrating Bedside Physiology and Advanced Monitoring in the Management of Severe Respiratory Diseases

edited by

Gaetano Scaramuzzo

submission deadline 20 Jun 2026 | Viewed by 218 | Submission Open

Keywords: lung monitoring; ARDS; ARF; biomarkers; lung physiology; pneumonia; lung ultrasound; artificial intelligence; COPD; EIT

(This special issue belongs to the Section Respiratory Medicine)

The Treatment of BPO with Minimal Invasive Approach

edited by

Lukas Lusuardi

submission deadline 20 Jun 2026 | Viewed by 161 | Submission Open

Keywords: benign prostatic obstruction (BPO); prostatectomy; non-muscle invasive bladder cancer; muscle invasive bladder cancer; robotic surgery

(This special issue belongs to the Section Nephrology & Urology)

Oral and Maxillofacial Surgery: Clinical Progress, Challenges and Opportunities

edited by Janet Hayes Southerland and Leslie Robin Halpern

submission deadline 20 Jun 2026 | Viewed by 140 | Submission Open

Keywords: OMFS; surgery; research; innovation; interdisciplinary; cosmetic; pharmacology; cancer; repair; nerve; TMJ; rehabilitation; orthognathic; disorder; bleeding

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Physiotherapy and Therapeutic Exercise in Modern Clinical Practice

edited by Andoni Carrasco Uribarren,

Luis Ceballos-Laita

and

Carolina Climent-Sanz

submission deadline 20 Jun 2026 | Viewed by 134 | Submission Open

Keywords: exercise therapy; physiotherapy; therapeutic exercise; musculoskeletal disorders; musculoskeletal rehabilitation; pain management; patient-centered care; physiotherapy; rehabilitation technology

(This special issue belongs to the Section Orthopedics)

Sepsis: Clinical Advances and Practical Updates

edited by

Paolo Formenti

submission deadline 20 Jun 2026 | Viewed by 131 | Submission Open

Keywords: sepsis pathophysiology; host immune response; biomarkers for sepsis; early sepsis diagnosis; immunotherapy in sepsis; antimicrobial stewardship

(This special issue belongs to the Section Intensive Care)

Chronic Kidney Disease: From Diagnosis to Treatment

edited by Debra Hain

submission deadline 20 Jun 2026 | 1 articles | Viewed by 115 | Submission Open

Keywords: chronic kidney disease; type 2 diabetes; diabetic complications; hemodialysis; nephrology nursing; older adults; palliative care; therapy; hypertension

(This special issue belongs to the Section Nephrology & Urology)

Obsessive–Compulsive Disorder: Clinical Advances and Future Perspectives—Second Edition

edited by Andrea Fagiolini

submission deadline 20 Jun 2026 | Viewed by 106 | Submission Open

Keywords: obsessions– compulsions; anxiety; OCD symptoms; treatment options; functional impairment

(This special issue belongs to the Section Mental Health)

Pediatric Ophthalmology: Current Progress and Future Options

edited by

Claudia Yahalom

and

Nir Erdinest

submission deadline 20 Jun 2026 | Viewed by 101 | Submission Open

Keywords: pediatric ophthalmology; genetic eye diseases; gene therapy; genetic counseling; telemedicine; diagnostic tools; blindness in childhood; congenital cataract; visual rehabilitation; myopia control

(This special issue belongs to the Section Ophthalmology)

Innovations in Neurorehabilitation—2nd Edition

edited by

Syoichi Tashiro

submission deadline 20 Jun 2026 | Viewed by 96 | Submission Open

Keywords: clinical neurophysiology; neuroengineering; robotics; non-invasive transcranial brain stimulation; spinal stimula-tion; regenerative rehabilitation; neuroimaging; brain– computer interface; brain-spinal interface; virtual reality; higher-level cognitive functions; vision rehabilitation

(This special issue belongs to the Section Clinical Rehabilitation)

Contemporary Issues and Emerging Trends in Colorectal Surgery

edited by

Marco Caricato

and

Gianluca Mascianà

submission deadline 20 Jun 2026 | Viewed by 92 | Submission Open

Keywords: abdominal surgery; minimally invasive surgery; colorectal surgery; colorectal cancer; inflammatory bowel disease; image-guided surgery; transational research; artificial intelligence; operative endoscopy; screening; early diagnosis; ERAS

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Research on Minimally Invasive Spine Surgery

edited by Daniel Fahim

submission deadline 20 Jun 2026 | Viewed by 90 | Submission Open

Keywords: minimally invasive spine surgery; spine tumors; spine trauma; spine fractures; lumbar stenosis; lumbar spondylolisthesis; lumbar disc herniation; lumbar radiculopathy; thoracic disc herniations; cervical radiculopathy

(This special issue belongs to the Section Orthopedics)

Clinical Insights in Pediatric Dentistry

edited by

Giulia Orilisi

submission deadline 20 Jun 2026 | Viewed by 89 | Submission Open

Keywords: pediatric dentistry; caries management; dental trauma; preventive dentistry; behavior management; interdisciplinary care; clinical innovations

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Advances in Rhinosinusitis and Nasal Polyposis: From Emerging Trends and Therapeutic Opportunities to Surgery

edited by Gian Luca Fadda, Giovanni Cavallo and

Giuseppe Guida

submission deadline 20 Jun 2026 | Viewed by 88 | Submission Open

Keywords: nasal polyps; chronic rhinosinusitis; asthma; endoscopic sinus surgery; anatomical variation; biologic treatment; type-2 inflammation; paranasal sinuses; CRSwNP; late response; long term; remission; dupilumab; control

(This special issue belongs to the Section Otolaryngology)

Endoscopic Innovations in Gastrointestinal Diseases: From Diagnosis to Therapy

edited by Mattia Brigida and Gianluca Andrisani

submission deadline 20 Jun 2026 | Viewed by 85 | Submission Open

Keywords: endoscopic innovation; gastrointestinal diseases; advanced endoscopic imaging; therapeutic endoscopy; artificial intelligence; minimally invasive therapy; personalized medicine

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Displaying special issue 1151-1200 on page 24 of 31.

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