Special Issue "Skin Disease and Comorbidities"
Deadline for manuscript submissions: 31 December 2020.
Interests: inflammatory skin disease; psoriasis; atopic dermatitis; cytokine; neutrophil
The skin is one of the largest immune organs that involves innate and acquired immune systems and thus is able to respond to exogenous stimuli, producing large amounts of proinflammatory cytokines, resulting in systemic inflammation. In psoriasis, one of the intractable inflammatory cytokine-mediated skin disorders, the average life span is 6 years shorter compared to that of the population without history of psoriasis; this is due to the cerebro-cardiovascular complications. Additionally, eczema patients have an increased risk of cardiovascular disorders. Several studies have shown that severe inflammatory skin disorders are deeply connected to systemic complications such as arteriosclerosis, cardiomyopathy, abnormal fat metabolism, renal sclerosis, and systemic amyloidosis, leading to the concept of “inflammatory skin march”—intimate relations between skin inflammation and complications. Here we welcome the clinical evidence and cases focusing on systemic inflammatory changes and systemic organ diseases complicated by inflammatory skin disorders.
Prof. Dr. Keiichi Yamanaka
Manuscript Submission Information
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- inflammatory skin disease
- atopic dermatitis
- internal organs