Infective Endocarditis: What Is New in the Clinical Research?

Dear Colleagues,

Infective endocarditis (IE) is a rare disease that still poses significant challenges. Despite significant advances made in medical knowledge and technology that have improved the diagnosis and treatment of infectious diseases in the last few decades, IE is still associated with significant morbidity and mortality, while its epidemiology is changing. Patients are older in age, the microbiology has changed due to the increase in healthcare-associated infection, leading to the more frequent identification of Gram-negative microorganisms as causes of IE. On the other hand, the increasing rates of antimicrobial resistance have resulted in the more frequent diagnosis of IE caused by microorganisms with few therapeutic options. Finally, the increasing use of immunosuppression in patients with cancer, autoimmune diseases, and transplantation has led to an increase in the diagnosis of IE caused by rare pathogens. This Special Issue will focus on the current clinical research on IE and present the latest data on the changing epidemiology, microbiology, diagnostic methods, and treatment of IE as well as its outcomes.

Dr. Petros Ioannou
Guest Editor

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