Big Data and Precision Medicine Series II: Human Papillomavirus and Cancer

Dear Colleagues,

Human papillomaviruses (HPV) have been recognized as the major risk factor for development of nearly all cervical cancers, and a significant fraction of other human carcinoma, arising from mucosal squamous epithelia, including anal, vaginal, vulvar, penile and oropharyngeal cancer. Long-term persistent infections, the integration of viral DNA into the human genome, and constitutive expression of viral oncoproteins contribute to many heterogeneous molecular changes in infected cells, leading to cancer development and progression. Many genetic and epigenetic alterations, as well as complex molecular networks have been identified by “omics” technologies in HPV-related cancer. We welcome submissions of research and review articles on the “omic” landscape of HPV-related cancer to gather current knowledge on the complex process of viral oncology.

Dr. Maria Lina Tornesello
Dr. Franco M. Buonaguro
Guest Editors

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