Chronic Kidney Disease: Clinical Updates and Perspectives, Opportunities and Challenges

Dear Colleagues,

Chronic kidney disease (CKD) is a devastating condition that has reached epidemic levels due to the aging of the population and the increasing prevalence of diabetes mellitus, hypertension and obesity. The global estimated prevalence of CKD is 13.4%. It has a substantial impact on morbidity and mortality: the Global Burden of Diseases study estimated that 1.2 million deaths were due to kidney failure and 18 million years of life lost from cardiovascular diseases were directly attributable to CKD. Even in early stages, CKD is associated with increased cardiovascular morbidity and mortality. Managing CKD-associated cardiovascular risk and the preservation of kidney function can improve outcomes and can be achieved through non-pharmacologic strategies and CKD-targeted pharmacological interventions. Despite different management strategies, the progression of CKD to end-stage kidney disease (ESKD) currenty remains inevitable.

In this Special Edition, we aim to focus on novel strategies that delay CKD progression and improve the life expectany of CKD patients by reducing cardiovascular morbidity and mortality and by better management of ESKD in dialysed and transplanted patients.

The Editor of this Special Edition invites you to submit relevant papers for consideration and expeditious publication after a vigorous peer review. We particularly welcome papers discussing novel concepts in the era of fighting ESKD. All original investigations, including both clinical and basic science studies, as well as meta-analyses and review papers will be considered.

Dr. Botond Csiky
Guest Editor

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