Cerebral Embolic Protection for Transcatheter Aortic Valve Replacement—Present Status and Perspective

Dear Colleagues,

Stroke is a major complication. Transcatheter aortic valve replacement (TAVR) is associated with a substantial risk of stroke, increasing the acute and long-term morbidity and mortality. Cerebral embolic protection with different devices has been linked to a reduction in the size and number of new ischemic cerebral lesions documented by magnetic resonance imaging. In addition, large meta-analyses have supported the idea that TAVR with the use of cerebral embolic protection may be associated with a reduction in clinical stroke. However, the definition of stroke substantially differs between trials and is largely dependent on the neurological assessment. In addition, no risk criteria have been reported so far. This Special Issue addresses the present status of cerebral embolic protection during TAVR and will provide a future perspective. We kindly invite scientific groups dedicated to reducing the risk of stroke during TAVR by technical or pharmacological treatment strategies to submit their manuscript. In addition, we want to address groups studying clinical and imaging criteria for stroke assessment and experts to provide their future perspectives addressing this important topic.

Prof. Dr. Jochen Wöhrle
Dr. Antonio Miceli
Guest Editors

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