The Management of Psoriatic Arthritis: Interface between Rheumatology and Dermatology, Early Diagnosis and Monitoring of Disease Activity

Dear Colleagues,

Psoriasis (PsO) is one of the most common inflammatory skin diseases and predisposes to developing psoriatic arthritis (PsA). Up to one-third of PsO patients develop PsA in their lifetime. Early diagnosis and early treatment are two cornerstones to reach clinical remission and to stop articular damage. In patients with poor prognostic factors, such as polyarthritis, dactylitis, and joint damage, rapid initiation of conventional or biological disease-modifying antirheumatic drugs is strongly recommended. Currently, integrated rheumatological–dermatological clinical evaluation could be crucial for early referral of PsO patients with articular symptoms, for tailored therapies that could work for skin and joints, and for highlighting minimal psoriasis in early seronegative arthritis. PsA is a clinically heterogeneous condition of skin, joint, enthesis, and bone, usually associated with systemic comorbidities that contribute to the worsening of pain and quality of life. In this setting, imaging, particularly ultrasonography and MRI, could assist clinicians in differentiating between symptoms related to PsA and symptoms related to comorbidities or mimickers diseases (e.g., osteoarthritis and fibromyalgia).

Dr. Alen Zabotti
Guest Editor

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