Clinical Outcomes and Emerging Strategies in Neovascualr Age-Related Macular Degeneration
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Ophthalmology".
Deadline for manuscript submissions: 15 December 2026 | Viewed by 418
Editor
Interests: age-related macular degeneration; retinal imaging biomarkers; intravitreal therapy; vitreoretinal surgery; diabetic retinopathy; retinal vascular disorders; real-world evidence; translational retina research
Special Issue Information
Dear Colleagues,
Background and history of this topic:
Neovascular age-related macular degeneration (AMD) is a leading cause of central vision loss worldwide. Intravitreal anti–vascular endothelial growth factor (VEGF) therapy has transformed management over the past two decades; however, challenges remain, including treatment burden, incomplete response, and long-term disease control.
Aim and scope of the Special Issue:
This Special Issue highlights clinically and translationally relevant research focused on exudative retinal disorders, with an emphasis on neovascular AMD and related choroidal neovascular conditions.
Cutting-edge research:
Topics of interest include next-generation anti-VEGF agents, tyrosine kinase inhibitors, angiopoietin/Tie-2 pathway modulators, gene-based therapies, sustained-delivery and implantable platforms, complement pathway modulation, and strategies targeting inflammation or subretinal fibrosis. Additionally, studies exploring imaging-derived biomarkers, predictors of treatment response, and real-world visual outcomes are encouraged.
Types of papers solicited:
We welcome original clinical studies, randomized and observational analyses, prospective and retrospective cohorts, and registry- and claims-based investigations.
Dr. Raziyeh Mahmoudzadeh
Guest Editor
Manuscript Submission Information
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Keywords
- neovascular age-related macular degeneration
- exudative retinal disease
- anti-VEGF therapy
- tyrosine kinase inhibitors
- angiopoietin/Tie-2 modulation
- gene therapy
- sustained-release platforms
- complement pathway inhibition
- real-world clinical outcomes
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