Molecular Research of Host-Pathogen Interactions
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Microbiology".
Deadline for manuscript submissions: 31 July 2026 | Viewed by 114
Special Issue Editors
Interests: alternative antimicrobials; molecular microbiology; biofilm modulation; host–pathogen interactions; antibacterial nanoparticles
Special Issues, Collections and Topics in MDPI journals
Interests: microbiology; immunology; virulence factors; pathogens; antimicrobial materials
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Host–pathogen interactions represent a dynamic area of biological research, with major progress in understanding the molecular mechanism between invading pathogens and host defenses.
Multi-omics approaches—integrating genomics, transcriptomics, proteomics, and metabolomics—now allow researchers to map infection processes, revealing the regulatory networks pathogens use to establish and maintain infection. In parallel, advanced computational strategies—including network medicine, machine learning, mathematical modeling, and systems-level analysis—have improved the ability to predict host–pathogen interactions, anticipate infection outcomes, and prioritize candidate therapeutic targets. However, infectious agents continue to find new ways to overcome defense mechanisms and trigger an infectious process. Infectious diseases remain major causes of mortality globally. This Special Issue focuses on the latest discoveries in pathogenesis and host responses, but also on new findings to combat their actions by modulating their interaction during infectious process. Original research articles and reviews regarding latest virulence modulation, host signaling, infectious process manipulation or treatment approaches at the cellular and molecular level are welcome.
The scope of this Special Issue includes, but is not limited to, the following topics:
- Bacteria-host signaling
- Chronic infections
- Omics-approaches to study infection
- Virulence modulation
- Biofilms
- Quorum Sensing
- Host immunity during infection
- Infection control
- New targets for resistant pathogens
- Molecular communication during infection
- Model systems in host–pathogen studies
Dr. Alina Maria Holban
Dr. Carmen Curutiu
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- host–pathogen interactions
- host immunity during infection
- new targets for resistant pathogens
- molecular communication during infection
- model systems in host–pathogen studies
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