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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advanced Oxidation Processes and Biodegradation for Emerging Contaminants Treatment

edited by

Guilong Peng

and

Chengdu Qi

submission deadline 20 Jun 2025 | 7 articles | Viewed by 19163 | Submission Open

Keywords: advanced oxidation processes; persistent organic compounds; water pollution control; biodegradation; emerging contaminants; water treatment; wastewater treatment; toxicity assessment

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Peptides as Biochemical Tools and Modulators of Biological Activity

edited by

Annamaria Aloisio

submission deadline 20 Jun 2025 | 4 articles | Viewed by 19073 | Submission Open

Keywords: peptides; phage display; stem cells; mesenchymal stromal cells; cancer; leukemia; tumor targeting; drug delivery

(This special issue belongs to the Section Molecular Biology)

New Challenges of Parkinson’s Disease

edited by

Cristina Agliardi

and

Franca Rosa Guerini

submission deadline 20 Jun 2025 | 8 articles | Viewed by 18723 | Submission Open

Keywords: Parkinson’ s disease; neurodegeneration; synuclein; diagnosis; genetics; epigenetics; extracellular vesicles; biomarkers; treatments; rehabilitation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

High-Density Lipoproteins in Health and Disease

edited by

Ilaria Zanotti

submission deadline 20 Jun 2025 | 6 articles | Viewed by 18271 | Submission Open

Keywords: omics; protein; lipid; cardiovascular; neurodegenerative disease; inflammation; preclinical studies; therapy

(This special issue belongs to the Section Molecular Biology)

Skin Diseases: From Molecular Mechanisms to Pathology

edited by

Alessandro Terrinoni

submission deadline 20 Jun 2025 | 8 articles | Viewed by 17421 | Submission Open

Keywords: skin diseases; immunology; genetics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Fractalkine (CX3CL1) and Its Chemoattractant and Adhesion Molecule Properties in Health and Disease

edited by

Dariusz Szukiewicz

submission deadline 20 Jun 2025 | 8 articles | Viewed by 17178 | Submission Open

Keywords: fractalkine; transmembrane fractalkine; soluble fractalkine; fractalkine receptor; CX3CL1-CX3CR1 signaling; inflammation; chemokine; cell adhesion; chemotaxis; immune response; angiogenesis; implantation; atherosclerosis; carcinogenesis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Novel Therapeutic Targets of Solid Cancer

edited by

Valentina De Falco

submission deadline 20 Jun 2025 | 6 articles | Viewed by 17150 | Submission Open

Keywords: cancer; signal transduction; kinase inhibitors; targeted therapy; precision medicine; drug resistance; survival; cell cycle; cell reprogramming; stem cells; immunotherapy

(This special issue belongs to the Section Molecular Oncology)

Mechanism of Redox Signal Transduction in Plants

edited by

Yi Han

and

Kangdi Hu

submission deadline 20 Jun 2025 | 3 articles | Viewed by 16204 | Submission Open

Keywords: reactive oxygen species; reactive nitrogen species; hydrogen sulfide; persulfidation; nitrosation; sulfenylation; redox modification; redox signaling

(This special issue belongs to the Section Molecular Plant Sciences)

Invasion and Metastasis in Brain Cancer

edited by

Aleksandra Glogowska

and

Saeid Ghavami

submission deadline 20 Jun 2025 | 5 articles | Viewed by 16179 | Submission Open

Keywords: metastatic tumor; advanced cancer; blood– brain barrier; brain microenvironment; extracellular matrix; invadopodia; proteins posttranslational modifications

(This special issue belongs to the Section Molecular Oncology)

Stress-Related Disorders and Depression: From Molecular Basis to Therapy (2nd Edition)

edited by

Irena Nalepa

and

Agnieszka Zelek-Molik

submission deadline 20 Jun 2025 | 6 articles | Viewed by 14674 | Submission Open

Keywords: psychobiology of stress; depression; posttraumatic stress disorder; anxiety disorders; animal models; biogenic monoamines; glucocorticoids; inflammation; antidepressant and anxiolytic drugs

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Mechanisms of Somatic Cell Cloning and Other Assisted Reproductive Technologies in Mammals

edited by

Marcin Samiec

and

Maria Skrzyszowska

submission deadline 20 Jun 2025 | 8 articles | Viewed by 14591 | Submission Open

Keywords: somatic cell nuclear transfer (SCNT); SCNT-based cloning; assisted reproductive technology (ART); in vitro embryo production (IVP); in vitro fertilization (IVF); intracytoplasmic sperm injection (ICSI); in vivo embryo production

(This special issue belongs to the Section Molecular Biology)

Thyroid-Related Diseases: Molecular Pathology, Diagnosis and Treatment: 2nd Edition

edited by

Maurizio Martini

and

Vincenzo Fiorentino

submission deadline 20 Jun 2025 | 4 articles | Viewed by 14390 | Submission Open

Keywords: thyroid disease; thyroid nodules; thyroid cancer; thyroid carcinoma; thyroid radiology; thyroid– gut axis; autoimmune thyroid disorders; thyroid hormone; molecular mechanisms; molecular tests

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Machine Learning in Disease Diagnosis and Treatment

edited by

Makrina Karaglani

submission deadline 20 Jun 2025 | 13 articles | Viewed by 13851 | Submission Open

Keywords: machine learning; diagnosis; treatment; algorithm; predictive; artificial intelligence

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Role of Microorganisms and Their Metabolites in Agriculture, Food and the Environment: 2nd Edition

edited by

Barbara Sokolowska

submission deadline 20 Jun 2025 | 8 articles | Viewed by 13815 | Submission Open

Keywords: fermentation; biopreservation; biocontrol; biodegradation; bioremediation; bioaugmentation; omic-technologies

(This special issue belongs to the Section Molecular Microbiology)

Oral and Dental Infectious Diseases: Molecular Pathology, Diagnosis and Therapy

edited by

Hiromichi Yumoto

and

Keiji Murakami

submission deadline 20 Jun 2025 | 8 articles | Viewed by 13751 | Submission Open

Keywords: oral; dental; periodontitis; tooth decay; periodontal diseases; gingivitis; oral microorganism; oral infections; dental infections; dental caries; microbial pathogenicity; Porphyromonas gingivalis; antimicrobials; oral biofilm

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Endometriosis: Focusing on Molecular and Cellular Research

edited by

Alfonso Baldi

submission deadline 20 Jun 2025 | 7 articles | Viewed by 13278 | Submission Open

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Molecular Biology in Forensic Science: Past, Present and Future, 2nd Edition

edited by

Francesco Sessa

and

Monica Salerno

submission deadline 20 Jun 2025 | 5 articles | Viewed by 13179 | Submission Open

Keywords: genetics and molecular biology; forensic molecular biology; forensic and biological sciences; forensic genetics; aging and genetics; molecular biology and pharmacology; molecular biology and toxicology; translational pharmacology; biochemistry

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Adipose Tissue and Gene Expression

edited by

Margherita Maffei

and

Gaia Scabia

submission deadline 20 Jun 2025 | 8 articles | Viewed by 13121 | Submission Open

Keywords: adipose tissue dysfunction; lipomatosis; fat distribution; lipodystrophy; micro-RNA; dysmetabolism; diet; inflammation; rare disease; transcription

(This special issue belongs to the Section Molecular Biology)

Nitric Oxide Signalling in Plants

edited by

Mun Bong-Gyu

submission deadline 20 Jun 2025 | 5 articles | Viewed by 13049 | Submission Open

Keywords: nitric oxide; NO-mediated transcriptome; post-transcription modification; S-nitrosylation; N assimilation; NO homeostasis; gaseous NO; cellular signaling; nitric oxide signaling; transcription factors (TFs)

(This special issue belongs to the Section Molecular Plant Sciences)

Muscle Atrophy: From Bench to Bedside 2.0

edited by

Daniel Taillandier

submission deadline 20 Jun 2025 | 3 articles | Viewed by 12844 | Submission Open

Keywords: muscle atrophy; human diseases; proteolysis; protein synthesis; proteolytic systems system; therapeutic strategies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Angiotensin in Human Health and Diseases

edited by

Helmy M. Siragy

submission deadline 20 Jun 2025 | 4 articles | Viewed by 12263 | Submission Open

Keywords: renin– angiotensin– aldosterone system; angiotensin subtype receptors; cardiovascular disease; kidney diseases; stroke; metabolic abnormalities; obesity and adipose tissue; oxidative stress and inflammation; blood pressure and salt sensitivity

(This special issue belongs to the Section Molecular Biology)

Application of Biotechnology to Dental Treatment

edited by

Satoshi Komasa

and

Yoshiya Hashimoto

submission deadline 20 Jun 2025 | 6 articles | Viewed by 11991 | Submission Open

Keywords: biotechnology; implant material; titanium; zirconia; PEEK; in vitro; in vivo

(This special issue belongs to the Section Materials Science)

New Insights into Cardiac Ion Channel Regulation 3.0

edited by

Ademuyiwa S. Aromolaran

and

Brian P. Delisle

submission deadline 20 Jun 2025 | 5 articles | Viewed by 11835 | Submission Open

(This special issue belongs to the Section Molecular Biology)

Postharvest Biology and Molecular Research of Fruits

edited by

Xiangbin Xu

submission deadline 20 Jun 2025 | 6 articles | Viewed by 11812 | Submission Open

Keywords: postharvest biology; fruit; storage technologies; molecular mechanisms; senescence; chilling injury; browning; nutrition; disease; toxin

(This special issue belongs to the Section Molecular Plant Sciences)

Advanced Research on Regenerative Medicine

edited by

Alberto Ruffilli

and

Cesare Faldini

submission deadline 20 Jun 2025 | 5 articles | Viewed by 11442 | Submission Open

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Research on Prostate Cancer

edited by

Yaser Gamallat

submission deadline 20 Jun 2025 | 7 articles | Viewed by 11223 | Submission Open

Keywords: prostate cancer; molecular biology; genomics; biomarkers; signaling pathways; precision medicine; treatment resistance; epigenetics; therapeutic targets

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Plant Genome Editing

edited by Lei Gao

submission deadline 20 Jun 2025 | 5 articles | Viewed by 11161 | Submission Open

Keywords: plant genome editing; Cas9/Cas12a; CRISPR/CRISPRa/CRISPRi; anti-CRISPR; gene editing; off target impact; prime editing; bioinformatics/database

(This special issue belongs to the Section Molecular Plant Sciences)

Forward in Vasculitis: Genetics and Beyond

edited by

Marija Jelusic

submission deadline 20 Jun 2025 | 5 articles | Viewed by 10730 | Submission Open

Keywords: systemic vasculitides; ethiopathogenesis; risk factors; genetics; genomics; proteomics; transcriptomics; epigenetics; molecular pathways; novel therapeutic strategies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Insight into Novel Coatings: Design, Synthesis, and Applications

edited by

Dmitry V. Mashtalyar

and

Konstantine V. Nadaraia

submission deadline 20 Jun 2025 | 3 articles | Viewed by 10683 | Submission Open

Keywords: composite coatings; protective coatings; antibacterial coatings; superhydrophobic coatings; superhydrophilic coatings; anti-icing coatings; bioactive coatings; photocatalytic coatings

(This special issue belongs to the Section Materials Science)

Molecular Insights into Hair Regeneration

edited by

Jong-Hyuk Sung

submission deadline 20 Jun 2025 | 5 articles | Viewed by 10417 | Submission Open

Keywords: hair loss; androgenic alopecia; alopecia areata; cell therapy; antibody therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Neuroinflammation and Neurodegeneration: Molecular Mechanism and Novel Therapy

edited by

Chih Hung Lo

submission deadline 20 Jun 2025 | 5 articles | Viewed by 10303 | Submission Open

Keywords: neuroinflammation; neurodegeneration; neuroimmunology; toxic protein aggregates; autolysosomal dysfunction; metabolic defects; aberrant receptor signaling; neuron-glia interactions; glia-immune interactions; omics characterizations; therapeutic development; biomarker discovery

(This special issue belongs to the Section Molecular Neurobiology)

Polymers, Polymer Blends, and Polymeric Drug Release Systems with Antiviral or Antibacterial Effect—2nd Edition

edited by

Piotr Dobrzynski

submission deadline 20 Jun 2025 | 5 articles | Viewed by 10289 | Submission Open

Keywords: antimicrobial polymers; antifungal polymers; antiviral polymers; polymers as drug delivery systems; application of biocide polymers; biocide polymers coatings and surfaces; advantages and disadvantages of biocide polymers; mode of action of biocide polymers

(This special issue belongs to the Section Macromolecules)

Physiology and Molecular Biology of Plant Stress Tolerance: 2nd Edition

edited by

De-Guo Han

submission deadline 20 Jun 2025 | 15 articles | Viewed by 10282 | Submission Open

Keywords: plant– pathogen interactions; biotic and abiotic stress; plant innate immunity; phytohormones; genes

(This special issue belongs to the Section Molecular Plant Sciences)

Natural Compounds: Advances in Antimicrobial Activity

edited by

Carlo Genovese

and

Francesco Pegreffi

submission deadline 20 Jun 2025 | 6 articles | Viewed by 10267 | Submission Open

Keywords: natural compounds; multidrug-resistant microorganisms; biofilm; synergistic effect; nanotechnologies; delivery systems; machine learning; clinical infections

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Research on Embryo Developmental Potential

edited by

Jan Tesarik

submission deadline 20 Jun 2025 | 10 articles | Viewed by 10140 | Submission Open

Keywords: embryo developmental potential; oocyte quality; sperm quality; non-invasive techniques; molecular biomarkers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Research on Gynecological Cancers: Ovarian Cancer, Endometrial Cancer, and Gestational Trophoblastic Disease

edited by Laura Mariuzzi,

Alessandro Mangogna

and

Maria Orsaria

submission deadline 20 Jun 2025 | 6 articles | Viewed by 10096 | Submission Open

Keywords: ovarian cancer; endometrial cancer; gestational trophoblastic disease; prognostic factors; oncogenes; molecular genetics and genomics; DNA genotyping; cancer stem cells; epigenomics; signaling pathways; extracellular vesicles; tumour heterogeneity; tumour microenvironment; immune checkpoint inhibitors; new targets; molecular target

(This special issue belongs to the Section Molecular Oncology)

Mental Disorders and Translational Psychiatry: From Neurobiology to Therapeutic Perspective

edited by Lionella Palego and

Valerio Dell’Oste

submission deadline 20 Jun 2025 | 4 articles | Viewed by 10062 | Submission Open

Keywords: mental disorders; illness heterogeneity; comorbidity; treatment resistance; neurobiology; applied neuroscience; translational psychiatry; peripheral biomarkers

(This special issue belongs to the Section Molecular Neurobiology)

The Microbiota and Its Association with Cellular Transformation and Metabolic Changes, 2nd Edition

edited by

Davide Zella

and

Francesca Benedetti

submission deadline 20 Jun 2025 | 2 articles | Viewed by 9611 | Submission Open

Keywords:

(This special issue belongs to the Section Molecular Microbiology)

Schizophrenia: From Molecular Mechanism to Therapy

edited by

Yael Abreu-Villaça

submission deadline 20 Jun 2025 | 4 articles | Viewed by 9486 | Submission Open

Keywords: schizophrenia; neurodevelopmental disorders; therapeutic approaches; drug of abuse; mental disorders

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Mechanisms in Biofilm Formation, Tolerance and Control: 2nd Edition

edited by

Manuel Simões

and Lúcia Chaves Simões

submission deadline 20 Jun 2025 | 8 articles | Viewed by 9416 | Submission Open

Keywords: adhesion; antimicrobial action; antimicrobial resistance; biofilm development; biofilm matrix; biofilm structure; quorum sensing; motility; surfaces

(This special issue belongs to the Section Molecular Microbiology)

Molecular and Cellular Perspectives on Wound Healing

edited by

Ermelindo C. Leal

and

Eugenia Carvalho

submission deadline 20 Jun 2025 | 4 articles | Viewed by 9361 | Submission Open

Keywords: chronic wound healing; scarring; biomarkers; inflammation; angiogenesis; infection; extracellular matrix; biomaterials; tissue regeneration; therapeutic targets; innovative therapies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Food Derived Biomolecules in Reducing the Risk of Diseases

edited by

Furong Tian

submission deadline 20 Jun 2025 | 2 articles | Viewed by 9068 | Submission Open

Keywords: food derived biomolecules; chronic diseases; antioxidant; anti-inflammatory

(This special issue belongs to the Section Bioactives and Nutraceuticals)

New Insights of Biomarkers in Neurodegenerative Diseases

edited by

Ioannis Liampas

submission deadline 20 Jun 2025 | 5 articles | Viewed by 8743 | Submission Open

Keywords: amyloid-β ; tau phosphorylated; tau; GFAP; neurofilaments; TDP-43; progranulin; a-synuclein; magnetic resonance imaging; positron emission tomography; dopamine transporter scan

(This special issue belongs to the Section Molecular Neurobiology)

Editorial Board Members’ Collection Series: New Insights into Neuroproteins

edited by

Barbara Mroczko

and

Fabrizio Michetti

submission deadline 20 Jun 2025 | 6 articles | Viewed by 8705 | Submission Open

Keywords: neuroproteins; S100B; glial fibrillary acidic protein; neuron-specific enolase; alpha-synuclein; amyloid proteins

(This special issue belongs to the Section Molecular Neurobiology)

Editorial Board Members’ Collection Series: Stem Cells and Regenerative Medicine

edited by

Mark L. Weiss

Maciej Kurpisz

and

Alessandra Marconi

submission deadline 20 Jun 2025 | 4 articles | Viewed by 8692 | Submission Open

Keywords: stem cells; regenerative medicine; niche; tissue engineering; cell signaling; differentiation; stem cells therapies; cell culture technologies

(This special issue belongs to the Section Molecular Biology)

Molecular Advances in Gut Microbiota and Intestinal Diseases

edited by

Wolfram Manuel Brück

submission deadline 20 Jun 2025 | 3 articles | Viewed by 8570 | Submission Open

Keywords: dysbiosis; homeostasis; intestinal disease; bioactive molecules; gut health

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Perspective in the Molecular Pathways Involved in Acute and Chronic Lung Injury

edited by

Marika Cordaro

submission deadline 20 Jun 2025 | 5 articles | Viewed by 8548 | Submission Open

Keywords: acute lung injury; chronic lung injury; molecular pathways; treatment; therapeutic targets; inflammation; oxidative stress; respiratory disease

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Advances in Psychiatric Therapies

edited by

Władysława Anna Daniel

and

Anna Haduch

submission deadline 20 Jun 2025 | 3 articles | Viewed by 8433 | Submission Open

(This special issue belongs to the Section Molecular Neurobiology)

Biopolymers in Drug and Gene Delivery Systems 3.0

edited by

Yury A. Skorik

submission deadline 20 Jun 2025 | 4 articles | Viewed by 8381 | Submission Open

Keywords: biopolymers; drug delivery; gene delivery; biodegradable polymers; biocompatible polymers; nanomedicine

(This special issue belongs to the Section Macromolecules)

Anticancer Drug Discovery Based on Natural Products

edited by Su-Yun Lyu

submission deadline 20 Jun 2025 | 4 articles | Viewed by 8350 | Submission Open

Keywords: anticancer drug discovery; natural products; phytochemicals; traditional medicine; drug development; preclinical studies; clinical trials

(This special issue belongs to the Section Molecular Pharmacology)

Displaying special issue 551-600 on page 12 of 67.

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