Neuroblastoma: Molecular Pathology, Diagnostics and Therapeutics
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 30 January 2026 | Viewed by 734
Special Issue Editor
Interests: cell signaling; apoptosis; neurotrophins; cytokines; neuroscience
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Neuroblastoma is the most common extracranial solid tumor in children, accounting for 15% of all pediatric cancer-related deaths. Despite advances in multimodal therapy, high-risk neuroblastoma remains a major challenge due to its aggressive nature and resistance to treatment. Recent insights into the molecular pathology of neuroblastoma have revealed key genetic and epigenetic alterations driving tumor progression, including MYCN amplification, ALK mutations, and dysregulation of developmental pathways. These discoveries have paved the way for novel diagnostic and therapeutic strategies aimed at improving patient outcomes.
This Special Issue aims to bring together cutting-edge research on the molecular mechanisms underlying neuroblastoma, innovative diagnostic tools, and emerging therapeutic approaches. We welcome original research articles and reviews covering topics such as tumor heterogeneity, genetic and epigenetic biomarkers, single-cell and multi-omics analyses, and novel imaging techniques. Additionally, we seek contributions on targeted therapies, immunotherapeutic approaches, and personalized medicine strategies designed to overcome drug resistance and improve survival rates.
This Special Issue will compile the latest advancements in neuroblastoma research, providing a comprehensive overview of the field and fostering collaboration among researchers, clinicians, and industry experts. We invite scientists worldwide to contribute their findings and insights to drive the development of innovative neuroblastoma diagnosis and treatment solutions.
Join us in this endeavor to accelerate translational research and improve outcomes for children affected by this devastating disease.
Dr. Simona Dedoni
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Keywords
- neuroblastoma
- solid cancer
- immature nerve cells
- molecular mechanism
- biomarker
- tumor heterogeneity
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