New Research Perspectives in Protein Glycosylation
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: 30 January 2026 | Viewed by 335
Special Issue Editor
Special Issue Information
Dear Colleagues,
Protein glycosylation is a fundamental and highly dynamic post-translational modification that regulates diverse biological processes, including protein folding, stability, intracellular trafficking, and intercellular communication. Recent advances in analytical techniques, glycoengineering, and systems biology have uncovered unexpected complexity and plasticity in glycosylation patterns across species, tissues, and developmental or physiological states. This Special Issue will present new perspectives on the mechanisms, functions, and evolutionary diversity of protein glycosylation. We welcome contributions on emerging glycosylation pathways, atypical or context-dependent glycan structures, glycan-related diseases, and the role of glycosylation in immunity, signaling, and homeostasis. Studies on state-of-the-art methodologies, such as live-cell glycoprotein imaging, glycoproteomics, multi-omics integration, and computational modeling, are particularly encouraged. By integrating insights from molecular biology, structural biology, and biotechnology, this Special Issue will expand our understanding of how the glycosylation landscape is dynamically regulated and how it shapes protein function and organismal physiology.
Dr. Hirokazu Yagi
Guest Editor
Manuscript Submission Information
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Keywords
- glycan function
- glycan structural analysis
- glycoproteomics
- glycoengineering
- systems glycobiology
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