Submit to IJMS Review for IJMS Propose a Special Issue

Journal Menu

Journal Browser

Special Issues

International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

Section

Search by Title/Keyword

Order results

Display

Results per page

Synthesis and Application of Organic Antibacterial Agents

edited by

Barbara Dmochowska

submission deadline 20 Jan 2026 | Viewed by 422 | Submission Open

Keywords: organic antibacterial compounds; synthesis; natural organic compounds; biological activity; active compounds; biological applications

(This special issue belongs to the Section Biochemistry)

Metabolomics Research of Environmental Stress in Plants

edited by

Manish Kumar Patel

and Sonika Pandey

submission deadline 20 Jan 2026 | Viewed by 402 | Submission Open

Keywords: agricultural applications of primary and secondary metabolite; ; crop improvement; integration of metabolomics with genomics and transcriptomics; medicinal plants; natural products in agriculture; plant metabolomics; plant biochemistry; primary metabolites; secondary metabolites; tools and techniques of plant metabolites in agriculture research

(This special issue belongs to the Section Molecular Plant Sciences)

DNA Damage and Repair: Current Research

edited by

Mahara A. Valverde Ramírez

and Emilio Rojas

submission deadline 20 Jan 2026 | 1 articles | Viewed by 401 | Submission Open

Keywords: DNA damage; DNA repair; endogenous compounds; exogenous compounds; therapy

(This special issue belongs to the Section Molecular Genetics and Genomics)

Cognitive Aging: Molecular Perspectives

edited by

Igor Y. Iskusnykh

submission deadline 20 Jan 2026 | Viewed by 395 | Submission Open

Keywords: brain; neuron; aging; neurodegeneration; cognitive neuroscience; inflammation; regeneration; behavioral neuroscience; pharmacology; brain disorders

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms of Animal Reproduction and Development

edited by

Yu-Feng Wang

submission deadline 20 Jan 2026 | Viewed by 385 | Submission Open

Keywords: spermatogenesis; oogenesis; fertilization; embryogenesis; cell division; cell differentiation; stem cell; abnormal development; obesity; cancer

(This special issue belongs to the Section Molecular Biology)

The Plant Phenotyping and Phenomics for Breeding

edited by

Jaeil Lyu

submission deadline 20 Jan 2026 | Viewed by 384 | Submission Open

Keywords: plant phenomics; high-throughput phenotyping (HTP); genotype– phenotype association; non-invasive imag-ing; functional genomics; environmental interactions

(This special issue belongs to the Section Molecular Plant Sciences)

Cellular and Molecular Mechanisms of Cardiovascular and Metabolic Diseases, 3rd Edition

edited by

Paramjit S. Tappia

submission deadline 20 Jan 2026 | Viewed by 372 | Submission Open

Keywords: cardiovascular diseases; metabolic diseases; cellular and molecular mechanisms

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Innovations in Organic Framework Materials: Expanding the Horizons of COFs, MOFs, and HOFs for Advanced Applications

edited by Bhausaheb Dhokale

submission deadline 20 Jan 2026 | Viewed by 355 | Submission Open

Keywords: COF; MOF; HOF; synthesis; molecular applications; porous materials; molecular engineering; membranes; theoretical studies; energy

(This special issue belongs to the Section Materials Science)

Molecular Biology and Diagnosis on Biliary and Pancreatic Cancers

edited by Francesco Vasuri and Luca Saragoni

submission deadline 20 Jan 2026 | Viewed by 349 | Submission Open

Keywords: biliary cancer; pancreatic cancer; histological diagnoses; cytological diagnoses; chromosome aneuploidy; specific genetic mutations

(This special issue belongs to the Section Molecular Oncology)

DNA and RNA Nanostructures for the Assembly of Functional Molecules

edited by

Di Liu

and

Kalevi Kairemo

submission deadline 20 Jan 2026 | Viewed by 347 | Submission Open

Keywords: DNA nanotechnology; RNA nanotechnology; biomolecular engineering; biomimetics

(This special issue belongs to the Section Molecular Nanoscience)

Advances in Plant Cell Dynamics

edited by

Andrei Smertenko

submission deadline 20 Jan 2026 | Viewed by 338 | Submission Open

Keywords: organelles; cellular polarity; cytoskeleton; vesicle trafficking; cell wall synthesis; signalling; differentiation

(This special issue belongs to the Section Molecular Plant Sciences)

Advancements and Trends in Plant Genomics

edited by Rongbin Hu

submission deadline 20 Jan 2026 | Viewed by 332 | Submission Open

Keywords: plant; genomics; next-generation sequencing; third-generation sequencing; CRISPR-Cas

(This special issue belongs to the Section Molecular Plant Sciences)

Advances in Sepsis: Molecular and Biochemical Perspectives

edited by

Akrivi Chrysanthopoulou

submission deadline 20 Jan 2026 | Viewed by 323 | Submission Open

Keywords: sepsis; outcome; molecular diagnosis; machine learning; biochemical biomarkers; targeted immunotherapy; personalized medicine; sepsis inflammatory endotypes

(This special issue belongs to the Section Biochemistry)

New Insight into Bacteriophage and Their Potential Applications

edited by Wilfried Moreira

submission deadline 20 Jan 2026 | Viewed by 319 | Submission Open

Keywords: bacteriophage; phage biology; phage-host interactions; antimicrobial resistance

(This special issue belongs to the Section Molecular Microbiology)

Molecular Research on Autophagy, 2nd Edition

edited by

Maria Ines Vaccaro

submission deadline 20 Jan 2026 | Viewed by 319 | Submission Open

Keywords: ATG molecules; transcriptional and post translational modification; selective pathways; secretory pathways; complexes diseases; degenerative processes; inflammatory diseases; tumorigenesis; metabolism; proteostasis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Optical, Electrical, and Thermal Materials: Recent Advances and Challenges

edited by Luyi Zou

submission deadline 20 Jan 2026 | Viewed by 309 | Submission Open

Keywords: optical materials; electrical materials; thermal materials; molecular structure; molecular composition; structural performance

(This special issue belongs to the Section Materials Science)

Recent Applications of Programmable Nanobiomaterials in Cancer Targeting and Therapy

edited by Wensheng Xie

submission deadline 20 Jan 2026 | Viewed by 300 | Submission Open

Keywords: programmable nanobiomaterials; cancer targeting; cancer combined therapy; tumor imaging; field-responsive nanomaterials

(This special issue belongs to the Section Molecular Biophysics)

Liver Transplantation: Pathogenesis, Therapeutic Strategies and Future Challenges

edited by

Francesco Tandoi

submission deadline 20 Jan 2026 | Viewed by 299 | Submission Open

Keywords: MASLD; transplant oncology; machine perfusion; extended-criteria donors; donors after cardiac death

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Cutting-Edge Advances in Transcriptional Therapy and Nucleic Acid-Based Therapeutics

edited by

Vincenza Barresi

submission deadline 20 Jan 2026 | Viewed by 290 | Submission Open

Keywords: antisense oligonucleotides (ASOs); siRNAs; peptide nucleic acids (PNAs); aptamers; transcriptional therapy; nanocarriers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Latest Molecular and Psycho-Physiological Insights on “Brain Fatigue”

edited by

Takehiko Fujino

and

Masanori Honsho

submission deadline 20 Jan 2026 | Viewed by 290 | Submission Open

Keywords: epigenetics; neurotransmitter including dopamine; mitochondria dysfunction; neuroinflammation; lipidomics including plasmalogen; proteomics including neuropeptide; neural network; cognition abilities; decline in attention; judgement capacity; depressive state

(This special issue belongs to the Section Molecular Neurobiology)

Single-Atom Catalysts for Small Molecule Transformation

edited by Aijuan Han

submission deadline 20 Jan 2026 | Viewed by 279 | Submission Open

Keywords: single-atom catalyst; small molecule transformation; rational design; applications

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Exploring the New Cancer Biomarkers: Progress and Prospects

edited by

Marcelo José Barbosa Silva

submission deadline 20 Jan 2026 | Viewed by 265 | Submission Open

Keywords: prevention; diagnostic; prognostic; response; liquid biopsy; image biomarkers; clinicopathological biomarkers

(This special issue belongs to the Section Molecular Oncology)

The Role of Extracellular Vesicles in Drug Delivery

edited by

Sara Biagiotti

and

Michele Guescini

submission deadline 20 Jan 2026 | Viewed by 264 | Submission Open

Keywords: red blood cells; red blood cell-extracellular vesicles; drug delivery systems; RNA therapies; EV engineering

(This special issue belongs to the Section Molecular Biology)

Recent Advances in Coagulation Proteins

edited by

Arijit Biswas

submission deadline 20 Jan 2026 | Viewed by 259 | Submission Open

Keywords: coagulation proteins; hemostasis; thrombosis; structural biology; Cryo-EM; inherited coagulation disorders

(This special issue belongs to the Section Molecular Biology)

Polymer Materials Related to Food Packaging

edited by

Rosie Yagmur Yegin

submission deadline 20 Jan 2026 | Viewed by 255 | Submission Open

Keywords: polymeric materials; food packaging; biodegradable polymers; active packaging; intelligent packaging; nanocomposites; sustainability; circular economy; barrier properties; life cycle assessment

(This special issue belongs to the Section Macromolecules)

Environmental and Human Adverse Effects of Micro and Nanoplastics: 2nd Edition

edited by

Elena Niccolai

submission deadline 20 Jan 2026 | Viewed by 249 | Submission Open

Keywords: micro and nanoplastics; environmental pollution; micro and nanoplastic toxicity; human health

(This special issue belongs to the Section Molecular Toxicology)

Photosynthesis and Stress Signaling

edited by

Liangsheng Wang

submission deadline 20 Jan 2026 | Viewed by 247 | Submission Open

Keywords: photosynthesis; chloroplasts; stress; signaling

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Insights into Environmental Toxicology in Cancer

edited by

Silvia Vivarelli

submission deadline 20 Jan 2026 | Viewed by 245 | Submission Open

Keywords: environmental carcinogenesis; toxic exposure; exposome; occupational cancer risk; biomarkers of exposure; new approach methodologies (NAMs)

(This special issue belongs to the Section Molecular Oncology)

Advancements in Cytopathology: Challenges and Changes

edited by Panagiota Mikou

submission deadline 20 Jan 2026 | Viewed by 241 | Submission Open

Keywords: cytopathology; cancer diagnosis; cytology; early cancer detection; exfoliative cytology

(This special issue belongs to the Section Molecular Biology)

Neurohormones in Cardiac Fibrosis and Heart Failure

edited by

Helmy M. Siragy

submission deadline 20 Jan 2026 | Viewed by 229 | Submission Open

Keywords: heart failure; neurohormones; cardiac fibrosis; angiotensin II; aldosterone; endothelin; catecholamines

(This special issue belongs to the Section Molecular Biology)

Density Functional Theory and Its Application in Atomic Collision Models

edited by

Feng Wang

submission deadline 20 Jan 2026 | Viewed by 226 | Submission Open

Keywords: density functional theory; time-dependent density functional theory; finite-temperature density functional theory; ensemble density functional theory; atom collision models; electron stopping power

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Effects of Co-Exposure of Pollutants on Animal Models

edited by

Chiara Maria Motta

submission deadline 20 Jan 2026 | Viewed by 224 | Submission Open

Keywords: environmental health; biological systems; toxic exposure; co-exposure; physiological mechanisms; behavioral responses; gene expression; epigenetic effects; molecular research

(This special issue belongs to the Section Molecular Toxicology)

Psoriasis and Associated Complications: Pathogenic Mechanisms, Gene Biomarkers and Treatments

edited by

Anna Michalak-Stoma

submission deadline 20 Jan 2026 | Viewed by 224 | Submission Open

Keywords: psoriasis; autoimmune disease; autoinflammatory disease; psoriatic arthritis; diabetes; hypertension; lipid disorders; obesity; cardiovascular diseases (CVDs); immunological biomarkers; genetic biomarkers; epigenetic biomarkers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Novel Insights into Mitochondrial Signaling and Homeostasis in Metabolic Diseases

edited by Ching-Yi Chen

submission deadline 20 Jan 2026 | Viewed by 209 | Submission Open

Keywords: diabetes mellitus; cardiovascular disease; fatty liver; chronic kidney disease; mitochondrial homeostasis

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Nanomedicine for Diagnostic and Therapeutic Application

edited by

Nicola D'Avanzo

and Antonella Barone

submission deadline 20 Jan 2026 | Viewed by 189 | Submission Open

Keywords: polymeric nanoparticles; lipid nanoparticles; diagnostic; theranostic; targeted drug delivery; nonovesicles; prescion medicine

(This special issue belongs to the Section Molecular Nanoscience)

Molecular Mechanism of Immune Response

edited by Marisa Mariel Fernández

submission deadline 20 Jan 2026 | Viewed by 185 | Submission Open

Keywords: training of the innate immune response; antigen recognition; cell migration; autoimmune processes; cell differentiation; tolerance; molecular responses of epithelial cells to foreign stimuli; alterations in immune checkpoints; modulation of immune responses; mechanisms of hypersensitivity

(This special issue belongs to the Section Molecular Immunology)

Synthetic RNA Biology: Designing Function Through Structure

edited by

Michael T. Wolfinger

submission deadline 20 Jan 2026 | Viewed by 168 | Submission Open

Keywords: structural biology of RNA; rational design of RNA; RNA structure– function relationships; RNA-based molecular devices and switches; functional RNAs

(This special issue belongs to the Section Biochemistry)

Molecular Research on Porous Polymers for Advanced Separation and Analytical Applications

edited by

Dmitrij Bondarev

submission deadline 20 Jan 2026 | Viewed by 163 | Submission Open

Keywords: microporous polymers; molecular imprinting; ion imprinting; separation; porous surfaces; spectroscopy; chromatography

(This special issue belongs to the Section Macromolecules)

Advances in Targeted Therapy and Immunotherapy for Lung Cancer

edited by

Walid Shalata

submission deadline 20 Jan 2026 | Viewed by 135 | Submission Open

Keywords: lung cancer; small-cell lung cancer; non-small-cell lung cancer; targeted therapy; immunotherapy

(This special issue belongs to the Section Molecular Oncology)

Cellulose and Its Applications, 2nd Edition

edited by

Suresh Valiyaveettil

and Ce Sun

submission deadline 20 Jan 2026 | Viewed by 133 | Submission Open

Keywords: cellulose; biomedical applications; nanocomposites; biodegradable polymers; water purification; nanocellulose

(This special issue belongs to the Section Macromolecules)

Molecular Mechanisms and Therapeutic Potential of Natural Compounds

edited by

Magdalena Bartnik

and Adrianna Sławińska-Brych

submission deadline 20 Jan 2026 | Viewed by 127 | Submission Open

Keywords: natural products; biological activity; bioactive compounds; mechanistic study; mechanism of action; drug discovery; pharmacological activity; synergism

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Pathogenesis and Molecular Therapy of Inflammatory Bowel Disease

edited by

Anoop Kumar

submission deadline 20 Jan 2026 | Viewed by 127 | Submission Open

Keywords: intestinal epithelial barrier; gut microbiota; tight junctions; inflammatory bowel disease; mucosal immunity; autophagy; epithelial restitution; host– microbe interaction; barrier dysfunction; gastrointestinal inflammation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms of Tumor Progression and New Therapeutic Strategies for Urological Cancers, 3rd Edition

edited by

Vicenç Ruiz de Porras

submission deadline 20 Jan 2026 | Viewed by 87 | Submission Open

Keywords: prostate cancer; bladder cancer; renal cell carcinoma; upper urinary tract tumors; testicular cancer; predictive and prognostic biomarkers; tumor progression; novel treatment strategies; chemotherapy; immunotherapy; target therapies; drug resistance mechanisms; tumor microenvironment; precision medicine

(This special issue belongs to the Section Molecular Oncology)

Colorectal Cancer—Emerging Trends and Treatment Strategies

edited by Victor Strambu

submission deadline 20 Jan 2026 | Viewed by 84 | Submission Open

Keywords: innovative therapies; colorectal cancer; new therapeutic approach; synchronous tumors

(This special issue belongs to the Section Molecular Oncology)

Mechanisms of Heavy Metal Toxicity: 3rd Edition

edited by

Toshiyuki Kaji

submission deadline 25 Jan 2026 | 9 articles | Viewed by 15388 | Submission Open

Keywords: heavy metal; metal compound; metallothionein; cellular defense mechanism; metal transporter

(This special issue belongs to the Section Molecular Toxicology)

Molecular Mechanisms of Hematologic Disorders

edited by

Valentina Giudice

submission deadline 25 Jan 2026 | Viewed by 644 | Submission Open

Keywords: solid tumors; hematologic disorders; hematology; bone marrow failure; leukemia; myeloma

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Cardiovascular Diseases: Molecular Mechanisms and Potential Therapy (2nd Edition)

edited by

Andrea Ghiroldi

submission deadline 25 Jan 2026 | Viewed by 372 | Submission Open

Keywords: cardiovascular diseases; pathogenic mechanisms; genetics; cardiomyopathy; myocardial infarction; cardiac fibrosis; pharmacogenomics; drug discovery

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Mitochondrial Dysfunction in Disease: Mechanisms, Biomarkers and Emerging Therapies

edited by