Molecular Mechanisms and Therapeutic Potential of Natural Compounds
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".
Deadline for manuscript submissions: 20 January 2026 | Viewed by 3
Special Issue Editors
Interests: natural products; secondary metabolites; anticancer activity; bioactivity-guided isolation; chromatography; LC-MS/MS; NMR; natural drugs; semisynthetic derivatives of natural drugs
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In recent years, there has been an increased interest in natural products, and in many cases the new drugs being designed have pharmacophores based on those specific to natural substances.
Bioactive compounds isolated from natural sources are characterized by relatively low systemic toxicity compared to synthetic drugs and exhibit a variety of pharmacological activities, such as antimicrobial, anti-inflammatory, anticancer, and anti-Alzheimer's properties, as well as affecting the nervous system, modulating enzyme activity, etc. Studies on the biological activity of single compounds in comparison with whole extracts, including studies of synergistic interactions of active ingredients, provide a potential foundation for the development of new therapeutic strategies.
In this Special Issue, we would like to present methods for studying the biological activity of isolated and characterized active natural compounds, with particular emphasis on analyzing the mechanisms underlying these activities. Studies of single substances alone or/and in synergistic studies are particularly welcome.
We invite contributions of both original and review papers to this Special Issue.
Dr. Magdalena Bartnik
Dr. Adrianna Sławińska-Brych
Guest Editors
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Keywords
- natural products
- biological activity
- bioactive compounds
- mechanistic study
- mechanism of action
- drug discovery
- pharmacological activity
- synergism
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