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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Plant Chloroplasts and Mitochondria: Key Organelles for Sustainable Agriculture

edited by

Nunzia Scotti

submission deadline 20 Apr 2026 | 4 articles | Viewed by 8805 | Submission Open

Keywords: ‘ omics’ ; photosynthesis; energy production; crops; climate change; sustainable agriculture; stress response; inter-organelle crosstalk; signaling networks; genetic engineering

(This special issue belongs to the Section Molecular Plant Sciences)

Small Molecule Drug Design and Research: 3rd Edition

edited by

Adel Nefzi

submission deadline 20 Apr 2026 | 5 articles | Viewed by 8587 | Submission Open

Keywords: drug design; diversity-oriented synthesis; combinatorial chemistry; computationally guided synthesis; drug-like compounds; computer modeling techniques

(This special issue belongs to the Section Molecular Pharmacology)

The Role of Protein Kinase in Health and Diseases

edited by

Manuela Loi

submission deadline 20 Apr 2026 | 4 articles | Viewed by 8564 | Submission Open

Keywords: protein kinases; phosphorylation; cancer; neurological disorder; targeted therapies; metabolic diseases

(This special issue belongs to the Section Biochemistry)

Gynecologic Oncology: Molecular Mechanisms and Therapies

edited by

Angel Yordanov

submission deadline 20 Apr 2026 | 4 articles | Viewed by 8364 | Submission Open

Keywords: cervical cancer; endometrial cancer; ovarian cancer; vulvar cancer; carcinogenesis; microinvairment; immunotherapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Pathophysiology and Pharmacology in Psychiatry

edited by

Galila Agam

submission deadline 20 Apr 2026 | 3 articles | Viewed by 8338 | Submission Open

Keywords: psychiatric disorders; mental health; pathophysiology; neuropsychopharmacology; brain

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Advances in Blood Disorders

edited by

Tadej Pajič

submission deadline 20 Apr 2026 | 4 articles | Viewed by 8313 | Submission Open

Keywords: acquired and inherited blood disorders; diagnostic; prognostic and predictive biomarkers; molecular profiling; molecular monitoring; targeted therapy; leukaemia; lymphoma; disorders of haemostasis and thrombosis; genetic predisposition; germline pathogenic variants; molecular mechanisms; (epi)genomics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Recent Progress in Molecular Mechanisms of Sperm Metabolism and Development

edited by Karl Kerns

submission deadline 20 Apr 2026 | 3 articles | Viewed by 8053 | Submission Open

Keywords: sperm development ; germ cell proliferation ; sperm cell metabolism ; seminal fluid biochemical composition ; spermatogenesis ; epididymal maturation ; sperm capacitation ; oocyte activation

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Nanofibrous Biomaterials for Biomedicine and Medical Applications

edited by Jong-Young Kwak

submission deadline 20 Apr 2026 | 3 articles | Viewed by 7530 | Submission Open

Keywords: nanofibers; biomaterials; 3D scaffold; 3D cell culture; tissue engineering; drug release

(This special issue belongs to the Section Materials Science)

Molecular Insights into Antioxidant and Anti-Inflammatory Properties of Bioactive Compounds

edited by

Gang Ye

submission deadline 20 Apr 2026 | 2 articles | Viewed by 7285 | Submission Open

Keywords: antioxidant; anti-inflammatory; bioactive compounds; artificial intelligence; multiomics

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Advances in Epigenetics of Mental Disorders

edited by

Claudio Brasso

submission deadline 20 Apr 2026 | 1 articles | Viewed by 7199 | Submission Open

Keywords: mental disorders; epigenetic; epigenomic; gene– environment interactions

(This special issue belongs to the Section Molecular Neurobiology)

Advanced Therapy Using Human Mesenchymal Stem Cells (MSCs) and MSC Extracellular Vesicles

edited by Tong Ming Liu and Xiaoman Luo

submission deadline 20 Apr 2026 | 3 articles | Viewed by 7154 | Submission Open

Keywords: mesenchymal stem cells; extracellular vesicles; MSCs; MSC-EVs; regenerative medicine

(This special issue belongs to the Section Molecular Biology)

Mitochondrial Functions and Dynamics

edited by

Raffaella Isola

submission deadline 20 Apr 2026 | 1 articles | Viewed by 7066 | Submission Open

Keywords: bioenergetics; mitochondrial biogenesis; mitochondrial morphology; apoptosis; mitophagy; reactive oxygen species; calcium homeostasis; cardiovascular diseases; neurodegenerative diseases; in vitro; cellular; and animal models; myopathies; mitochondria and immune system

(This special issue belongs to the Section Molecular Biology)

Genetic and Epigenetic Analyses in Cancer

edited by Jing Gong

submission deadline 20 Apr 2026 | 6 articles | Viewed by 7001 | Submission Open

Keywords: epigenetics; genetic mutations; chromosomal instability; DNA methylation; histone modifications; non-coding rnas; multi-omics; transcriptomics; proteomics; drug resistance in cancer; cancer biomarkers; therapeutic targets in cancer

(This special issue belongs to the Section Molecular Genetics and Genomics)

Microbiome Modulation Through Probiotics: Molecular Insights and Therapeutic Applications

edited by

Satya Prakash

submission deadline 20 Apr 2026 | 2 articles | Viewed by 6919 | Submission Open

Keywords: live bacterial cells; prebiotic agents; synbiotic formulations; probiotic formulations; microbial dysbiosis; inflammation; oxidative stress; host– microbe interactions

(This special issue belongs to the Section Molecular Microbiology)

Newer Pharmacological Treatment Concepts for Patients with Acute Coronary Syndrome

edited by

Dimitrios Patoulias

submission deadline 20 Apr 2026 | 2 articles | Viewed by 6632 | Submission Open

Keywords: acute coronary syndrome (ACS); molecular studies; antiplatelet; anticoagulant drugs; lipid-lowering therapies

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Signalling in Multitrophic Systems Involving Arthropods

edited by

Francesca Barbero

submission deadline 20 Apr 2026 | 4 articles | Viewed by 6617 | Submission Open

Keywords: insects; plants; microorganisms; communication; symbioses; eavesdropping

(This special issue belongs to the Section Molecular Biology)

The Role of Glycans in Immune Regulation

edited by Senlian Hong

submission deadline 20 Apr 2026 | 2 articles | Viewed by 6501 | Submission Open

Keywords: glycoimmunology; glycotherapy; vaccines; glycan synthesis; immune tolerance

(This special issue belongs to the Section Molecular Immunology)

Protein Folding, Misfolding, and Related Diseases

edited by

Ludmilla Morozova-Roche

submission deadline 20 Apr 2026 | 3 articles | Viewed by 6404 | Submission Open

Keywords: protein folding; misfolding; amyloid; neurodegenerative diseases; chaperons; mechanisms; regulation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecules and Mechanisms of Oxidative Stress Relevant in the Pathophysiology of Diseases

edited by

Cinzia Signorini

submission deadline 20 Apr 2026 | 5 articles | Viewed by 6399 | Submission Open

Keywords: redox-active iron; reactive oxygen species; antioxidants; oxidative damage; biomarkers; degenerative disease

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Antibody–Drug Conjugates

edited by Bing Sun

submission deadline 20 Apr 2026 | 1 articles | Viewed by 6381 | Submission Open

Keywords: antibody– drug conjugate (ADC); cancer treatment; non-oncology indications; antibody selection; payload; linker; conjugation chemistry

(This special issue belongs to the Section Molecular Immunology)

Recent Advances in Molecular Breeding for Drought and Salt Stress Tolerance in Crops: 2nd Edition

edited by

Zhaoshi Xu

submission deadline 20 Apr 2026 | 4 articles | Viewed by 6365 | Submission Open

Keywords: drought; salt; heat; cold; gene regulation; genomic research; multiomics; epigenetics; stress signal transduction

(This special issue belongs to the Section Molecular Plant Sciences)

Wheat Genetics and Genomics: 3rd Edition

edited by

Xiaojun Nie

submission deadline 20 Apr 2026 | 4 articles | Viewed by 6323 | Submission Open

Keywords: wheat; genetics; molecular breeding; genome variation; multiomics

(This special issue belongs to the Section Molecular Plant Sciences)

Recent Research of Phytochemicals in Health and Disease

edited by Sachiko Koyama,

Thomas Heinbockel

and

Vonnie Shields

submission deadline 20 Apr 2026 | 2 articles | Viewed by 6299 | Submission Open

Keywords: phytochemicals with bioactive properties; health; brain function; regeneration; wound healing; treatment; and prevention of diseases; delivery routes and delivery methods; formulation of phytochemicals to overcome their hydrophobic nature and enhance their stability; drugs; supplements to drugs; and supplements for health maintenance; nourishment and phytochemicals; drug side effects; COVID-19

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Understanding of Allergen Exposome

edited by

Fernando Pineda

and

Ruperto Gonzalez-Perez

submission deadline 20 Apr 2026 | 4 articles | Viewed by 6203 | Submission Open

Keywords: allergen exposome; profile allergen exposures; climatic change; airborne allergens; molecular triggers; microbial allergens

(This special issue belongs to the Section Molecular Immunology)

Stem Cells in Health and Disease: 3rd Edition

edited by

Maja Ludvigsen

submission deadline 20 Apr 2026 | 4 articles | Viewed by 5984 | Submission Open

Keywords: stem cell regulation; differentiation; pluripotency; reprogramming; stem cell therapy; cancer stem cell/tumor-initiating cell; therapy resistance; regenerative medicine; metabolic plasticity

(This special issue belongs to the Section Molecular Biology)

Natural Medicines and Functional Foods for Human Health

edited by Qiong Wang

submission deadline 20 Apr 2026 | 2 articles | Viewed by 5853 | Submission Open

Keywords: functional food; natural medicine; traditional Chinese medicine; memory; depression; dementia; Alzheimer’ s disease; Parkinson’ s disease; space medicine; sleeplessness; anti-inflammation

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Genetic, Epigenetic and Microbiota Molecular Insights for Crop Resilience to Abiotic Stress

edited by

Aliki Kapazoglou

submission deadline 20 Apr 2026 | 2 articles | Viewed by 5686 | Submission Open

Keywords: abiotic stress; tolerance; crop resilience; crop sustainability; environmental conditions; climate change; gene regulation; epigenetic mechanisms; microbiota communities; microbiome

(This special issue belongs to the Section Molecular Plant Sciences)

Musculoskeletal Diseases: Advances in Molecular Mechanisms and Therapeutic Approaches

edited by

Jung Eun Kim

submission deadline 20 Apr 2026 | 3 articles | Viewed by 5644 | Submission Open

Keywords: bone; muscle; tendon; cartilage; osteoporosis; sarcopenia; tendinopathy; osteoarthritis; musculoskeletal pathophysiology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Novel Approaches for Tissue Repair and Tissue Regeneration

edited by Srinivas Madduri

submission deadline 20 Apr 2026 | 2 articles | Viewed by 5470 | Submission Open

Keywords: injuries; tissue repair; tissue regeneration; tissue engineering; tissue bioengineering; bioactive biomaterial; cell and gene therapeutics; hydrogel; immune modulation

(This special issue belongs to the Section Molecular Biology)

Natural Products for Neuroprotection and Neurodegeneration

edited by

Patrycja Kupnicka

submission deadline 20 Apr 2026 | 4 articles | Viewed by 5349 | Submission Open

Keywords: natural products; bioactive compounds; neuroprotection; neurodegeneration

(This special issue belongs to the Section Molecular Neurobiology)

Plant Breeding and Genetics: New Findings and Perspectives

edited by

Andrés J. Cortés

submission deadline 20 Apr 2026 | 7 articles | Viewed by 5330 | Submission Open

Keywords: quantitative genetics; classical plant breeding; marker-assisted selection; genomic selection; speed breeding; gene editing and biotechnology

(This special issue belongs to the Section Molecular Plant Sciences)

Natural Active Substances in Human Diseases

edited by

Hyeung-Jin Jang

submission deadline 20 Apr 2026 | 2 articles | Viewed by 5295 | Submission Open

Keywords: natural active substances; bioactive compounds; molecular mechanisms; traditional medicine; metabolic disorders; inflammatory diseases; neurodegenerative diseases

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Micro-Nano Materials for Drug Delivery and Disease Treatment

edited by

Maoquan Chu

submission deadline 20 Apr 2026 | 3 articles | Viewed by 5224 | Submission Open

Keywords: biomaterials; nanoparticle-loaded bacterial cells; nanoparticle-loaded cells; bioimaging and diagnosis; therapy

(This special issue belongs to the Section Molecular Nanoscience)

Germline Stem Cells: New Insights

edited by

Thomas Skutella

submission deadline 20 Apr 2026 | 1 articles | Viewed by 5190 | Submission Open

Keywords: signaling pathway; spermatogonia development; oocyte development; microarray analysis; single-cell sequencing; epigenetic mechanisms; germline stem cell

(This special issue belongs to the Section Molecular Biology)

Advances in Plant Genomics and Genetics: 3rd Edition

edited by

Hengling Wei

submission deadline 20 Apr 2026 | 6 articles | Viewed by 5158 | Submission Open

Keywords: plant genomics; plant genetics; abiotic stresses; salt resistance; genome; next-generation sequencing

(This special issue belongs to the Section Molecular Genetics and Genomics)

Type 1 Diabetes: Molecular Mechanisms and Therapeutic Approach

edited by Preeti Chhabra

submission deadline 20 Apr 2026 | 2 articles | Viewed by 5133 | Submission Open

Keywords: type 1 diabetes; microbiome; proteomics; immunotherapy; β -cell replacement; single-cell sequencing; stem cells; gene editing technologies; tolerance

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Tea and Health

edited by

Mingzhe Yao

and

Kang Wei

submission deadline 20 Apr 2026 | 3 articles | Viewed by 5129 | Submission Open

Keywords: tea plant (Camellia sinensis); molecular mechanism; human health; nutrients; quality-related component; genes identification

(This special issue belongs to the Section Molecular Plant Sciences)

The Blood–Brain Barrier and Neuroprotection

edited by Aruna Sharma and Hari Shanker Sharma

submission deadline 20 Apr 2026 | 3 articles | Viewed by 5077 | Submission Open

Keywords: blood– brain barrier; neurodegenerative diseases; nanoformulations; drug development; delivery systems

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Microbiology in the Omics Era: Genomics, Metagenomics and Computational Insights

edited by

Fei Liu

submission deadline 20 Apr 2026 | 2 articles | Viewed by 5042 | Submission Open

Keywords: microbial genomics; metagenomics; computational biology; antimicrobial resistance; host– microbe interactions; multi-omics integration; bioinformatics tools; machine learning in microbiology

(This special issue belongs to the Section Molecular Microbiology)

Molecular Genetics, Breeding, and Multi-Omics Approaches in Rice Research

edited by

Zakaria Prodhan

submission deadline 20 Apr 2026 | 4 articles | Viewed by 4991 | Submission Open

Keywords: rice genetics and breeding; molecular breeding of rice; rice genomics and proteomics; genes related to abiotic stress tolerance in rice; molecular biology and multi-omics in rice research

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Targets and Immunotherapy for Autoimmune Diseases

edited by

Neetu Srivastava

submission deadline 20 Apr 2026 | 1 articles | Viewed by 4895 | Submission Open

Keywords: autoimmunity; autoimmune diseases; immunotherapy; signaling pathway; molecular targets; antibody; T cells; B cells

(This special issue belongs to the Section Molecular Immunology)

Molecular Perspectives in Nanomedicine

edited by

Stefano Leporatti

submission deadline 20 Apr 2026 | 1 articles | Viewed by 4817 | Submission Open

Keywords: nanomedicine; drug delivery; nano therapy and diagnostics; micro and nanofluidic tools; hybrid nanoparticles; CAR-T nanotechnologies

(This special issue belongs to the Section Molecular Nanoscience)

Techniques and Strategies in Drug Design and Discovery, 3rd Edition

edited by

George Mihai Nitulescu

submission deadline 20 Apr 2026 | 2 articles | Viewed by 4728 | Submission Open

Keywords: drug discovery; drug development; target identification; computational drug design; structure-based drug design; ligand-based drug design

(This special issue belongs to the Section Molecular Pharmacology)

Isolation and Biological Activities of Natural Products: Focus on Molecular Advance

edited by Pedro Ferreira and

Patricia Reboredo-Rodríguez

submission deadline 20 Apr 2026 | 4 articles | Viewed by 4708 | Submission Open

Keywords: natural products; sustainable isolation; biological activities; therapeutic potential; structure-activity relationships; omics technologies; bioavailability; functional foods; green chemistry; molecular docking

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Recent Advances in Polymeric Biomaterials

edited by

Diego Acevedo

submission deadline 20 Apr 2026 | 1 articles | Viewed by 4707 | Submission Open

Keywords: biopolymers; biocomposites; nanomaterials; applications

(This special issue belongs to the Section Materials Science)

Characterization and Biological Function of Plant Extracts

edited by

Simonetta Cristina Di Simone

submission deadline 20 Apr 2026 | 3 articles | Viewed by 4606 | Submission Open

Keywords: plant extracts; phytochemical characterization; bioactive compounds; biological activity; molecular mechanisms; gene expression; pharmacognosy

(This special issue belongs to the Section Bioactives and Nutraceuticals)

False-Positive and False-Negative Laboratory Biomarkers

edited by Michela Salvatici and Lorenzo Drago

submission deadline 20 Apr 2026 | 2 articles | Viewed by 4543 | Submission Open

Keywords: biomarkers; false positives/negatives; protein biomarkers; nucleic acid markers; multi-omics; single-cell sequencing; liquid biopsy

(This special issue belongs to the Section Biochemistry)

Inflammatory Bowel Disease: Focus on Molecular Research

edited by David Meriwether and

Hon Wai Koon

submission deadline 20 Apr 2026 | 2 articles | Viewed by 4507 | Submission Open

Keywords: inflammatory bowel disease; gut microbiota; genomic sequencing; proteomic; lipidomic; metabolomic; therapy; biomarker; animal and organoid model

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Quadruplex DNA and Its Ligands for Disease Treatment

edited by

Ding Li

submission deadline 20 Apr 2026 | 3 articles | Viewed by 4499 | Submission Open

Keywords: quadruplex; i-motif; transcriptional regulation; apoptosis; cancer

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Insights and Treatments for Gynecological Cancers

edited by

Nicoletta D'Alessandris

submission deadline 20 Apr 2026 | 1 articles | Viewed by 4490 | Submission Open

Keywords: gynecological cancers; cancers; endometrial cancers; cervical cancer; tumor microenvironment

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Displaying special issue 2651-2700 on page 54 of 70.

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