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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Research in Functional Nanomaterials

edited by

Łukasz Laskowski

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1778 | Submission Open

Keywords: functional materials; nanomaterials; molecular structure; molecular materials; functional molecules; nanotechnology; self-assembly methods

(This special issue belongs to the Section Molecular Nanoscience)

Molecular Mechanisms of Natural Bioactive Compounds

edited by

Dušanka Kitić

submission deadline 28 Feb 2027 | 2 articles | Viewed by 1759 | Submission Open

Keywords: natural products pharmacology; plant secondary metabolites; molecular mechanisms; phyto-chemicals; signal transduction pathways; structure–activity relationships; natural product

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Research of Host-Pathogen Interactions

edited by

Alina Maria Holban

and

Carmen Curutiu

submission deadline 28 Feb 2027 | 2 articles | Viewed by 1745 | Submission Open

Keywords: host–pathogen interactions; host immunity during infection; new targets for resistant pathogens; molecular communication during infection; model systems in host–pathogen studies

(This special issue belongs to the Section Molecular Microbiology)

Molecular Characterization and Utilization of Plant Genetic Resources

edited by

Roel Rabara

submission deadline 28 Feb 2027 | 3 articles | Viewed by 1732 | Submission Open

Keywords: molecular markers; genetic resources; genomics; transcriptomics; molecular characterization; genetic diversity; transcriptomics; bioinformatics; germplasm enhancement; epigenetics

(This special issue belongs to the Section Molecular Plant Sciences)

Animal Models for Neurobiological Diseases

edited by

Hiroki Toyoda

and

Jana Tchekalarova

submission deadline 28 Feb 2027 | 3 articles | Viewed by 1719 | Submission Open

Keywords: animal models; mice; zebrafish; Alzheimer's disease; Parkinson's disease; multiple sclerosis; neuropsychiatric conditions

(This special issue belongs to the Section Molecular Neurobiology)

Precision Medicine in Cancer: Biomarker and Bioinformatics Research

edited by

Youping Deng

and

Shaoqiu Chen

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1716 | Submission Open

Keywords: precision medicine; cancer biomarkers; bioinformatics; multi-omics; machine learning; tumor heterogeneity

(This special issue belongs to the Section Molecular Informatics)

Advanced Molecular Research on Kidney Diseases

edited by Joan Torras and Laura Martinez Valenzuela

submission deadline 28 Feb 2027 | 4 articles | Viewed by 1708 | Submission Open

Keywords: renal genomics; molecular; proteomics and metabolomics; cellular mechanisms and biomarkers; therapeutic innovations; translational and precision medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Plant Breeding and Biotechnology: From Lab to Field

edited by

Wenlong Bao

submission deadline 28 Feb 2027 | 3 articles | Viewed by 1698 | Submission Open

Keywords: crop improvement; genetic transformation; omics approaches; plant metabolites; plant resistance; plant breeding

(This special issue belongs to the Section Molecular Plant Sciences)

Polymer Composites: Advances and Applications

edited by

Saeid Sahmani

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1652 | Submission Open

Keywords: polymer composites; polymer nanocomposites; biocompatible polymer composites; structure-property relationships; interfacial engineering; molecular design; computational modelling; mechanical performance; advanced applications

(This special issue belongs to the Section Materials Science)

Interplay Between Cytoskeletal Dynamics and Cell Signaling in Cancer

edited by

Aleksandra Glogowska

submission deadline 28 Feb 2027 | 2 articles | Viewed by 1618 | Submission Open

Keywords: cytoskeleton; cancer; organelle function; golgi apparatus; endoplasmic reticulum; mitochondria; post-translational modification; tumor invasion; metastasis; chemoresistance; therapeutic targets

(This special issue belongs to the Section Molecular Oncology)

Decoding the Microbial Influence on Host Gene Expression

edited by

Damian Kołat

and

Mateusz Kciuk

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1608 | Submission Open

Keywords: microbiota; host; gene expression; in silico; bioinformatics; in vitro; in vivo

(This special issue belongs to the Section Molecular Microbiology)

Microfluidic Organ-on-a-Chip: Bridging Drug Discovery to Precision Medicine

edited by Yongjian Ai and Mengqi He

submission deadline 28 Feb 2027 | 2 articles | Viewed by 1599 | Submission Open

Keywords: absorption; distribution; metabolism; excretion; toxicity; host–pathogen; host-immune; pharmacokinetic; pharmacodynamic; absorption; metabolism; toxicity

(This special issue belongs to the Section Molecular Pharmacology)

The Characterization and Application of Enzymes in Bioprocesses, 2nd Edition

edited by

Loredana Marcolongo

submission deadline 28 Feb 2027 | 2 articles | Viewed by 1553 | Submission Open

Keywords: biocatalysts; enzymatic characterization; enzymatic action; protein engineering; biocatalysts application; bioprocessing

(This special issue belongs to the Section Biochemistry)

Genetic Determinants of Drug Response: From Molecular Mechanisms to Precision Therapy

edited by

Pedro Ayuso

submission deadline 28 Feb 2027 | 2 articles | Viewed by 1533 | Submission Open

Keywords: pharmacogenetics; pharmacogenomics; drug response; drug metabolism; precision medicine; biomarkers; adverse drug reactions

(This special issue belongs to the Section Molecular Genetics and Genomics)

Post-Transcriptional Gene Regulation of mRNA and Protein Expression

edited by Greco Hernández

submission deadline 28 Feb 2027 | 2 articles | Viewed by 1488 | Submission Open

Keywords: translational control; protein synthesis; mRNA biochemistry; signal transduction; mTOR pathway; post-transcriptional regulation

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular and Signaling Pathways in Pathological Changes of Esophageal, Gastric and Intestinal Epithelial Cells and Methods of Cell Protective Treatment

edited by

Tomasz Brzozowski

submission deadline 28 Feb 2027 | 2 articles | Viewed by 1466 | Submission Open

Keywords: gastrointestinal epithelial cells; cellular signaling; molecular pathways; cell damage; cell protection; esophageal integrity; gastric secretion; gastric ulcer; duodenal ulcer; intestinal digestion and absorption; intestinal integrity; inflammatory bowel disease; irritable bowel syndrome; ulcerative colitis; Crohn’s disease

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Early Diagnosis and Advanced Therapies of Genetic Disorders

edited by

Milen Velinov

submission deadline 28 Feb 2027 | 2 articles | Viewed by 1459 | Submission Open

Keywords: genetic disorders; rare diseases; disease diagnostics; therapeutic targets; gene variants

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Mitochondrial Bioenergetics and Signaling in Diseases

edited by

Carlos Palmeira

and

Anabela P. Rolo

submission deadline 28 Feb 2027 | 2 articles | Viewed by 1447 | Submission Open

Keywords: mitochondria; bioenergetics; oxidative phosphorylation; mitochondrial signaling; metabolism; reactive oxygen species (ROS); mitochondrial dynamics; mitophagy; calcium signaling; mitochondrial DNA; redox homeostasis; cell death; inflammation; neurodegeneration; cancer metabolism; cardiometabolic diseases; aging; therapeutic targeting

(This special issue belongs to the Section Biochemistry)

Cellular and Molecular Mechanisms of Neuroinflammation

edited by

Maria Anttonietta Panaro

submission deadline 28 Feb 2027 | 2 articles | Viewed by 1435 | Submission Open

Keywords: neuroinflammation; astrocytes; microglia; CNS; cytokines; brain; diseases; immune response

(This special issue belongs to the Section Molecular Neurobiology)

Brain–Organ Axis and Related Neurodegeneration

edited by

Nan-Shan Chang

and

Hieu-Huy Nguyen-Tran

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1381 | Submission Open

Keywords: brain–organ axis; microbiota–gut–brain axis; neurodegenerative diseases; neuroinflammation; signaling pathways and alterations; innate immunity

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Adsorption Mechanisms: Theoretical and Experimental Studies

edited by

Anna Deryło-Marczewska

submission deadline 28 Feb 2027 | 2 articles | Viewed by 1227 | Submission Open

Keywords: adsorption processes; adsorption mechanisms; adsorption equilibria; adsorption kinetics; porous materials; structure—property relationships; theoretical and experimental analysis; environmental, analytical, biomedical and technological applications

(This special issue belongs to the Section Molecular Biophysics)

Tumor Viruses: Infection, Carcinogenesis, and Treatment

edited by

Sherif T.S. Hassan

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1207 | Submission Open

Keywords: tumor viruses; viral oncogenesis; EBV, HPV, KSHV, HBV, HCV, HTLV-1, and MCPyV; virus-associated cancers; merging oncoviruses; viral latency; immune evasion; antiviral therapy; immunotherapy; cancer vaccines; gene-editing technologies

(This special issue belongs to the Section Molecular Microbiology)

Molecular Pathogenesis, Immunobiology, and Treatment of Hematological Malignancies

edited by Tatsuro Jo

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1207 | Submission Open

Keywords: hematological malignancies; molecular pathogenesis; tumor microenvironment; immunogenomics; clonal evolution; biomarkers; immune monitoring; T-cell receptor repertoire; targeted therapy; immunotherapy

(This special issue belongs to the Section Molecular Immunology)

New Molecular Insights into Myeloma

edited by Kotaro Shirakawa

submission deadline 28 Feb 2027 | 2 articles | Viewed by 1197 | Submission Open

Keywords: multiple myeloma; clonal evolution and genetic heterogeneity; epigenomic dysregulation; transcriptional reprogramming; mitochondrial dysfunction; bone marrow microenvironment; tumor microenvironment; immunotherapy resistance; drug resistance; single-cell and spatial analysis

(This special issue belongs to the Section Molecular Oncology)

Molecular Characterization of Glioblastoma: Implications for Diagnosis and Personalized Treatment

edited by Madan Mohan Kwatra

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1173 | Submission Open

Keywords: glioblastoma; diagnosis; molecular characterization; personalized treatment

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Advances in Pathogen Interaction and Host Immunity

edited by

Karolina Kot

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1164 | Submission Open

Keywords: host–pathogen interactions; innate and adaptive immunity; pattern recognition receptors (PRRs); immune signaling pathways; cytokines and interferons; immune evasion mechanisms; molecular pathogenesis; infectious diseases

(This special issue belongs to the Section Molecular Immunology)

Advances in Glyco-Based Anticancer Agents

edited by Pedro Colinas

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1163 | Submission Open

Keywords: carbohydrates; cancer; Warburg effect; glycolysis; enzyme inhibitors; transporters inhibitors; docking simulations; tumor microenvironment

(This special issue belongs to the Section Biochemistry)

Current Research on Phenolic Profiles and Anti-Inflammatory Activities of Plants

edited by Chi-Rei Wu and Li-Wei Lin

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1150 | Submission Open

Keywords: plants; phenolic profiles; inflammation; cardiovascular disorders; cancer; diabetes; neurodegenerative disorders

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Cardiovascular and Metabolic Sequelae of Peripheral Artery Disease: From Mechanisms to Therapeutic Targets

edited by

Tzong-Shyuan Lee

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1117 | Submission Open

Keywords: peripheral artery disease (PAD); cardiometabolic complications; molecular mechanisms; endothelial dysfunction; interorgan crosstalk

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Host-Pathogen Interactions in Plants: Molecular Mechanisms and Sustainable Strategies

edited by Muhammad Rahil Afzal and Misbah Naz

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1112 | Submission Open

Keywords: plant immunity; plant–pathogen interactions; molecular mechanisms; effector biology; hormonal crosstalk; non-coding RNAs and epigenetics

(This special issue belongs to the Section Molecular Plant Sciences)

Nanoparticle–Protein Interactions: Therapeutic Approaches and Supramolecular Chemistry

edited by Rodrigo da Silva Ferreira

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1097 | Submission Open

Keywords: nanoparticle–protein interactions; nanomedicine; supramolecular chemistry; surface functionalization; protein corona; nanocarriers; biointerfaces; molecular recognition; therapeutic nanomaterials; computational nano–bio modelling

(This special issue belongs to the Section Molecular Nanoscience)

Advanced Silica-Based Materials: From Molecular Design to Sustainable Applications

edited by Marius Rǎdulescu

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1080 | Submission Open

Keywords: silica-based materials; molecular design; hybrid nanomaterials; surface chemistry; structure–property relationships; functionalized silica; sol–gel processes; molecular interactions; green synthesis; sustainable applications; nanostructured systems; catalysis and adsorption; biomedical interfaces; energy and environmental materials; molecular modeling

(This special issue belongs to the Section Molecular Nanoscience)

Advances in Polymeric Nanomaterials in Medicine

edited by Prabhanjan Giram

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1057 | Submission Open

Keywords: nanomaterials; nanocomposites; biomolecules; nano pharmaceuticals; nanoparticles; applications of nanomaterials; nanoformulation design; characterization; nanodrug delivery system; targeted and controlled release therapies

(This special issue belongs to the Section Molecular Nanoscience)

Extracellular Vesicles: Biomarkers and Therapeutic Carriers in Human Health and Disease

edited by

José Eduardo Vargas

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1051 | Submission Open

Keywords: extracellular vesicles; cellular senescence; autophagy; biomarkers; drug delivery; translational medicine; human disease; cell fate

(This special issue belongs to the Section Molecular Biology)

Chlorophylls and Carotenoids: Metabolism and Regulation in Plants

edited by

Shan Lu

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1028 | Submission Open

Keywords: chlorophyll; carotenoid; metabolism; regulation; evolution; coordination

(This special issue belongs to the Section Molecular Plant Sciences)

New Molecular Mechanisms and Markers in Inflammatory Disorders, 4th Edition

edited by

Elena Vianello

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1017 | Submission Open

Keywords: inflammation; inflammatory disorders; biomarkers; molecular mechanism of inflammation; molecular signaling

(This special issue belongs to the Section Molecular Immunology)

Non-Coding RNAs and Post-Transcriptional Modifications in Cancer

edited by

Christos K. Kontos

submission deadline 28 Feb 2027 | 1 articles | Viewed by 1012 | Submission Open

Keywords: solid tumors; hematological malignancies; long non-coding RNAs; circular RNAs; short non-coding RNAs

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Insights into Gangliosides

edited by

Sandro Sonnino

and

Massimo Aureli

submission deadline 28 Feb 2027 | 1 articles | Viewed by 987 | Submission Open

Keywords: gangliosides; sphingolipids; plasma membrane; lysosomes; glycohydrolases; neurodegeneration

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Advances in Oral and Periodontal Health

edited by

Giuseppina Malcangi

, Roxana Ioana Bordea and Grazia Marinelli

submission deadline 28 Feb 2027 | 1 articles | Viewed by 916 | Submission Open

Keywords: dental disease; dental materials; orthodontic diseases; growth factor; regenerative tissue; peritonitis; regulatory T cells; systemic disease; systemic inflammation; scaling and root planning

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Atlas of Cardiac Development and Diseases

edited by

Hector Alejandro Cabrera-Fuentes

submission deadline 28 Feb 2027 | 1 articles | Viewed by 883 | Submission Open

Keywords: cardiac development; molecular atlas; cardiovascular disease; single cell and spatial omics; multi omics integration; gene regulatory networks; cardiac remodeling; heart failure; systems biology; artificial intelligence in cardiology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Advances in Plant–Microbial Interaction

edited by

Diby Paul

submission deadline 28 Feb 2027 | 1 articles | Viewed by 882 | Submission Open

Keywords: plant microbe intractions; molecular mechanisms; microbiome dynamics; multi-omics approach; stress responses; metagenomics; rhizosphere signalling

(This special issue belongs to the Section Molecular Microbiology)

Recent Advances in Algal Stress Physiology

edited by

Zakaria Tazart

submission deadline 28 Feb 2027 | 1 articles | Viewed by 834 | Submission Open

Keywords: algae; microalgae; cyanobacteria; stress physiology; molecular mechanisms; signal transduction; gene regulation; redox homeostasis; omics technologies; environmental stress; metabolic adaptation; biotechnology

(This special issue belongs to the Section Molecular Plant Sciences)

Cellular Physiology and Aging: Membrane Dynamics, Intracellular Environment and Signaling Pathways

edited by

Alessia Remigante

Rossana Morabito

and Sara Spinelli

submission deadline 28 Feb 2027 | 1 articles | Viewed by 819 | Submission Open

Keywords: aging; oxidative stress; ion channels; antioxidant molecules; membrane transport systems; redox signaling; cellular senescence; inflammation; intracellular signaling pathways; mitochondrial dysfunction; bioactive compounds; cell physiology; homeostasis; longevity; age-related diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms of Hormone/Receptor System in Human Diseases

edited by Elena Zocchi,

Sonia Spinelli

and

Laura Sturla

submission deadline 28 Feb 2027 | 1 articles | Viewed by 818 | Submission Open

Keywords: hormone; receptor; energy metabolism; mitochondria

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Plant Metabolism and Genetics

edited by

Dalu Li

submission deadline 28 Feb 2027 | 1 articles | Viewed by 809 | Submission Open

Keywords: plant metabolism; genetics; genomics; multi-omics integration; secondary/specialized metabolites; biosynthetic pathways; metabolic engineering crop improvement

(This special issue belongs to the Section Molecular Plant Sciences)

Polyendocrine-Metabolic-Ovarian Syndrome: Targeted Therapeutics and Future Perspectives

edited by Noha Shawky and

Manar A. Eissa

submission deadline 28 Feb 2027 | 1 articles | Viewed by 807 | Submission Open

Keywords: PMOS; hyperandrogenism; insulin resistance; cardiometabolic disease; inflammation; maternal-offspring; developmental origins of health and disease; aging

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Latest Insight into Spin and Isomerism of Organic Molecules

edited by

Chenwei Jiang

and

Le Yu

submission deadline 28 Feb 2027 | 1 articles | Viewed by 781 | Submission Open

Keywords: organic molecules; photoisomerization; spin states; isomerism; spin crossover; conformational dynamics; quantum chemistry; radical chemistry; singlet fission

(This special issue belongs to the Section Molecular Biophysics)

Hepatocellular Carcinoma: From Pathophysiology to Innovative Therapeutic Approaches

edited by Andrea Martini

submission deadline 28 Feb 2027 | Viewed by 780 | Submission Open

Keywords: liver carcinogenesis; tumor microenvironment; immune surveillance; fibrogenesis; inflammation

(This special issue belongs to the Section Molecular Oncology)

Genetic and Molecular Strategies to Soybean Improvement

edited by

Junming Sun

submission deadline 28 Feb 2027 | 1 articles | Viewed by 769 | Submission Open

Keywords: soybean; genome editing; CRISPR/Cas9; quantitative trait loci (QTL); marker-assisted selection; functional genomics; molecular breeding; crop improvement; gene expression; genetics and breeding

(This special issue belongs to the Section Molecular Plant Sciences)

Advances in Allergen Immunotherapy: Current Concepts and Future Directions

edited by

Constantinos Pitsios

submission deadline 28 Feb 2027 | 1 articles | Viewed by 762 | Submission Open

Keywords: allergen immunotherapy; oral immunotherapy; Hymenoptera venom; allergy extracts; adjuvants

(This special issue belongs to the Section Molecular Immunology)

Displaying special issue 2551-2600 on page 52 of 63.

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