Molecular Mechanisms of Hormone/Receptor System in Human Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Endocrinology and Metabolism".
Deadline for manuscript submissions: 31 August 2026 | Viewed by 13
Special Issue Editors
Interests: obesity; dietary paterns; eating behaviors; metabolic syndrome
Interests: diabetes
Interests: glucose homeostasis; food supplement; abscisic acid; molecular mechanisms of signal transduction; insulin resistance; diabetes and related metabolic syndrome
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue is designed to provide readers with comprehensive and updated information on the latest developments on the molecular mechanisms underlying hormone/receptor system function and dysfunction in energy metabolism. The importance of this research area in human medicine is demonstrated by the multitude of research studies and reviews published just in the last year in indexed journals (>2000). Indeed, hormone/receptors systems lie at the heart of the regulation of every aspect of organ and organismic function. Knowledge of the molecular mechanisms underlying hormone/receptors physiology and dysfunction has allowed for the development of new drugs able to address diseased states as different from “canonical” endocrinological diseases such as cancer, reduced bone density, obesity, traumatic brain injury, cardiac arrhythmias, feeding behavior, and cognitive failure, among others.
This area of research entails studies focused on molecular (transcriptomics, metabolomics, proteomics), biochemical, physico-chemical, neurochemical and metabolic aspects of hormone/receptor function, including hormone/receptor interactions regulated by extracellular vesicle-mediated signals. We expect this issue to attract the interest of a wide readership, including specialists in endocrinology, neurosciences, internal medicine, and pharmacology, as well as researchers in other fields of human physiology who may want to be updated on the latest findings in this exciting field of research.
This Special Issue aims to present the most recent results in the rapidly expanding field of hormone/receptor function and dysfunction, with a particular focus on possible pharmacological interventions addressing the dysfunction. The study of dysmetabolic and obesity-related disorders has greatly profited from new information regarding the molecular pathways activated by new and already described signal molecules affecting cell and organismic energy metabolism. Interestingly, several of the hormone/receptor systems regulating energy metabolism and balance at an organismic level also impact on higher brain functions and cognitive abilities. The link between these apparently different effects appears to be control over mitochondrial performance.
In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following:
- Hormone/receptor(s) systems regulating mitochondrial energy metabolism;
- Biochemistry, molecular biology, physical–chemical studies, omics studies, and in vitro and in vivo; models of hormone/receptor function.
I/We look forward to receiving your contributions.
Prof. Dr. Elena Zocchi
Dr. Sonia Spinelli
Dr. Sturla Laura
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
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Keywords
- hormone
- receptor
- energy metabolism
- mitochondria
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