Antimicrobial and Antioxidant Properties of Bioactive Compounds from Foods

A special issue of Foods (ISSN 2304-8158). This special issue belongs to the section "Food Quality and Safety".

Deadline for manuscript submissions: 26 June 2026 | Viewed by 1381

Special Issue Editors


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Guest Editor
Institute of Food Technology in Novi Sad, University of Novi Sad, 21000 Novi Sad, Serbia
Interests: food and feed safety; antimicrobial, antifungal, and antibiofilm activities of natural bioactive compounds; development of innovative and eco-friendly strategies for controlling pathogens
Special Issues, Collections and Topics in MDPI journals

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Guest Editor Assistant
Institute of Food Technology in Novi Sad, University of Novi Sad, 21000 Novi Sad, Serbia
Interests: food and feed safety; antimicrobial properties of essential oils and plant extracts; natural and sustainable solutions for reducing antimicrobial drug use in veterinary and human medicine

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Guest Editor Assistant
Institute of Food Technology in Novi Sad, University of Novi Sad, 21000 Novi Sad, Serbia
Interests: insects as food and feed; bioactive peptides (antioxidative and antimicrobial activity); isolation and techno-functional properties of proteins

Special Issue Information

Dear Colleagues,

The growing demand for safe, high-quality, and minimally processed foods has intensified interest in natural bioactive compounds with antimicrobial and antioxidant properties. These compounds, derived from plant, animal, fungal, and microbial sources, support oxidative stability, inhibit pathogenic and spoilage microorganisms, and contribute to human health. Major classes include phenolics, flavonoids, carotenoids, peptides, polysaccharides, essential oils, and organic acids, all showing strong potential for use in food preservation and functional food development.

This Special Issue aims to present recent advances in the identification, characterization, and application of natural bioactive compounds in the food sector. Emphasis is placed on structure-activity relationships, synergistic interactions, and incorporation into innovative delivery systems such as nanoemulsions, edible coatings, and active packaging. Sustainable extraction and valorization of bioactive molecules from agricultural residues and food industry by-products, aligned with circular economy and zero-waste principles, are also encouraged.

Topics of interest include mechanisms of action against foodborne pathogens and oxidative stress, stabilization and encapsulation strategies, the influence of processing and storage on compound stability, novel analytical techniques, and health-promoting effects.

This Special Issue welcomes original research articles and comprehensive reviews aimed at advancing scientific knowledge and promoting nature-based solutions that enhance food safety, quality, and overall well-being for consumers.

Dr. Ivana Čabarkapa
Guest Editor

Dr. Dragana Tomanić
Dr. Danka Dragojlović
Guest Editor Assistants

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Foods is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • bioactive compounds
  • natural antimicrobials
  • antioxidants
  • food safety
  • nutraceuticals
  • food preservation
  • phytochemicals
  • polyphenols
  • essential oils
  • peptides
  • edible coatings
  • active packaging

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Published Papers (2 papers)

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Research

25 pages, 737 KB  
Article
Quality Evaluation and Multi-Criteria Optimization of Cookies Fortified with Lyophilized Black Goji
by Katarina Šavikin, Gordana Zdunić, Jelena Živković, Nada Ćujić Nikolić, Dejan Gođevac, Milica Nićetin, Jelena Filipović and Vladimir Filipović
Foods 2026, 15(10), 1733; https://doi.org/10.3390/foods15101733 - 14 May 2026
Viewed by 294
Abstract
Lyophilized black goji berry powder (LBGBP) cultivated in Serbia was evaluated and optimized as a fortification agent in cookie formulation. Nutritional, chemical, technical and biological characteristics, in vitro release and storage stability were analyzed. LBGBP is characterized by a phenolic-rich profile dominated by [...] Read more.
Lyophilized black goji berry powder (LBGBP) cultivated in Serbia was evaluated and optimized as a fortification agent in cookie formulation. Nutritional, chemical, technical and biological characteristics, in vitro release and storage stability were analyzed. LBGBP is characterized by a phenolic-rich profile dominated by acylated anthocyanins, 5-O-caffeoylquinic acid (5-O-CA), and spermidine-based phenylamides (S1, S2), which are partially retained in LBGBP-enriched cookies and enhance their functional properties. The substitution of different white flour shares with LBGBP in cookies statistically significantly improved their overall nutritional profile by increasing protein, dietary fiber, minerals and bioactive compounds, concurrently reducing fat, sugar and sodium levels. With the increase in the LBGBP in cookies, total phenolics and total anthocyanin content increased to the levels of 58.09 mg GAE/100 g and 10.12 mg CGE/100 g of cookies, respectively. The overall effect of LBGBP cookie fortification led to softer, more crumbly cookies with significant improvement in antioxidant and antidiabetic activity. The Z-score analysis was chosen to perform multi-criteria cookie formulation optimization with the goal of maximal functional enrichment, with minimal decrease in technological quality. The 10% LBGBP substitution was calculated to produce optimal overall quality, obtaining 65.96% of maximal score in comparison to the control sample of only 32.91%. Full article
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18 pages, 2324 KB  
Article
Enzyme-Modified Soy Protein/Maltodextrin Microcapsules Embedding Cinnamaldehyde: Structure, Release Characteristics, and Antibacterial Activity
by Guangxuan Shao, Zhao Li, Chao Yuan, Yunsong Jiang and Bo Cui
Foods 2026, 15(4), 714; https://doi.org/10.3390/foods15040714 - 14 Feb 2026
Viewed by 648
Abstract
Cinnamaldehyde (CIN) is a natural organic compound known for its antimicrobial and antioxidant properties. However, its susceptibility to environmental degradation has restricted its practical application. This study aimed to microencapsulate CIN using soy protein isolate hydrolysates and maltodextrin as wall materials through emulsion [...] Read more.
Cinnamaldehyde (CIN) is a natural organic compound known for its antimicrobial and antioxidant properties. However, its susceptibility to environmental degradation has restricted its practical application. This study aimed to microencapsulate CIN using soy protein isolate hydrolysates and maltodextrin as wall materials through emulsion preparation and spray drying, and to characterize the microstructure, controlled-release properties, antibacterial efficacy, and preservation performance of the resulting microcapsules. Under optimized condition, the encapsulation efficiency reached 70.72%. The microcapsules displayed smooth spherical structures, improved thermal stability, and an average particle size of 291.01 ± 33.64 nm. They demonstrated enhanced storage stability and sustained-release characteristics. Furthermore, the microcapsules exhibited significant antibacterial and antioxidant activity, which effectively delayed lipid and protein oxidation in pork loin for up to 6 days. Collectively, the results confirm the successful encapsulation of CIN and indicate the strong potential of these microcapsules for food industry applications requiring preservative and controlled-release functions. Full article
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