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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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AI-Driven Innovations in Medical Imaging and Diagnostics

edited by

Xiang Li

submission deadline 30 Sep 2026 | 1 articles | Viewed by 601 | Submission Open

Keywords: artificial intelligence; medical imaging; diagnosis; foundation models; generative AI; clinical decision support

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Feature Review Papers in Histopathology

edited by Dong Ren

submission deadline 30 Sep 2026 | Viewed by 582 | Submission Open

Keywords: histopathological features; histologic subtypes; diagnostic dilemma and pitfall; ancillary testing; tumor pathogenesis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Clinical Updates in Diagnosis and Management of Thrombocytopenia

edited by Maria Eva Mingot-Castellano and Cristina Pascual-Izquierdo

submission deadline 30 Sep 2026 | Viewed by 567 | Submission Open

Keywords: ITP; bleeding; thrombosis; anticoagulant; antiplatelet

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Recent Advances in Radiomics for Medical Imaging: Second Edition

edited by

Xiang Li

submission deadline 30 Sep 2026 | Viewed by 453 | Submission Open

Keywords: radiomics; PET/CT; SPECT/CT; medical imaging; cancers

(This special issue belongs to the Section Medical Imaging and Theranostics)

Integrative Computational Neuropathology: Multimodal Approaches for Precision Diagnosis

edited by Timothy E. van Meter

submission deadline 30 Sep 2026 | Viewed by 352 | Submission Open

Keywords: computational neuropathology; neurology; brain; spinal cord; multiplex; biomarkers; automated imaging; artificial intelligence; automated diagnosis; machine learning; precision medicine

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnostic Innovations in Metabolic Diseases Management

edited by

Teodora Alexescu

and Angela Cozma

submission deadline 30 Sep 2026 | Viewed by 332 | Submission Open

Keywords: metabolic diseases; cardio-reno-metabolic syndrome; obesity; metabolic syndrome

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Diagnostic Testing for Esophageal Diseases

edited by

Micheal Tadros

submission deadline 30 Sep 2026 | Viewed by 297 | Submission Open

Keywords: esophageal diseases; endoscopy; diagnostic tools; diagnostic testing; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Diagnostic Modalities for Benign Upper Gastrointestinal Disorders

edited by Gad Marom and Daniel Solomon

submission deadline 30 Sep 2026 | Viewed by 240 | Submission Open

Keywords: upper gastrointestinal tract; benign disorders; endoscopy; high resolution manometry; computerized tomography; barium swallow study; EndoFLIP

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advanced Electrocardiogram for Clinical Applications

edited by Francesco Luzza

submission deadline 30 Sep 2026 | Viewed by 227 | Submission Open

Keywords: cardiac electrophysiology; atrial fibrillation; arrhythmias; ventricular tachycardia; brugada pattern; QT interval; early repolarization; sudden cardiac death; myocardial ischemia; cardiomyopathies

(This special issue belongs to the Section Medical Imaging and Theranostics)

Sarcoidosis: Current Landscape and Future Developments

edited by

Ilias C. Papanikolaou

and Fotios Drakopanagiotakis

submission deadline 30 Sep 2026 | Viewed by 191 | Submission Open

Keywords: sarcoidosis; diagnosis; prognosis; biomarkers; imaging; histopathology; clinical presentation; diagnostic criteria; multidisciplinary approach; treatment; treatment algorithm

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Ocular Inflammation: Progress and Pitfalls in Diagnosis, Imaging and Management

edited by

Carl P. Herbort, Jr.

and

Ioannis Papasavvas

submission deadline 1 Oct 2026 | 2 articles | Viewed by 1728 | Submission Open

Keywords: uveitis; intraocular inflammation; fluorescein angiography (FA); indocyanine green angiography (ICGA); optical coherence tomography (OCT); enhanced depth imaging OCT (EDI-OCT); optical coherence tomography angiography (OCT-A); fundus autofluorescence (FAF); uveitis masquerades; intraocular interleukin assays; Vogt–Koyanagi–Harada disease (VKH); multiple evanescent white dot syndrome (MEWDS); consensus definitions

(This special issue belongs to the Section Medical Imaging and Theranostics)

AI for Precision Diagnostics: Enhancing Accuracy, Accessibility, and Outcomes

edited by

Shereen Afifi

and Mirza Mansoor Baig

submission deadline 30 Oct 2026 | 11 articles | Viewed by 8541 | Submission Open

Keywords: precision diagnostics; medical imaging and radiology; machine learning, deep learning, and transformers; biosensors and wearable health devices; explainable AI; point-of-care and remote diagnostic systems; digital health; edge AI and computing; bioinformatics; personalized medicine and health; healthcare accessibility

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Beyond the Joint: Advances in Musculoskeletal Imaging and Sports Radiology

edited by

Francesco Feletti

submission deadline 30 Oct 2026 | Viewed by 520 | Submission Open

Keywords: sports radiology; musculoskeletal imaging; diagnostic imaging; artificial intelligence; orthopaedics; extreme sports; outdoor sports; outdoor physical activity; one health; health policy

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in the Diagnosis and Treatment of Infections of the Central Nervous System

edited by

Teresa Perillo

and Raffaella Capasso

submission deadline 31 Oct 2026 | 2 articles | Viewed by 31381 | Submission Open

Keywords: central nervous system infections; meningitis; HIV; tuberculosis; magnetic resonance imaging

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Computed Tomography Imaging for Clinical Diagnosis—2nd Edition

edited by Ibrahim Yel

submission deadline 31 Oct 2026 | 8 articles | Viewed by 17373 | Submission Open

Keywords: computed tomography imaging; clinical diagnosis; dual-energy CT; photon-counting CT; image analysis

(This special issue belongs to the Section Medical Imaging and Theranostics)

Challenges in Monitoring and Diagnosis in Medical Sciences

edited by

Mihaela Badea

and

Laura Gaman

submission deadline 31 Oct 2026 | 5 articles | Viewed by 14847 | Submission Open

Keywords: diagnostic; monitoring; medical sciences

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Ovarian Cancer in 2025–2026: A Comprehensive Look at Characteristics, Screening, Diagnosis and Treatment

edited by

Edward J. Pavlik

submission deadline 31 Oct 2026 | 3 articles | Viewed by 9205 | Submission Open

Keywords: ovarian cancer; risk; treatment; detection; screening; trial design; treatment; collateral effects; endpoints; costs; efficacy; AI; sojourn time models; vaccines; PARP inhibitors; liquid biopsies; post treatment hematologic malignancies; HIPEC; STIC/STIL

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnosis and Prognosis of Abdominal Diseases

edited by

Filippo Carannante

submission deadline 31 Oct 2026 | 7 articles | Viewed by 8625 | Submission Open

Keywords: diagnosis; prognosis; abdominal diseases; markers; screening

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Updates in Vascular and Endovascular Surgery: Pathology, Diagnosis and Management

edited by Ombretta Martinelli and

Antonio Marzano

submission deadline 31 Oct 2026 | 7 articles | Viewed by 8427 | Submission Open

Keywords: aneurysms of the aorta; aneurysms of the arch; arterial stenosis; EVAR (endovascular aneurysm repair); FEVAR (fenestrated endovascular aneurysm repair); BEVAR (branched endovascular aneurysm repair); iliac branches; varicose veins; venous insufficiency; chronic obstructive arteriopathy

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Integrative Approaches in Head and Neck Cancer Imaging

edited by

Calin G. Buzea

submission deadline 31 Oct 2026 | 3 articles | Viewed by 7525 | Submission Open

Keywords: head and neck cancer; imaging technologies; multimodal imaging; image-guided therapy; artificial intelligence in imaging

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Machine Learning for Medical Image Processing and Analysis in 2026

edited by Wei Shao

submission deadline 31 Oct 2026 | 3 articles | Viewed by 7164 | Submission Open

Keywords: machine learning; medical image processing; diagnostic accuracy; healthcare; algorithms

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Pathology for Forensic Diagnosis

edited by

Cristina Mondello

and Vincenzo Cianci

submission deadline 31 Oct 2026 | 5 articles | Viewed by 6394 | Submission Open

Keywords: forensic pathology; forensic medicine; forensic radiology; forensic genetics; forensic toxicology; postmortem interval; forensic odontology; forensic entomology; forensic anthropology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnosis and Management of Liver Diseases, Third Edition

edited by

Jeong-Ju Yoo

submission deadline 31 Oct 2026 | 5 articles | Viewed by 6316 | Submission Open

Keywords: liver diseases; fatty liver; liver cirrhosis; viral hepatitis; hepatocellular carcinoma; diagnosis and management

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

New Insights into Gastrointestinal Endoscopy

edited by

Paraskevas Gkolfakis

and

Apostolis Papaefthymiou

submission deadline 31 Oct 2026 | 4 articles | Viewed by 6300 | Submission Open

Keywords: diagnosis; prognosis; gastrointestinal endoscopy; markers; clinical practice and patient care

(This special issue belongs to the Section Biomedical Optics)

Recent Advances in the Diagnosis and Prognosis of Lung Cancer

edited by Naomi Takemura

submission deadline 31 Oct 2026 | 4 articles | Viewed by 6238 | Submission Open

Keywords: lung cancer; molecular biomarkers; artificial intelligence; early detection; precision detection; medical imaging

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Clinical Diagnosis and Prognosis of Steatotic Liver Disease

edited by

Helma Pinchemel Cotrim

submission deadline 31 Oct 2026 | 4 articles | Viewed by 5481 | Submission Open

Keywords: steatotic liver disease—SLD; steatohepatitis; steatosis; diagnosis; prognosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnostic and Prognostic Non-Invasive Markers in Bladder Cancer

edited by

Qiang Lv

and Xiao Yang

submission deadline 31 Oct 2026 | 6 articles | Viewed by 5351 | Submission Open

Keywords: bladder cancer; diagnostic and prognostic markers; non-invasive; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advancements and Innovations in the Diagnosis of Lung Cancer

edited by

Houssein A. Youness

submission deadline 31 Oct 2026 | 4 articles | Viewed by 5014 | Submission Open

Keywords: lung cancer; diagnosis; biomarkers; artificial intelligence; robotic bronchoscopy; bronchoscopic imaging; endobronchial ultrasound; molecular profiling; genetic profiling; next-generation sequencing; tissue acquisition; low-dose CT screening; personalized medicine; medical imaging; lung nodules

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Optical Coherence Tomography in Non-Invasive Diagnostic Imaging

edited by

Carmen Cantisani

and

Sandra Schuh

submission deadline 31 Oct 2026 | 3 articles | Viewed by 4829 | Submission Open

Keywords: diagnosis; screening; marker; prognosis; optical coherence tomography; non-invasive diagnostic imaging

(This special issue belongs to the Section Biomedical Optics)

Advances in Oral Pathology of Basic and Clinical Cancer Research

edited by

Jun-Ichi Tanuma

submission deadline 31 Oct 2026 | 5 articles | Viewed by 4748 | Submission Open

Keywords: oral cancer; molecular pathology; tumor microenvironment (TME); immunotherapy; epigenetics; diagnosis; targeted therapy; personalized medicine; AI and image analysis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnostic Biomarkers of Urological Diseases

edited by

Martin Pejchinovski

and

Jochen Metzger

submission deadline 31 Oct 2026 | 1 articles | Viewed by 4476 | Submission Open

Keywords: proteomics; biomarkers; diagnosis; prediction; treatment; clinical application; technical advances

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnostic Progress in Gynecologic Oncology

edited by

Antoni Llueca

submission deadline 31 Oct 2026 | 4 articles | Viewed by 4293 | Submission Open

Keywords: gynecologic oncology; early diagnosis; molecular diagnostics; imaging techniques; artificial intelligence; biomarkers; cervical cancer; endometrial cancer; ovarian cancer; personalized medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Precision Medicine for Cerebellar Disorders: From Bench to Bedside

edited by Mario Manto and

Hiroshi Mitoma

submission deadline 31 Oct 2026 | Viewed by 4256 | Submission Open

Keywords: cerebellum; cerebellar disorders; ataxia/cerebellar ataxia; preclinical research; precision medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Novel Optical Imaging Technologies in Ophthalmology and Neuroscience: Advances and Applications

edited by

Jae-Ho Han

submission deadline 31 Oct 2026 | 4 articles | Viewed by 4206 | Submission Open

Keywords: optical imaging; ophthalmology; neuroscience; diagnosis; prognosis

(This special issue belongs to the Section Biomedical Optics)

Clinical Diagnosis and Management in Emergency and Hospital Medicine–2nd Edition

edited by

Nin-Chieh Hsu

submission deadline 31 Oct 2026 | 1 articles | Viewed by 3871 | Submission Open

Keywords: diagnosis; treatment; management; hospital medicine; emergency medicine; point-of-care ultrasound; decision making; transitional care; palliative care; quality improvement

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Clinical and Biochemical Diagnosis and Management of Obesity

edited by

Iwona Beń-Skowronek

submission deadline 31 Oct 2026 | 5 articles | Viewed by 3563 | Submission Open

Keywords: obesity; biomarker; body composition; metabolic assessment; multidisciplinary management; bariatric surgery

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Cardiovascular Diseases: Advances in Echocardiography and Cardiac Computed Tomography

edited by Vasileios Kamperidis

submission deadline 31 Oct 2026 | 2 articles | Viewed by 3429 | Submission Open

Keywords: heart failure; echocardiography; valvular heart disease; strain imaging; cardiac computed tomography; atherosclerosis; cardiomyopathy; 3D imaging; coronary artery disease; CT FFR; perfusion imaging; stress echocardiography; TEE

(This special issue belongs to the Section Medical Imaging and Theranostics)

Clinical Diagnostics and Management of Stroke

edited by

Qiwen Deng

submission deadline 31 Oct 2026 | 3 articles | Viewed by 3407 | Submission Open

Keywords: ischemic stroke; diagnostic; thrombolysis; endovascular thrombectomy; post-stroke cognitive impairment; secondary prevention; neuroinflammation; neuroprotection

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Recent Advances in Maternal–Fetal Medicine

edited by Roxana Elena Bohiltea

submission deadline 31 Oct 2026 | 1 articles | Viewed by 3067 | Submission Open

Keywords: maternal–fetal medicine; pregnancy; prenatal care

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Clinical Diagnosis and Management of Metabolic Bone Diseases

edited by

Maria Lucia Fleiuss Farias

submission deadline 31 Oct 2026 | 1 articles | Viewed by 2967 | Submission Open

Keywords: bone; PTH; hyperparathyroidism; chronic kidney disease-metabolic bone disorder; osteoporosis; DXA; HR-pQCT

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Management of Diabetes Mellitus

edited by

Franklyn Iheagwam

and

Tar-Choon Aw

submission deadline 31 Oct 2026 | 3 articles | Viewed by 2963 | Submission Open

Keywords: diabetes diagnosis; glycemic monitoring; personalized treatment; chronic complications; point-of-care testing; insulin resistance; diagnostic biomarkers

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

New Developments in the Diagnosis of Skin Tumors: 2nd Edition

edited by

Sorina Danescu

submission deadline 31 Oct 2026 | Viewed by 2961 | Submission Open

Keywords: basal cell carcinoma; melanoma; benign tumors; cutaneous squamous cell carcinoma; Bowen’s disease; actinic keratosis; diagnosis; biomarkers; imaging techniques; molecular diagnostics; histopathology; precision medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

The Future of Diagnostics: Exploring the Role of Artificial Intelligence in Medicine 2026

edited by

Shang-Ming Zhou

, Neil Vaughan and Jiaxiang Zhang

submission deadline 31 Oct 2026 | 1 articles | Viewed by 2485 | Submission Open

Keywords: diagnostics; artificial intelligence; medicine; healthcare; future

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Emerging Insights in Dental Diagnostics, Biomaterials and Digital Workflow

edited by

Marina Meleșcanu Imre

and

Ana Maria Cristina Țâncu

submission deadline 31 Oct 2026 | 2 articles | Viewed by 2408 | Submission Open

Keywords: dental diagnostics; artificial intelligence (AI); digital dentistry; biomaterials; 3D printing; intraoral scanning; CAD/CAM; digital workflow; predictive analytics; clinical innovation

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Laboratory Medicine—from Research to Clinical Implementation

edited by Kelvin Y. K. Chan and Sergio Bernardini

submission deadline 31 Oct 2026 | Viewed by 2404 | Submission Open

Keywords: laboratory medicine; clinical practice; laboratory diagnosis; artificial intelligence

(This special issue belongs to the Section Clinical Laboratory Medicine)

Advanced Imaging for Diagnosis and Management of Musculoskeletal Disorders

edited by

Takeshi Fukuda

submission deadline 31 Oct 2026 | 5 articles | Viewed by 2346 | Submission Open

Keywords: musculoskeletal imaging; magnetic resonance imaging (MRI); computed tomography (CT); photon-counting CT; advanced imaging techniques; quantitative imaging; inflammatory arthritis; trauma; sports-related disorders

(This special issue belongs to the Section Medical Imaging and Theranostics)

Hematology: Diagnostic Techniques and Assays, 2nd Edition

edited by Chihyun Cho

submission deadline 31 Oct 2026 | 3 articles | Viewed by 2330 | Submission Open

Keywords: diagnostic; hematology; technique; assay; biomarkers

(This special issue belongs to the Section Clinical Laboratory Medicine)

Advances in Pediatric Ophthalmology Diagnostics and Management

edited by Mariola Dorecka and Bogumiła Wójcik-Niklewska

submission deadline 31 Oct 2026 | 2 articles | Viewed by 2205 | Submission Open

Keywords: pediatric ophthalmology; children; congenital glaucoma; congenital cataract; cornea; strabismus; myopia; retinopathy of prematurity; amblyopia

(This special issue belongs to the Section Biomedical Optics)

Neurological Diseases: Novel Biomarkers for Diagnosis and Management

edited by

Costanza Maria Cristiani

submission deadline 31 Oct 2026 | 1 articles | Viewed by 2148 | Submission Open

Keywords: biomarkers; laboratory medicine; neuroimaging; neurological diseases; treatment; management; clinical diagnostics

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Management of Meningitis—2nd Edition

edited by

Georgina Tzanakaki

submission deadline 31 Oct 2026 | 1 articles | Viewed by 2017 | Submission Open

Keywords: bacterial meningitis; invasive meningococcal disease; molecular diagnostics; molecular typing; laboratory surveillance; molecular epidemiology

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Displaying special issue 151-200 on page 4 of 13.

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