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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Diagnostic Advances in Obstetrics and Gynecology, Breast Disease and Women’s Health

edited by Menelaos Zafrakas

submission deadline 30 Nov 2026 | 5 articles | Viewed by 14702 | Submission Open

Keywords: obstetrics; gynecology; maternal– fetal medicine; breast; women’ s health; diagnostics

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Application of Artificial Intelligence to Advance Individualized Diagnosis and Treatment in Emergency and Critical Care Medicine, 2nd Edition

edited by

Zhongheng Zhang

submission deadline 30 Nov 2026 | 6 articles | Viewed by 10282 | Submission Open

Keywords: critical care; sepsis; artificial intelligence; predictive analytics; clustering; acute kidney injury; emergency medicine; transcriptome

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Diagnostics of Chronic Kidney Disease

edited by

Tomasz Gołębiowski

and

Andrzej Konieczny

submission deadline 30 Nov 2026 | 5 articles | Viewed by 9905 | Submission Open

Keywords: chronic kidney disease; diabetic nephropathy; glomerulonephritis; acid– base disorders; uremic toxin; artificial intelligence; metabolic bone disease; vascular access; arteriovenous fistula; catheter; hemodialysis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnosis, Treatment, and Prognosis of Breast Cancer

edited by

Marko Buta

submission deadline 30 Nov 2026 | 6 articles | Viewed by 8448 | Submission Open

Keywords: breast cancer diagnosis; molecular profiling; artificial intelligence; targeted therapy; immunotherapy; treatment strategies; prognostic markers; triple-negative breast cancer

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Diagnosis of Skin and Superficial Tissues Disorders—“Old and Emerging” Diagnostic Tools—2nd Edition

edited by Costantino Ricci

submission deadline 30 Nov 2026 | 5 articles | Viewed by 8411 | Submission Open

Keywords: melanoma; melanocytic pathology; Merkel cell carcinoma; adnexal tumors; anatomy of the skin; histology of the skin; molecular pathology; next-generation sequencing; immunohistochemistry; histology-sonography correlation; high-frequency ultrasound probes and high-level ultrasound machines; line-field confocal optical coherence tomography

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Periodontal and Other Associated Oral Diseases: Diagnosis and Management in the Context of Systemic Pathology, 2nd Edition

edited by

Silvia Martu

Liliana-Georgeta Foia

and

Maria Alexandra Mârțu

submission deadline 30 Nov 2026 | 2 articles | Viewed by 6853 | Submission Open

Keywords: periodontitis; oral diseases; periimplantitis; biomarkers; cytokines; oxidative stress markers; PCR test; point-of-care test; CBCT; periodontal treatment; immunomodulatory therapy; local drug delivery

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Alzheimer's Disease Diagnosis Based on Deep Learning

edited by Anees Abrol

submission deadline 30 Nov 2026 | 3 articles | Viewed by 6796 | Submission Open

Keywords: Alzheimer's disease (AD); deep learning; MRI; demographic information; disease probability map; convolutional neural network (CNN)

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Point-of-Care Testing (POCT) for Infectious Diseases

edited by Rongzhang Hao

submission deadline 30 Nov 2026 | 4 articles | Viewed by 5680 | Submission Open

Keywords: point-of-care testing (POCT); microfluidic chip and biosensor; ultrafast detection techniques; AI-integrated testing systems; infectious disease; pathogen

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Opportunities in Laboratory Medicine in the Era of Genetic Testing

edited by

Fernanda De-Paris

submission deadline 30 Nov 2026 | 5 articles | Viewed by 5340 | Submission Open

Keywords: laboratory medicine; genetic testing; molecular diagnostics; personalized medicine; clinical decision-making; infectious disease diagnosis; precision oncology

(This special issue belongs to the Section Clinical Laboratory Medicine)

Diagnosis and Management of Vascular Diseases

edited by Tiffany R. Bellomo and Abhisekh A. Mohapatra

submission deadline 30 Nov 2026 | 3 articles | Viewed by 4705 | Submission Open

Keywords: diagnosis; management; vascular diseases; marker; non-invasive imaging

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Management of Dental Medicine and Surgery, 2nd Edition

edited by

José María Martínez González

submission deadline 30 Nov 2026 | 3 articles | Viewed by 3905 | Submission Open

Keywords: oral surgery; oral medicine; implant dentistry; gerontology; bone regeneration; oral rehabilitation

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Artificial Intelligence in Medical Imaging: Innovations and Diagnostic Applications

edited by

Ayman El-Baz

, Moumen Elmelegy,

Asem M. Ali

and

Ali H. Mahmoud

submission deadline 30 Nov 2026 | 3 articles | Viewed by 3415 | Submission Open

Keywords: medical imaging; artificial intelligence; disease diagnosis; radiomics

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Artificial Intelligence in Magnetic Resonance Imaging

edited by

Aydin Eresen

submission deadline 30 Nov 2026 | 3 articles | Viewed by 3086 | Submission Open

Keywords: magnetic resonance imaging; artificial intelligence; diagnostic medicine; MRI data analysis; image processing

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Diagnostic Radiology in Head and Neck Diseases

edited by

Daniel Ginat

submission deadline 30 Nov 2026 | 2 articles | Viewed by 2890 | Submission Open

Keywords: head ; neck ; imaging ; radiology ; magnetic resonance imaging ; computed tomography

(This special issue belongs to the Section Medical Imaging and Theranostics)

AI for Medical Diagnosis: From Algorithms to Clinical Integration

edited by

Hyun-Soo Choi

submission deadline 30 Nov 2026 | 5 articles | Viewed by 2579 | Submission Open

Keywords: novel neural architectures; explainable and trustworthy AI (XAI); medical foundation models; algorithmic robustness and generalization; multimodal data integration; data-efficient learning (few-shot/self-supervised); clinical decision support systems (CDSSs); real-time diagnostic algorithms; edge AI for medical devices

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Transforming Cancer Care Through Molecular Diagnostics and Biomarker Discovery

edited by

Babak Behnam

submission deadline 30 Nov 2026 | Viewed by 2033 | Submission Open

Keywords: molecular diagnostics; cancer biomarkers; precision oncology; liquid biopsy; genomic profiling; clinical translation; early detection; therapeutic monitoring; multi-omic analysis; next-generation sequencing

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Artificial Intelligence in Biomedical Image Analysis 2026

edited by

Jasjit S. Suri

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1988 | Submission Open

Keywords: artificial intelligence; biomedical image analysis; diagnosis; cancer; neurological disorders

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in the Application of Ultrasound Technology in the Diagnosis of Skin Diseases

edited by

Priscila Giavedoni

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1860 | Submission Open

Keywords: skin ultrasound; cutaneous imaging; inflammatory skin diseases; skin tumors; high-frequency ultrasound; diagnostic imaging; medical imaging; ultrasound-guided procedures; dermatology; skin assessment

(This special issue belongs to the Section Medical Imaging and Theranostics)

Innovations in Kidney Disease Diagnostics: Organoids, Pathology, and Clinical Insights

edited by

Kenji Tsuji

submission deadline 30 Nov 2026 | Viewed by 1848 | Submission Open

Keywords: chronic kidney disease; diabetic kidney disease; glomerulonephritis; polycystic kidney diseases; renal pathology; biomarker; kidney regeneration; hemodialysis; peritoneal dialysis; diagnosis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Genomics in Cardiac Diagnostics: Bridging Novel Insights to Clinical Practice

edited by

Yiqing Yang

submission deadline 30 Nov 2026 | 2 articles | Viewed by 1811 | Submission Open

Keywords: cardiovascular disease; congenital heart disease; cardiac arrhythmia; idiopathic cardiomyopathy; coronary heart disease; arterial hypertension; stroke; genetics; genomics

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Global Advances in EGD and Colonoscopy: The Convergence of Advanced Imaging and AI

edited by

Naohisa Yoshida

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1704 | Submission Open

Keywords: esophagogastroduodenoscopy (EGD); colonoscopy; artificial intelligence; image-enhanced endoscopy; optical biopsy

(This special issue belongs to the Section Biomedical Optics)

Innovative Research and Operational Advances in the Diagnosis of Hematologic Diseases

edited by

Robert S. Ohgami

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1596 | Submission Open

Keywords: hematologic diseases; genomic diagnostics; digital pathology; biomarker; laboratory diagnostics

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnosis and Management of Lung Diseases

edited by

Fu-Zong Wu

and

Nevenka Piskac Zivkovic

submission deadline 30 Nov 2026 | 2 articles | Viewed by 1355 | Submission Open

Keywords: endobronchial ultrasound; navigational bronchoscopy; robotic bronchoscopy; cryobiopsy; lung cancer; interstitial lung diseases; OMICS approaches; proteomics; emphysema; chronic obstructive pulmonary disease

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnostics and Management of Sarcopenia, Frailty, and Aging

edited by Jong Geol Do

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1315 | Submission Open

Keywords: sarcopenia; frailty; aging; geriatric; rehabilitation; biomarkers; digital health

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Risk Factors, Incidence, and Outcome of Stroke

edited by Emir Veledar

submission deadline 30 Nov 2026 | 3 articles | Viewed by 1293 | Submission Open

Keywords: stroke prevention; acute stroke management; post-acute stroke care; predictive modeling; risk stratification; neuroimaging; biomarkers; early detection; prognostic evaluation; diagnostic algorithms; cerebral infarction; intracranial hemorrhage; ischemic stroke subtypes

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Current Issues in Kidney Diseases Diagnosis and Management 2026

edited by

Luis Yu

submission deadline 30 Nov 2026 | 3 articles | Viewed by 1171 | Submission Open

Keywords: kidney diseases; renal involvement; AKI; CKD; glomerulopathies; diagnosis; treatment; dialysis; epidemiology; nephritic syndrome; nephrotic syndrome; biomarkers; urinalysis; oliguria; polyuria; electrolytes; acid– base balance

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Insights into Gastrointestinal Pathology

edited by Gautam Mankaney

submission deadline 30 Nov 2026 | 2 articles | Viewed by 1143 | Submission Open

Keywords: colorectal cancer; genetic screening; gastroenterology; biomarkers

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in the Diagnosis and Management of Low-Back Pain

edited by

Raffaele Natella

Federico Bruno

and Daniele Giuseppe Romano

submission deadline 30 Nov 2026 | 2 articles | Viewed by 1099 | Submission Open

Keywords: low back pain; magnetic resonance imaging; radiculopathy; imaging biomarkers; patient selection; interventional radiology; epidural injections; radiofrequency ablation; intradiscal therapy; vertebral augmentation

(This special issue belongs to the Section Medical Imaging and Theranostics)

Next-Generation Imaging and AI in Structural Heart Disease: From Detection to Risk Stratification and Prognosis

edited by

Mao Chen

submission deadline 30 Nov 2026 | Viewed by 1082 | Submission Open

Keywords: structural heart disease; artificial intelligence; diagnostic test; risk stratification; image innovation; deep learning

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Interdisciplinary Approaches to Musculoskeletal Disorders: From Imaging to Management

edited by

Ralf Henkelmann

and Jeanette Henkelmann

submission deadline 30 Nov 2026 | 2 articles | Viewed by 1063 | Submission Open

Keywords: musculoskeletal imaging; interdisciplinary management; clinical decision-making; quantitative imaging; imaging biomarkers; alignment and positioning; artificial intelligence; surgical planning

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Thrombosis Diagnosis and Antithrombotic Therapy

edited by Ovidio De Filippo,

Fabrizio D’Ascenzo

and Francesco Antonio Veneziano

submission deadline 30 Nov 2026 | 1 articles | Viewed by 980 | Submission Open

Keywords: antithrombotic therapy; ischemic heart disease; risk stratification; personalized medicine; dual antiplatelet therapy; bleeding risk; coronary artery disease; artificial intelligence

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Neurological Diseases: Biomarkers, Diagnosis and Prognosis, 2nd Edition

edited by

Theodosis Kalamatianos

submission deadline 30 Nov 2026 | 2 articles | Viewed by 956 | Submission Open

Keywords: biomarkers; neurological diseases; multiple sclerosis; traumatic brain injury; peripheral neuropathies; COVID-19 neurological-associated damage; diagnosis; prognosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Pediatric Diseases: From Diagnosis to Management

edited by

Adrijan Sarajlija

submission deadline 30 Nov 2026 | 2 articles | Viewed by 906 | Submission Open

Keywords: pediatric diseases; diagnosis; management; translational research; rare and complex disorders; precision medicine; molecular diagnostics; interdisciplinary care

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Diagnosis of Gynecological Cancers: 2nd Edition

edited by

Angela Santoro

and

Gian Franco Zannoni

submission deadline 30 Nov 2026 | 1 articles | Viewed by 817 | Submission Open

Keywords: gynecological cancers; histopathology; next-generation sequencing; liquid biopsy; theranostics; digital pathology; artificial intelligence and machine learning

(This special issue belongs to the Section Medical Imaging and Theranostics)

Latest Advances in Ophthalmic Imaging: Second Edition

edited by

Slawomir Teper

and

Gawęcki Maciej

submission deadline 30 Nov 2026 | 1 articles | Viewed by 805 | Submission Open

Keywords: optical coherence tomography (OCT); adaptive optics imaging; fundus photography; multimodal imaging; artificial intelligence (AI) in ophthalmic imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Molecular Pathology and Biomarkers for Tumor Diagnosis and Prognosis

edited by

Maurizio Martini

and

Gabriele Ricciardi

submission deadline 30 Nov 2026 | 1 articles | Viewed by 746 | Submission Open

Keywords: molecular pathology; biomarkers; modern oncology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Novel Advances in the Diagnosis of Dermatology

edited by

Federico Venturi

submission deadline 30 Nov 2026 | 1 articles | Viewed by 716 | Submission Open

Keywords: artificial intelligence in dermatology; dermoscopy; reflectance confocal microscopy; optical coherence tomography; line-field confocal optical coherence tomography (LC-OCT); skin cancer diagnosis; molecular biomarkers; digital dermatology; non-invasive imaging; precision dermatology

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

New Radiological, Electrocardiographic and Biochemical Cardiovascular Risk Factors in 2026

edited by

Paweł Gać

submission deadline 30 Nov 2026 | 1 articles | Viewed by 703 | Submission Open

Keywords: cardiovascular medicine; risk factors; heart and vascular biology; imaging diagnostics; electrocardiogram; biochemistry; toxicology; experimental medicine

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Image Quality Assessment Methods in Radiography, Computed Tomography and Magnetic Resonance—2nd Edition

edited by

Maciej Krupiński

and

Adam Piórkowski

submission deadline 30 Nov 2026 | 1 articles | Viewed by 664 | Submission Open

Keywords: CR; MRI; CT; image quality; preprocessing and postprocessing; texture analysis; quality control

(This special issue belongs to the Section Medical Imaging and Theranostics)

Artificial Intelligence in Hearing Diseases

edited by

Mehdi Abouzari

submission deadline 30 Nov 2026 | Viewed by 394 | Submission Open

Keywords: artificial intelligence; hearing loss; diagnosis; machine learning; auditory neuroscience; speech recognition; cochlear implants; data science; computational algorithm

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in the Diagnosis of Oral and Maxillofacial Disease: Third Edition

edited by

Luís Eduardo Almeida

submission deadline 30 Nov 2026 | 1 articles | Viewed by 382 | Submission Open

Keywords: maxillofacial disease; oral disease; biomarkers; prognosis; periodontal disease; machine learning; MRI; CBCT

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in the Diagnosis and Management of Musculoskeletal Tumors

edited by

Tomoki Nakamura

submission deadline 30 Nov 2026 | Viewed by 341 | Submission Open

Keywords: bone tumors; soft tissue tumors; metastatic bone tumors; diagnosis; chemotherapy; immunotherapy

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnosis and Management in Otolaryngology, 2nd Edition

edited by

Rong-San Jiang

submission deadline 30 Nov 2026 | 1 articles | Viewed by 339 | Submission Open

Keywords: ear; diagnosis; head and neck; management; nose; otolaryngology; throat

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Large Vision–Language Models (LVLMs) in Medical Imaging: Methods, Evaluation, and Clinical Translation

edited by

Tim Duong

submission deadline 30 Nov 2026 | Viewed by 274 | Submission Open

Keywords: large vision– language models (LVLMs); medical imaging; diagnostics; AI; radiology and pathology

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Imaging-Driven Virtual and Augmented Reality for Surgical Diagnosis and Intervention

edited by

Maki Sugimoto

submission deadline 30 Nov 2026 | Viewed by 267 | Submission Open

Keywords: imaging; three-dimensional reconstruction; virtual; augmented; mixed; extended reality; hologram; polygon modeling; spatial computing; image guided; surgical diagnosis; minimally invasive surgery; endoscopic surgery; robot; MRI; CT; ultrasound

(This special issue belongs to the Section Medical Imaging and Theranostics)

Wearable Sensors and Artificial Intelligence for Real-Time Disease Monitoring

edited by

Wei-Chih Lien

submission deadline 30 Nov 2026 | Viewed by 264 | Submission Open

Keywords: wearable sensors; artificial intelligence; real-time monitoring; digital health; biosensors; machine learning

(This special issue belongs to the Section Point-of-Care Diagnostics and Devices)

New Advances in Artificial Intelligence for Clinical Diagnostic Decision Making

edited by

Md Mohaimenul Islam

and

Ming-Chin Lin

submission deadline 30 Nov 2026 | Viewed by 259 | Submission Open

Keywords: artificial intelligence; machine learning; clinical decision support systems; health disparity; medical imaging; disease diagnosis; medical errors; patient safety

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Techniques and Applications in Forensic Medicine: From Clinical to Pathology

edited by

Angelo Montana

submission deadline 30 Nov 2026 | Viewed by 220 | Submission Open

Keywords: forensic medicine; clinical forensic medicine; forensic pathology; autopsy; DNA analysis; trauma; forensic imaging; post-mortem radiology; toxicology; cause of death

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Innovations in Diagnosis and Clinical Practice of Corneal Disorders

edited by Lei Tian

submission deadline 30 Nov 2026 | Viewed by 206 | Submission Open

Keywords: corneal diseases; corneal biomechanics; diagnostic innovation; in vivo corneal imaging; ocular biomarkers; artificial intelligence in ophthalmology; clinical ophthalmology

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Breast Imaging: Improving Detection and Diagnosis

edited by

Graziella Di Grezia

submission deadline 30 Nov 2026 | Viewed by 203 | Submission Open

Keywords: breast cancer screening; digital breast tomosynthesis (DBT); contrast-enhanced mammography (CEM); breast MRI; artificial intelligence; radiomics; automated breast ultrasound (ABUS)

(This special issue belongs to the Section Medical Imaging and Theranostics)

Displaying special issue 401-450 on page 9 of 13.

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