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Diagnostics
Special Issues
New Radiological, Electrocardiographic and Biochemical Cardiovascular Risk Factors in 2026
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New Radiological, Electrocardiographic and Biochemical Cardiovascular Risk Factors in 2026

A Special Issue of Diagnostics (ISSN 2075-4418) belonging to the section "Clinical Diagnosis and Prognosis".

Deadline for manuscript submissions: 30 November 2026 | Viewed by 1440

Editor

Dr. Paweł Gać

E-Mail Website
Guest Editor
1. Department of Environmental Health, Occupational Medicine and Epidemiology, Wroclaw Medical University, Mikulicza-Radeckiego 7, 50-345 Wroclaw, Poland
2. Centre of Diagnostic Imaging, 4th Military Hospital, Weigla 5, 50-981 Wroclaw, Poland
Interests: imaging diagnostics; environmental health; occupational medicine; cardiovascular system; cardiovascular prevention; risk factors and pathophysiology of cardiovascular diseases; hypertension; sleep disturbance
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Cardiovascular diseases are the leading cause of death worldwide. According to the latest statistics on the structure of deaths in the world, in 2016, cardiovascular diseases were the main cause of death (34.2% of all recorded deaths). Moreover, diseases of the cardiovascular system are characterized by a rapid increase in epidemiological importance, practically since the 1950s, which partially stopped at the turn of the 20th and 21st centuries.

Radiology and imaging diagnostics, electrophysiology and biochemistry are currently recognized diagnostic methods for cardiovascular diseases. They have gained a further increase in clinical importance in recent years. It is already impossible to imagine modern medicine without the aforementioned diagnostic methods, and the perspective for the next few years will only strengthen this tendency.

We invite you to publish original articles and review papers on the significance and predictive value of new radiological, electrocardiographic and biochemical risk factors for cardiovascular diseases.

Dr. Paweł Gać
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cardiovascular medicine
  • risk factors
  • heart and vascular biology
  • imaging diagnostics
  • electrocardiogram
  • biochemistry
  • toxicology
  • experimental medicine

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Related Special Issue

Published Papers (2 papers)

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Research

13 pages, 916 KB  
Article
Comparative Analysis of Lipid Indices in Predicting Residual SYNTAX Score After Primary PCI in Patients with Acute Coronary Syndrome
by İsmail Ünğan and Ramazan Asoğlu
Diagnostics 2026, 16(15), 2412; https://doi.org/10.3390/diagnostics16152412 - 31 Jul 2026
Viewed by 372
Abstract
Background: Atherosclerotic cardiovascular disease remains the leading cause of ischemic heart disease, with dyslipidemia representing one of its principal modifiable risk factors. This study sought to evaluate the association between residual coronary artery disease burden and contemporary lipid indices in patients presenting with [...] Read more.
Background: Atherosclerotic cardiovascular disease remains the leading cause of ischemic heart disease, with dyslipidemia representing one of its principal modifiable risk factors. This study sought to evaluate the association between residual coronary artery disease burden and contemporary lipid indices in patients presenting with a first episode of acute coronary syndrome. Methods: A total of 317 patients were retrospectively evaluated between January 2022 and June 2023. Demographic features, comorbid conditions, laboratory measurements, conventional lipid parameters, contemporary lipid ratios, SYNTAX scores (SS), and residual SYNTAX scores (rSS) were recorded. Following primary percutaneous coronary intervention (PCI), patients were categorized by residual SYNTAX score (rSS) as rSS-negative (score = 0) or rSS-positive (score ≥ 1). Results: Of the 317 patients, 174 had an rSS > 0, with a median rSS of 6 (IQR, 3–10). Patients with rSS > 0 had lower HDL-C and higher LDL-C/HDL-C and non-HDL-C/HDL-C ratios than those with rSS = 0. In adjusted models, HDL-C was inversely associated with rSS positivity (OR per 1-mg/dL increase, 0.965; 95% CI, 0.932–0.999), whereas the LDL-C/HDL-C ratio (OR per 1-unit increase, 1.337; 95% CI, 1.021–1.752) and the non-HDL-C/HDL-C ratio (OR per 1-unit increase, 1.257; 95% CI, 1.017–1.553) were positively associated. Baseline SYNTAX score was the dominant predictor, and none of the lipid-extended models significantly improved discrimination over the reference model. Conclusions: HDL-C, the LDL-C/HDL-C ratio, and the non-HDL-C/HDL-C ratio were independently associated with residual SYNTAX score positivity following primary PCI in patients presenting with a first ACS. These routinely available lipid indices may provide complementary information regarding the presence of residual coronary disease in this specific patient population. Full article
(This article belongs to the Special Issue New Radiological, Electrocardiographic and Biochemical Cardiovascular Risk Factors in 2026)
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16 pages, 693 KB  
Article
Ultrasound-Assessed Brachial Artery Flow-Mediated Dilation and Carotid Plaque Burden as Markers of Vascular Health in Relation to Weekly Physical Activity Duration in Older Adults
by Michał Fułek, Tomasz Harych, Piotr Macek, Katarzyna Fułek, Krzysztof Kraik, Barbara Dziadkowiec-Macek, Jarosław Domaradzki, Małgorzata Poręba, Andrzej Wysocki, Paweł Gać and Rafał Poręba
Diagnostics 2026, 16(8), 1229; https://doi.org/10.3390/diagnostics16081229 - 20 Apr 2026
Cited by 1 | Viewed by 621
Abstract
Objectives: This study assessed the association between physical activity and vascular endothelial function and carotid atherosclerotic plaques in older adults using ultrasound imaging. Methods and Results: A total of 60 older adults were divided into three groups based on weekly physical [...] Read more.
Objectives: This study assessed the association between physical activity and vascular endothelial function and carotid atherosclerotic plaques in older adults using ultrasound imaging. Methods and Results: A total of 60 older adults were divided into three groups based on weekly physical activity: low (<4 h/week), moderate (4–12 h/week), and high (>12 h/week). All participants underwent flow-mediated dilation (FMD) assessment and carotid ultrasound to determine plaque burden. Participants with moderate physical activity demonstrated greater FMD (12.3 ± 2.5%) than those with low (1.2 ± 1.8%) or high activity (7.1 ± 1.3%), and a lower carotid plaque burden. In adjusted logistic regression models, moderate activity remained independently associated with a lower likelihood of impaired FMD (OR 0.22; 95% CI 0.18–0.27) and lower carotid plaque burden (OR 0.16; 95% CI 0.11–0.19). Conclusions: Moderate physical activity was associated with more favorable vascular endothelial function and reduced carotid atherosclerosis in older adults, indicating an association with a more favorable vascular profile. Full article
(This article belongs to the Special Issue New Radiological, Electrocardiographic and Biochemical Cardiovascular Risk Factors in 2026)
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