Diagnosis and Management of Lung Diseases
A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Clinical Diagnosis and Prognosis".
Deadline for manuscript submissions: 30 November 2026 | Viewed by 1756
Editors
2. Faculty of Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan
3. School of Medicine, College of Medicine, National Sun Yat-Sen University, Kaohsiung, Taiwan
Interests: lung cancer; diagnosis; prognosis; radiomics; texture analysis
Special Issues, Collections and Topics in MDPI journals
2. Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia
Interests: lung cancer; endobronchial ultrasound; thoracic ultrasound; navigational bronchoscopy; cryobiopsy
Special Issue Information
Dear Colleagues,
Contemporary pulmonary diagnostics encompasses a variety of modalities, including advanced bronchoscopy procedures such as endobronchial ultrasound, navigational and robotic bronchoscopy, cryobiopsy of lymph nodes, peripheral pulmonary nodules, and lung parenchyma. The primary goal is to obtain tissue suitable for molecular and advanced genetic analysis. It is a cornerstone for the treatment of lung cancer and interstitial pulmonary diseases.
The rapid development of new technologies, such as artificial intelligence and the widespread use of so-called “-OMICS” approaches, enables the generation of big data and opens new horizons in the exploration of potential diagnostic approaches for lung disease. Large efforts are being made to establish new biomarkers for various respiratory conditions, sampled non-invasively (or minimally invasively) from biological fluids such as blood plasma or induced sputum, aiming to minimize potentially more harmful procedures such as bronchoscopy and radiation exposure from transthoracic biopsy guided by a CT scan.
Tobacco smoking significantly contributes to the burden of pulmonary diseases. It is well recognized that cigarette smoking is a major risk factor for the development of lung cancer and chronic obstructive lung disease, namely emphysematous tissue destruction. Additionally, cigarette smoking has been associated with idiopathic pulmonary fibrosis. A distinct mechanism and molecular pathways of cigarette smoking-related lung conditions, particularly lung cancer, emphysema, and fibrosis, are permanently in focus for respiratory specialists and researchers.
COPD, as one of the world’s leading causes of death, poses a major health risk on a global scale. COPD is a disease with many faces, and it is currently not clear which COPD patients will develop underlying emphysema. Namely, COPD patients with emphysema have lower exercise capacity, worse lung function, and higher disease mortality. Additionally, COPD patients with emphysema (emphysema-predominant phenotype or concurrent emphysema and chronic bronchitis) have higher cardiovascular risk than COPD patients without emphysema. It is, therefore, crucial to accurately phenotype COPD patients, develop novel diagnostic approaches to identify emphysema, and identify distinct molecular pathways that may be altered in this specific phenotype.
Dr. Fu-Zong Wu
Dr. Nevenka Piskac Zivkovic
Guest Editors
Manuscript Submission Information
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Keywords
- endobronchial ultrasound
- navigational bronchoscopy
- robotic bronchoscopy
- cryobiopsy
- lung cancer
- interstitial lung diseases
- OMICS approaches
- proteomics
- emphysema
- chronic obstructive pulmonary disease
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