Special Issues

Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Machine Learning Approaches for the Diagnosis of Sleep and Respiratory Disorders
edited by , Shyam Subramanian and
submission deadline 30 Sep 2026 | Viewed by 637 | Submission Open
Keywords: diagnostics; artificial intelligence; sleep; respiratory disorders; healthcare
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Applications of Optical Coherence Tomography in the Ocular Diagnosis: From the Tear Film to the Sclera 2.0 submission deadline 30 Sep 2026 | 1 articles | Viewed by 540 | Submission Open
Keywords: optical coherence tomography; optical coherence tomography angiography; corneal curvature; tear film; central corneal thickness; glaucoma; anterior chamber; iris angiography; macular thickness; choroidal thickness; axial length measurement; retinal vascular plexuses; choroidal vasculature; macular surgery
(This special issue belongs to the Section Biomedical Optics)
Feature Review Papers in Histopathology
edited by Dong Ren
submission deadline 30 Sep 2026 | Viewed by 510 | Submission Open
Keywords: histopathological features; histologic subtypes; diagnostic dilemma and pitfall; ancillary testing; tumor pathogenesis
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Advanced Diagnostics in Women's Health: From Biomarkers to Imaging
edited by
submission deadline 30 Sep 2026 | 1 articles | Viewed by 490 | Submission Open
Keywords: women’ s health diagnostics; biomarkers; medical imaging; ultrasound; risk stratification; early diagnosis; precision medicine; obstetrics and gynaecology; non-invasive diagnostics; artificial intelligence
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Clinical Updates in Diagnosis and Management of Thrombocytopenia
edited by Maria Eva Mingot-Castellano and Cristina Pascual-Izquierdo
submission deadline 30 Sep 2026 | Viewed by 482 | Submission Open
Keywords: ITP; bleeding; thrombosis; anticoagulant; antiplatelet
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
AI-Powered Medical Image Diagnosis: From Algorithm Development to Clinical Validation
edited by
submission deadline 30 Sep 2026 | 1 articles | Viewed by 466 | Submission Open
Keywords: artificial intelligence  ; medical image diagnosis  ; deep learning  ; clinical validation  ; diagnostic accuracy
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Pediatric Musculoskeletal Radiology Diagnosis: From Imaging Signs to Clinical Decisions
edited by Dhouib Amira
submission deadline 30 Sep 2026 | 1 articles | Viewed by 432 | Submission Open
Keywords: pediatric bone disorders; inflammatory bone disease; musculoskeletal infection; imaging signs; advanced MRI techniques
(This special issue belongs to the Section Medical Imaging and Theranostics)
Recent Advances in Radiomics for Medical Imaging: Second Edition
edited by
submission deadline 30 Sep 2026 | Viewed by 334 | Submission Open
Keywords: radiomics; PET/CT; SPECT/CT; medical imaging; cancers
(This special issue belongs to the Section Medical Imaging and Theranostics)
Periodontal Disease: Diagnosis and Management, 2nd Edition submission deadline 30 Sep 2026 | Viewed by 304 | Submission Open
Keywords: periodontal disease  ; periodontitis  ; management  ; diagnosis  ; biomarker  ; periodontology
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Integrative Computational Neuropathology: Multimodal Approaches for Precision Diagnosis
edited by Timothy E. van Meter
submission deadline 30 Sep 2026 | Viewed by 275 | Submission Open
Keywords: computational neuropathology; neurology; brain; spinal cord; multiplex; biomarkers; automated imaging; artificial intelligence; automated diagnosis; machine learning; precision medicine
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Diagnostic Innovations in Metabolic Diseases Management
edited by and Angela Cozma
submission deadline 30 Sep 2026 | Viewed by 273 | Submission Open
Keywords: metabolic diseases; cardio-reno-metabolic syndrome; obesity; metabolic syndrome
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Innovations in Diagnosis and Management of Cardiovascular Diseases
edited by and José Luiz Barros Pena
submission deadline 30 Sep 2026 | 1 articles | Viewed by 261 | Submission Open
Keywords: diagnosis; artificial intelligence; cardiovascular diseases
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Laboratory Diagnosis of Cardiovascular Diseases
edited by Ibrahim A. Hashim
submission deadline 30 Sep 2026 | Viewed by 206 | Submission Open
Keywords: laboratory diagnostics; cardiovascular diseases; biomarkers; metabolomics; point-of-care testing; artificial intelligence  
(This special issue belongs to the Section Clinical Laboratory Medicine)
Advances in Diagnostic Testing for Esophageal Diseases
edited by
submission deadline 30 Sep 2026 | Viewed by 202 | Submission Open
Keywords: esophageal diseases; endoscopy; diagnostic tools; diagnostic testing; artificial intelligence
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
AI-Driven Innovations in Medical Imaging and Diagnostics
edited by
submission deadline 30 Sep 2026 | Viewed by 198 | Submission Open
Keywords: artificial intelligence; medical imaging; diagnosis; foundation models; generative AI; clinical decision support
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Clinical Advances in Diagnosis and Prognosis of Urological Diseases
edited by
submission deadline 30 Sep 2026 | Viewed by 187 | Submission Open
Keywords: urological diagnostics; prognostic biomarkers; artificial intelligence in urology; precision medicine; liquid biopsy; advanced imaging; prostate cancer; bladder cancer; kidney cancer; clinical risk stratification
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Recent Advancements in the Diagnosis and Prognosis of Thoracic Diseases
edited by Marco Andolfi
submission deadline 30 Sep 2026 | Viewed by 182 | Submission Open
Keywords: quality of life; risk stratification; thoracic diseases; circulating biomarkers; tissue biomarkers
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Advances in Diagnostic Modalities for Benign Upper Gastrointestinal Disorders
edited by Gad Marom and Daniel Solomon
submission deadline 30 Sep 2026 | Viewed by 161 | Submission Open
Keywords: upper gastrointestinal tract; benign disorders; endoscopy; high resolution manometry; computerized tomography; barium swallow study; EndoFLIP
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Advanced Electrocardiogram for Clinical Applications
edited by Francesco Luzza
submission deadline 30 Sep 2026 | Viewed by 148 | Submission Open
Keywords: cardiac electrophysiology; atrial fibrillation; arrhythmias; ventricular tachycardia; brugada pattern; QT interval; early repolarization; sudden cardiac death; myocardial ischemia; cardiomyopathies
(This special issue belongs to the Section Medical Imaging and Theranostics)
Sarcoidosis: Current Landscape and Future Developments
edited by and Fotios Drakopanagiotakis
submission deadline 30 Sep 2026 | Viewed by 132 | Submission Open
Keywords: sarcoidosis; diagnosis; prognosis; biomarkers; imaging; histopathology; clinical presentation; diagnostic criteria; multidisciplinary approach; treatment; treatment algorithm
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Ocular Inflammation: Progress and Pitfalls in Diagnosis, Imaging and Management submission deadline 1 Oct 2026 | 1 articles | Viewed by 280 | Submission Open
Keywords: uveitis; intraocular inflammation; fluorescein angiography (FA); indocyanine green angiography (ICGA); optical coherence tomography (OCT); enhanced depth imaging OCT (EDI-OCT); optical coherence tomography angiography (OCT-A); fundus autofluorescence (FAF); uveitis masquerades; intraocular interleukin assays; Vogt– Koyanagi– Harada disease (VKH); multiple evanescent white dot syndrome (MEWDS); consensus definitions
(This special issue belongs to the Section Medical Imaging and Theranostics)
AI for Precision Diagnostics: Enhancing Accuracy, Accessibility, and Outcomes
edited by and Mirza Mansoor Baig
submission deadline 30 Oct 2026 | 8 articles | Viewed by 5782 | Submission Open
Keywords: precision diagnostics; medical imaging and radiology; machine learning; deep learning; and transformers; biosensors and wearable health devices; explainable AI; point-of-care and remote diagnostic systems; digital health; edge AI and computing; bioinformatics; personalized medicine and health; healthcare accessibility
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
Beyond the Joint: Advances in Musculoskeletal Imaging and Sports Radiology
edited by
submission deadline 30 Oct 2026 | Viewed by 381 | Submission Open
Keywords: sports radiology; musculoskeletal imaging; diagnostic imaging; artificial intelligence; orthopaedics; extreme sports; outdoor sports; outdoor physical activity; one health; health policy
(This special issue belongs to the Section Medical Imaging and Theranostics)
Advances in the Diagnosis and Treatment of Infections of the Central Nervous System
edited by and Raffaella Capasso
submission deadline 31 Oct 2026 | 2 articles | Viewed by 29205 | Submission Open
Keywords: central nervous system infections; meningitis; HIV; tuberculosis; magnetic resonance imaging
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Advances in Computed Tomography Imaging for Clinical Diagnosis—2nd Edition
edited by Ibrahim Yel
submission deadline 31 Oct 2026 | 8 articles | Viewed by 16005 | Submission Open
Keywords: computed tomography imaging; clinical diagnosis; dual-energy CT; photon-counting CT; image analysis
(This special issue belongs to the Section Medical Imaging and Theranostics)
Challenges in Monitoring and Diagnosis in Medical Sciences
edited by and
submission deadline 31 Oct 2026 | 4 articles | Viewed by 12438 | Submission Open
Keywords: diagnostic; monitoring; medical sciences
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Updates in Vascular and Endovascular Surgery: Pathology, Diagnosis and Management
edited by Ombretta Martinelli and
submission deadline 31 Oct 2026 | 7 articles | Viewed by 7559 | Submission Open
Keywords: aneurysms of the aorta; aneurysms of the arch; arterial stenosis; EVAR (endovascular aneurysm repair); FEVAR (fenestrated endovascular aneurysm repair); BEVAR (branched endovascular aneurysm repair); iliac branches; varicose veins; venous insufficiency; chronic obstructive arteriopathy
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Diagnosis and Prognosis of Abdominal Diseases
edited by
submission deadline 31 Oct 2026 | 6 articles | Viewed by 7214 | Submission Open
Keywords: diagnosis; prognosis; abdominal diseases; markers; screening
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Integrative Approaches in Head and Neck Cancer Imaging
edited by
submission deadline 31 Oct 2026 | 3 articles | Viewed by 7126 | Submission Open
Keywords: head and neck cancer; imaging technologies; multimodal imaging; image-guided therapy; artificial intelligence in imaging
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
New Insights into Gastrointestinal Endoscopy submission deadline 31 Oct 2026 | 4 articles | Viewed by 5500 | Submission Open
Keywords: diagnosis; prognosis; gastrointestinal endoscopy; markers; clinical practice and patient care
(This special issue belongs to the Section Biomedical Optics)
Diagnosis and Management of Liver Diseases, Third Edition
edited by
submission deadline 31 Oct 2026 | 4 articles | Viewed by 5454 | Submission Open
Keywords: liver diseases; fatty liver; liver cirrhosis; viral hepatitis; hepatocellular carcinoma; diagnosis and management
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Recent Advances in the Diagnosis and Prognosis of Lung Cancer
edited by Naomi Takemura
submission deadline 31 Oct 2026 | 4 articles | Viewed by 4895 | Submission Open
Keywords: lung cancer; molecular biomarkers; artificial intelligence; early detection; precision detection; medical imaging
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Clinical Diagnosis and Prognosis of Steatotic Liver Disease submission deadline 31 Oct 2026 | 4 articles | Viewed by 4575 | Submission Open
Keywords: steatotic liver disease— SLD; steatohepatitis; steatosis; diagnosis; prognosis
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Advances in Pathology for Forensic Diagnosis
edited by and Vincenzo Cianci
submission deadline 31 Oct 2026 | 5 articles | Viewed by 4487 | Submission Open
Keywords: forensic pathology; forensic medicine; forensic radiology; forensic genetics; forensic toxicology; postmortem interval; forensic odontology; forensic entomology; forensic anthropology
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Optical Coherence Tomography in Non-Invasive Diagnostic Imaging submission deadline 31 Oct 2026 | 3 articles | Viewed by 4221 | Submission Open
Keywords: diagnosis; screening; marker; prognosis; optical coherence tomography; non-invasive diagnostic imaging
(This special issue belongs to the Section Biomedical Optics)
Precision Medicine for Cerebellar Disorders: From Bench to Bedside
edited by Mario Manto and
submission deadline 31 Oct 2026 | Viewed by 4158 | Submission Open
Keywords: cerebellum; cerebellar disorders; ataxia/cerebellar ataxia; preclinical research; precision medicine
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Diagnostic and Prognostic Non-Invasive Markers in Bladder Cancer
edited by and Xiao Yang
submission deadline 31 Oct 2026 | 4 articles | Viewed by 3639 | Submission Open
Keywords: bladder cancer; diagnostic and prognostic markers; non-invasive; artificial intelligence
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Advances in Oral Pathology of Basic and Clinical Cancer Research
edited by
submission deadline 31 Oct 2026 | 3 articles | Viewed by 3555 | Submission Open
Keywords: oral cancer; molecular pathology; tumor microenvironment (TME); immunotherapy; epigenetics; diagnosis; targeted therapy; personalized medicine; AI and image analysis
(This special issue belongs to the Section Pathology and Molecular Diagnostics)
Novel Optical Imaging Technologies in Ophthalmology and Neuroscience: Advances and Applications
edited by
submission deadline 31 Oct 2026 | 4 articles | Viewed by 3411 | Submission Open
Keywords: optical imaging; ophthalmology; neuroscience; diagnosis; prognosis
(This special issue belongs to the Section Biomedical Optics)
Advancements and Innovations in the Diagnosis of Lung Cancer submission deadline 31 Oct 2026 | 3 articles | Viewed by 3353 | Submission Open
Keywords: lung cancer; diagnosis; biomarkers; artificial intelligence; robotic bronchoscopy; bronchoscopic imaging; endobronchial ultrasound; molecular profiling; genetic profiling; next-generation sequencing; tissue acquisition; low-dose CT screening; personalized medicine; medical imaging; lung nodules
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Clinical Diagnostics and Management of Stroke
edited by
submission deadline 31 Oct 2026 | 2 articles | Viewed by 3115 | Submission Open
Keywords: ischemic stroke; diagnostic; thrombolysis; endovascular thrombectomy; post-stroke cognitive impairment; secondary prevention; neuroinflammation; neuroprotection
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Cardiovascular Diseases: Advances in Echocardiography and Cardiac Computed Tomography
edited by Vasileios Kamperidis
submission deadline 31 Oct 2026 | 2 articles | Viewed by 3100 | Submission Open
Keywords: heart failure; echocardiography; valvular heart disease; strain imaging; cardiac computed tomography; atherosclerosis; cardiomyopathy; 3D imaging; coronary artery disease; CT FFR; perfusion imaging; stress echocardiography; TEE
(This special issue belongs to the Section Medical Imaging and Theranostics)
Advances in Diagnostic Imaging for Maternal–Fetal Medicine
edited by
submission deadline 31 Oct 2026 | 1 articles | Viewed by 2919 | Submission Open
Keywords: prenatal diagnosis; fetal ultrasound; fetal MRI; congenital anomalies; placental imaging; artificial intelligence in imaging
(This special issue belongs to the Section Medical Imaging and Theranostics)
New Developments in the Diagnosis of Skin Tumors: 2nd Edition
edited by
submission deadline 31 Oct 2026 | Viewed by 2858 | Submission Open
Keywords: basal cell carcinoma; melanoma; benign tumors; cutaneous squamous cell carcinoma; Bowen’ s disease; actinic keratosis; diagnosis; biomarkers; imaging techniques; molecular diagnostics; histopathology; precision medicine
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Diagnostic Progress in Gynecologic Oncology
edited by
submission deadline 31 Oct 2026 | 3 articles | Viewed by 2733 | Submission Open
Keywords: gynecologic oncology; early diagnosis; molecular diagnostics; imaging techniques; artificial intelligence; biomarkers; cervical cancer; endometrial cancer; ovarian cancer; personalized medicine
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Diagnostic Biomarkers of Urological Diseases submission deadline 31 Oct 2026 | 1 articles | Viewed by 2656 | Submission Open
Keywords: proteomics; biomarkers; diagnosis; prediction; treatment; clinical application; technical advances
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Clinical Diagnosis and Management in Emergency and Hospital Medicine–2nd Edition
edited by
submission deadline 31 Oct 2026 | Viewed by 2610 | Submission Open
Keywords: diagnosis; treatment; management; hospital medicine; emergency medicine; point-of-care ultrasound; decision making; transitional care; palliative care; quality improvement
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Recent Advances in Maternal–Fetal Medicine
edited by Roxana Elena Bohiltea
submission deadline 31 Oct 2026 | 1 articles | Viewed by 2608 | Submission Open
Keywords: maternal– fetal medicine; pregnancy; prenatal care
(This special issue belongs to the Section Clinical Diagnosis and Prognosis)
Advances in Laboratory Medicine—from Research to Clinical Implementation
edited by Kelvin Y. K. Chan and Sergio Bernardini
submission deadline 31 Oct 2026 | Viewed by 2292 | Submission Open
Keywords: laboratory medicine; clinical practice; laboratory diagnosis; artificial intelligence
(This special issue belongs to the Section Clinical Laboratory Medicine)
Machine Learning for Medical Image Processing and Analysis in 2026
edited by Wei Shao
submission deadline 31 Oct 2026 | 2 articles | Viewed by 2241 | Submission Open
Keywords: machine learning; medical image processing; diagnostic accuracy; healthcare; algorithms
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
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