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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Current Diagnosis and Management of Metabolic Bone Diseases

edited by Liming Xiong

submission deadline 31 Dec 2026 | 3 articles | Viewed by 4697 | Submission Open

Keywords: metabolic bone disease; bone turnover markers; maintenance of bone homeostasis; multiorgan–bone axis; fracture risk assessment; diabetic osteopathy; precision management

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Biochemical Testing Applications in Clinical Diagnosis—2nd Edition

edited by

Donatella Coradduzza

submission deadline 31 Dec 2026 | 5 articles | Viewed by 4541 | Submission Open

Keywords: biochemical testing; clinical diagnosis; biomarkers; point-of-care tests; innovative analytical techniques

(This special issue belongs to the Section Clinical Laboratory Medicine)

Pathological Speech Classification and Processing for Advanced Medical Diagnosis

edited by

Juan Rafael Orozco-Arroyave

submission deadline 31 Dec 2026 | 2 articles | Viewed by 4478 | Submission Open

Keywords: pathological speech; medical diagnosis; classification and processing; Parkinson's disease; hypokinetic dysarthria; dysarthria; aphasia; voice disorders; dysphonia; AI

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Ultrasound Imaging in Medicine in 2026

edited by

Michael Bachmann Nielsen

submission deadline 31 Dec 2026 | 3 articles | Viewed by 4428 | Submission Open

Keywords: 3D ultrasound; blood flow velocity; ultrasonography; contrast-enhanced ultrasound; elasticity imaging; endoscopic ultrasound; intervention

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnostics in Maxillofacial Oncology and Trauma

edited by

Ioanna Kalaitsidou

and

Benoît Schaller

submission deadline 31 Dec 2026 | 2 articles | Viewed by 4348 | Submission Open

Keywords: maxillofacial diagnostics; craniofacial trauma; oral and maxillofacial oncology; artificial intelligence in imaging; photon-counting CT (PCCT); molecular biomarkers; histopathology; radiomics; multimodal imaging; preoperative planning

(This special issue belongs to the Section Medical Imaging and Theranostics)

Artificial Intelligence in Medical Image Analysis and Clinical Decision Support

edited by Zahid Ullah and Tahir Mahmood

submission deadline 31 Dec 2026 | 7 articles | Viewed by 4118 | Submission Open

Keywords: medical image analysis; deep learning; vision transformers; medical image segmentation; clinical decision support; multimodal learning; explainable AI; continual learning; federated learning; healthcare AI

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Diagnostic Imaging and Interpretation in Pediatric Radiology

edited by

André Lollert

submission deadline 31 Dec 2026 | 6 articles | Viewed by 4074 | Submission Open

Keywords: pediatric radiology; pediatric MRI; pediatric CT; photon-counting CT; pediatric ultrasound; clinico-radiologic diagnostics; rare diseases; quantitative imaging; artificial intelligence; nuclear medicine

(This special issue belongs to the Section Medical Imaging and Theranostics)

Clinical and Laboratory Diagnosis of Inherited Metabolic Diseases in Children

edited by

Patryk Lipiński

submission deadline 31 Dec 2026 | 2 articles | Viewed by 3894 | Submission Open

Keywords: newborn screening; selective screening; inherited metabolic disease; biochemical diagnostics; biomarkers; molecular analysis; next-generation sequencing

(This special issue belongs to the Section Clinical Laboratory Medicine)

Artificial Intelligence in Diagnostic Imaging

edited by Arthur Rodriguez Gonzalez Cortes

submission deadline 31 Dec 2026 | 2 articles | Viewed by 3642 | Submission Open

Keywords: artificial intelligence; deep learning; large language models; convolutional neural networks; radiology

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis and Prognosis of Pulmonary Diseases

edited by

Fabio Perrotta

and

Filippo Scialò

submission deadline 31 Dec 2026 | 2 articles | Viewed by 3614 | Submission Open

Keywords: interstitial lung disease; pulmonology; airway obstruction; pulmonary medicine; respiration disorders

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Interdisciplinary Approaches to Improve Cardiovascular Outcomes

edited by

Mihaela Hostiuc

submission deadline 31 Dec 2026 | 4 articles | Viewed by 3491 | Submission Open

Keywords: cardiovascular disease; prevention; risk factors; cardiovascular outcomes; interdisciplinarity; burden of disease

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in the Diagnostics and Management of Diseases of the Anterior Segment of the Eye

edited by

Sang Beom Han

submission deadline 31 Dec 2026 | 5 articles | Viewed by 3312 | Submission Open

Keywords: anterior segment disorder; cornea; cataract; anterior segment imaging; refractive surgery

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Decoding Complexity in Traumatic Injury Diagnosis: Forensic Approaches

edited by

Alice Chiara Manetti

and

Fabio Del Duca

submission deadline 31 Dec 2026 | 1 articles | Viewed by 3294 | Submission Open

Keywords: traumatology; forensic pathology; vitality; post-mortem examination; trauma diagnosis; forensic imaging; individual protections; job security; histology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Recent Advances in Microbiome-Based Diagnostics for Oncological Diseases: Innovations and Clinical Applications

edited by

Dana Lucia Stănculeanu

and

Adelina Silvana Gheorghe

submission deadline 31 Dec 2026 | 1 articles | Viewed by 3217 | Submission Open

Keywords: microbiome-based diagnostics; disease biomarkers; gut microbiota; cancer microbiome; metagenomics; multi-omics in diagnostics; machine learning in microbiome analysis; dysbiosis and disease; precision medicine; microbiome–host interactions

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

(Bio)sensors for Medical Diagnostics

edited by

Mihaela Badea

Akhtar Hayat

and Sehrish Bilal

submission deadline 31 Dec 2026 | 2 articles | Viewed by 2847 | Submission Open

Keywords: sensors and biosensors; medical diagnostics; biomarker detection; point-of-care testing; lab-on-a-chip; wearable health technology; nanotechnology; signal transduction; early disease detection; clinical monitoring

(This special issue belongs to the Section Point-of-Care Diagnostics and Devices)

Diagnosis of Viral Respiratory Infections, 2nd Edition

edited by

Federica Novazzi

submission deadline 31 Dec 2026 | 2 articles | Viewed by 2830 | Submission Open

Keywords: respiratory tract infections; lower respiratory tract infections (LRTIs); upper respiratory tract infections (URTIs); whole-genome sequencing (WGS); immunological techniques

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Artificial Intelligence in Sports Medicine: Diagnosis and Management

edited by Anca Ionescu

submission deadline 31 Dec 2026 | 1 articles | Viewed by 2692 | Submission Open

Keywords: sports medicine; sports cardiology; exercise physiology; artificial intelligence; athlete health; performance monitoring; biomarkers; sports nutrition; injury prevention; rehabilitation; wearable technology; clinical validation

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Clinical Prognostic and Predictive Biomarkers, 4th Edition

edited by

Yuli Huang

and

Peisong Chen

submission deadline 31 Dec 2026 | 4 articles | Viewed by 2630 | Submission Open

Keywords: biomarkers; prognostic; predictive; risk stratification; cardiovascular disease; diabetes; cancer; hypertension; heart failure

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Clinical Diagnosis and Treatment of Otolaryngology Diseases

edited by Lichun Hsieh

submission deadline 31 Dec 2026 | 2 articles | Viewed by 2510 | Submission Open

Keywords: otolaryngology; diagnostic imaging; minimally invasive surgery; precision medicine; head and neck diseases; clinical management

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advancements in Maternal–Fetal Medicine: 3rd Edition

edited by

Elena Bernad

submission deadline 31 Dec 2026 | 4 articles | Viewed by 2502 | Submission Open

Keywords: maternal–fetal medicine; high-risk pregnancy; prenatal diagnostics; psychological distress in pregnancy; anxiety and depression; stress-related disorders; biomarkers; perinatal morbidity and mortality; translational diagnostics

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Clinical Anatomy and Diagnosis in 2026

edited by Ji-Hyun Lee

submission deadline 31 Dec 2026 | 3 articles | Viewed by 2500 | Submission Open

Keywords: clinical anatomy; radiological anatomy; applied anatomy; anatomical variations; pathoanatomy; artificial intelligence in anatomy; anatomical research innovation; anatomical education

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Hematologic Tumors of the Bone: From Diagnosis to Prognosis

edited by Fabio Stagno

submission deadline 31 Dec 2026 | 1 articles | Viewed by 2483 | Submission Open

Keywords: bone marrow tumors; hematologic malignancies; diagnostic biomarkers; prognostic tools; targeted therapies

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Imaging for Kidney Disease: Innovations in Diagnosis and Monitoring

edited by Abhilash Koratala

submission deadline 31 Dec 2026 | 1 articles | Viewed by 2369 | Submission Open

Keywords: renal imaging; ultrasound innovations; precision diagnostics

(This special issue belongs to the Section Medical Imaging and Theranostics)

Inflammatory Pathways and Diagnostic Strategies in Chronic Diseases

edited by

Liliana-Georgeta Foia

Maria Alexandra Mârțu

and

Minerva Codruta Badescu

submission deadline 31 Dec 2026 | 2 articles | Viewed by 2132 | Submission Open

Keywords: chronic diseases; early diagnosis; non-invasive diagnosis; artificial intelligence application

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Molecular Diagnostics in Cardiovascular Diseases: From Biomarkers to Individualized Medicine

edited by

Priyanka Gokulnath

and

Michail Spanos

submission deadline 31 Dec 2026 | 2 articles | Viewed by 2068 | Submission Open

Keywords: molecular diagnostics; cardiovascular diseases; biomarkers; individualized medicine; precision cardiology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

AI-Powered Ophthalmic Diagnostics: From Image Segmentation to Disease Classification

edited by

Yanwu Xu

Weihua Yang

and

Huihui Fang

submission deadline 31 Dec 2026 | 2 articles | Viewed by 2048 | Submission Open

Keywords: ophthalmic artificial intelligence; medical image segmentation; disease classification; ocular imaging; deep learning and foundation models; explainable AI (XAI); clinical translation in ophthalmology

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Emerging Technologies for Lung Disease Detection and Clinical Assessment

edited by Scott Matson and

Joshua Jay Reicher

submission deadline 31 Dec 2026 | 3 articles | Viewed by 2017 | Submission Open

Keywords: medical imaging; artificial intelligence (AI); radiology; machine learning (ML)

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Clinical Diagnosis and Management of Liver Diseases

edited by

Jiang Liu

submission deadline 31 Dec 2026 | 2 articles | Viewed by 2003 | Submission Open

Keywords: primary liver cancer; metastatic liver cancer; liver transplantation; diagnosis; prognosis; biomarkers

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

A New Era in Diagnosis: From Biomarkers to Artificial Intelligence, 2nd Edition

edited by

Tudor Drugan

and

Daniel Leucuta

submission deadline 31 Dec 2026 | 3 articles | Viewed by 1962 | Submission Open

Keywords: biomarkers; diagnosis; personalized medicine; therapeutic strategies; artificial intelligence; machine learning

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Artificial Intelligence in Eye Disease, Fifth Edition

edited by

Jae-Ho Han

submission deadline 31 Dec 2026 | 2 articles | Viewed by 1960 | Submission Open

Keywords: medical diagnosis; artificial intelligence; deep learning; fundus image; optical coherence tomography; ophthalmology; retinal vessel; glaucoma; retinopathy; macular degeneration; image segmentation

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Recent Advances in Oral and Maxillofacial Surgery: Diagnosis and Management

edited by Kenji Yamagata

submission deadline 31 Dec 2026 | 4 articles | Viewed by 1912 | Submission Open

Keywords: oral and maxillofacial surgery; oral diseases; oral cancer; jaw deformity; orthognathic surgery

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Whole-Body PET/CT: From Diagnosis to Prognosis

edited by Ioannis M. Tsougos

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1873 | Submission Open

Keywords: whole-body PET/CT; diagnosis; prognosis; human diseases; medical imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Diagnostic and Operative Hysteroscopy, 2nd Edition

edited by

Panagiotis Christopoulos

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1795 | Submission Open

Keywords: hysteroscopy; diagnosis; technique; malformation; uterus; endometrial; anomaly; minimally invasive; pathology

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in the Diagnosis and Management of Autoimmune Diseases

edited by

Micol Romano

and

Dimitri Poddighe

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1760 | Submission Open

Keywords: autoimmunity; autoinflammatory diseases; rheumatology; innovative and biological therapies; comorbidity; immune-mediated manifestations

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Artificial Intelligence in Women’s Cardiovascular Health: Advances in Diagnosis, Screening, and Risk Prediction

edited by

Jasjit S. Suri

and

Luca Saba

submission deadline 31 Dec 2026 | 2 articles | Viewed by 1734 | Submission Open

Keywords: artificial intelligence; women’s cardiovascular health; diagnosis; screening; risk prediction

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Diagnosis and Management of Hepatitis

edited by

Qi Wang

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1674 | Submission Open

Keywords: viral hepatitis; hepatitis B virus hepatitis; drug-induced liver injury; autoimmune hepatitis; metabolic-associated fatty liver disease; alcoholic liver disease; diagnosis; follow-up management

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Advanced Ultrasound Techniques in Diagnosis, Second Edition

edited by

Laith Riyadh Sultan

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1585 | Submission Open

Keywords: super-resolution imaging; microvascular imaging (MVI); contrast-enhanced ultrasound; AI-guided ultrasound; quantitative analysis; diagnostic imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Chronic Kidney Diseases: Diagnosis, Management, and Prognosis

edited by

Xujie Zhou

submission deadline 31 Dec 2026 | Viewed by 1536 | Submission Open

Keywords: chronic kidney diseases; IgA nephropathy; biomarkers; molecular mechanisms; therapeutic innovation; personalized medicine; translational research

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Clinical Diagnostics and Management in the ICU

edited by

Silvia De Rosa

and Sergio Lassola

submission deadline 31 Dec 2026 | 4 articles | Viewed by 1489 | Submission Open

Keywords: intensive care unit; hemodynamic monitoring; acute kidney injury; sepsis and septic shock; clinical diagnostics; predictive biomarkers

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Fetal Diagnosis and Therapy: 2nd Edition

edited by Elisa Montaguti and Camilla Dionisi

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1407 | Submission Open

Keywords: ultrasound; prenatal diagnosis; NIPT; fetal echocardiography; fetal therapy; fetal MRI

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Sarcoma Diagnostics: Histopathology, Imaging, and Artificial Intelligence for Precision Management

edited by

Siu Wai Choi

submission deadline 31 Dec 2026 | Viewed by 1354 | Submission Open

Keywords: sarcoma diagnosis and prognosis; machine learning models; genomics in diagnosis; classification and prognosis; novel methods of treatment

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Update on Diagnosis in Cardiovascular Interventions

edited by

Alfredo E. Rodriguez

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1316 | Submission Open

Keywords: myocardial infarction; stents; coronary artery disease; drugs; coronary imaging; structural heart disease; meta-analysis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in the Diagnosis, Prognosis, and Management of the Musculoskeletal System

edited by

Massimiliano Leigheb

Alessandro de Sire

and Cesar de Cesar Netto

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1304 | Submission Open

Keywords: musculoskeletal system; diagnostic tools; prognosis; artificial intelligence; augmented reality

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnostic Advances in Orthodontics and Dentistry

edited by

Antonino Lo Giudice

submission deadline 31 Dec 2026 | 2 articles | Viewed by 1295 | Submission Open

Keywords: CBCT facial scanning; oral imaging; orthodontics; digital dentistry; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in the Diagnosis and Management of Autoimmune Rheumatic Diseases

edited by

Liangjing Lu

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1244 | Submission Open

Keywords: autoimmune rheumatic diseases; biomarkers; precision medicine; targeted therapy; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Cancer Diagnosis and Intervention

edited by Vlad Alexandru Gâta

submission deadline 31 Dec 2026 | 3 articles | Viewed by 1163 | Submission Open

Keywords: diagnostic; precision oncology; artificial intelligence; radiomics; molecular biomarkers; interventional oncology; personalized medicine; translational research

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Accurate Diagnosis and Management of Infectious and Respiratory Diseases

edited by

Marco Goeijenbier

submission deadline 31 Dec 2026 | 3 articles | Viewed by 1143 | Submission Open

Keywords: infectious and respiratory diseases; viral and bacterial pathogens; multiplex molecular panels; rapid diagnostic tests; intensive care units

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Prostate Cancer: Innovations in Diagnosis and Risk Stratification

edited by Biren Saraiya

submission deadline 31 Dec 2026 | 1 articles | Viewed by 1035 | Submission Open

Keywords: prostate cancer; diagnostics; therapeutics; molecular targets; Prostate Specific Membrane Antigen (PSMA); risk stratification; radioligand therapy; multimodal therapy; clinical guidelines

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Medical Microbiology and Infection: Diagnosis and Management

edited by

Hsinyao Wang

submission deadline 31 Dec 2026 | 2 articles | Viewed by 957 | Submission Open

Keywords: medical microbiology; infectious diseases; diagnostic microbiology; infection management; antimicrobial susceptibility testing; non‑antibiotic therapies; clinical microbiology; diagnostic innovation

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Artificial Intelligence in Epidemiological Diagnostics: Advances and Applications

edited by

Jinhui Tian

submission deadline 31 Dec 2026 | 1 articles | Viewed by 938 | Submission Open

Keywords: artificial intelligence in diagnostic epidemiology; machine learning for diagnostic screening; predictive diagnostic modeling; automated diagnostic evidence synthesis; AI-designed peptides for diagnostics; antimicrobial peptide diagnostics; AI peptide engineering for pathogen detection; AI-driven population health diagnostics; diagnostic health informatics; digital diagnostic epidemiology

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Displaying special issue 301-350 on page 7 of 14.

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