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Diagnostics
Special Issues
Clinical Diagnosis and Treatment of Otolaryngology Diseases
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Clinical Diagnosis and Treatment of Otolaryngology Diseases

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Clinical Diagnosis and Prognosis".

Deadline for manuscript submissions: 30 June 2026 | Viewed by 1201

Special Issue Editor

Dr. Lichun Hsieh

E-Mail Website
Guest Editor
1. Department of Otolaryngology-Head and Neck Surgery, MacKay Memorial Hospital, Taipei 104, Taiwan
2. Department of Audiology and Speech-Language, MacKay Medical College, New Taipei City, Taiwan
Interests: otolaryngology; cochlear implant; endoscopic ear surgery
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Otolaryngology encompasses a wide spectrum of diseases affecting the ear, nose, throat,  head and neck, which often pose significant diagnostic and therapeutic challenges. Advances in diagnostic imaging, endoscopic techniques, molecular markers, and minimally invasive surgery have greatly improved patient outcomes. This Special Issue aims to gather high-quality original research, clinical studies, and comprehensive reviews that highlight recent progress in the diagnosis and treatment of otolaryngology diseases. Topics of interest include novel diagnostic tools, innovative therapeutic strategies, surgical techniques, precision medicine, and multidisciplinary approaches to complex disorders. By bringing together diverse perspectives, this Special Issue seeks to foster collaboration among clinicians, researchers, and healthcare professionals, thereby enhancing evidence-based practice and improving the quality of care in otolaryngology.

Dr. Lichun Hsieh
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • otolaryngology
  • diagnostic imaging
  • minimally invasive surgery
  • precision medicine
  • head and neck diseases
  • clinical management

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

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10 pages, 832 KB  
Article
Postoperative Pain Following a Retroauricular Approach Versus a Transcanal Approach in Tympanoplasty Type 1: A 14-Day Retrospective Study
by Wen-Ching Chuang, Li-Chun Hsieh and Chin-Kuo Chen
Diagnostics 2026, 16(5), 675; https://doi.org/10.3390/diagnostics16050675 - 26 Feb 2026
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Abstract
Objectives: This study aimed to determine whether the surgical approach used significantly affected postoperative pain and quality of life. Methods: This retrospective study included 45 adult patients undergoing type I tympanoplasty for chronic tympanic membrane perforation. The patients were divided into [...] Read more.
Objectives: This study aimed to determine whether the surgical approach used significantly affected postoperative pain and quality of life. Methods: This retrospective study included 45 adult patients undergoing type I tympanoplasty for chronic tympanic membrane perforation. The patients were divided into two groups: transcanal (n = 24) and retroauricular (n = 21). Postoperative pain was assessed using the Wong–Baker FACES® Pain Rating Scale. Additional outcomes included analgesic use and activity limitation. Results: The graft success rates in the transcanal and retroauricular groups were 95.8% and 95.2%, respectively. The transcanal group reported significantly lower pain scores between postoperative days 5 and 8 (p < 0.05) and discontinued analgesic use earlier (mean 3.1 versus 4.3 days; p < 0.05). Furthermore, the transcanal group had fewer activity limitation events during recovery. Operative time was significantly shorter in the transcanal group (55.4 ± 10.1 versus 90.2 ± 10.6 min; p < 0.001). No major complications were observed in either group. Conclusions: A transcanal approach is associated with reduced postoperative pain, earlier recovery, and shorter analgesic use than a retroauricular approach in tympanoplasty type I. Full article
(This article belongs to the Special Issue Clinical Diagnosis and Treatment of Otolaryngology Diseases)
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26 pages, 942 KB  
Systematic Review
Diagnostic Approaches and Surgical Outcomes in Nasal Valve Dysfunction: A Systematic Review
by Mahmoud Daoud, Luana-Maria Gherasie, Maria Louise Fufezan, Răzvan Hainăroșie, Cătălina Voiosu, Andreea Rusescu, Irina-Gabriela Ioniță, Oana-Ruxandra Aliuș and Viorel Zainea
Diagnostics 2026, 16(9), 1324; https://doi.org/10.3390/diagnostics16091324 - 28 Apr 2026
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Abstract
Background: Nasal valve dysfunction (NVD) is a common yet underrecognized cause of nasal airway obstruction, with a significant impact on quality of life. Despite its clinical relevance, no universally accepted diagnostic standard exists, and optimal management remains debated. Multiple diagnostic tools and surgical [...] Read more.
Background: Nasal valve dysfunction (NVD) is a common yet underrecognized cause of nasal airway obstruction, with a significant impact on quality of life. Despite its clinical relevance, no universally accepted diagnostic standard exists, and optimal management remains debated. Multiple diagnostic tools and surgical or minimally invasive treatments have been proposed. This systematic review and meta-analysis aimed to evaluate current evidence regarding diagnostic approaches and treatment outcomes in NVD. Methods: A systematic search of PubMed/MEDLINE, Embase, and Cochrane Library was performed for studies published between January 1990 and January 2026, in accordance with PRISMA 2020 guidelines. Randomized controlled trials, non-randomized comparative studies, cohort studies, and case series (≥10 patients) assessing diagnostic methods or therapeutic interventions for NVD were included. Diagnostic data were synthesized narratively. The primary surgical outcome was change in the Nasal Obstruction Symptom Evaluation (NOSE) score. Risk of bias was assessed using RoB 2, ROBINS-I, and QUADAS-2 tools. Results: Seventy-two primary clinical studies were included (15 diagnostic, 57 treatment-focused). Objective airflow measurements, particularly rhinomanometry and peak nasal inspiratory flow, showed greater reliability than isolated clinical maneuvers. Imaging modalities provided anatomical detail but correlated inconsistently with symptoms. Meta-analysis of 12 studies (n = 1210 patients) suggests that both traditional surgical and minimally invasive interventions can substantially improve nasal breathing, with mean NOSE score reductions of 40–55 points, though heterogeneity precludes direct comparison of their relative effectiveness. Conclusions: Diagnosis of NVD requires a multimodal approach combining clinical assessment, validated symptom scores, and selective objective testing. Surgical and minimally invasive treatments provide substantial symptom improvement when appropriately indicated. Evidence is constrained by the predominance of observational data, emphasizing the need for standardized diagnostics and robust comparative trials. Full article
(This article belongs to the Special Issue Clinical Diagnosis and Treatment of Otolaryngology Diseases)
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