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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in the Diagnosis of Nervous System Diseases—3rd Edition

edited by

Vasileios T. Papaliagkas

submission deadline 31 Dec 2025 | 2 articles | Viewed by 1514 | Submission Open

Keywords: neuroimaging; neurodegenerative diseases; Alzheimer's disease; cognitive impairment; brain tumors

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Innovations in Medical Imaging for Precision Diagnostics

edited by

Tim Duong

submission deadline 31 Dec 2025 | 3 articles | Viewed by 1506 | Submission Open

Keywords: deep learning; multimodal imaging; precision medicine; single-photon emission computed tomography (SPECT); mammography; tomosynthesis; ultrasound; neurology; oncology; medicine; psychiatry

(This special issue belongs to the Section Medical Imaging and Theranostics)

Future Trends in Diagnostic and Interventional Radiology

edited by

Francesco Giurazza

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1505 | Submission Open

Keywords: diagnostic radiology; interventional radiology; medical imaging; artificial intelligence; minimally invasive therapy; radiomics; precision medicine; multidisciplinary research

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Oral Pathology of Basic and Clinical Cancer Research

edited by

Jun-Ichi Tanuma

submission deadline 31 Dec 2025 | 2 articles | Viewed by 1459 | Submission Open

Keywords: oral cancer; molecular pathology; tumor microenvironment (TME); immunotherapy; epigenetics; diagnosis; targeted therapy; personalized medicine; AI and image analysis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Recent Advances in Hematology and Oncology, 2nd Edition

edited by Chohao Lee

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1386 | Submission Open

Keywords: hematological malignancies; lymphoma; leukemia; multiple myeloma; precision medicine; immunotherapy; genomics; targeted therapies

(This special issue belongs to the Section Clinical Laboratory Medicine)

Artificial Intelligence in Gastrointestinal Disease: Diagnosis and Management in 2025

edited by

Eun-Sun Kim

and

Kwang-Sig Lee

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1316 | Submission Open

Keywords: gastrointestinal disease; artificial intelligence; gastrointestinal cancer; inflammatory bowel disease; endoscopic AI; large language models

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Hybrid PET/MR Imaging: Technological Advances and Multidisciplinary Clinical Applications

edited by

Marco Fogante

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1301 | Submission Open

Keywords: PET/MR; hybrid imaging; molecular imaging; diagnostic imaging; oncology; cardiology; neurology; senology; pediatrics; musculoskeletal imaging; precision medicine; clinical applications

(This special issue belongs to the Section Medical Imaging and Theranostics)

New Advances in Digestive Endoscopy

edited by Dominique Béchade

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1208 | Submission Open

Keywords: digestive endoscopy; colonoscopy; endoscopic ultrasound; interventional endoscopy; EUS-Guided Fine-Needle Aspiration (EUS-FNA); EUS-Fine Needle Biopsy (EUS-FNB); Endoscopic Retrograde Cholangiopancreatography (ENCR)

(This special issue belongs to the Section Biomedical Optics)

Advances in Head and Neck and Oral Maxillofacial Radiology

edited by

Hemis Qiyong Ai

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1206 | Submission Open

Keywords: medical imaging; head and neck; machine learning; radiomics analysis; medical image analysis

(This special issue belongs to the Section Medical Imaging and Theranostics)

Global Perspectives on Myopia—Epidemiology, Pathophysiology, and Emerging Assessment Technologies

edited by

Ungsoo-Samuel Kim

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1166 | Submission Open

Keywords: myopia; diagnostic imaging; optical coherence tomography (OCT); artificial intelligence (AI); biomarkers; early detection; prevention; epidemiology; digital diagnostics

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Fetal Doppler Assessment: From Basic Research to Clinical Practice

edited by Luís Guedes-Martins

submission deadline 31 Dec 2025 | 1 articles | Viewed by 999 | Submission Open

Keywords: fetal Doppler; fetal growth restriction; preeclampsia; fetal-placental hemodynamics; fetal death; placental abruption; placental circulation; fetal cerebral circulation; fetal hepatic circulation; fetal heart function

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis and Management of Meningitis—2nd Edition

edited by

Georgina Tzanakaki

submission deadline 31 Dec 2025 | 1 articles | Viewed by 947 | Submission Open

Keywords: bacterial meningitis; invasive meningococcal disease; molecular diagnostics; molecular typing; laboratory surveillance; molecular epidemiology

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Diagnostics in Focus: Accelerating Access for Priority Diseases in Africa

edited by Rosanna Peeling,

Debi Boeras

and Nicaise Ndembi

submission deadline 31 Dec 2025 | 1 articles | Viewed by 927 | Submission Open

Keywords: diagnostics; epidemic-prone diseases; outbreak preparedness and response

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

21st Century Point-of-Care, Near-Patient and Critical Care Testing—2nd Edition

edited by

Gerald J. Kost

submission deadline 31 Dec 2025 | 1 articles | Viewed by 831 | Submission Open

Keywords: point-of-care testing; infectious diseases; early detection; emergency management; disaster readiness; prehospital diagnosis; health promotion; public health resilience

(This special issue belongs to the Section Point-of-Care Diagnostics and Devices)

Diagnosis and Management of Liver Diseases, Third Edition

edited by

Jeong-Ju Yoo

submission deadline 31 Dec 2025 | 1 articles | Viewed by 820 | Submission Open

Keywords: liver diseases; fatty liver; liver cirrhosis; viral hepatitis; hepatocellular carcinoma; diagnosis and management

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Diagnosis and Treatment in Pediatric Dentistry

edited by

Patrizia Gallenzi

Edoardo Staderini

and Federica Guglielmi

submission deadline 31 Dec 2025 | 1 articles | Viewed by 816 | Submission Open

Keywords: OSA; special needs patients; interceptive orthodontics; proteomics; 3D imaging; parafunctional habits

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Novel Diagnostic Approaches and Treatment of Angina and Myocardial Ischemia

edited by

Marcin Kozuch

and

Emil Julian Dąbrowski

submission deadline 31 Dec 2025 | 1 articles | Viewed by 793 | Submission Open

Keywords: ischemia; angina; chronic coronary syndromes; ANOCA; INOCA; CMD; CFR; microcirculation; scintigraphy; CMR

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Insights into Imaging Diagnosis of Heart Disease

edited by

Michael Henein

submission deadline 31 Dec 2025 | 1 articles | Viewed by 792 | Submission Open

Keywords: cardiovascular imaging including echocardiography and CTCA; cardiovascular imaging; echocardiography; cardiac magnetic resonance; myocardial perfusion imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Pain Medicine: Diagnosis and Management

edited by Alessandro Dario

submission deadline 31 Dec 2025 | 1 articles | Viewed by 773 | Submission Open

Keywords: neuropathic pain; fibromialgia; low back pain; nociplastic pain; artificial intelligence in pain medicine; evidence-based consensus guidelines; pain measuring; cancer pain medicine; interventional pain medicine; topic analgesic for chronic pain; SPECT/CT scan

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Recent Advances in Prenatal Diagnosis and Clinical Management

edited by Silvana Arduino

submission deadline 31 Dec 2025 | 1 articles | Viewed by 743 | Submission Open

Keywords: ultrasound; prenatal diagnosis; intrauterine fetal growth restriction; monochorionic twins; perinatal morbidity; maternal complications

(This special issue belongs to the Section Medical Imaging and Theranostics)

Decoding Skin Disorders: Advanced Diagnostic Strategies and Prognostic Insights

edited by

Carmen Cantisani

submission deadline 31 Dec 2025 | 1 articles | Viewed by 435 | Submission Open

Keywords: dermatology; diagnosis; prognosis; markers; management

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Cardiac Imaging in Heart Failure

edited by

Vasileios Kamperidis

submission deadline 31 Dec 2025 | Viewed by 349 | Submission Open

Keywords: cardiac imaging; heart failure; diagnosis; management; prognosis; echocardiography; CT imaging; MRI imaging; PET CT; SPECT

(This special issue belongs to the Section Medical Imaging and Theranostics)

Arthroscopy Techniques in Diagnosis and Treatment 2025

edited by Maristella Francesca Saccomanno and

Andrea De Fazio

submission deadline 31 Dec 2025 | Viewed by 337 | Submission Open

Keywords: arthroscopy; arthroscopy techniques; sports medicine; diagnosis; biological therapies; PROMS

(This special issue belongs to the Section Biomedical Optics)

Clinical Diagnosis and Prognosis of Urologic Oncology

edited by

Juan Gómez Rivas

and Jesús Moreno Sierra

submission deadline 31 Dec 2025 | 1 articles | Viewed by 301 | Submission Open

Keywords: urologic cancers; prostate; bladder; kidney; testicular malignancies

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in the Diagnosis of Surgical Pathology

edited by Dong Ren

submission deadline 31 Dec 2025 | Viewed by 260 | Submission Open

Keywords: pathological diagnosis; diagnostic dilemma and pitfall; molecular pathology; digital pathology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Neurodiagnostics in Public Health: Cognitive Decline, Mental Health, and Emerging Technologies

edited by

Evgenia Gkintoni

and

Apostolos Vantarakis

submission deadline 31 Dec 2025 | Viewed by 258 | Submission Open

Keywords: neurocognitive disorders; dementia; mild cognitive impairment (MCI); neuropsychiatric diseases; biomarkers; imaging; artificial intelligence; digital diagnosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Image-Guided Diagnosis and Therapies for Pelvic Floor Disorders, 2nd Edition

edited by

Giulio Aniello Santoro

submission deadline 31 Dec 2025 | Viewed by 254 | Submission Open

Keywords: pelvic floor disorders; imaging; ultrasonography; fecal incontinence; obstructed defecation

(This special issue belongs to the Section Medical Imaging and Theranostics)

New Advances in Chest Imaging

edited by

Davide Colombi

submission deadline 31 Dec 2025 | Viewed by 250 | Submission Open

Keywords: chest imaging; lung cancer; interstitial lung diseases; machine learning

(This special issue belongs to the Section Medical Imaging and Theranostics)

Recent Advances in Genomics for Prenatal Diagnosis

edited by Wing-Cheong Leung and

Ye Cao

submission deadline 31 Dec 2025 | Viewed by 188 | Submission Open

Keywords: prenatal diagnosis; genetics; genomics; NIPT; WES; WGS; CRISPR; epigenetics; expanded carrier screening

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Laboratory Diagnosis of Infectious Disease: Advances and Challenges, 2nd Edition

edited by

Hung-Sheng Shang

submission deadline 31 Dec 2025 | Viewed by 155 | Submission Open

Keywords: infectious diseases; diagnostic techniques; laboratory innovation; diagnostic accuracy; global health; disease detection; diagnostic challenges; medical technology

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Advanced Imaging of Acute Ischemic Stroke and Chronic Cerebral Hypoperfusion

edited by Vittorio Stumpo,

Jorn Fierstra

and Jacopo Bellomo

submission deadline 31 Dec 2025 | Viewed by 150 | Submission Open

Keywords: acute ischemic stroke; chronic cerebral hypoperfusion; neuroimaging; reperfusion failure; vascular cognitive impairment

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in the Diagnosis and Management of Digestive System Diseases, Second Edition

edited by Jialing Huang

submission deadline 31 Dec 2025 | Viewed by 149 | Submission Open

Keywords: digestive system; pathology; liver transplantation; diagnosis; therapy

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Artificial Intelligence in Stroke Imaging: Recent Advancements

edited by Philip Hoelter

submission deadline 31 Dec 2025 | Viewed by 148 | Submission Open

Keywords: artificial intelligence; stroke imaging; deep learning; machine learning; convolutional neural networks; large vessel occlusion; prognostication; automated diagnosis

(This special issue belongs to the Section Medical Imaging and Theranostics)

Novel Biomarkers for Clinical Diagnosis and Prognosis

edited by

Ji Hyun Park

submission deadline 31 Dec 2025 | Viewed by 144 | Submission Open

Keywords: biomarkers; personalized medicine; molecular signatures; prognosis predictive diagnostics; prognostic diagnostics; genetic biomarkers; blood analysis; liquid biopsy; tumor marker

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Cardiovascular Imaging, 2nd Edition

edited by

Riemer H.J.A. Slart

submission deadline 31 Dec 2025 | Viewed by 135 | Submission Open

Keywords: cardiovascular imaging; noninvasive imaging; diagnosis; prognosis; marker

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis and Prognosis of Gynecological Diseases: Advances and Challenges

edited by Stefano Bettocchi and Stefania Carlucci

submission deadline 31 Dec 2025 | Viewed by 133 | Submission Open

Keywords: gynecological diseases; hysteroscopy; diagnostic technologies; prognostic evaluation; biomarkers; imaging techniques; artificial intelligence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

The Use of Portable Devices in Emergency Medicine, Second Edition

edited by

Junko Yamaguchi

submission deadline 31 Dec 2025 | Viewed by 126 | Submission Open

Keywords: portable devices; emergency medicine; smartphone applications; wearable technology; diagnostic accuracy; remote triage; real-time monitoring; emergency medicine education; point-of-care testing; telemedicine

(This special issue belongs to the Section Point-of-Care Diagnostics and Devices)

Infective Endocarditis in Cardiac Prosthesis and Devices

edited by José Alberto San Román-Calvar and Javier López-Díaz

submission deadline 31 Dec 2025 | Viewed by 122 | Submission Open

Keywords: infective endocarditis; valvular surgical prosthesis; TAVRs; cardiac electronic implantable devices; left ventricular assist devices

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Diagnostic and Operative Hysteroscopy, 2nd Edition

edited by

Panagiotis Christopoulos

submission deadline 31 Dec 2025 | Viewed by 112 | Submission Open

Keywords: hysteroscopy; diagnosis; technique; malformation; uterus; endometrial; anomaly; minimally invasive; pathology

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis of Corneal and Retinal Diseases

edited by

Cristina Nicula

and Alina Popa-Cherecheanu

submission deadline 31 Dec 2025 | Viewed by 111 | Submission Open

Keywords: imaging diagnosis; corneal diseases; retinal diseases; optical coherence tomography (OCT); ultrasound

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Management of Pancreatic Cancer, Second Edition

edited by Nikolaos A. Chatzizacharias and Sarah F. Powell-Brett

submission deadline 31 Dec 2025 | Viewed by 104 | Submission Open

Keywords: pancreatic cancer; genetic sequencing; diagnosis; circulating tumour cells; imaging; neoadjuvant treatment; personalised systemic treatment; survival; recurrence

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

The Role of Imaging in Liver Surgery, 2nd Edition

edited by

Mattia Garancini

submission deadline 31 Dec 2025 | Viewed by 84 | Submission Open

Keywords: imaging; liver surgery; ultrasound; radiomics; magnetic resonance

(This special issue belongs to the Section Medical Imaging and Theranostics)

Clinical Challenges and Innovations in the Diagnosis of Age-Related Macular Degeneration: A Multidisciplinary Perspective

edited by

Dun Jack Fu

and Francesca Lamanna

submission deadline 1 Jan 2026 | Viewed by 252 | Submission Open

Keywords: age-related macular degeneration (AMD); machine learning; high-resolution optical coherence tomography (OCT); multimodal imaging; multidisciplinary approach; diagnostic challenges; serum metabolite biomarkers; complement system; histological studies

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Functional Gastrointestinal Disorders (FGIDs): Diagnosis and Pathophysiology, Second Edition

edited by Gengqing Song

submission deadline 31 Jan 2026 | 4 articles | Viewed by 18560 | Submission Open

Keywords: functional gastrointestinal disorders; diagnosis; treatment approach; ROME criteria

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnosis of Cardio-Thoracic Diseases

edited by Tilman Emrich

submission deadline 31 Jan 2026 | 9 articles | Viewed by 16051 | Submission Open

Keywords: cardiac disease; aortic disease; lung disease; computed tomography; magnetic resonance imaging; echocardiography; quantitative imaging; multiparametric imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in the Diagnosis and Management of Cancer/Tumors

edited by

Damiano Caruso

submission deadline 31 Jan 2026 | 5 articles | Viewed by 15859 | Submission Open

Keywords: oncologic imaging; cancer imaging; MRI; CT; X-ray; machine learning; radiodiagnostics; theranostics

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in the Diagnosis, Prognosis, and Management of Urinary Disease

edited by

Nicola Longo

and

Massimiliano Creta

submission deadline 31 Jan 2026 | 8 articles | Viewed by 14817 | Submission Open

Keywords: urinary disease; diagnosis; prognosis; kidney disease; prostate disease; malignant diseases like kidney cancer; bladder cancer and prostate cancer

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Clinical Diagnosis of Otorhinolaryngology

edited by Nina Gale,

Primož Strojan

and Robert Šifrer

submission deadline 31 Jan 2026 | 5 articles | Viewed by 14569 | Submission Open

Keywords: head and neck cancer; otorhinolaryngology; symptoms and clinical signs

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Disease Prediction

edited by

Chi-Chang Chang

, Osman Hayran and Chalong Cheewakriangkrai

submission deadline 31 Jan 2026 | 5 articles | Viewed by 12634 | Submission Open

Keywords: early diagnostics; medical big data analytics; intelligent diagnostic models in public health; survival analysis and health hazard evaluations; machine learning and generative intelligence; intelligent digital twins; automated/intelligent laboratory recommendation systems

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

AI-Assisted Diagnostics in Telemedicine and Digital Health

edited by

Joseph Finkelstein

submission deadline 31 Jan 2026 | 4 articles | Viewed by 10869 | Submission Open

Keywords: AI; machine learning; deep learning; image analysis; digital health; healthcare; telemedicine; disease diagnosis

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

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