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Prematurity, Preterm-Born Adults, and Long-Term Effects on Children and Adults...
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Prematurity, Preterm-Born Adults, and Long-Term Effects on Children and Adults (Volume II)

A special issue of Children (ISSN 2227-9067).

Deadline for manuscript submissions: closed (25 July 2023) | Viewed by 8760

Special Issue Editor

Prof. Dr. Vasanth H.S. Kumar

E-Mail Website
Guest Editor
Department of Pediatrics, University at Buffalo, Buffalo, NY 14203, USA
Interests: BPD and hyperoxic lung injury; pulmonary hypertension; resuscitation; long-term effects of prematurity
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Advances in neonatal care have led to the improved survival of premature infants with a concurrent increase in the incidence of preterm births worldwide. However, the spectrum of preterm infants from the extremes of gestational age to late preterm infants is at high risk of adverse short-term and long-term outcomes. Bronchopulmonary dysplasia, necrotizing enterocolitis, and neurodevelopmental impairment may alter these infants' growth and development trajectory. In addition, multi-system issues may complicate growth and development even into adulthood in preterm adults.

The Special Issue will address the problems related to prematurity as infants grow into adults. Morbidities such as asthma, lung function, pulmonary hypertension, organ-specific health issues (poor feeding, gastrointestinal, metabolic, and renal morbidities), or neurodevelopmental outcomes will be covered in this Special Issue. Caffeine, oxygen, nutrition, and other factors that influence the growth and development of preterm infants will be considered. Newer strategies, including machine learning and unique approaches such as bridging pediatric and adult programs to address the research gaps in longitudinal assessment and management of premature infants, contributing to improved survival and long-term outcomes as they grow into adults, are of interest.

We welcome articles from across the globe on all matters related to prematurity and long-term health to improve the lives of these infants. Both reviews and original research will be considered for publication. Authors are welcome to contact the editor directly at vkumar3@buffalo.edu for questions or clarifications.

Prof. Dr. Vasanth H.S. Kumar
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Children is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • bronchopulmonary dysplasia
  • hyperoxia
  • prematurity
  • caffeine
  • asthma
  • adults born preterm
  • growth
  • neurodevelopment

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Published Papers (2 papers)

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Review

15 pages, 298 KiB  
Review
Prematurity and Low Birth Weight and Their Impact on Childhood Growth Patterns and the Risk of Long-Term Cardiovascular Sequelae
by Iwona Jańczewska, Jolanta Wierzba, Alicja Jańczewska, Małgorzata Szczurek-Gierczak and Iwona Domżalska-Popadiuk
Children 2023, 10(10), 1599; https://doi.org/10.3390/children10101599 - 25 Sep 2023
Cited by 18 | Viewed by 5626
Abstract
Preterm birth (before 37 completed weeks of gestation) is a global health problem, remaining the main reason for neonatal mortality and morbidity. Improvements in perinatal and neonatal care in recent decades have been associated with a higher survival rate of extremely preterm infants, [...] Read more.
Preterm birth (before 37 completed weeks of gestation) is a global health problem, remaining the main reason for neonatal mortality and morbidity. Improvements in perinatal and neonatal care in recent decades have been associated with a higher survival rate of extremely preterm infants, leading to a higher risk of long-term sequelae in this population throughout life. Numerous surveillance programs for formerly premature infants continue to focus on neurodevelopmental disorders, while long-term assessment of the impact of preterm birth and low birth weight on child growth and the associated risk of cardiovascular disease in young adults is equally necessary. This review will discuss the influence of prematurity and low birth weight on childhood growth and cardiovascular risk in children, adolescents and young adults. The risk of cardiovascular and metabolic disorders is increased in adult preterm survivors. In early childhood, preterm infants may show elevated blood pressure, weakened vascular growth, augmented peripheral vascular resistance and cardiomyocyte remodeling. Increased weight gain during the early postnatal period may influence later body composition, promote obesity and impair cardiovascular results. These adverse metabolic alterations contribute to an increased risk of cardiovascular incidents, adult hypertension and diabetes. Preterm-born children and those with fetal growth restriction (FGR) who demonstrate rapid changes in their weight percentile should remain under surveillance with blood pressure monitoring. A better understanding of lifelong health outcomes of preterm-born individuals is crucial for developing strategies to prevent cardiovascular sequelae and may be the basis for future research to provide effective interventions. Full article
(This article belongs to the Special Issue Prematurity, Preterm-Born Adults, and Long-Term Effects on Children and Adults (Volume II))
17 pages, 1037 KiB  
Review
Preterm Birth, Developmental Smoke/Nicotine Exposure, and Life-Long Pulmonary Sequelae
by Chie Kurihara, Katherine M. Kuniyoshi and Virender K. Rehan
Children 2023, 10(4), 608; https://doi.org/10.3390/children10040608 - 23 Mar 2023
Cited by 5 | Viewed by 2645
Abstract
This review delineates the main pulmonary issues related to preterm birth, perinatal tobacco/nicotine exposure, and its effects on offspring, focusing on respiratory health and its possible transmission to subsequent generations. We review the extent of the problem of preterm birth, prematurity-related pulmonary effects, [...] Read more.
This review delineates the main pulmonary issues related to preterm birth, perinatal tobacco/nicotine exposure, and its effects on offspring, focusing on respiratory health and its possible transmission to subsequent generations. We review the extent of the problem of preterm birth, prematurity-related pulmonary effects, and the associated increased risk of asthma later in life. We then review the impact of developmental tobacco/nicotine exposure on offspring asthma and the significance of transgenerational pulmonary effects following perinatal tobacco/nicotine exposure, possibly via its effects on germline epigenetics. Full article
(This article belongs to the Special Issue Prematurity, Preterm-Born Adults, and Long-Term Effects on Children and Adults (Volume II))
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