Special Issue "Key Signalling Molecules in Aging and Neurodegeneration"
Deadline for manuscript submissions: 15 June 2021.
Interests: Ca2+ homeostasis; mitochondria; endoplasmic reticulum; oraganelle contact sites; MAM; bioenergetics; Alzheimer's disease; presenilin; neurodegeneration
Assistant Guest Editor
Interests: Ca2+ homeostasis; Alzheimer's disease; presenilin; neurodegeneration; mitochondria; endoplasmic reticulum; organelle contact sites; MAM; bioenergetics; metabolism
The human lifespan has drastically increased in the past decades and the percentage of the aged population is constantly rising, posing major health and economic challenges. Aging invariably increases the risk of several diseases, such as those linked to neurodegeneration, cancer, stroke and diabetes. In this Special Issue, the focus will be on neurodegenerative disorders of the elderly, particularly Parkinson and Alzheimer diseases. Both conditions are characterized by the progressive degeneration of specific neuronal circuits, through largely unknown pathogenic mechanisms, and are devoid of valid therapeutic approaches. Therefore, the need to find novel targets and early biomarkers to develop appropriate pharmacological strategies appears urgent. In this scenario, precise knowledge of the specific cellular and molecular processes behind aging and neurodegeneration is a priority for the scientific community.
The aim of this Special Issue is to provide an overview of the main signalling pathways and molecules involved in the process of aging, highlighting their intimate connection with the onset of neurodegenerative disorders.
Prof. Paola Pizzo
Dr. Riccardo Filadi
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- oxidative stress
- ER stress