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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Novel Therapeutic Classes in Lung Cancer

edited by

Rajat Thawani

and

Rohit Singh

submission deadline 31 Dec 2026 | Viewed by 259 | Submission Open

Keywords: non-small-cell lung cancer; small-cell lung cancer; antibody–drug conjugates; bispecific antibodies; resistance mechanisms; precision oncology; immunotherapy combinations

(This special issue belongs to the Section Cancer Therapy)

Advancing Theranostics in Oncology: Radiopharmaceuticals from Discovery to Clinical Applications

edited by Hwan Lee, Joseph Lau and

Etienne Rousseau

submission deadline 31 Dec 2026 | Viewed by 255 | Submission Open

Keywords: theranostics; radiopharmaceutical; positron emission tomography; single photon emission computed tomography; targeted radionuclide therapy; dosimetry; cancer

Oncological Outcomes of Active Surveillance Versus Radical Treatment in Localized Prostate Cancer

edited by

Maciej Salagierski

submission deadline 31 Dec 2026 | Viewed by 228 | Submission Open

Keywords: active surveillance; molecular markers; multiparametric magnetic resonance imaging; prostate cancer

Advances in Vaccines for the Treatment and Prevention of Cancer

edited by

Erika J Crosby

and Emilia Diego

submission deadline 31 Dec 2026 | Viewed by 223 | Submission Open

Keywords: cancer vaccines; neoantigens; tumor-specific antigens; mRNA vaccines; viral vector vaccines; dendritic cell vaccines; immunotherapy; adjuvants; biomarkers of vaccine response; personalized cancer vaccines

Advances in Drug Delivery for Brain Tumors

edited by

Hong-Jian Wei

and Cheng-Chia Wu

submission deadline 31 Dec 2026 | Viewed by 223 | Submission Open

Keywords: brain tumors; glioma; drug delivery; blood–brain barrier; focused ultrasound; convection-enhanced delivery; nanoparticle; exosome; drug conjugate

(This special issue belongs to the Section Cancer Drug Development)

Cancer and the Brain: Brain and Tumor Interplay, the Nervous System's Vulnerabilities and Therapeutic Opportunities

edited by Sylvia C. Kurz

submission deadline 31 Dec 2026 | Viewed by 216 | Submission Open

Keywords: neuro-oncology; primary CNS tumors; secondary CNS tumors; neural networks; glioma cell and neuron crosstalk; brain tumor-related epilepsy; neurotoxicity from cellular immunotherapies

Advances in Diagnostics and Prognostics Tools for Prostate Cancer

edited by

Antonio Celia

, Tommaso Silvestri and Sara Riolo

submission deadline 31 Dec 2026 | Viewed by 210 | Submission Open

Keywords: prostate cancer; prostate biopsy; liquid biopsy; tissue biopsy; biomarkers; staging; risk stratification; prognostic tools

Anal Squamous Cell Carcinoma (SCC)

edited by

Evie H. Carchman

submission deadline 31 Dec 2026 | Viewed by 199 | Submission Open

Keywords: HPV; anal cancer; screening; chemoradiotherapy; immunotherapy

Blood–Brain Barrier and Brain Metastases

edited by Liliana Santos

submission deadline 31 Dec 2026 | Viewed by 196 | Submission Open

Keywords: brain metastasis; blood–brain barrier; tumour microenvironment; cancer immunology; drug delivery; metastatic niche; targeted therapy

(This special issue belongs to the Section Cancer Metastasis)

Biliary Tract Cancer: Challenges and Strategies in Centralizing Care for Rare Tumors

edited by Angela Lamarca

submission deadline 31 Dec 2026 | Viewed by 194 | Submission Open

Keywords: biliary tract cancer; centralization of care; recommendations

Chronic Lymphocytic Leukemia and Indolent B-Cell Lymphomas: Clonal Evolution, Microenvironment, and Immune Remodeling

edited by Franco Fais

submission deadline 31 Dec 2026 | Viewed by 188 | Submission Open

Keywords: chronic lymphocytic leukemia; indolent B-cell lymphomas; clonal evolution; tumor microenvironment; lymph node and bone marrow niche; B-cell receptor signaling; immune dysfunction; T-cell exhaustion; therapy resistance; intratumoral heterogeneity; metabolic reprogramming

Lung Cancer: From Mechanisms of Action and Risk Factors in Disease Onset to Management (2nd Edition)

edited by

Roberto Fabiani

and

Irene Giacchetta

submission deadline 31 Dec 2026 | Viewed by 175 | Submission Open

Keywords: non-small-cell lung cancer (NSCLC); small-cell lung cancer (SCLC); prevention; risk management; mechanisms

Surgical Oncology for Hepato-Pancreato-Biliary Cancer: 2nd Edition

edited by Zaed Z. R. Hamady

submission deadline 31 Dec 2026 | Viewed by 160 | Submission Open

Keywords: pancreatic cancer; liver cancer; liver metastases; surgical oncology; multidisciplinary approach

(This special issue belongs to the Section Clinical Research in Cancer)

Genomics, Epigenomics and Targeted Therapy of Oral Squamous Cell Carcinoma

edited by Mustafa Ozen

submission deadline 31 Dec 2026 | Viewed by 158 | Submission Open

Keywords: oral squamous cell carcinoma; genomics; epigenomics; targeted therapy; biomarkers; tumor microenvironment; precision medicine; translational research

Cancer Without Borders: International Perspectives on Prevention, Diagnosis and Treatment

edited by Km Monirul Islam

submission deadline 31 Dec 2026 | Viewed by 156 | Submission Open

Keywords: global oncology; cancer prevention; early detection; health disparities; cancer care delivery

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Non-Contrast Breast Cancer MRI Screening: Diffusion-Weighted Imaging, DWIBS, and Clinical Implementation

edited by

Taro Takahara

submission deadline 31 Dec 2026 | Viewed by 156 | Submission Open

Keywords: non-contrast breast MRI; breast cancer screening; diffusion-weighted imaging; DWIBS; dense breasts; cancer detection rate; positive predictive value; quality control; remote interpretation; screening implementation

Advances in Multimodal Treatment for Locally Advanced Head and Neck Cancer: Neoadjuvant Therapy, Surgery, and Radiotherapy De-Escalation

edited by

Liang Zhou

and Hongli Gong

submission deadline 31 Dec 2026 | Viewed by 152 | Submission Open

Keywords: head and neck cancer; neoadjuvant therapy; immunotherapy; organ preservation; radiotherapy de‑escalation; predictive biomarkers; prognosis

(This special issue belongs to the Section Cancer Therapy)

Cellular Plasticity in Cancer Progression

edited by Deemesh Oudit

submission deadline 31 Dec 2026 | Viewed by 144 | Submission Open

Keywords: cellular plasticity; epithelial-mesenchymal transition (EMT); cancer stem cells (CSCs); phenotypic plasticity; cell state transitions; lineage plasticity; tumour heterogeneity; dedifferentiation; drug-tolerant persistent cells; epigenetic reprogramming; phenotypic switching; transdifferentiation; cancer cell stemness; tumour microenvironment (TME); therapy resistance (adaptive/reversible resistance); single-cell RNA sequencing

(This special issue belongs to the Section Cancer Pathophysiology)

Advances in Inducement Factors, Precision Diagnostics, and Targeted Therapeutic Strategies for Basal Cell Carcinoma

edited by

Julia Welzel

submission deadline 31 Dec 2026 | Viewed by 144 | Submission Open

Keywords: basal cell carcinoma; inducement factors; precision diagnostics; molecular profiling; targeted therapy; hedgehog signaling pathway; biomarkers; non-invasive imaging; personalized medicine; diagnostic histopathology

Contemporary Pathology of Genitourinary Cancers

edited by Gang Wang and

Charles C. Guo

submission deadline 31 Dec 2026 | Viewed by 130 | Submission Open

Keywords: pathology; genitourinary cancers; diagnostic; molecular; biomarkers

(This special issue belongs to the Section Cancer Pathophysiology)

Carbon-Ion Radiotherapy and Androgen Deprivation Therapy in Prostate Cancer

edited by

Hitoshi Ishikawa

submission deadline 31 Dec 2026 | Viewed by 127 | Submission Open

Keywords: prostate cancer; carbon-ion radiotherapy; androgen deprivation therapy; biochemical relapse-free survival; overall survival; salvage treatment

(This special issue belongs to the Section Cancer Therapy)

Role of PET/CT Imaging in Cancer Diagnosis and Precision Oncology

edited by

Lucia Leccisotti

and

Carmelo Caldarella

submission deadline 31 Dec 2026 | Viewed by 125 | Submission Open

Keywords: PET; cancer diagnosis; oncology; molecular imaging; radiopharmaceuticals; quantitative imaging; radiomics; artificial intelligence; theranostics; precision oncology

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Advancements in Molecular Research of Prostate Cancer (2nd Edition)

edited by

Anait S. Levenson

submission deadline 31 Dec 2026 | Viewed by 124 | Submission Open

Keywords: prostate cancer; molecular targets; tumor heterogeneity; targeted interception and therapies; noninvasive biomarkers; precision oncology

(This special issue belongs to the Section Molecular Cancer Biology)

Novel Targets and Emerging Therapies in T-Cell Lymphomas

edited by Huilai Zhang

submission deadline 31 Dec 2026 | Viewed by 109 | Submission Open

Keywords: T-cell lymphomas; targeted therapy; immunotherapy; epigenetic modulation; clinical trials

(This special issue belongs to the Section Cancer Therapy)

Understanding Drug Resistance in Multiple Myeloma: Biomarkers, Sensitivity and Resistance in MM Cells

edited by Barry A. Paul

submission deadline 31 Dec 2026 | Viewed by 94 | Submission Open

Keywords: biomarkers; multiple myeloma; resistance

(This special issue belongs to the Section Cancer Drug Development)

The Mediastinum—Pandora’s Box

edited by

Cesar A. Moran

submission deadline 1 Jan 2027 | 2 articles | Viewed by 7162 | Submission Open

Keywords: mediastinum; thymus; imaging; surgery; thymoma; germ cell tumors

Evolving Landscape in the Management of Liver Malignancies

edited by Ioannis A. Ziogas and

Dimitrios Moris

submission deadline 1 Jan 2027 | Viewed by 372 | Submission Open

Keywords: liver cancer; hepatocellular carcinoma; cholangiocarcinoma; colorectal liver metastasis; liver resection; liver transplantation; transplant oncology; locoregional therapies; immunotherapy; molecular profiling

The Function of the MYC Network in Normal and Neoplastic Tissues

edited by

Edward Prochownik

and Dean W. Felsher

submission deadline 1 Jan 2027 | Viewed by 206 | Submission Open

Keywords: aging; cancer; enhancers; ribosomes; transcription; tumor metabolism; tumor suppressors; Warburg effect

(This special issue belongs to the Section Molecular Cancer Biology)

Nursing and Supportive Care for Cancer Survivors

edited by

Michela Piredda

submission deadline 2 Jan 2027 | 4 articles | Viewed by 7398 | Submission Open

Keywords: cancer survivorship; oncology nursing; symptom management; quality of life; supportive care; psycho-existential distress; pain catastrophizing; palliative care; caregiver support; advanced cancer; patient-centred care

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Systematic Reviews and Meta-Analyses on Skin Cancer

edited by

Stan N. Tolkachjov

submission deadline 5 Jan 2027 | Viewed by 287 | Submission Open

Keywords: skin cancer; dermatologic oncology; Mohs micrographic surgery; cutaneous oncology; systematic review

Nutrition in Cancer Care: From Generalized to Personalized Adjunctive Therapy

edited by

Mitsuyoshi Urashima

submission deadline 6 Jan 2027 | 4 articles | Viewed by 3329 | Submission Open

Keywords: anthropometry; body mass index (BMI); body surface area (BSA); personalized medicine; therapeutic drug monitoring (TDM); pharmacokinetics; nutritional status; chemotherapy optimization; vitamin D; adjunctive therapy

The Advances in Proton Therapy in Head-and-Neck Cancers

edited by

Nancy Lee

and Edward Christopher Dee

submission deadline 8 Jan 2027 | Viewed by 632 | Submission Open

Keywords: proton therapy; head-and-neck cancer; clinical outcomes; toxicity reduction; multinational studies; reirradiation; skull base tumors; salivary gland cancers; prospective and retrospective cohorts

(This special issue belongs to the Section Cancer Therapy)

Tumor Microenvironment in Ovarian Cancer Progression, Dissemination, Recurrence: Biology and Therapeutic Opportunities

edited by

Ralf-Peter Czekay

Paul J. Higgins

and

Dong-Joo Cheon

submission deadline 10 Jan 2027 | 1 articles | Viewed by 588 | Submission Open

Keywords: transperitoneal carcinomatosis; malignant ascites; chemoresistance; metabolic adaptations; regulation of immune response; tumor–stroma interaction; tumor–peritoneal interaction

(This special issue belongs to the Section Tumor Microenvironment)

Contemporary Advances in Esophageal and Upper Gastrointestinal Cancer Management

edited by

Giovanni Maria Garbarino

and Carlo Castoro

submission deadline 10 Jan 2027 | Viewed by 158 | Submission Open

Keywords: esophageal surgery; gastric surgery; upper gastrointestinal cancer; minimally invasive surgery; robotic surgery; artificial intelligence; radiomics; neoadjuvant therapy; surgical quality assessment; fluorescence-guided surgery

(This special issue belongs to the Section Methods and Technologies Development)

Perioperative Management and Anesthetic Strategies for Improving Cancer Prognosis

edited by

Juan P. Cata

Lucillia Bezu

and

Nicolas Villablanca Uribe

submission deadline 13 Jan 2027 | 1 articles | Viewed by 1050 | Submission Open

Keywords: perioperative care; anesthesia; cancer; oncological outcomes

Advances in Hodgkin Lymphoma (HL)

edited by

Antonino Carbone

submission deadline 15 Jan 2027 | 4 articles | Viewed by 13532 | Submission Open

Keywords: classic Hodgkin lymphoma; diagnostic challenges; tumour microenvironment; variability in disease extent; TME-targeted therapies; personalized treatment; relapsed/refractory cHL

(This special issue belongs to the Section Cancer Pathophysiology)

Lung Cancer—Advances in Therapy and Prognostic Prediction

edited by Chinmay T. Jani and Estelamari Rodríguez

submission deadline 15 Jan 2027 | 7 articles | Viewed by 7805 | Submission Open

Keywords: lung cancer; biomarkers; targeted therapies; immunotherapy; precision medicine

(This special issue belongs to the Section Cancer Biomarkers)

Penile Cancer and Rare Urogenital Malignancies: From Biology to Clinical Management

edited by

Mateusz Czajkowski

and Marcin Matuszewski

submission deadline 15 Jan 2027 | 4 articles | Viewed by 7634 | Submission Open

Keywords: penile cancer; urethral carcinoma; upper tract urothelial carcinoma; rare urogenital tumors; surgical management; systemic therapy; epidemiology

New Insights into Thymic Tumors

edited by Till Ploenes

submission deadline 15 Jan 2027 | 2 articles | Viewed by 2060 | Submission Open

Keywords: thymic tumors; thymic carcinoma; thymomas; new daignostic and therapeutic approaches; myasthenia gravis

Nanocarriers as an Emerging Platform for Cancer Therapy

edited by

Andrea Markus

and Fernanda Ramos-Gomes

submission deadline 15 Jan 2027 | 1 articles | Viewed by 1774 | Submission Open

Keywords: nanoparticles; cancer therapy; nanomedicine; theranostics; chemotherapy; nanocarriers; drug delivery; nanotechnology

(This special issue belongs to the Section Cancer Therapy)

Flow Cytometry in Acute Leukemia: From Diagnosis to Disease Monitoring

edited by

Donatella Raspadori

and

Paola Pacelli

submission deadline 15 Jan 2027 | 2 articles | Viewed by 1584 | Submission Open

Keywords: acute leukemia; ALL; AML; flow cytometry; NGF; leukemia stem cells (LSCs; minimal residual disease (MRD)

(This special issue belongs to the Section Methods and Technologies Development)

Mass Spectrometry and Cancers

edited by

Rita Casadonte

and

Kristina Schwamborn

submission deadline 15 Jan 2027 | 1 articles | Viewed by 980 | Submission Open

Keywords: cancer; biomolecular; mass spectrometry

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Advancing CAR-T Cell Therapy: The Next Evolution in Breast Cancer Treatment

edited by

Nethaji Muniraj

and

Arun Dharmarajan

submission deadline 15 Jan 2027 | Viewed by 910 | Submission Open

Keywords: CAR-T cell therapy; breast cancer; triple-negative breast cancer (TNBC); HER2-positive breast cancer; tumor microenvironment; immunotherapy

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Three-Dimensional In Vitro Modeling for the Study of Epithelial Cancers

edited by

Sherif M. Karam

and George Wai Cheong Yip

submission deadline 15 Jan 2027 | Viewed by 484 | Submission Open

Keywords: 3D cancer model; 3D cancer stem cell culture; 3D tumor invasion model; cancer-on-a-chip; cancer spheroids; carcinogenesis organoid model; bioprinted cancer tissue; microfluidic platform for cancer; scaffold-based cancer model

(This special issue belongs to the Section Methods and Technologies Development)

AI and Machine Learning in Cancer Multi-Omics: Identification of Biomarkers, Disease-Related Processes and Drug Targets

edited by Graham Ball

submission deadline 15 Jan 2027 | Viewed by 409 | Submission Open

Keywords: artificial intelligence; machine learning; multi-omics integration; biomarker discovery; precision oncology; drug target identification; computational cancer biology

(This special issue belongs to the Section Methods and Technologies Development)

Pancreatic Cancer: Genomics, Therapy and Survival

edited by Hisanobu Ogata

submission deadline 15 Jan 2027 | Viewed by 365 | Submission Open

Keywords: pancreas; cancer; treatment; oncolytic virus; stromal cell; cancer-associated fibroblast (CAF)

(This special issue belongs to the Section Cancer Therapy)

Radiotherapy in Gynecological Cancer: State of the Art (2nd Edition)

edited by

Àngeles Rovirosa

and

Meritxell Arenas

submission deadline 15 Jan 2027 | Viewed by 255 | Submission Open

Keywords: interventional radiotherapy; brachytherapy techniques; gynecological oncology; educational gynecology; gynecological cancer

(This special issue belongs to the Section Cancer Therapy)

Improving the Quality of Life in Patients with Gynecological Cancer

edited by Vasilios Pergialiotis

submission deadline 20 Jan 2027 | 2 articles | Viewed by 14318 | Submission Open

Keywords: gynecologic oncology; minimal invasive surgery; ovarian cancer; ERAS protocol; perioperative care; immunonutrition; cervical cancer

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Feature Review Papers on Cancer Epidemiology, Disparities, and Prevention

edited by Adam Barsouk

submission deadline 20 Jan 2027 | 2 articles | Viewed by 3893 | Submission Open

Keywords: epidemiology; disparities; oncology; cancer; prevention

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Advances in Molecules and Drug Delivery Systems in Brain Tumors

edited by Horng-Jyh Harn and Ching-Ann Liu

submission deadline 27 Jan 2027 | Viewed by 101 | Submission Open

Keywords: brain tumors; blood–brain barrier; drug delivery systems; nanoparticles; molecular targets; targeted therapy; nanomedicine; combination therapy; translational research; biomarkers

(This special issue belongs to the Section Cancer Drug Development)

Displaying special issue 601-650 on page 13 of 22.

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