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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Cytoreduction in Gynecologic Oncology
edited by Sabrina Piedimonte
submission deadline 14 Aug 2026 | Viewed by 4 | Submission Open
Keywords: cytoreduction; ovarian cancer; endometrial cancer; minimally invasive surgery; AI
(This special issue belongs to the Section Cancer Therapy)
Recent Updates and Future Perspectives on Anti-Cancer Agents submission deadline 15 Aug 2026 | 2 articles | Viewed by 2748 | Submission Open
Keywords: cancer; anti-cancer agents; targeted therapy; drug resistance; therapeutic agents; natural compounds; combination therapy; nanotherapy; translational therapy; immunotherapy
(This special issue belongs to the Section Cancer Drug Development)
Rare Genitourinary Cancers submission deadline 15 Aug 2026 | Viewed by 160 | Submission Open
Keywords: rare genitourinary tumors; penile cancer; testicular cancer; urethral cancer; adrenal cancer; variant histology; upper tract urothelial carcinoma; extramammary Paget’ s disease; urologic oncology; rare cancers
(This special issue belongs to the Section Clinical Research of Cancer)
Immunotherapy for Hematologic Malignancies
edited by Rajesh Ramakrishnan Nair
submission deadline 15 Aug 2026 | Viewed by 136 | Submission Open
Keywords: immune evasion; immunotherapy; CAR-T cell therapy; BiTEs; immunomodulators; checkpoint; inhibitors; bone marrow microenvironment; refractory/relapsed; drug resistance; gene editing
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Clinical Applications of Advanced MRI Technologies for Cancers
edited by
submission deadline 15 Aug 2026 | Viewed by 98 | Submission Open
Keywords: advanced MRI techniques; multiparametric imaging; quantitative biomarkers; artificial intelligence; treatment response assessment; precision oncology; radiomics; cancer diagnosis; functional imaging; molecular imaging
(This special issue belongs to the Section Methods and Technologies Development)
Advances in Immunotherapy for Acute Myeloid Leukemia
edited by
submission deadline 15 Aug 2026 | Viewed by 4 | Submission Open
Keywords: acute myeloid leukemia; immunotherapy; immune response; T-cell; cellular therapies; immune checkpoint inhibitors; treatment
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Cancer and Solid Organ Transplantation
edited by
submission deadline 15 Aug 2026 | Viewed by 2 | Submission Open
Keywords: post-transplant malignancy; transplant oncology; liver transplantation; multidisciplinary care; artificial intelligence; precision medicine; immunosuppression; transplant immunology; cancer immunology; cancer diagnosis
(This special issue belongs to the Section Transplant Oncology)
Rare Cancers, Diagnostic Challenges and Personalized Therapeutic Approaches in the 21st Century (2nd Edition)
edited by
submission deadline 20 Aug 2026 | 2 articles | Viewed by 2567 | Submission Open
Keywords: rare cancer; biology; diagnosis; classification; personalized therapeutics; markers
(This special issue belongs to the Section Cancer Therapy)
Advances in Clinical, Diagnostic and Neurosurgical Management in Pediatric Neuro-Oncology
edited by and Michael Levy
submission deadline 20 Aug 2026 | Viewed by 184 | Submission Open
Keywords: neuro-oncology; brain tumors; neuroradiology; proton therapy; pediatric; neurosurgery; treatment; chemotherapy; targeted agents; molecular subtypes; immunotherapy; late effects; radiation therapy
(This special issue belongs to the Section Pediatric Oncology)
Socio-Demographic Factors and Cancer Research: 2nd Edition
edited by and Amanda N. Goldin
submission deadline 20 Aug 2026 | Viewed by 138 | Submission Open
Keywords: socio-economic disparity; cancer delivery; cancer survival; metastatic cancer; culture-specific cancer outcomes; AI; machine learning
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Advances in Surgery for Endocrine Cancers
edited by Michael Bouvet and Eren Berber
submission deadline 20 Aug 2026 | Viewed by 85 | Submission Open
Keywords: thyroid cancer; thyroid surgery; hyperparathyroidism; adrenal tumors; adrenal surgery; pancreatic neuroendocrine tumors; fluorescence guided surgery; intraoperative imaging; surgical navigation; technological innovation
(This special issue belongs to the Section Methods and Technologies Development)
Pain and Palliative Care in Patients with Cancers submission deadline 20 Aug 2026 | Viewed by 71 | Submission Open
Keywords: cancer pain; palliative care; opioid tolerance
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Multidisciplinary Strategies in Challenging Neuro-Oncological Surgery
edited by
submission deadline 20 Aug 2026 | Viewed by 30 | Submission Open
Keywords: neuro-oncology; surgery; awake craniotomy; intraoperative MRI; MRI navigation system; intraoperative photodynamic diagnosis/therapy; intraoperative pathological diagnosis
(This special issue belongs to the Section Clinical Research of Cancer)
Diagnostic Biomarkers in Cancers Study
edited by Zejuan Li and
submission deadline 21 Aug 2026 | 4 articles | Viewed by 7429 | Submission Open
Keywords: cancer; diagnostics; biomarker
(This special issue belongs to the Section Cancer Biomarkers)
Contemporary Diagnosis and Management of Prostate Cancer (2nd Edition)
edited by Thomas Jang
submission deadline 22 Aug 2026 | 1 articles | Viewed by 1576 | Submission Open
Keywords: prostate cancer; diagnosis; management; radical prostatectomy; biomarkers
(This special issue belongs to the Section Cancer Therapy)
Clinical Studies of Colorectal Cancer Surgery
edited by and Ioannis Baloyiannis
submission deadline 25 Aug 2026 | Viewed by 41 | Submission Open
Keywords: colon; rectal; cancer; clinical; trials; evidence; open; laparoscopic; robotic; surgery
(This special issue belongs to the Section Clinical Research of Cancer)
Contemporary Advances and Challenges in Multimodal Management of Gastric Cancer
edited by Karol Rawicz-Pruszyński and Zuzanna Pelc
submission deadline 25 Aug 2026 | Viewed by 3 | Submission Open
Keywords: gastric cancer; multimodal therapy; perioperative chemotherapy; immunotherapy; minimally invasive surgery/robotic gastrectomy; surgical escalation and de-escalation; conversion surgery; patient selection/prognostic factors; biomarkers (her2; pd-l1; msi; ctdna); perioperative nutrition/eras
(This special issue belongs to the Section Cancer Therapy)
Modern Approach to Oral Cancer submission deadline 30 Aug 2026 | 11 articles | Viewed by 48629 | Submission Open
Keywords: oral cancer; neoplasm; oral surgery oncogenesis; dentistry oral health
(This special issue belongs to the Section Cancer Therapy)
Pathology of Acute Myeloid Leukemia (AML)
edited by Olga K. Weinberg
submission deadline 30 Aug 2026 | Viewed by 1271 | Submission Open
(This special issue belongs to the Section Cancer Pathophysiology)
Long-Term Health Outcomes and Quality of Life in Survivors of Childhood Cancer submission deadline 30 Aug 2026 | 2 articles | Viewed by 1175 | Submission Open
Keywords: acute lymphoblastic leukemia; brain tumors; childhood cancer survivors; pollutants; environment; quality of life; nutrition; chemotherapy; air and water purification
(This special issue belongs to the Section Pediatric Oncology)
Pathology of Gynecological Cancers (2nd Edition)
edited by
submission deadline 30 Aug 2026 | Viewed by 266 | Submission Open
Keywords: endometrial cancer; ovarian cancer; vulvar cancer; cervical cancer; vaginal cancer
(This special issue belongs to the Section Cancer Pathophysiology)
Proteometabolomics in Cancer submission deadline 30 Aug 2026 | Viewed by 154 | Submission Open
Keywords: proteomics; metabolomics; cancer biology; tumor microenvironment; biomarkers; therapeutics
(This special issue belongs to the Section Molecular Cancer Biology)
Robotic and Laparoscopic Surgery in Colorectal Cancer: Current Trends and Future Perspectives
edited by , Quentin Denost and Barbara Noiret
submission deadline 30 Aug 2026 | Viewed by 150 | Submission Open
Keywords: robotic surgery; laparoscopic surgery; colorectal cancer; minimally invasive surgery; comparative outcomes (perioperative; oncologic; functional); conversion rates; open surgery; learning curve and surgical training; cost‐effectiveness and health economics; technological innovations (e.g.; AI; imaging; instrumentation); quality of life and long‐term patient‐reported outcomes
(This special issue belongs to the Section Cancer Therapy)
Tumor Suppressor and Targeted Therapy in Hepatocellular Carcinoma: From Diagnosis to Treatment (2nd Edition)
edited by , and I-Cheng Lee
submission deadline 30 Aug 2026 | Viewed by 104 | Submission Open
Keywords: tumor suppressor; targeted therapy; hepatocellular carcinoma
(This special issue belongs to the Section Tumor Microenvironment)
Neoantigen Vaccines for Cancer Therapy
edited by Takashi Morisaki
submission deadline 30 Aug 2026 | Viewed by 104 | Submission Open
Keywords: neoantigens; vaccine; dendritic cells; cancer; immunotherapy; priming; CTL; helper T cells
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Research on Fluorescence-Guided Surgery in Cancer Treatment (2nd Edition)
edited by
submission deadline 30 Aug 2026 | Submission Open
Keywords: fluorescence-guided surgery; fluorescent agents; tumor fluorescence; tumor margin detection; residual tumor assessment; glioma surgery; fluorescein sodium; 5-aminolevulinic acid; confocal endomicroscopy; Raman spectroscopy
(This special issue belongs to the Section Cancer Therapy)
Challenges and Opportunities in Developing Therapies for Drug Resistance and Other Malignancies
edited by
submission deadline 30 Aug 2026 | Submission Open
Keywords: cancer; chemotherapy; multidrug resistance; innovative therapy
Gastrointestinal Malignancy: Epidemiology and Risk Factors
edited by Patrick Okolo and Chengu Niu
submission deadline 31 Aug 2026 | 8 articles | Viewed by 34199 | Submission Open
Keywords: gastrointestinal cancer; epidemiology; risk factors; molecular markers; genetic factors; therapeutic advancements; prevention strategies; public health; interdisciplinary approaches; clinical impact
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Advancements in “Cancer Biomarkers” for 2025–2026 submission deadline 31 Aug 2026 | 11 articles | Viewed by 18193 | Submission Open
Keywords: RNA biomarkers; miRNA biomarkers; DNA biomarkers; cell-free DNA (cfDNA); protein biomarkers; metabolomic biomarkers; mutational biomarkers; circulating tumor cells (CTCs); tumor-derived extracellular vesicle (tEV) biomarkers; cellular biomarkers; imaging biomarkers; clinical biomarkers; biomarkers of drug response; biomarkers of genetic predisposition to cancer; epigenetic biomarkers; biomarkers of cancer outcomes; mass spectrometry; next-generation sequencing (NGS); flow cytometry; positron emission tomography (PET); computed tomography (CT); magnetic resonance imaging (MRI); X-rays; ultrasound; electrocardiography (ECG/EKG); endoscopy; biopsy; pulmonary function tests (PFTs); histopathology; cytopathology; immunohistochemistry (IHC); in situ hybridization (ISH); fluorescence in situ hybridization (FISH); liquid biopsy; electron microscopy; digital pathology and image analysis
(This special issue belongs to the Section Cancer Biomarkers)
Advancing Horizons in Colorectal Surgery: Innovative Approaches and Outcomes
edited by Petros I. Bangeas and Vasileios N. Papadopoulos
submission deadline 31 Aug 2026 | 4 articles | Viewed by 18091 | Submission Open
Keywords: colorectal surgery; postoperative pain; surgical site infections; anastomotic leaks; minimally invasive techniques; robotic surgery
(This special issue belongs to the Section Cancer Therapy)
Feature Review Paper Special Issue in Section Molecular Cancer Biology
edited by
submission deadline 31 Aug 2026 | 3 articles | Viewed by 9647 | Submission Open
Keywords: molecular biology; cell biology; cancer; tumor; cancer cell
(This special issue belongs to the Section Molecular Cancer Biology)
Prevention, Early Detection, and Surgical Oncology in Hepatocellular Carcinoma, Pancreatic Cancer, and Gastrointestinal Cancer
edited by and
submission deadline 31 Aug 2026 | 4 articles | Viewed by 5853 | Submission Open
Keywords: early image detection in cancer; biomarker of cancer; surgical treatment; gastrointestinal cancer
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Cancer Stem Cells: The Origin of Tumor Relapse and Metastasis submission deadline 31 Aug 2026 | 3 articles | Viewed by 5083 | Submission Open
Keywords: metastasis; cancer stem cell; tumor microenvironment; tumor heterogeneity; plasticity; immune evasion; therapeutic resistance
(This special issue belongs to the Section Molecular Cancer Biology)
The Genetic Analysis and Clinical Therapy in Lung Cancer: 2nd Edition
edited by and Frullanti Elisa
submission deadline 31 Aug 2026 | 1 articles | Viewed by 4130 | Submission Open
Keywords: lung cancer; biomarkers; genetic variants; innovative technologies; targeted therapy; immunotherapy; personalized therapy; survival; liquid biopsy pharmacogenomics
(This special issue belongs to the Section Cancer Therapy)
CAR T-Cell Therapy and Multiple Myeloma
edited by Jo Caers
submission deadline 31 Aug 2026 | 1 articles | Viewed by 964 | Submission Open
Keywords: multiple myeloma; CAR-T immunotherapy; toxicity; efficacy; tumor models; safety
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Tumor Microenvironment in Cancer Therapies: Supportive or Hostile? submission deadline 31 Aug 2026 | 1 articles | Viewed by 960 | Submission Open
Keywords: tumor microenvironment; protumor effects; antitumor effects; immune cells; stromal cells; extracellular matrix; cancer therapies
(This special issue belongs to the Section Tumor Microenvironment)
New Advances and Approaches in Thyroid Cancer
edited by and José Manuel Rodríguez
submission deadline 31 Aug 2026 | 1 articles | Viewed by 795 | Submission Open
Keywords: thyroid cancer; medullary thyroid cancer; papillary thyroid cancer; follicular thyroid cancer; poorly differentiated thyroid tumours; novel approaches; prognostic biomarkers; risk stratification
(This special issue belongs to the Section Cancer Therapy)
Emergencies in Gastrointestinal Surgical Oncology submission deadline 31 Aug 2026 | Viewed by 571 | Submission Open
Keywords: surgical oncology; emergencies; emergency surgery; acute care surgery; palliation; futility in surgery
(This special issue belongs to the Section Clinical Research of Cancer)
Hereditary Cancer: State of the Art
edited by Joanne Ngeow, Jianbang Chiang and
submission deadline 31 Aug 2026 | Viewed by 212 | Submission Open
Keywords: hereditary cancer syndromes; inherited cancers; cancer genetics and genomics; germline variants; surveillance
(This special issue belongs to the Section Cancer Pathophysiology)
Hypoxia-Targeting Strategies to Improve Cancer Therapy Outcomes
edited by Roben Gieling and Ayse Latif
submission deadline 31 Aug 2026 | Viewed by 157 | Submission Open
Keywords: tumor hypoxia; cancer therapy resistance; hypoxia-targeted therapy; hypoxia-inducible factors (HIFs); hypoxia-activated prodrugs; oxygen-modifying agents; combination therapy; precision drug delivery; tumor microenvironment; translational cancer research
(This special issue belongs to the Section Cancer Therapy)
CAR T Cell Therapy in Cancer: Progress and Challenges Across Solid and Hematologic Malignancies
edited by John F. Marshall and Lauren C. Cutmore
submission deadline 31 Aug 2026 | Viewed by 126 | Submission Open
Keywords: CAR-T cell therapy; adoptive cell therapy; immunotherapy; antigen escape; solid tumor; hematologic malignancies
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Clinical Treatment and Outcomes of Gastrointestinal Cancer
edited by Mary Linton Peters
submission deadline 31 Aug 2026 | Viewed by 114 | Submission Open
Keywords: gastrointestinal cancer; ctDNA; chemotherapy; immunotherapy; financial toxicity; clinical trial participation
(This special issue belongs to the Section Clinical Research of Cancer)
Acute Myeloid Leukemia in Adults (2nd Edition) submission deadline 31 Aug 2026 | Viewed by 113 | Submission Open
Keywords: acute myeloid leukemia; molecular biology; treatment landscape; resistance mechanisms
(This special issue belongs to the Section Clinical Research of Cancer)
Human Carcinogens—Chemical Agents, Occupational Exposure and Health Impact
edited by Jun-Pyo Myong
submission deadline 31 Aug 2026 | Viewed by 111 | Submission Open
Keywords: occupational exposure; chemical carcinogens; risk assessment; epidemiology; biomarkers; exposure assessment; preventive strategies; workplace safety; occupational health; regulatory measures
(This special issue belongs to the Section Infectious Agents and Cancer)
The Unseen Burden: Incidence and Outcomes of Infections in Leukemia submission deadline 31 Aug 2026 | Viewed by 95 | Submission Open
Keywords: infection management; infectious risk; antimicrobial therapy; antimicrobial prophylaxis
(This special issue belongs to the Section Infectious Agents and Cancer)
Advances in the Early Diagnosis and Treatment of Gastric Cancer (2nd Edition)
edited by Sharona B. Ross
submission deadline 31 Aug 2026 | Viewed by 88 | Submission Open
Keywords: gastric cancer; tumor resection; liver tumors
(This special issue belongs to the Section Cancer Therapy)
Advances in the Multimodal Management of Pancreatic Ductal Adenocarcinoma submission deadline 31 Aug 2026 | Viewed by 84 | Submission Open
Keywords: pancreatic ductal adenocarcinoma (PDAC); multimodal approach; systemic therapy; radiotherapy; targeted strategies; neoadjuvant therapy; adjuvant therapy
(This special issue belongs to the Section Cancer Therapy)
Early Detection and Strategies for Overcoming Therapy Resistance in Lung Cancer and Mesothelioma
edited by
submission deadline 31 Aug 2026 | Viewed by 79 | Submission Open
Keywords: lung cancer; mesothelioma; screening; biomarker; molecular diagnostics; resistance
(This special issue belongs to the Section Cancer Therapy)
Wnt Signaling Pathway in Cancer Immunotherapy
edited by and
submission deadline 31 Aug 2026 | Viewed by 67 | Submission Open
Keywords: Wnt signaling; immunotherapy; immune cells; macrophages; T-cell; CART cells; stromal cells; tumor microenvireonment; cancers; cancer stem cells
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
mTOR Signaling in Cancer
edited by
submission deadline 31 Aug 2026 | Viewed by 50 | Submission Open
Keywords: mTOR; cancer; cell signaling; pathway addiction; tumor metabolism; glycolysis; autophagy; apoptosis; rapamycin
(This special issue belongs to the Section Molecular Cancer Biology)
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