Liquid Biopsy in Cancer

Dear Colleagues, 

Precision medicine is becoming the new paradigm in healthcare as it enables treatment optimization, a potential reduction in side effects, and better resources allocation. Liquid biopsy is the cornerstone of this revolution since it provides real-time prognostic and predictive information for advanced cancer patients without the analytical and procedural drawbacks of tissue biopsy.

Several technologies are comprised under the umbrella term of “liquid biopsy”, each with its strengths and peculiarities. In particular, circulating tumor DNA (ctDNA) together with circulating tumor cells (CTCs) and microvesicles are gaining momentum as promising markers for early disease characterization and longitudinal monitoring for resistance detection.

This Special Issue is aimed at summarizing both analytical developments and clinical evidence regarding the application of liquid biopsy across the major cancer types, with a special focus on its clinical utility and how its deployment will ultimately lead to the growing personalization of cancer care.

Prof. Fabio Puglisi
Dr. Lorenzo Gerratana
Guest Editors

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