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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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New Insights into Prostate Cancer Radiotherapy
edited by
submission deadline 10 Feb 2026 | 6 articles | Viewed by 13903 | Submission Open
Keywords: prostate cancer; radiotherapy; radiation therapy
(This special issue belongs to the Section Cancer Therapy)
New Insights into Cancer Radiotherapy submission deadline 10 Feb 2026 | 2 articles | Viewed by 2248 | Submission Open
Keywords: radiotherapy; X-rays; gamma rays; external beam radiation therapy; brachytherapy; palliative care; intensity-modulated radiotherapy (IMRT); stereotactic body radiotherapy (SBRT); proton therapy
(This special issue belongs to the Section Cancer Therapy)
Recent Developments in the Field of Radiotherapy Treatment for Lung Cancer
edited by Ioannis C. Maroulis
submission deadline 10 Feb 2026 | 1 articles | Viewed by 1566 | Submission Open
Keywords: lung cancer; radiotherapy; non-small-cell lung cancer (NSCLC)
(This special issue belongs to the Section Cancer Therapy)
Transforming Liver Cancer Care: From Molecular Understanding to Novel Therapeutic Strategies
edited by
submission deadline 10 Feb 2026 | 1 articles | Viewed by 445 | Submission Open
Keywords: liver cancer; molecular research; biomarkers; targeted therapy; translational research
(This special issue belongs to the Section Tumor Microenvironment)
Advances in Surgical Treatment of Gynecological Cancers
edited by , Joanna P. Kacperczyk-Bartnik and
submission deadline 14 Feb 2026 | 2 articles | Viewed by 2555 | Submission Open
Keywords: gynecological oncology; image-guided surgery; lymphadenectomy; minimally invasive surgery; ovarian cancer surgery; patient outcomes; perioperative care; precision surgery; radical hysterectomy; robotic-assisted surgery; surgical oncology
(This special issue belongs to the Section Cancer Therapy)
Metronomic Chemotherapy in Female Cancers
edited by
submission deadline 14 Feb 2026 | 1 articles | Viewed by 1717 | Submission Open
Keywords: metronomic chemotherapy; female cancers; anti-tumor mechanisms; clinical trials and outcomes; combination therapies
(This special issue belongs to the Section Cancer Therapy)
New and Emerging Strategies for Targeting Genomic Instability and Overcoming Drug Resistance in Lung Cancer
edited by Kelsie L. Thu
submission deadline 15 Feb 2026 | 5 articles | Viewed by 16298 | Submission Open
Keywords: lung cancer; genomic instability; drug resistance; treatment strategy; targeted therapy
(This special issue belongs to the Section Cancer Therapy)
New Strategies in Diagnosis and Treatments for Brain Tumors: 2nd Edition
edited by Sven Rainer Kantelhardt
submission deadline 15 Feb 2026 | 4 articles | Viewed by 15686 | Submission Open
Keywords: glioma; brain tumor; molecular guided therapy; personal medicine; radiomics; digital analysis; artificial intelligence; intraoperative imaging; surgical resection
(This special issue belongs to the Section Cancer Therapy)
Advances in Esophageal Cancer
edited by Sacheen Kumar
submission deadline 15 Feb 2026 | 4 articles | Viewed by 6798 | Submission Open
Keywords: esophageal adenocarcinoma; esophageal squamous cell carcinoma; long-term survival; biomarkers; disease surveillance; treatment response
(This special issue belongs to the Section Cancer Therapy)
Neoadjuvant Therapy in Hepatopancreatobiliary Malignancies: Current Trends and Future Directions submission deadline 15 Feb 2026 | 1 articles | Viewed by 2374 | Submission Open
Keywords: neoadjuvant therapy; hepatopancreatobiliary malignancies; hepatocellular carcinoma; pancreatic cancer; cholangiocarcinoma; chemotherapy; radiotherapy; immunotherapy; targeted therapies; personalized treatment
(This special issue belongs to the Section Cancer Therapy)
Oligometastases Hypothesis to Advancing New Perspectives on Cancer: Oligo-Reurrence submission deadline 15 Feb 2026 | 1 articles | Viewed by 2084 | Submission Open
Keywords: oligometastases; oligo-recurrence; sync-oligometastases
(This special issue belongs to the Section Cancer Metastasis)
The Elderly Multiple Myeloma Patient in the Era of Quad Therapy and CAR-T Cells
edited by James J. Ignatz-Hoover and Koen Van Besien
submission deadline 15 Feb 2026 | 1 articles | Viewed by 1572 | Submission Open
Keywords: multiple myeloma; quad therapy; CAR-T; elderly
(This special issue belongs to the Section Cancer Therapy)
Advances in Precision Medicine: Targeting Known and Emerging Oncogenic Targets in Lung Cancer (2nd Edition)
edited by
submission deadline 15 Feb 2026 | Viewed by 194 | Submission Open
Keywords: precision oncology; lung cancer; oncogenic target; targeted therapy; biomarker; diagnosis
(This special issue belongs to the Section Molecular Cancer Biology)
Epigenetics and Non-Coding RNAs in Multiple Myeloma
edited by
submission deadline 15 Feb 2026 | Viewed by 136 | Submission Open
Keywords: multiple myeloma; epigenetics; non-coding RNAs; microRNAs (miRNAs); long non-coding RNAs (lncRNAs); circular RNAs (circRNAs); DNA methylation; histone modifications; drug resistance; precision medicine
(This special issue belongs to the Section Cancer Biomarkers)
Genetic Changes in CNS Neoplasms
edited by Kimberly Bojanowski Hoang
submission deadline 15 Feb 2026 | Viewed by 96 | Submission Open
Keywords: primary brain tumor; secondary brain tumor; metastasis; glioma; genetics; genomics; CNS; neoplasms
(This special issue belongs to the Section Cancer Biomarkers)
Prognostic and Predictive Biomarkers in Ovarian Cancer
edited by Jayakumar Nair
submission deadline 15 Feb 2026 | Viewed by 31 | Submission Open
Keywords: molecular biomarkers; clinical biomarkers; immune biomarkers; genetic biomarkers; ovarian cancer; personalized medicine
(This special issue belongs to the Section Cancer Biomarkers)
Diagnosis, Treatment and Prevention of Gastrointestinal Cancer (2nd Edition)
edited by and Min Gi
submission deadline 18 Feb 2026 | 2 articles | Viewed by 9447 | Submission Open
Keywords: cancer; screening; diagnosis; anti-cancer; drugs; mechanisms of carcinogenesis; chemopreventive agents
(This special issue belongs to the Section Cancer Therapy)
Gaps in Cancer Cachexia Research
edited by Jose M. Garcia and
submission deadline 20 Feb 2026 | 3 articles | Viewed by 10826 | Submission Open
Keywords: cancer cachexia; physical function; innovative models; rehabilitation; patient-reported outcomes; gender; aging; skeletal muscle; brain; adipose tissue
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Epigenetic Regulation in Cancers
edited by and
submission deadline 20 Feb 2026 | 3 articles | Viewed by 10576 | Submission Open
Keywords: oncogenes; tumor suppressor genes; tumor microenvironment; cancer therapy; DNA and histone methylation; microRNAs; epitranscriptomics; RNA modifications; modifying proteins
(This special issue belongs to the Section Tumor Microenvironment)
Quality of Life and Side Effects Management in Cancer Treatment (3rd Edition)
edited by
submission deadline 20 Feb 2026 | 4 articles | Viewed by 8184 | Submission Open
Keywords: cancer treatment adverse events; quality of life in cancer patients; chemotherapy adverse events; target therapy adverse events; immunotherapy adverse events; hormonotherapy adverse events; chemotherapy-induced nausea and vomiting; cancer pain
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Chronic Intestinal Inflammation and Cancers (2nd Edition)
edited by Livia Biancone and David Laharie
submission deadline 20 Feb 2026 | 3 articles | Viewed by 5080 | Submission Open
Keywords: colorectal cancer; chronic inflammation; inflammatory bowel disease; inflammation-associated dysplasia; outcomes; cancer molecular pathways
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Ultrasonography for Pancreatobiliary Cancer
edited by
submission deadline 20 Feb 2026 | 3 articles | Viewed by 5027 | Submission Open
Keywords: endoscopic ultrasonography; abdominal ultrasonography; early diagnosis project; screening; EUS-FNA; interventional EUS; enhancement EUS; EUS-RFA
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Multiple Myeloma: Recent Advances in Diagnosis, Analysis and Therapeutic Management: 2nd Edition submission deadline 20 Feb 2026 | 1 articles | Viewed by 3037 | Submission Open
Keywords: multiple myeloma (MM); hematologic malignancies; next-generation sequencing; heterogeneous disease; tumor heterogeneity; genomic landscape; outcomes; novel treatments; clinical trial
(This special issue belongs to the Section Cancer Therapy)
Breast Cancer Biomarkers and Clinical Translation: 2nd Edition
edited by and Carmine De Angelis
submission deadline 20 Feb 2026 | 2 articles | Viewed by 2020 | Submission Open
Keywords: breast cancer diagnosis; cancer risk; cell reprogramming; biomarkers; resistance; precision therapy
(This special issue belongs to the Section Cancer Biomarkers)
Advanced Surgical Modalities in Breast Cancer Treatment
edited by Jan Žatecký
submission deadline 20 Feb 2026 | 1 articles | Viewed by 1153 | Submission Open
Keywords: breast cancer surgery; breast cancer localization; breast conserving surgery; mastectomy; oncoplastic surgery; axillary lymph node staging; sentinel lymph node biopsy; targeted axillary dissection
(This special issue belongs to the Section Clinical Research of Cancer)
Fibroblasts as Playmakers of Cancer Progression: Current Knowledge and Future Perspectives (2nd Edition)
edited by
submission deadline 20 Feb 2026 | Viewed by 268 | Submission Open
Keywords: tumor microenvironment; reactive stroma; fibroblasts; cancer progression; heterotypic interactions between cancer cells and fibroblasts; reactive stroma-targeted therapy
(This special issue belongs to the Section Molecular Cancer Biology)
AI-Driven Predictive Modeling in Radiation Therapy: Toward Precision and Personalized Clinical Applications
edited by
submission deadline 20 Feb 2026 | Viewed by 242 | Submission Open
Keywords: AI-based radiotherapy; predictive modeling in oncology; personalized radiation therapy; radiomics and dosiomics; adaptive radiotherapy; treatment outcome prediction; explainable AI in medicine; multimodal data integration; clinical decision support systems; precision cancer treatment
Molecular Tumor Boards: Promise and Limitations for Personalized Cancer Therapy: 2nd Edition
edited by
submission deadline 20 Feb 2026 | Viewed by 203 | Submission Open
Keywords: targeted therapy; drug repositioning; biomarkers; basket trials; precision oncology; personalized medicine
(This special issue belongs to the Section Molecular Cancer Biology)
Cancer and Aging: Challenges in Geriatric Cancer Survivorship
edited by and Dana E. Giza
submission deadline 20 Feb 2026 | Viewed by 74 | Submission Open
Keywords: geriatric oncology; survivorship; advance care planning; quality of life; de-escalation of treatment
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Minimal Residual Disease in Solid Tumors: Emerging Technologies and Clinical Applications
edited by , and Aristeidis Boukouris
submission deadline 25 Feb 2026 | Viewed by 191 | Submission Open
Keywords: minimal residual disease (MRD); solid tumors; circulating tumor DNA (ctDNA); liquid biopsy; tumor-informed assays; precision oncology
(This special issue belongs to the Section Cancer Biomarkers)
Radiation Therapy for Modern Management of Bone Metastases (2nd Edition)
edited by
submission deadline 25 Feb 2026 | Viewed by 178 | Submission Open
Keywords: radiotherapy; palliative care; steretactic radiotherapy; SBRT; immunotherapy; chemotherapy; oligometastases
(This special issue belongs to the Section Cancer Therapy)
Harnessing the Gut Microbiome to Improve Colorectal Cancer Outcomes
edited by Carole S. Richard
submission deadline 25 Feb 2026 | Viewed by 138 | Submission Open
Keywords: colorectal cancer (CRC); gut microbiome; screening; CRC cells; the gut microenvironment; oncological outcomes
(This special issue belongs to the Section Infectious Agents and Cancer)
Understanding HTLV-1 Induced Cancer: From Molecular Pathways to Treatment Strategies
edited by and Suchitra Mohanty
submission deadline 25 Feb 2026 | Viewed by 94 | Submission Open
Keywords: HTLV-1; adult T-cell leukemia/lymphoma (ATLL); tax protein; HBZ protein; epigenetic regulation; immune evasion; chronic inflammation; host– pathogen interactions; viral oncogenesis; translational research
(This special issue belongs to the Section Infectious Agents and Cancer)
Advances in the Treatment of Gastrointestinal (GI) Cancers
edited by
submission deadline 27 Feb 2026 | 1 articles | Viewed by 1169 | Submission Open
Keywords: gastrointestinal cancers; targeted therapy; immunotherapy; precision oncology; biomarkers; molecular mechanisms; tumor microenvironment; resistance to therapy; translational research; clinical trials
(This special issue belongs to the Section Cancer Therapy)
Clinical and Translational Updates in Renal Cell Carcinoma (2nd Edition)
edited by
submission deadline 27 Feb 2026 | Viewed by 131 | Submission Open
Keywords: renal cell carcinoma; RCC; machine cearning; clinical; translational developments
(This special issue belongs to the Section Clinical Research of Cancer)
Application of Imaging in Breast Cancer
edited by , and Chung Wai-Shan
submission deadline 28 Feb 2026 | 6 articles | Viewed by 18269 | Submission Open
Keywords: breast cancer; mammography/tomosynthesis/contrast-enhanced mammography; sonography/contrast-enhanced sonography; magnetic resonance imaging; PET/CT; quantitative imaging; elastography; optical imaging; artificial intelligence; image-guided biopsy
(This special issue belongs to the Section Methods and Technologies Development)
Challenges and Opportunities for Novel Therapeutic Strategies in Pediatric Oncology
edited by and
submission deadline 28 Feb 2026 | 7 articles | Viewed by 15875 | Submission Open
Keywords: antibody-drug conjugate; bispecific antibody; cancer predisposition; CAR T cell; immunotherapy; leukemia; monoclonal antibody; neuroblastoma; pediatric cancer; photoimmunotherapy; precision medicine; sarcoma; translational research; tyrosine kinase inhibitor
(This special issue belongs to the Section Cancer Therapy)
Advances in Bladder Preservation Approaches for Bladder Cancer (2nd Edition)
edited by and Todd A. Yezefski
submission deadline 28 Feb 2026 | 5 articles | Viewed by 12929 | Submission Open
Keywords: bladder cancer; bladder preservation; trimodality therapy; chemoradiation; immunotherapy; intravesical therapy; BCG refractory or unresponsive
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
State of the Art and Novelties in Multidisciplinary Approach to Soft Tissue and Bone Sarcomas
edited by Ron Batash, Alberto Crimì, Moshe Schaffer and
submission deadline 28 Feb 2026 | 6 articles | Viewed by 11702 | Submission Open
Keywords: soft tissue sarcoma; bone sarcoma; treatment; diagnosis; radiation therapy; chemotherapy
(This special issue belongs to the Section Cancer Therapy)
Advances in Oncological Imaging (2nd Edition) submission deadline 28 Feb 2026 | 5 articles | Viewed by 9049 | Submission Open
Keywords: oncological imaging; radiomics; deep learning; machine learning; image reconstruction; artificial intelligence; outcome prediction; oncological treatment planning; advanced imaging; personalized medicine
(This special issue belongs to the Section Methods and Technologies Development)
Improving Surgical Care for Patients with Hepatobiliary and Pancreatic Cancers
edited by Christopher B. Nahm and Kai M. Brown
submission deadline 28 Feb 2026 | 2 articles | Viewed by 7731 | Submission Open
Keywords: hepatobiliary; pancreatic; surgery; biomarkers; prognosis; treatment strategy
(This special issue belongs to the Section Cancer Therapy)
Navigating the Landscape of Female Cancers: Recent Discoveries and Treatment Trends
edited by and Giacomo Barchiesi
submission deadline 28 Feb 2026 | 3 articles | Viewed by 7662 | Submission Open
Keywords: female malignancies; breast cancer; gynecological cancer; ovarian cancer; endometrial cancer; cervical cancer
(This special issue belongs to the Section Cancer Therapy)
New Insights into General, Functional and Oncologic Urology
edited by Kajetan Juszczak and
submission deadline 28 Feb 2026 | 4 articles | Viewed by 7141 | Submission Open
Keywords: basic science; experimental models; urological cancer; management innovations; multidisciplinary approaches; treatment outcomes
(This special issue belongs to the Section Clinical Research of Cancer)
Regulators of Breast Cancer Metastasis submission deadline 28 Feb 2026 | 2 articles | Viewed by 6717 | Submission Open
Keywords: tumor progression regulators; metastasis; tumor microenvironment; biomarkers for recurrence; transcriptional regulation; chromatin structure; epigenetics; cancer metabolism; cancer immunity; microbiome
(This special issue belongs to the Section Cancer Metastasis)
Cervical Cancer: Clinical Feature, Trial and Management
edited by , and Carlo Saccardi
submission deadline 28 Feb 2026 | 2 articles | Viewed by 5677 | Submission Open
Keywords: cervical cancer; diagnosis; minimally invasive surgery; laparoscopy; locally advanced disease; management; treatment; adjuvant chemotherapy; immunotherapy
(This special issue belongs to the Section Cancer Therapy)
Diagnosis, Staging, and Management for Gynecologic Oncology
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 5427 | Submission Open
Keywords: gynecologic oncology; cancer biology; HPV infection; molecular risk factors; translational medicine; cancer staging systems; radiation therapy; brachytherapy; radioresistance
(This special issue belongs to the Section Cancer Therapy)
Personalized Radiotherapy in Cancer Care (2nd Edition)
edited by and
submission deadline 28 Feb 2026 | 3 articles | Viewed by 5220 | Submission Open
Keywords: predictive biomarkers; treatment-related toxicity; radiation treatments; radiation dose and volume; personalized radiation therapy
(This special issue belongs to the Section Methods and Technologies Development)
3D Cultures and Organoids in Cancer Research submission deadline 28 Feb 2026 | 1 articles | Viewed by 5064 | Submission Open
Keywords: 3D cell cultures; organotypic 3D cultures; 3D spheroids models; induced pluripotent stem (iPS); organoids; tumoroids
(This special issue belongs to the Section Molecular Cancer Biology)
Exploring Non-Coding RNA Signatures in Cancer: Definitions and Implications for Diagnosis and Therapy
edited by and Udhayakumar Gopal
submission deadline 28 Feb 2026 | 5 articles | Viewed by 4767 | Submission Open
Keywords: non-coding RNA; biomarkers; gene regulation; microRNA; long non-coding RNA; circular RNA; therapeutic targets
(This special issue belongs to the Section Cancer Therapy)
Perioperative Care in Gynecologic Oncology: 2nd Edition
edited by Nikolaos Thomakos and
submission deadline 28 Feb 2026 | 2 articles | Viewed by 3843 | Submission Open
Keywords: enhanced recovery; ERAS; immunonutrition; prehabilitation; gynecologic oncology; minimally invasive surgery
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
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