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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Study on Clinical Treatment of Brain Tumors
edited by Shinya Watanabe
submission deadline 9 Sep 2026 | 3 articles | Viewed by 9666 | Submission Open
Keywords: brain tumors; clinical treatment; anti-tumor drugs; clinical trials
(This special issue belongs to the Section Cancer Therapy)
Quality of Life and Side Effects Management in Cancer Treatment (3rd Edition)
edited by
submission deadline 10 Sep 2026 | 7 articles | Viewed by 16988 | Submission Open
Keywords: cancer treatment adverse events; quality of life in cancer patients; chemotherapy adverse events; target therapy adverse events; immunotherapy adverse events; hormonotherapy adverse events; chemotherapy-induced nausea and vomiting; cancer pain
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Exercise and Cancer Treatment: The Clinical Application of Exercise Oncology
edited by and Geovana Leite
submission deadline 10 Sep 2026 | 4 articles | Viewed by 5006 | Submission Open
Keywords: exercise oncology; cancer therapy; immunotherapy; patient outcomes
(This special issue belongs to the Section Clinical Research in Cancer)
Skin Cancer Prevention: Strategies, Challenges and Future Directions
edited by Véronique del Marmol, Mariano Suppa, Ana-Maria Forsea and Alexander Stratigos
submission deadline 15 Sep 2026 | 8 articles | Viewed by 16696 | Submission Open
Keywords: skin cancer prevention; photoprotection; early detection; screening; epidemiology; public health; behavioral interventions; sun exposure; artificial intelligence; risk factors
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Advances in Interventional Oncologic Therapies
edited by Edward W. Lee and
submission deadline 15 Sep 2026 | 4 articles | Viewed by 15771 | Submission Open
(This special issue belongs to the Section Cancer Therapy)
Advances in Artificial Intelligence Methodologies and Applications in Cancer
edited by Jennifer G. Le-Rademacher and
submission deadline 15 Sep 2026 | 4 articles | Viewed by 8411 | Submission Open
Keywords: artificial intelligence (AI); AI tools; cancer research; diagnostic tools; medical imaging; biomarkers; ethical considerations; patient care
(This special issue belongs to the Section Methods and Technologies Development)
First-Line Therapy in Thoracic Oncology
edited by Antonio D'Andrilli and
submission deadline 15 Sep 2026 | 4 articles | Viewed by 7369 | Submission Open
Keywords: thoracic oncology; lung cancer; thymoma; mediastinal tumors
(This special issue belongs to the Section Cancer Therapy)
Robot-Assisted Surgery for Urologic Cancer
edited by Gabriele Sorce, Francesco Pellegrino and Ettore Di Trapani
submission deadline 15 Sep 2026 | 3 articles | Viewed by 6978 | Submission Open
Keywords: robot-assisted surgery; urologic oncology; minimally invasive surgery; prostate cancer surgery; kidney cancer surgery; bladder cancer surgery; robotic platforms; robotic surgery training
(This special issue belongs to the Section Cancer Therapy)
Radiotherapy for Sarcoma
edited by Safia K. Ahmed and Miranda Lam
submission deadline 15 Sep 2026 | 3 articles | Viewed by 5326 | Submission Open
Keywords: soft tissue sarcoma; bone sarcoma; advanced sarcoma; radiation therapy; particle therapy; multidisciplinary sarcoma care
(This special issue belongs to the Section Cancer Therapy)
Endometrial Cancer Therapy: Foundations and Future Directions submission deadline 15 Sep 2026 | 4 articles | Viewed by 3755 | Submission Open
Keywords: pathology; surgery; radiotherapy; chemotherapy; new agents; immunotherapy; artificial intelligence
(This special issue belongs to the Section Cancer Therapy)
Treatment of Acute Kidney Injury in Cancer Patients: From Theory to Practice
edited by and Shveta S. Motwani
submission deadline 15 Sep 2026 | 1 articles | Viewed by 2811 | Submission Open
Keywords: immune check point inhibitor related nephritis; MGRS; CART cell therapy; stem cell transplant; TMA; BK nephropathy; cisplatin nephropathy
(This special issue belongs to the Section Cancer Therapy)
Breast Cancer: Immune Response, Immune Microenvironment, and Immunotherapy submission deadline 15 Sep 2026 | 2 articles | Viewed by 2316 | Submission Open
Keywords: breast cancer; immune response; tumor immune microenvironment; immunotherapy resistance; intrinsic and extrinsic mechanisms; immune checkpoint inhibitors; T-cell dysfunction; cytokines; cancer vaccines; tumor immunosuppression
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Childhood Acute Lymphoblastic Leukemia
edited by Noriko Satake
submission deadline 15 Sep 2026 | 2 articles | Viewed by 1659 | Submission Open
Keywords: childhood acute lymphoblastic leukemia; diagnosis; novel agents; targeted therapy; personalized medicine
(This special issue belongs to the Section Pediatric Oncology)
The Clinical, Technological, and Scientific Progress of Boron Neutron Capture Therapy
edited by
submission deadline 15 Sep 2026 | Viewed by 1454 | Submission Open
Keywords: boron neutron capture therapy (BNCT); neutron capture therapy (NCT); accelerator-based neutron source; neutron dosimetry; boron drug development; alternative capture agents; radiobiological effects; radiation oncology; interdisciplinary research; clinical translation
(This special issue belongs to the Section Cancer Therapy)
Evidence-Based Care for Managing Oncologic Emergencies in Patients with Cancer submission deadline 15 Sep 2026 | 1 articles | Viewed by 1179 | Submission Open
Keywords: oncologic emergencies; cancer; urgent; infections; adverse events; thrombosis; febrile neutropenia; pain; spinal cord compression; goals of care
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
New Models of Cancer Care to Improve Patient Experiences and Clinical Outcomes
edited by
submission deadline 15 Sep 2026 | 1 articles | Viewed by 1100 | Submission Open
Keywords: patient-centered care; community-based interventions; innovative care models; digital health solutions; patient engagement; clinical outcomes; value-based cancer care
Advances in Endoscopy for Early Detection and Precision Diagnosis of Gastrointestinal Cancers
edited by Ishaan Vohra
submission deadline 15 Sep 2026 | 1 articles | Viewed by 981 | Submission Open
Keywords: endoscopy; gastrointestinal cancer; early detection; artificial intelligence; advanced imaging; molecular diagnostics; precision medicine; biomarkers; screening; surveillance
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Advances in Breast Conservation Therapy: A Global Perspective
edited by Tristen S. Park
submission deadline 15 Sep 2026 | Viewed by 233 | Submission Open
Keywords: breast conservation therapy; survival; breast cancer
(This special issue belongs to the Section Cancer Therapy)
Aptamers Against Cancer submission deadline 15 Sep 2026 | Viewed by 221 | Submission Open
Keywords: aptamers; cancer theranostics; targeted therapy; biosensors; molecular imaging
(This special issue belongs to the Section Methods and Technologies Development)
Hepatocellular Carcinoma: Risk Factors, Diagnosis and Treatments submission deadline 15 Sep 2026 | Viewed by 212 | Submission Open
Keywords: chronic hepatitis; cirrhosis; viral hepatitis; HCC; MASLD; imaging; TACE; radio-ablation; chemotherapy
Onco-Nephrology: From Molecular to Clinical Studies submission deadline 16 Sep 2026 | 1 articles | Viewed by 2264 | Submission Open
Keywords: acute kidney injury in oncology; chronic kidney disease and cancer; paraneoplastic glomerulonephritis; immunotherapy-related nephrotoxicity; tumor lysis syndrome; nephrotoxicity of chemotherapeutic agents; DNA damage; epigenetic modifications; molecular pathways in cancer-associated kidney injury; biomarkers for early detection of kidney injury
(This special issue belongs to the Section Clinical Research in Cancer)
T Cells in Hematologic Malignancies: Biology, Microenvironment, and Therapeutic Advances submission deadline 16 Sep 2026 | 1 articles | Viewed by 1658 | Submission Open
Keywords: T cells; hematologic malignancies; CAR-T therapy; bispecific T cell engagers; tumor immune microenvironment; T cell dysfunction and exhaustion; leukemia, lymphoma, and myeloma; acute myeloid leukemia and MDS; immunotherapy resistance and relapse; next-generation cellular therapies
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Advances and Innovations in Cancer Drug Therapeutics
edited by
submission deadline 17 Sep 2026 | Viewed by 219 | Submission Open
Keywords: cancer; drug discovery; targeted drugs; computer-aided drug discovery; formulation advances; immunotherapy; transcriptomics; proteomics; metabolomics
(This special issue belongs to the Section Cancer Drug Development)
Artificial Intelligence in Ocular Oncology
edited by
submission deadline 18 Sep 2026 | 3 articles | Viewed by 2576 | Submission Open
Keywords: ocular tumor; eye cancer; artificial intelligence; ophthalmology
(This special issue belongs to the Section Methods and Technologies Development)
Management of Pancreatic Cancer: 2nd Edition
edited by
submission deadline 18 Sep 2026 | Viewed by 314 | Submission Open
Keywords: pancreatic cancer; adenocarcinoma; neuroendocrine carcinomas; molecular and pathological aspects; diagnosis; medical treatment; palliative therapy
Advances in Salivary Gland Carcinoma: 2nd Edition
edited by
submission deadline 20 Sep 2026 | 3 articles | Viewed by 11813 | Submission Open
Keywords: salivary gland tumors; head and neck cancer; facial nerve preservation; facial nerve reconstruction; facial nerve sacrifice; parotid cancer; parotidectomy; prognostic factors
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Clinical Outcomes in Upper GI Cancers
edited by
submission deadline 20 Sep 2026 | 5 articles | Viewed by 2724 | Submission Open
Keywords: esophageal cancer; gastric cancer; esophagogastric junction cancer; surgery; endoscopy; chemotherapy; immuno-therapy; molecural target therapy; biomarker
(This special issue belongs to the Section Clinical Research in Cancer)
Molecular Pathology Insights in Thyroid Cancer
edited by Salma Khan
submission deadline 20 Sep 2026 | Viewed by 499 | Submission Open
Keywords: non-coding RNAs; epigenetics; biomarkers; BRAF mutations; RAS mutations; targeted therapy; precision medicine; genomic profiling; tumor heterogeneity; therapeutic resistance
(This special issue belongs to the Section Cancer Pathophysiology)
Development of Hepatitis C Virus-Related Cancers
edited by
submission deadline 20 Sep 2026 | 1 articles | Viewed by 484 | Submission Open
Keywords: hepatitis C virus (HCV); hepatocellular carcinoma (HCC); extrahepatic malignancies; lymphoproliferative disorders; viral oncogenesis; chronic inflammation and cancer; direct-acting antivirals (DAAs); cancer surveillance in HCV patients
(This special issue belongs to the Section Clinical Research in Cancer)
Advances in Targeting Drug-Resistant Tumors: Approaches Mitigating Inflammation and Oxidative Stress Pathways submission deadline 20 Sep 2026 | Viewed by 201 | Submission Open
Keywords: inflammation; oxidative stress; reactive oxygen species; Nrf2; NFkB; HPGD; drug resistance
(This special issue belongs to the Section Cancer Drug Development)
Clinical Advances in Colorectal Cancers submission deadline 20 Sep 2026 | Viewed by 192 | Submission Open
Keywords: colon cancer; rectal cancer; cancer research; ctDNA; immunotherapy; targeted therapy; colorectal surgery
(This special issue belongs to the Section Clinical Research in Cancer)
Advances in Bone Metastasis Research: From Mechanisms to Therapy
edited by Ye Lin
submission deadline 25 Sep 2026 | 1 articles | Viewed by 2007 | Submission Open
Keywords: bone metastasis; tumour microenvironment; biomarker; targeted therapy; detection; palliative care
(This special issue belongs to the Section Cancer Metastasis)
Study on Surgical Treatment of Ovarian Cancer
edited by Theo Panoskaltsis
submission deadline 25 Sep 2026 | 2 articles | Viewed by 1318 | Submission Open
Keywords: ovarian cancer; surgical treatment; ovarian cancer prevention
(This special issue belongs to the Section Cancer Therapy)
Combination Immunotherapy for Cancer Treatment—2nd Edition submission deadline 25 Sep 2026 | 1 articles | Viewed by 1182 | Submission Open
Keywords: immunotherapy; immune checkpoint inhibitor; cancer vaccine; novel cancer therapy; treatment
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Imaging-Based Cancer Radiotherapy
edited by and Alberto Traverso
submission deadline 25 Sep 2026 | 1 articles | Viewed by 637 | Submission Open
Keywords: radiotherapy; imaging biomarkers; artificial intelligence; radiomics; toxicity prediction; adaptive radiotherapy; automated treatment planning; image-guided radiotherapy; multimodal learning; precision oncology
(This special issue belongs to the Section Methods and Technologies Development)
Targeting the Vulnerabilities of Oncogene Activation (Second Edition)
edited by
submission deadline 25 Sep 2026 | Viewed by 516 | Submission Open
Keywords: tumorigenesis; tumor-suppressor genes; oncogene; target
(This special issue belongs to the Section Methods and Technologies Development)
Role of Iron Metabolism in Tumor Progression
edited by
submission deadline 25 Sep 2026 | Viewed by 331 | Submission Open
Keywords: iron metabolism; ferroptosis; tumor microenvironment; oxidative stress; iron chelation therapy; ferritin; transferrin receptor; cancer metabolism; redox homeostasis; therapeutic targeting
(This special issue belongs to the Section Molecular Cancer Biology)
Acute Myeloid Leukemia: Updates on Diagnosis and Novel Management Strategies
edited by Ana Vidović
submission deadline 25 Sep 2026 | Viewed by 328 | Submission Open
Keywords: acute myeloblastic leukemia; diagnosis; prognosis; intensive chemotherapy; target therapy; allogeneic stem cell transplantation
(This special issue belongs to the Section Clinical Research in Cancer)
Clinical Pathology in Cancer: From Diagnosis to Precision Medicine
edited by
submission deadline 28 Sep 2026 | Viewed by 481 | Submission Open
Keywords: cancer biomarkers; precision medicine; histopathology; clinical pathology; diagnosis; prognostic/predictive biomarker
(This special issue belongs to the Section Cancer Pathophysiology)
Advances and Challenges in the Diagnosis and Treatment of Urological Malignancies (2nd Edition) submission deadline 30 Sep 2026 | 9 articles | Viewed by 21027 | Submission Open
Keywords: prostate cancer; bladder cancer; upper urinary tract tumors; kidney cancer; testicular tumors; molecular markers; lymph node metastasis; diagnosis; radical treatment; systemic treatment
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Advances in Soft Tissue and Bone Sarcoma (2nd Edition) submission deadline 30 Sep 2026 | 13 articles | Viewed by 15882 | Submission Open
Keywords: bone sarcoma; soft tissue sarcoma; prognosis; diagnosis; detection; molecular biomarkers; histopathology; treatment
(This special issue belongs to the Section Cancer Therapy)
Immunotherapy for Skin Cancers
edited by and Lara Valeska Maul-Duwendag
submission deadline 30 Sep 2026 | 4 articles | Viewed by 12117 | Submission Open
Keywords: melanoma; non-melanoma skin cancer; merkel cell carcinoma; kaposi sarcoma; cutaneous angi-osarcoma; immune checkpoint; immunotherapy
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Decision-Making Biomarkers in the Treatment of Hepatocellular Carcinoma
edited by and
submission deadline 30 Sep 2026 | 5 articles | Viewed by 11049 | Submission Open
Keywords: hepatocellular carcinoma; borderline resectable; conversion therapy; neoadjuvant therapy; immunotherapy; immune-related adverse event; molecular-targeted agent
(This special issue belongs to the Section Cancer Biomarkers)
Health Economic and Policy Issues Regarding Cancer
edited by
submission deadline 30 Sep 2026 | 4 articles | Viewed by 8586 | Submission Open
Keywords: cancer economics; health policy; cost-effectiveness; financial toxicity; healthcare disparities; value-based oncology
Neurosurgery Research on Brain Tumors: A Focus on Gliomas and Other Intra-Axial Brain Tumors
edited by , Carlo Giussani, Cesare Zoia and Daniele Bongetta
submission deadline 30 Sep 2026 | 2 articles | Viewed by 7879 | Submission Open
Keywords: neurosurgery; glioma; neuropsychology; neurophysiological monitoring; intraoperative imaging (including iMRI and iOUS); neuroanatomy; outcome; prognosis and quality of life; MRI (including fMRI, MR spectroscopy, perfusion and DTI tractography); radiogenomics; multimodal treatments; druggable targets; artificial intelligence and deep learning
(This special issue belongs to the Section Clinical Research in Cancer)
Cellular and Molecular Mechanisms of Malignant Nervous System Cancers
edited by
submission deadline 30 Sep 2026 | 7 articles | Viewed by 7346 | Submission Open
Keywords: medulloblastoma; pediatric glioma; neuroblastoma; diagnosis and prognostic markers; IDH, TERT, and EGFR mutations; DNA methylation; treatment approaches and strategies (chemotherapy, radiation therapy, immunotherapy, and targeted therapy); resistance mechanisms; tumor microenvironment; molecular characteristics of tumor heterogeneity
(This special issue belongs to the Section Molecular Cancer Biology)
The EGFR-Tyrosine Kinase Inhibitors (EGFR-TKIs) and Immune Checkpoint Inhibitors (ICIs) for Non-Small Cell Lung Cancer submission deadline 30 Sep 2026 | 2 articles | Viewed by 6544 | Submission Open
Keywords: non-small cell lung cancer; target therapy; EGFR-tyrosine kinase inhibitors; immunotherapy; immune checkpoint inhibitors; molecular analysis; surgery; precision medicine
(This special issue belongs to the Section Cancer Therapy)
Fertility Preservation and Hormonal Health in Oncology submission deadline 30 Sep 2026 | 4 articles | Viewed by 6318 | Submission Open
Keywords: oncofertility; fertility preservation; hormonal health; cancer survivorship; reproductive oncology
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Novel Perspectives in Hepato-Biliary and Pancreatic Cancer
edited by Tudor Mocan and Emil-Ioan Moiș
submission deadline 30 Sep 2026 | 4 articles | Viewed by 6232 | Submission Open
Keywords: HCC; cholangiocarcinoma; surgery; biliary drainage; pancreatic cancer; combination therapies
(This special issue belongs to the Section Cancer Therapy)
Biomarkers for Therapy Response in Gastrointestinal Malignancies: Predicting Outcomes and Personalizing Care submission deadline 30 Sep 2026 | 5 articles | Viewed by 6231 | Submission Open
Keywords: immunotherapy; biomarkers; resistance mechanisms; predictive markers; clinical trials; translational research
(This special issue belongs to the Section Cancer Biomarkers)
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