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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Pheochromocytoma and Paraganglioma: Molecular Insights and Clinical Frontiers

edited by

Ivana Jochmanová

submission deadline 31 Jul 2026 | Viewed by 83 | Submission Open

Keywords: pheochromocytoma and paraganglioma; hereditary cancer syndromes; genetic mutations; genotype– phenotype correlations; functional imaging; molecular diagnostics; biomarkers; precision oncology; targeted therapy

(This special issue belongs to the Section Cancer Therapy)

Perioperative Care and Pain Management in Cancer Patients: From Basic Science to Clinical Practice—2nd Edition

edited by

Dario Bugada

submission deadline 31 Jul 2026 | Viewed by 82 | Submission Open

Keywords: perioperative care; cancer anesthesia; analgesia; pain management

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Artificial Intelligence in Radiation Therapy for Head and Neck Cancers: Prediction, Personalization, and Precision

edited by Meysam Tavakoli

submission deadline 31 Jul 2026 | Viewed by 81 | Submission Open

Keywords: head and neck cancer; radiation therapy; artificial intelligence ; machine learning ; deep learning ; toxicity prediction ; radiomics ; dosiomics ; outcome modeling ; personalized radiotherapy

(This special issue belongs to the Section Methods and Technologies Development)

Microsatellite Instability in Colorectal Cancer

edited by

Joan Maurel

and Vicente Alonso-Orduña

submission deadline 31 Jul 2026 | Viewed by 79 | Submission Open

Keywords: microsatellite instability; colorectal cancer; immune checkpoint inhibitors; immune signatures

(This special issue belongs to the Section Tumor Microenvironment)

Tumorigenesis and Tumor Microenvironment—Insights and Interventions (TTMII)

edited by

Renu Wadhwa

Sunil C. Kaul

and

Ajaikumar B. Kunnumakkara

submission deadline 31 Jul 2026 | Viewed by 74 | Submission Open

Keywords: tumorigenesis; tumor microenvironment; intervention; stress biology; aging; mortalin; CARF; ashwagandha; propolis; curcumin; natural compounds

(This special issue belongs to the Section Tumor Microenvironment)

Mitochondrial Metabolism and Cancer

edited by

Marcos Roberto de Oliveira

submission deadline 31 Jul 2026 | Viewed by 73 | Submission Open

Keywords: mitochondria; mitochondrial metabolism; cancer; bioenergetics; metabolomics; proteomics; mitochondrial dynamics; therapeutic targets; drug resistance

(This special issue belongs to the Section Molecular Cancer Biology)

Allogeneic Hematopoietic Stem Cell Transplantation (Allo-HSCT) in Patients with Cancers

edited by Caterina Alati and Martina Pitea

submission deadline 31 Jul 2026 | Viewed by 68 | Submission Open

Keywords: hematopoietic stem cell; hematologic malignancies; transplantation; immunotherapy

(This special issue belongs to the Section Transplant Oncology)

Advances in Dermato-Oncology

edited by Carmen Cantisani

submission deadline 31 Jul 2026 | Viewed by 66 | Submission Open

Keywords: melanoma; line-field confocal optical coherence tomography (LC-OCT); confocal microscopy; dermoscopy; non-melanoma skin cancers; treatment

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Cancer After Kidney Transplant

edited by Sławomir Lizakowski

submission deadline 31 Jul 2026 | Viewed by 46 | Submission Open

Keywords: immunosuppression; virus-associated cancer; skin cancer; graft survival; kidney transplantation; post-transplantation lymphoproliferative disorder

(This special issue belongs to the Section Transplant Oncology)

Oncological Healthcare: Emergency and Supportive/Palliative Approaches

edited by Ahmed Elsayem and Pavitra Parimala Krishnamani

submission deadline 31 Jul 2026 | Viewed by 44 | Submission Open

Keywords: supportive oncology; palliative care; symptom distress; emergency medicine; critical care; goals of care

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Multiple Myeloma and Immunology: From Pathophysiology to Therapy

edited by Marco Rossi

submission deadline 31 Jul 2026 | Viewed by 23 | Submission Open

Keywords: multiple myeloma microenvironment; immunotherapy; T cell redirecting agents; CAR-T in multiple myeloma

(This special issue belongs to the Section Tumor Microenvironment)

Multi-Omics Approaches to Tumor Antigen Discovery and Immunotherapy Target Identification

edited by

Esen Yonca Bassoy

and Parvin Zamani

submission deadline 31 Jul 2026 | Submission Open

Keywords: tumor antigen discovery; multi-omics integration; cancer immunotherapy; spatial transcriptomics; tumor microenvironment; translational immunology

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Novel Therapies in Metastatic Castration-Resistant Prostate Cancer

edited by Kathryn E. Meier

submission deadline 1 Aug 2026 | 1 articles | Viewed by 3490 | Submission Open

Keywords: signal transduction inhibitors; targeted therapies; immunotherapy; radiopharmaceuticals; PARP inhibitors; biomarker-based approaches

(This special issue belongs to the Section Cancer Therapy)

Clinical Trials and Evolving Treatment Paradigms in Urologic Cancers

edited by

Zin War Myint

submission deadline 1 Aug 2026 | Viewed by 73 | Submission Open

Keywords: urologic cancers; clinical trials; prostate cancer; bladder cancer; kidney cancer; testicular cancer; systemic therapy; meta-analysis; biomarkers; oncology innovation

(This special issue belongs to the Section Clinical Research of Cancer)

The Clinical Trials and Management of Acute Myeloid Leukemia: 2nd Edition

edited by

Margaret T. Kasner

submission deadline 7 Aug 2026 | Viewed by 48 | Submission Open

Keywords: acute myeloid leukemia; clinical trials; translational research; targeted therapies; novel agents

(This special issue belongs to the Section Clinical Research of Cancer)

Innovations in Active Surveillance Management of Early Prostate Cancer

edited by

Vincent J. Gnanapragasam

submission deadline 8 Aug 2026 | 1 articles | Viewed by 771 | Submission Open

Keywords: prostate cancer; risk stratification; active surveillance; predictive markers; personalized management; imaging; biomarkers; clinical pathways; patient outcomes; standardizing care; attrition; cohort studies

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Targeted Therapies in Sarcomas: Overcoming Resistance and Improving Outcomes

edited by

Varun Monga

and Mohammed M. Milhem

submission deadline 8 Aug 2026 | Viewed by 56 | Submission Open

Keywords: sarcoma; targeted therapy; resistance mechanisms; combination therapy; biomarkers; precision oncology; translational research; clinical trials

(This special issue belongs to the Section Tumor Microenvironment)

Clinical Surgery for Hepato-Pancreato-Biliary (HPB) Cancer

edited by

Gennaro Nappo

and

Michele Pagnanelli

submission deadline 10 Aug 2026 | 10 articles | Viewed by 14058 | Submission Open

Keywords: pancreatic malignancies; HPB malignancies; pancreatic ductal adenocarcinoma; liver cholangiocarcinoma; HPB surgery; liver resection; pancreatic resection

(This special issue belongs to the Section Cancer Therapy)

Near-Infrared Photoimmunotherapy for Cancer Treatment: 2nd Edition

edited by

Hisataka Kobayashi

submission deadline 10 Aug 2026 | Viewed by 297 | Submission Open

Keywords: NIR-PIT; phototherapy; monoclonal antibody; imaging biomarker; immunotherapy

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Bridging Translational and Clinical Oncology in Gastrointestinal Cancers: Molecular Mechanisms to Therapeutic Advances

edited by

Stavros Papadakos

Ioannis Katsaros

and

Stamatios E. Theocharis

submission deadline 10 Aug 2026 | Viewed by 84 | Submission Open

Keywords: gastrointestinal cancers; translational oncology; molecular mechanisms; biomarkers; immunotherapy; radiomics; precision medicine; therapeutic advances

(This special issue belongs to the Section Methods and Technologies Development)

Research on Clinical Treatment of Mesothelioma: 2nd Edition

edited by

Giulia M. Stella

submission deadline 10 Aug 2026 | Viewed by 36 | Submission Open

Keywords: pleural mesothelioma; targeted therapy; local treatments; radiomics; genetic traits; occupational health; asbestos exposure

(This special issue belongs to the Section Clinical Research of Cancer)

The Tumorigenesis Mechanism of Breast Cancer

edited by Swayam Prabha

submission deadline 10 Aug 2026 | Viewed by 30 | Submission Open

Keywords: breast cancer; tumor microenvironment; myeloid-derived suppressor cells; immune evasion; premetastatic niche; epithelial– mesenchymal transition; PI3K/AKT/mTOR; MAPK/ERK; Wnt/β -catenin; BRCA1/2; TP53; estrogen signaling; targeted therapy; nanomedicine; biologics; precision oncology; translational research

(This special issue belongs to the Section Molecular Cancer Biology)

Recent Updates and Future Perspectives of Anti-Cancer Agents

edited by

Santosh Kumar Singh

submission deadline 15 Aug 2026 | 1 articles | Viewed by 1730 | Submission Open

Keywords: cancer; anti-cancer agents; targeted therapy; drug resistance; therapeutic agents; natural compounds; combination therapy; nanotherapy; translational therapy; immunotherapy

(This special issue belongs to the Section Cancer Drug Development)

Immunotherapy for Hematologic Malignancies

edited by Rajesh Ramakrishnan Nair

submission deadline 15 Aug 2026 | Viewed by 114 | Submission Open

Keywords: immune evasion; immunotherapy; CAR-T cell therapy; BiTEs; immunomodulators; checkpoint; inhibitors; bone marrow microenvironment; refractory/relapsed; drug resistance; gene editing

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Rare Genitourinary Cancers

edited by

Luis G Medina

and

Philippe E. Spiess

submission deadline 15 Aug 2026 | Viewed by 111 | Submission Open

Keywords: rare genitourinary tumors; penile cancer; testicular cancer; urethral cancer; adrenal cancer; variant histology; upper tract urothelial carcinoma; extramammary Paget’ s disease; urologic oncology; rare cancers

(This special issue belongs to the Section Clinical Research of Cancer)

Clinical Applications of Advanced MRI Technologies for Cancers

edited by

Nicolò Cardobi

submission deadline 15 Aug 2026 | Viewed by 72 | Submission Open

Keywords: advanced MRI techniques; multiparametric imaging; quantitative biomarkers; artificial intelligence; treatment response assessment; precision oncology; radiomics; cancer diagnosis; functional imaging; molecular imaging

(This special issue belongs to the Section Methods and Technologies Development)

Rare Cancers, Diagnostic Challenges and Personalized Therapeutic Approaches in the 21st Century (2nd Edition)

edited by

Jason Roszik

submission deadline 20 Aug 2026 | 2 articles | Viewed by 2040 | Submission Open

Keywords: rare cancer; biology; diagnosis; classification; personalized therapeutics; markers

(This special issue belongs to the Section Cancer Therapy)

Advances in Clinical, Diagnostic and Neurosurgical Management in Pediatric Neuro-Oncology

edited by

John Ross Crawford

and Michael Levy

submission deadline 20 Aug 2026 | Viewed by 162 | Submission Open

Keywords: neuro-oncology; brain tumors; neuroradiology; proton therapy; pediatric; neurosurgery; treatment; chemotherapy; targeted agents; molecular subtypes; immunotherapy; late effects; radiation therapy

(This special issue belongs to the Section Pediatric Oncology)

Socio-Demographic Factors and Cancer Research: 2nd Edition

edited by

Mitchell S. Fourman

and Amanda N. Goldin

submission deadline 20 Aug 2026 | Viewed by 126 | Submission Open

Keywords: socio-economic disparity; cancer delivery; cancer survival; metastatic cancer; culture-specific cancer outcomes; AI; machine learning

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Advances in Surgery for Endocrine Cancers

edited by Michael Bouvet and Eren Berber

submission deadline 20 Aug 2026 | Viewed by 59 | Submission Open

Keywords: thyroid cancer; thyroid surgery; hyperparathyroidism; adrenal tumors; adrenal surgery; pancreatic neuroendocrine tumors; fluorescence guided surgery; intraoperative imaging; surgical navigation; technological innovation

(This special issue belongs to the Section Methods and Technologies Development)

Pain and Palliative Care in Patients with Cancers

edited by

Arpad Szallasi

and

Anna Horváth

submission deadline 20 Aug 2026 | Viewed by 40 | Submission Open

Keywords: cancer pain; palliative care; opioid tolerance

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Diagnostic Biomarkers in Cancers Study

edited by Zejuan Li and

Xin Yi

submission deadline 21 Aug 2026 | 3 articles | Viewed by 5352 | Submission Open

Keywords: cancer; diagnostics; biomarker

(This special issue belongs to the Section Cancer Biomarkers)

Contemporary Diagnosis and Management of Prostate Cancer (2nd Edition)

edited by Thomas Jang

submission deadline 22 Aug 2026 | 1 articles | Viewed by 796 | Submission Open

Keywords: prostate cancer; diagnosis; management; radical prostatectomy; biomarkers

(This special issue belongs to the Section Cancer Therapy)

Study on Clinical Studies of Colorectal Cancer Surgery

edited by

Konstantinos Perivoliotis

and Ioannis Baloyiannis

submission deadline 25 Aug 2026 | Viewed by 20 | Submission Open

Keywords: colon; rectal; cancer; clinical; trials; evidence; open; laparoscopic; robotic; surgery

(This special issue belongs to the Section Clinical Research of Cancer)

Modern Approach to Oral Cancer

edited by

Maria Maddalena Marrapodi

and

Giuseppe Minervini

submission deadline 30 Aug 2026 | 11 articles | Viewed by 45485 | Submission Open

Keywords: oral cancer; neoplasm; oral surgery oncogenesis; dentistry oral health

(This special issue belongs to the Section Cancer Therapy)

Pathology of Acute Myeloid Leukemia (AML)

edited by Olga K. Weinberg

submission deadline 30 Aug 2026 | Viewed by 1249 | Submission Open

(This special issue belongs to the Section Cancer Pathophysiology)

Long-Term Health Outcomes and Quality of Life in Survivors of Childhood Cancer

edited by

Esteban Orenes-Piñero

submission deadline 30 Aug 2026 | 1 articles | Viewed by 533 | Submission Open

Keywords: acute lymphoblastic leukemia; brain tumors; childhood cancer survivors; pollutants; environment; quality of life; nutrition; chemotherapy; air and water purification

(This special issue belongs to the Section Pediatric Oncology)

Pathology of Gynecological Cancers (2nd Edition)

edited by

Mohamed Desouki

submission deadline 30 Aug 2026 | Viewed by 250 | Submission Open

Keywords: endometrial cancer; ovarian cancer; vulvar cancer; cervical cancer; vaginal cancer

(This special issue belongs to the Section Cancer Pathophysiology)

Proteometabolomics in Cancer

edited by

Samir M. Hanash

and

Johannes Fahrmann

submission deadline 30 Aug 2026 | Viewed by 130 | Submission Open

Keywords: proteomics; metabolomics; cancer biology; tumor microenvironment; biomarkers; therapeutics

(This special issue belongs to the Section Molecular Cancer Biology)

Robotic and Laparoscopic Surgery in Colorectal Cancer: Current Trends and Future Perspectives

edited by

Felix Aigner

, Quentin Denost and Barbara Noiret

submission deadline 30 Aug 2026 | Viewed by 98 | Submission Open

Keywords: robotic surgery; laparoscopic surgery; colorectal cancer; minimally invasive surgery; comparative outcomes (perioperative; oncologic; functional); conversion rates; open surgery; learning curve and surgical training; cost‐effectiveness and health economics; technological innovations (e.g.; AI; imaging; instrumentation); quality of life and long‐term patient‐reported outcomes

(This special issue belongs to the Section Cancer Therapy)

Tumor Suppressor and Targeted Therapy in Hepatocellular Carcinoma: From Diagnosis to Treatment (2nd Edition)

edited by

Ching-Sheng Hsu

Po-Heng Chuang

and I-Cheng Lee

submission deadline 30 Aug 2026 | Viewed by 81 | Submission Open

Keywords: tumor suppressor; targeted therapy; hepatocellular carcinoma

(This special issue belongs to the Section Tumor Microenvironment)

Neoantigen Vaccines for Cancer Therapy

edited by Takashi Morisaki

submission deadline 30 Aug 2026 | Viewed by 72 | Submission Open

Keywords: neoantigens; vaccine; dendritic cells; cancer; immunotherapy; priming; CTL; helper T cells

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Gastrointestinal Malignancy: Epidemiology and Risk Factors

edited by Patrick Okolo and Chengu Niu

submission deadline 31 Aug 2026 | 8 articles | Viewed by 31407 | Submission Open

Keywords: gastrointestinal cancer; epidemiology; risk factors; molecular markers; genetic factors; therapeutic advancements; prevention strategies; public health; interdisciplinary approaches; clinical impact

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Advancing Horizons in Colorectal Surgery: Innovative Approaches and Outcomes

edited by Petros I. Bangeas and Vasileios N. Papadopoulos

submission deadline 31 Aug 2026 | 4 articles | Viewed by 17016 | Submission Open

Keywords: colorectal surgery; postoperative pain; surgical site infections; anastomotic leaks; minimally invasive techniques; robotic surgery

(This special issue belongs to the Section Cancer Therapy)

Advancements in “Cancer Biomarkers” for 2025–2026

edited by

Maxim V. Berezovski

submission deadline 31 Aug 2026 | 10 articles | Viewed by 15060 | Submission Open

Keywords: RNA biomarkers; miRNA biomarkers; DNA biomarkers; cell-free DNA (cfDNA); protein biomarkers; metabolomic biomarkers; mutational biomarkers; circulating tumor cells (CTCs); tumor-derived extracellular vesicle (tEV) biomarkers; cellular biomarkers; imaging biomarkers; clinical biomarkers; biomarkers of drug response; biomarkers of genetic predisposition to cancer; epigenetic biomarkers; biomarkers of cancer outcomes; mass spectrometry; next-generation sequencing (NGS); flow cytometry; positron emission tomography (PET); computed tomography (CT); magnetic resonance imaging (MRI); X-rays; ultrasound; electrocardiography (ECG/EKG); endoscopy; biopsy; pulmonary function tests (PFTs); histopathology; cytopathology; immunohistochemistry (IHC); in situ hybridization (ISH); fluorescence in situ hybridization (FISH); liquid biopsy; electron microscopy; digital pathology and image analysis

(This special issue belongs to the Section Cancer Biomarkers)

Feature Review Paper Special Issue in Section Molecular Cancer Biology

edited by

Donat Kögel

submission deadline 31 Aug 2026 | 3 articles | Viewed by 9026 | Submission Open

Keywords: molecular biology; cell biology; cancer; tumor; cancer cell

(This special issue belongs to the Section Molecular Cancer Biology)

Prevention, Early Detection, and Surgical Oncology in Hepatocellular Carcinoma, Pancreatic Cancer, and Gastrointestinal Cancer

edited by

Mingyao Chen

and

Kuang-Chun Hu

submission deadline 31 Aug 2026 | 3 articles | Viewed by 4625 | Submission Open

Keywords: early image detection in cancer; biomarker of cancer; surgical treatment; gastrointestinal cancer

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Cancer Stem Cells: The Origin of Tumor Relapse and Metastasis

edited by

Ming Tan

and

Evgeniy V. Denisov

submission deadline 31 Aug 2026 | 2 articles | Viewed by 4157 | Submission Open

Keywords: metastasis; cancer stem cell; tumor microenvironment; tumor heterogeneity; plasticity; immune evasion; therapeutic resistance

(This special issue belongs to the Section Molecular Cancer Biology)

The Genetic Analysis and Clinical Therapy in Lung Cancer: 2nd Edition

edited by

Francesca Colombo

and Frullanti Elisa

submission deadline 31 Aug 2026 | 1 articles | Viewed by 2787 | Submission Open

Keywords: lung cancer; biomarkers; genetic variants; innovative technologies; targeted therapy; immunotherapy; personalized therapy; survival; liquid biopsy pharmacogenomics

(This special issue belongs to the Section Cancer Therapy)

CAR T-Cell Therapy and Multiple Myeloma

edited by Jo Caers

submission deadline 31 Aug 2026 | 1 articles | Viewed by 706 | Submission Open

Keywords: multiple myeloma; CAR-T immunotherapy; toxicity; efficacy; tumor models; safety

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Displaying special issue 951-1000 on page 20 of 24.

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