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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Clinical Applications of Precision Diagnosis for Thyroid Cancers and Its Clinical Use for Treatments Choice

edited by

Maria Trovato

, Silvia Martina Ferrari and

Fausto Famà

submission deadline 30 Jun 2026 | 2 articles | Viewed by 3423 | Submission Open

Keywords: thyroid cancer; precision diagnosis; clinical management; molecular tests; molecular therapeutic targets; thyroid cancer epidemiology; artificial intelligence; health inequalities

(This special issue belongs to the Section Clinical Research of Cancer)

New Strategies for the Treatment of Melanoma and Non-Melanoma Skin Cancer

edited by

Yoshihide Asano

and

Taku Fujimura

submission deadline 30 Jun 2026 | 2 articles | Viewed by 3337 | Submission Open

Keywords: melanoma; non-melanoma skin cancer; immunotherapy; anti-PD-1 antibody; BRAF/MEK inhibitors; racial differences; prognosis

(This special issue belongs to the Section Cancer Therapy)

Advances in Neurofibromatosis

edited by Yunjia Chen and Yulong Fu

submission deadline 30 Jun 2026 | 2 articles | Viewed by 3316 | Submission Open

Keywords: neurofibromatosis; schwannomatosis; NF1; NF2; SMARCB1; LZTR1

(This special issue belongs to the Section Molecular Cancer Biology)

Advances in Blood Cancers: How We Define Success

edited by

Stefano Molica

and

David Allsup

submission deadline 30 Jun 2026 | 1 articles | Viewed by 3304 | Submission Open

Keywords: blood cancers; research-driven advancements; cure rates; novel agents

(This special issue belongs to the Section Cancer Therapy)

Innovations in Microsurgical Techniques for Breast Cancer Reconstruction

edited by

Babak J. Mehrara

and Robert J. Allen

submission deadline 30 Jun 2026 | 3 articles | Viewed by 3267 | Submission Open

Keywords: breast reconstruction; autologous breast reconstruction; DIEP flap; robotic DIEP flap; sensibility; alternative flaps; post-mastectomy pain; PAP flap; LAP flap; GAP flap; LTP flap; perforator flap; latissimus flap; fat grafting; nerve repair

(This special issue belongs to the Section Methods and Technologies Development)

Palliative Radiotherapy for Cancer

edited by Rebecca Wong

submission deadline 30 Jun 2026 | 2 articles | Viewed by 3183 | Submission Open

Keywords: symptom relief; symptom control; radiation medicine; radiotheranostics; theranostics; external beam radiotherapy; palliation; oligometastases; oligoprogression; systematic reviews and meta-analyses; patient reported outcomes; abscopal effect; combined modality; education; clinical practice

(This special issue belongs to the Section Cancer Therapy)

Technical and Technological Innovations in Head and Neck Cancer Surgery

edited by Marta Filauro

submission deadline 30 Jun 2026 | 1 articles | Viewed by 3052 | Submission Open

Keywords: head and neck; squamous cell carcinoma; larynx; oral cavity; free flap; exoscope; TORS

(This special issue belongs to the Section Methods and Technologies Development)

Recent Advances in Peritoneal Carcinomatosis

edited by Neda Dadgar and Patrick L. Wagner

submission deadline 30 Jun 2026 | 1 articles | Viewed by 2837 | Submission Open

Keywords: peritoneal carcinomatosis; tumor microenvironment; immunotherapy biomarkers; microbiome– host interactions; epithelial– mesenchymal transition (emt); intra-cavitary therapies; cytokine signaling; translational oncology; multiomics profiling; organoid

(This special issue belongs to the Section Clinical Research of Cancer)

Radioimmunotherapy, Neoadjuvant Immunotherapy, and Adjuvant Immunotherapy for Cancer

edited by

Rashidul Alam Mahumud

submission deadline 30 Jun 2026 | 1 articles | Viewed by 2689 | Submission Open

Keywords: immunotherapy; radioimmunotherapy; neoadjuvant immunothearpy; radiopharmaceuticals

(This special issue belongs to the Section Cancer Therapy)

Clinical Pathology of Lung Cancer (2nd Edition)

edited by

Letizia Gnetti

submission deadline 30 Jun 2026 | 2 articles | Viewed by 2601 | Submission Open

Keywords: lung cancer; pathology; diagnosis; treatment; targeted therapies; immunotherapy

(This special issue belongs to the Section Clinical Research of Cancer)

Feature Review Papers on Cancer Epidemiology, Disparities, and Prevention

edited by Adam Barsouk

submission deadline 30 Jun 2026 | 1 articles | Viewed by 2553 | Submission Open

Keywords: epidemiology; disparities; oncology; cancer; prevention

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Molecular Pathology and Human Cancers

edited by Stefano Marletta, Alessandro Russo and Giuliana Pavone

submission deadline 30 Jun 2026 | 2 articles | Viewed by 2482 | Submission Open

Keywords: molecular pathology; cancer pathogenesis; targeted therapy; personalized medicine; cancer signaling

(This special issue belongs to the Section Cancer Pathophysiology)

Advances in Breast Cancer Imaging: From Detection to Personalized Diagnosis

edited by

Nuno Matela

and

Ana Margarida Mota

submission deadline 30 Jun 2026 | 1 articles | Viewed by 2397 | Submission Open

Keywords: breast cancer imaging; artificial intelligence; radiomics; deep learning; personalized diagnosis; multimodal imaging; predictive modeling; early detection; treatment response; clinical applications

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Urological Cancer: Epidemiology and Genetics

edited by Ilir Agalliu and Evan Kovac

submission deadline 30 Jun 2026 | 1 articles | Viewed by 2313 | Submission Open

Keywords: environmental factors; lifestyle; genetic susceptibility; biomarkers; prostate cancer; bladder cancer; kidney cancer

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Plasma and Cancer Treatment

edited by

Michael Keidar

and

Vikas Soni

submission deadline 30 Jun 2026 | 2 articles | Viewed by 2078 | Submission Open

Keywords: cold atmospheric plasma (CAP); cancer treatment; plasma medicine; reactive oxygen species (ROS); apoptosis; tumor; non-thermal plasma; plasma oncology; cancer and molecular biology; clinical translation; in vivo/preclinical

(This special issue belongs to the Section Cancer Therapy)

Challenges and New Developments in the Diagnosis and Treatment of Sarcoma

edited by

Xiaolan Feng

submission deadline 30 Jun 2026 | 1 articles | Viewed by 2065 | Submission Open

Keywords: bone and soft tissue sarcoma; prognostic and predictive biomarker; transcriptomic/genomic profiling; immunotherapy; targeted treatment

(This special issue belongs to the Section Cancer Therapy)

New Insights in the Management of Resectable Esophageal Malignancy

edited by

Tania Triantafyllou

and Dimitrios A. Theodorou

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1988 | Submission Open

Keywords: esophageal cancer; perioperative chemotherapy; radiotherapy; immunotherapy; radical surgical resection

(This special issue belongs to the Section Methods and Technologies Development)

Cutaneous Metastases: State-of-the-Art Research and Management

edited by Marios N. Papadakis and

Dimitra Koumaki

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1941 | Submission Open

Keywords: cutaneous metastases; cancer skin metastasis; metastatic skin lesions; diagnosis of cutaneous metastases; oncology; skin oncology; patient outcomes

(This special issue belongs to the Section Cancer Metastasis)

Genetic Alterations and Features in the Development of Gastrointestinal Cancer

edited by

Alexandra Voutsina

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1870 | Submission Open

Keywords: gastrointestinal cancers; genetic alteration; epigenetic regulation; the mechanism of tumorigenesis; precision treatment

(This special issue belongs to the Section Molecular Cancer Biology)

Advances in Radiology for the Detection, Diagnosis, and Management of Breast Cancer

edited by Takouhie Catherine Maldjian and Mary M. Salvatore

submission deadline 30 Jun 2026 | 3 articles | Viewed by 1766 | Submission Open

Keywords: breast cancer; radiology; breast imaging; mammography; MRI; ultrasound; AI; radiomics; diagnosis; treatment response; image-guided biopsy

(This special issue belongs to the Section Methods and Technologies Development)

Surgery in Metastatic Cancer (2nd Edition)

edited by

Ulrich Ronellenfitsch

submission deadline 30 Jun 2026 | 2 articles | Viewed by 1714 | Submission Open

Keywords: metastatic cancer; surgery; metastasectomy; indication; timing

(This special issue belongs to the Section Cancer Therapy)

Unveiling the Complexity of Hepato-Biliary-Pancreatic Cancers: From Pathogenesis to Management

edited by

Stefano Cacciatore

and Luiz Zerbini

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1515 | Submission Open

Keywords: hepatocellular carcinoma (HCC); cholangiocarcinoma; pancreatic ductal adenocarcinoma (PDAC); tumour microenvironment; molecular biomarkers; therapeutic resistance; cancer immunotherapy; early cancer detection; precision oncology; targeted therapy

(This special issue belongs to the Section Clinical Research of Cancer)

Recent Advances in Epidemiology of Childhood Cancer

edited by Rafael Peris-Bonet,

Rebeca Ramis

and Adela Cañete

submission deadline 30 Jun 2026 | 2 articles | Viewed by 1412 | Submission Open

Keywords: childhood cancer epidemiology; childhood cancer registries; environmental causes of childhood cancer; genetic epidemiology; molecular epidemiology; survival of children with cancer; quality of life; social determinants and inequalities; information technologies and statistical innovations

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

PARP Inhibitors in Cancer Therapy

edited by

Jie Jiang

and

Fu Gui

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1356 | Submission Open

Keywords: PARP inhibitors; cancer therapy; DNA damage repair; drug discovery

(This special issue belongs to the Section Cancer Therapy)

Neurofibromatosis Type 1 (NF1) Related Tumors (2nd Edition)

edited by

Daochun Sun

and

Sameer Farouk Sait

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1318 | Submission Open

Keywords: NF1; tumorigenesis; cancer stem cells; targeted therapy; tumor microenvironment; epigenetics; case report; metastasis; clinical trials

(This special issue belongs to the Section Tumor Microenvironment)

Targeted Radiotracers for Molecular Imaging and Therapy in Cancer

edited by

Vladimir Tolmachev

and

Maryam Oroujeni

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1259 | Submission Open

Keywords: theranostic; radionuclide molecular imaging; targeted therapy; specificity; selectivity; personalized medicine; radiopharmaceuticals

(This special issue belongs to the Section Methods and Technologies Development)

Advances in Pancreatic Cancer: Exploring Biomarkers and Prognostic Predictors

edited by

Makoto Abue

submission deadline 30 Jun 2026 | 2 articles | Viewed by 1225 | Submission Open

Keywords: pancreatic cancer; biomarkers; diagnosis; prognosis; liquid biopsy; proteomics; metabolomics; tumor microenvironment; genetic aberrations/mutations; inflammatory markers

(This special issue belongs to the Section Cancer Biomarkers)

Understanding the Molecular Basis and Immunobiology of Renal Cell Carcinoma and Exploring Novel Therapeutic Strategies

edited by

Heba Khella

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1199 | Submission Open

Keywords: renal cell carcinoma; molecular basis; immunobiology; tumor microenvironment; immunotherapy; targeted therapy; metastasis; precision medicine; biomarkers; non-coding RNA; miRNA; prognosis; molecular diagnostics; translational research

(This special issue belongs to the Section Cancer Therapy)

Soft Tissue Sarcomas—New Diagnostic and Therapeutic Perspectives Through Clinical Genomic Profiling

edited by

Ewa Koscielniak

and

Monika Sparber-Sauer

submission deadline 30 Jun 2026 | 1 articles | Viewed by 980 | Submission Open

Keywords: soft tissue sarcoma; molecular profiling; cancer genomics; personalized medicine

(This special issue belongs to the Section Cancer Therapy)

Advances in Neoadjuvant Therapy for Urologic Cancer

edited by Carlo Messina

submission deadline 30 Jun 2026 | 1 articles | Viewed by 960 | Submission Open

Keywords: neoadjuvant treatment; bladder cancer; prostate cancer; renal cell carcinoma; penile cancers; immunotherapy; antibody– drug conjugates

(This special issue belongs to the Section Cancer Therapy)

Non-Coding RNAs and Extracellular Vesicles in Cancer Crosstalk: Diagnostic and Therapeutic Implications 2nd Edition

edited by

Simona Taverna

and

Giuseppe Cammarata

submission deadline 30 Jun 2026 | 1 articles | Viewed by 895 | Submission Open

Keywords: extracellular vesicles; exosomes; cancer; inflammation; non-coding RNA; microRNAs; circular-RNAs; PIWI-RNAs; lnc-RNAs

(This special issue belongs to the Section Cancer Therapy)

Modern Neurosurgical Management of Gliomas

edited by

Arthur Wagner

and

Chiara Negwer

submission deadline 30 Jun 2026 | 2 articles | Viewed by 892 | Submission Open

Keywords: precision medicine; personalized oncological surgery; intraoperative imaging; fluorescence-guided surgery; intraoperative histopathology; liquid biopsy; minimally invasive oncological surgery; radiosurgery

(This special issue belongs to the Section Cancer Therapy)

Advanced Research in Surgical Treatment for Spinal Tumors

edited by Alessandro Gasbarrini, Stefano Bandiera and

Giuseppe Tedesco

submission deadline 30 Jun 2026 | 1 articles | Viewed by 890 | Submission Open

Keywords: spine oncology; primary tumors; metastatic tumors; spondylectomy; en bloc resection; minimally invasive surgery; anterior reconstruction; biomaterials; radiosurgery; electrochemotherapy

(This special issue belongs to the Section Cancer Therapy)

Pleural Mesothelioma: From Diagnosis to Treatment

edited by

Giovanni Luca Ceresoli

and

Paolo Andrea Zucali

submission deadline 30 Jun 2026 | 1 articles | Viewed by 848 | Submission Open

Keywords: pleural mesothelioma; histological classification; molecular characteristics; immunotherapy; chemotherapy; radiotherapy; surgery; targeted therapy; emerging therapies

(This special issue belongs to the Section Cancer Therapy)

Contemporary Management for Gallbladder Cancer: From Diagnosis to Treatment (2nd Edition)

edited by Hiromichi Ito

submission deadline 30 Jun 2026 | 1 articles | Viewed by 727 | Submission Open

Keywords: gallbladder cancer; radical cholecystectomy; adjuvant chemotherapy; neoadjuvant therapy; incidental gallbladder cancer; multidisciplinary management; preoperative staging

(This special issue belongs to the Section Cancer Therapy)

The Role of Anatomical Resections in Secondary Lung Cancer: Indications, Techniques, and Outcomes

edited by

Andrea Dell'Amore

and

Alessio Campisi

submission deadline 30 Jun 2026 | 1 articles | Viewed by 710 | Submission Open

Keywords: anatomical resections; segmentectomy; lobectomy; secondary lung cancer; pulmonary metastases; thoracic surgery; minimally invasive surgery; surgical outcomes; lung neoplasms; personalized treatment

(This special issue belongs to the Section Clinical Research of Cancer)

Radiation Therapy in Oncology

edited by Jerzy Wydmański

submission deadline 30 Jun 2026 | 1 articles | Viewed by 659 | Submission Open

Keywords: radiotherapy; radiation injury; systemic therapy; immunotherapy; cancer; concurrent chemoradiotherapy; stereotactic radiotherapy

(This special issue belongs to the Section Cancer Therapy)

Updates on Anti-Cancer Drug Research

edited by

Ana Luísa De Sousa-Coelho

and Mónica Fernandes

submission deadline 30 Jun 2026 | 1 articles | Viewed by 627 | Submission Open

Keywords: anti-cancer drug research; drug resistance; biomarkers; pharmacogenomics; single-cell RNA sequencing; non-coding RNAs; multi-omics data

(This special issue belongs to the Section Cancer Drug Development)

Advanced Segmentation in Multimodal Nuclear Imaging of Solid Tumors and Lymphomas: Tools, Challenges, and Clinical Integration

edited by

Ken Kudura

and Robert Förster

submission deadline 30 Jun 2026 | 1 articles | Viewed by 543 | Submission Open

Keywords: multimodal nuclear imaging; artificial intelligence in nuclear medicine; radiomics in nuclear medicine; tumor segmentation; segmentation techniques; segmentation tools; outcome prediction; radioligand therapy

(This special issue belongs to the Section Methods and Technologies Development)

Immunotherapy Approaches in Breast Cancer Treatment (2nd Edition)

edited by Yi Huang and

Bing Li

submission deadline 30 Jun 2026 | 1 articles | Viewed by 466 | Submission Open

Keywords: breast cancer progression; immunotherapy; combination therapy; drug discovery; antitumor immunity; tumor immune microenvironment; biomarkers and clinical trials

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Surgical Perspectives in Lung Cancer: From Technique to Outcome

edited by Takahiro Homma and Hyun Koo Kim

submission deadline 30 Jun 2026 | Viewed by 428 | Submission Open

Keywords: minimally invasive surgery; enhanced recovery after surgery (ERAS); uniportal VATS; robotic-assisted thoracic surgery (RATS); surgical education; perioperative management; energy devices; lung cancer surgery

(This special issue belongs to the Section Cancer Therapy)

Research and Treatment of Hepatocellular Carcinoma

edited by Chung Cheung Thomas Yau

submission deadline 30 Jun 2026 | 1 articles | Viewed by 426 | Submission Open

Keywords: hepatobiliary cancer; biomarker; immunotherapy; targeted therapy; combination treatments

(This special issue belongs to the Section Cancer Therapy)

Recent Updates on Treatment of Uveal Melanoma

edited by Richard D. Carvajal, Shaheer Khan and Brian Peter Marr

submission deadline 30 Jun 2026 | Viewed by 425 | Submission Open

Keywords: uveal melanoma; systemic therapies; surgical innovations; radiotherapy; genetic and molecular insights; translational research

(This special issue belongs to the Section Cancer Therapy)

Innovative Treatments Based on Genomic Aberrations in Leukemia and Lymphoma

edited by

Vera Ulrike Bacher

and

Ashwini K. Yenamandra

submission deadline 30 Jun 2026 | Viewed by 371 | Submission Open

Keywords: leukemia; lymphoma; AI and predictive modeling; MRD; B-ALL; DLBCL; genomics; treatment

(This special issue belongs to the Section Cancer Therapy)

Cancer Inhibitory Receptors: Targeting Tumor Microenvironment Therapeutically

edited by

Vaishali Aggarwal

and Alok Kumar

submission deadline 30 Jun 2026 | Viewed by 355 | Submission Open

Keywords: immune checkpoint inhibitors; immunotherapy; tumor microenvironment; inhibitory receptors; immune system; T cells; malignant cells; therapeutic targets

(This special issue belongs to the Section Cancer Therapy)

Proton and Light Ion Therapy for Cancer

edited by Oliver Jäkel

submission deadline 30 Jun 2026 | Viewed by 332 | Submission Open

Keywords: novel beam delivery concepts; image guidance; adaptive therapy; in vivo monitoring; radiobiological studies with protons and light ions; clinical studies; outcome reports

(This special issue belongs to the Section Cancer Therapy)

Research Challenges in Adolescent and Young Adult Cancer

edited by

Lorna A. Fern

and Jeremy Lewin

submission deadline 30 Jun 2026 | Viewed by 332 | Submission Open

Keywords: adolescents and young adults; research enrollment and retention; clinical trials; access; barriers

(This special issue belongs to the Section Pediatric Oncology)

Role of BCL-2 Family Proteins in Cancer: Therapeutic Advancements and Challenges

edited by Sajid Khan

submission deadline 30 Jun 2026 | Viewed by 325 | Submission Open

Keywords: BCL-2 family proteins; apoptosis; BH3 mimetics; thrombocytopenia; proteolysis-targeting chimeras; drug resistance; combination therapy; targeted drug delivery

(This special issue belongs to the Section Cancer Therapy)

Cancer Disparities and Health Equity: Challenges, Insights, and Transformative Strategies

edited by

Mandi Pratt-Chapman

and Jane Ussher

submission deadline 30 Jun 2026 | Viewed by 321 | Submission Open

Keywords: scientific censorship; terminated grants; identity politics and health; LGBTQI+ cancer health equity; LGBTQI+ cancer survivorship and care

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Signaling Networks Controlling Ovarian Cancer Progression and Response to Therapy

edited by

Luca Tamagnone

and Roberta Mastrantonio

submission deadline 30 Jun 2026 | Viewed by 315 | Submission Open

Keywords: ovarian cancer; patient-derived models; mesothelium; ascites; immunotherapy; chemotherapy; drug resistance; metastasis; peritoneum; p53; BRCA; signaling pathway; metabolism

(This special issue belongs to the Section Tumor Microenvironment)

Displaying special issue 751-800 on page 16 of 25.

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