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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Adoptive Cell Therapy for Cancer
edited by Andrew Furness
submission deadline 30 Nov 2026 | Viewed by 39 | Submission Open
Keywords: CAR-T cells; adoptive cell therapy; tumor microenvironment; immunotherapy; translational oncology
Update in Pathology of Gynaecologic Cancer
edited by
submission deadline 30 Nov 2026 | Viewed by 30 | Submission Open
Keywords: gynaecological; cancer; pathology; diagnosis
(This special issue belongs to the Section Cancer Pathophysiology)
HMGA Oncoproteins in Cancer
edited by and Sabrina Battista
submission deadline 30 Nov 2026 | Viewed by 16 | Submission Open
Keywords: HMGA1; HMGA2; chromatin architecture; oncogenic signaling; tumor progression; biomarkers; therapeutic targeting
(This special issue belongs to the Section Molecular Cancer Biology)
Innovations and Current Evidence in Radiotherapy for Urological Cancers
edited by
submission deadline 30 Nov 2026 | Viewed by 14 | Submission Open
Keywords: radiotherapy; urological cancer; prostate cancer; kidney cancer; urothelial cancer; testicular cancer; penile cancer; palliative; metastases; salvage
(This special issue belongs to the Section Cancer Therapy)
New Advances of Brain Metastasis in Oncology submission deadline 5 Dec 2026 | Viewed by 15 | Submission Open
Keywords: brain mets; BBB; brain microenvironment; molecular mechanism; immune; cytokines; drugs
(This special issue belongs to the Section Cancer Metastasis)
Advances in Hormone-Based Breast Cancer Treatment submission deadline 5 Dec 2026 | Submission Open
Keywords: DNA damage; checkpoint inhibitor; retinoid; PARP1; estrogen/estrogen receptors; androgen/androgen receptors; glucocorticoid/glucocorticoid receptors; tumor classification
(This special issue belongs to the Section Cancer Therapy)
Clinical Treatment and Prognostic Factors of Urologic Cancer
edited by
submission deadline 15 Dec 2026 | 13 articles | Viewed by 40005 | Submission Open
Keywords: prostate cancer; bladder cancer; urothelial carcinoma; upper urinary tract tumors; kidney cancer; renal cell carcinoma; testicular tumors; molecular markers; diagnosis; systemic treatment
(This special issue belongs to the Section Cancer Therapy)
The Evolving Landscape of Squamous Cell Carcinoma of the Anal Canal: State of the Art, Current Challenges and Future Perspectives
edited by and Francesco Vasuri
submission deadline 15 Dec 2026 | Viewed by 78 | Submission Open
Keywords: squamous cell anal carcinoma; anal cancer; HIV; HPV
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Treatment-Induced Metabolic and Inflammatory Responses in Cancer
edited by
submission deadline 15 Dec 2026 | Viewed by 22 | Submission Open
Keywords: radiation therapy; chemotherapy; immunotherapy; normal tissue toxicity; metabolic reprogramming; chronic inflammation; lipid dysregulation; treatment resistance; inflammatory signaling
Cancer Genetics and Epigenetics: Their Roles and Clinical Implications (2nd Edition)
edited by and
submission deadline 20 Dec 2026 | 1 articles | Viewed by 577 | Submission Open
Keywords: cancer genetics; cancer epigenetics; carcinogenesis; cancer prognosis; cancer therapeutics; genetic mutations; DNA methylation; histone modifications; RNA methylation
(This special issue belongs to the Section Molecular Cancer Biology)
Hematological Malignancies: From Translational Discoveries to Clinical Trends
edited by and Charyguly Annageldiyev
submission deadline 20 Dec 2026 | Viewed by 108 | Submission Open
Keywords: hematological malignancies; leukemia; lymphoma; myeloma; translational research; preclinical studies; clinical outcomes; molecular biomarkers; targeted therapy; precision medicine
(This special issue belongs to the Section Cancer Therapy)
The State of the Art in Cardio-Oncology submission deadline 20 Dec 2026 | Viewed by 88 | Submission Open
Keywords: cardio-oncology; cardiotoxicity; cancer therapeutics; reverse cardio-oncology; precision cardio-oncology; genetics in cardio-oncology
Retroviruses and Cancer Development: Molecular Mechanisms and Therapeutic Prospects
edited by Donna D'Agostino and
submission deadline 20 Dec 2026 | Viewed by 27 | Submission Open
Keywords: retroviruses; cancer; ERV; antivirals; persistent infection
(This special issue belongs to the Section Infectious Agents and Cancer)
Tumor–Microbiota Crosstalk: Immune Modulation and Resistance to Cancer Therapies submission deadline 25 Dec 2026 | Viewed by 59 | Submission Open
Keywords: tumor– microbiota; immune modulation; cancer therapies
(This special issue belongs to the Section Infectious Agents and Cancer)
Cancer Cell Death and Immune Response
edited by Seema Singh and
submission deadline 25 Dec 2026 | Viewed by 55 | Submission Open
Keywords: immunogenic cell death; tumor immunity; epigenetics; apoptosis; tumor microenvironment; biomarkers
(This special issue belongs to the Section Molecular Cancer Biology)
Epitranscriptomics and the Tumor Microenvironment
edited by
submission deadline 25 Dec 2026 | Viewed by 16 | Submission Open
Keywords: epitranscriptomics; tumor microenvironment; immune
(This special issue belongs to the Section Tumor Microenvironment)
Immunotherapy with Checkpoint Inhibitors for Non-Small-Cell Lung Cancer (2nd Edition) submission deadline 30 Dec 2026 | Viewed by 159 | Submission Open
Keywords: immune-checkpoint inhibitors; non-small cell lung cancer; neoadjuvant therapy; adjuvant therapy; primary resistance; acquired; resistance; biomarkers; immune-related adverse events
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Nanomedicine’s Role in Oncology submission deadline 31 Dec 2026 | 1 articles | Viewed by 2482 | Submission Open
Keywords: nanomedicine; oncology; interventional oncology; nanotechnology development; cancer diagnosis; cancer treatment; cancer imaging
(This special issue belongs to the Section Methods and Technologies Development)
Multiple Myeloma—Biology, Diagnosis, Treatment and Prognosis (2nd Edition)
edited by
submission deadline 31 Dec 2026 | 2 articles | Viewed by 2407 | Submission Open
Keywords: multiple myeloma; bone marrow microenvironment; minimal residual disease; mass spectrometry; flow cytometry; CAR-T; bispecific agents; genomic alterations
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Advances in Cancer Survival Analysis
edited by , Jianguang Ji and
submission deadline 31 Dec 2026 | 1 articles | Viewed by 1099 | Submission Open
Keywords: cancer burden; cancer survival; epidemiology; survival analysis methodology; cancer screening; cancer control; cancer prognosis; cancer data mining
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
CancersScape: Spatial Biology of the Tumor Ecosystem
edited by and Sammy Ferri-Borgogno
submission deadline 31 Dec 2026 | Viewed by 866 | Submission Open
Keywords: cancer; health; tumor microenvironment; spatial biology; cancer diagnosis; cancer drug discovery; Omics
Cancer Patient Cognitive Disorders: Causes, Prevention and Management submission deadline 31 Dec 2026 | Viewed by 419 | Submission Open
Keywords: delirium; brain health; cognitive impairment; cancer; etiology; risk stratification; screening tool; biomarkers; postoperative delirium; pain management; delirium prevention; management; outcomes
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Cancer Cell Vulnerabilities on Pathways Regulating the Cell Cycle
edited by
submission deadline 31 Dec 2026 | Viewed by 349 | Submission Open
Keywords: cell cycle; signaling pathway; precision medicine
(This special issue belongs to the Section Molecular Cancer Biology)
Cancer Cell Communications, Metastasis and Survival in the Host Microenvironment—2nd Edition
edited by and
submission deadline 31 Dec 2026 | Viewed by 212 | Submission Open
Keywords: cancer cells; cancer cell-derived cytokines; host microenvironment; metastasis; gene alteration; signaling pathways; host cells
(This special issue belongs to the Section Tumor Microenvironment)
Tumor Microenvironment: Cellular Dynamics, Molecular Players, and Mechanisms of Therapy Resistance
edited by , Angeliki Ditsiou and
submission deadline 31 Dec 2026 | Viewed by 202 | Submission Open
Keywords: tumor microenvironment (TME); cellular interactions; molecular mechanisms; resistance mechanisms; signaling pathways; translational cancer therapy
(This special issue belongs to the Section Tumor Microenvironment)
Tumor Suppressor Genes and Oncogenes: Genome-Wide Insights into Cancer Biology
edited by
submission deadline 31 Dec 2026 | Viewed by 139 | Submission Open
Keywords: tumor suppressor genes; oncogenes; cancer; genome analysis; cancer mutations; DNA methylation; histone modification; cancer progression; oncogenesis
(This special issue belongs to the Section Molecular Cancer Biology)
Cutaneous Lymphomas: Present and Future
edited by
submission deadline 31 Dec 2026 | Viewed by 130 | Submission Open
Keywords: cutaneous lymphoma; T-cell lymphoma; B-cell lymphoma; mycosis fungoides; Sé zary syndrome; tumor microenvironment
Laparoscopic and Robotic Surgery for Gastrointestinal and Hepato-Pancreato-Biliary Cancers
edited by
submission deadline 31 Dec 2026 | Viewed by 105 | Submission Open
Keywords: minimally invasive surgery; laparoscopic surgery; robotic surgery; gastrointestinal cancers; hepato-pancreato-biliary cancers; neoadjuvant therapy; adjuvant therapy; outcomes
(This special issue belongs to the Section Clinical Research of Cancer)
Minimally Invasive Surgery in Gynecologic Cancers
edited by Pawel Sadlecki
submission deadline 31 Dec 2026 | Viewed by 91 | Submission Open
Keywords: minimally invasive surgery; gynecologic oncology; laparoscopy; robotic-assisted surgery; surgical outcomes; endometrial cancer; cervical cancer; ovarian cancer; surgical innovation
(This special issue belongs to the Section Cancer Therapy)
Molecular Advances in Lung Cancer: From Pathogenesis to Precision Therapy (2nd Edition) submission deadline 31 Dec 2026 | Viewed by 81 | Submission Open
Keywords: lung cancer molecular biology; targeted therapy; precision medicine; biomarkers; therapeutic resistance
(This special issue belongs to the Section Molecular Cancer Biology)
Pathogenesis and Treatment Strategies in Multiple Myeloma: From Basic Research to Real Life: 2nd Edition
edited by Shingen Nakamura
submission deadline 31 Dec 2026 | Viewed by 73 | Submission Open
Keywords: myeloma bone disease; denosumab; bisphosphonate; infectious complication; proteasome inhibitor; IMiDs; anti-CD38 antibody; venetoclax; immunotherapy
(This special issue belongs to the Section Cancer Therapy)
Psycho-Social Pathways in Cancer Care: From Fear of Recurrence to Resilience and Quality of Life
edited by , and Cosimo Rupe
submission deadline 31 Dec 2026 | Viewed by 73 | Submission Open
Keywords: fear of cancer recurrence; oncology; cancer survivorship; quality of life; psychological and behavioral interventions
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Serum Biomarkers to Monitor Cancer Progression and Response to Therapy
edited by
submission deadline 31 Dec 2026 | Viewed by 67 | Submission Open
Keywords: biomarkers; cancer; tumor
(This special issue belongs to the Section Tumor Microenvironment)
Innovations in Cutaneous Oncology and Dermatologic Surgery: Translating Mechanisms into Practice
edited by Paulo Filipe and Maria Catorze
submission deadline 31 Dec 2026 | Viewed by 55 | Submission Open
Keywords: cutaneous oncology; dermatologic surgery; mohs micrographic surgery; immunotherapy; hedgehog pathway; translational research; skin cancer; digital innovation
(This special issue belongs to the Section Cancer Therapy)
Overcoming the Barriers: Cellular and Molecular Pathology of Pancreatic Cancer
edited by
submission deadline 31 Dec 2026 | Viewed by 39 | Submission Open
Keywords: pancreatic cancer; metastasis; tumor microenvironment; tumor metabolism; tumor immunity
(This special issue belongs to the Section Molecular Cancer Biology)
Advancing Therapeutic Strategies for Neuroendocrine Tumors: Towards Personalized and Multidisciplinary Care
edited by
submission deadline 31 Dec 2026 | Viewed by 29 | Submission Open
Keywords: neuroendocrine tumor; neuroendocrine carcinoma; multidisciplinary care; PRRT; hepatic embolization; tumor debulking; targeted therapy; lung carcinoid
(This special issue belongs to the Section Cancer Therapy)
Global Perspectives on the Epidemiology and Management of Early-Onset Cancers
edited by
submission deadline 31 Dec 2026 | Viewed by 14 | Submission Open
Keywords: early-onset cancer; adolescent and young adult cancer (AYA); early-onset breast cancer; early-onset colorectal cancer; early-onset pancreatic cancer; early-onset thyroid cancer; early-onset melanoma; early-onset gastrointestinal cancers; early-onset hematological cancers; early-onset cancers of reproductive organs
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Evolving Landscape in the Management of Liver Malignancies
edited by Ioannis A. Ziogas and
submission deadline 1 Jan 2027 | Viewed by 59 | Submission Open
Keywords: liver cancer; hepatocellular carcinoma; cholangiocarcinoma; colorectal liver metastasis; liver resection; liver transplantation; transplant oncology; locoregional therapies; immunotherapy; molecular profiling
Resistance in Lung Cancer
edited by Mohamed Gadelkarim
submission deadline 15 Mar 2027 | Viewed by 235 | Submission Open
Keywords: lung cancer; SCLC; NSCLC; drug resistance; genetic mutations; tumor microenvironment; EMT; biomarkers; targeted therapy; immunotherapy
(This special issue belongs to the Section Cancer Therapy)
The Critical Intersection of Tobacco Use and Cancer Care
edited by Irene Tamí-Maury
submission deadline 15 Mar 2027 | Viewed by 90 | Submission Open
Keywords: cancer; oncology settings; smoking; tobacco use; prevention; cessation
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
New Statistical and Machine Learning Methods for Cancer Research
edited by Anjishnu Banerjee
submission deadline 20 May 2027 | Viewed by 167 | Submission Open
Keywords: statistical methods; machine learning; “Omics” research; adaptive clinical trials; drug development; personalized cancer therapies
(This special issue belongs to the Section Cancer Informatics and Big Data)
Cancer Causes and Control submission deadline 1 Dec 2027 | 4 articles | Viewed by 13926 | Submission Open
Keywords: cancer burden; risk factors for cancer; primary cancer prevention; secondary cancer prevention; tertiary cancer prevention; quality of life for people who have cancer; population-based cancer registry
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
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