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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Long-Read Sequencing in Cancer (2nd Edition)

edited by

Luca Ermini

and Patrick Driguez

submission deadline 30 Jun 2026 | Viewed by 105 | Submission Open

Keywords: long-read sequencing; cancer genetics; genomics; transcriptomics; methylomics; cancer research

(This special issue belongs to the Section Molecular Cancer Biology)

Prostate Cancer Pathology and Grade

edited by

Stefano Marletta

and

Giuseppe Fanelli

submission deadline 30 Jun 2026 | Viewed by 104 | Submission Open

Keywords: prostate cancer; Gleason grading; molecular pathology; artificial intelligence; digital pathology; multimodal algorithms

(This special issue belongs to the Section Cancer Pathophysiology)

Molecular Mechanisms of Cancer Progression and Metastasis

edited by

Babak Behnam

submission deadline 30 Jun 2026 | Viewed by 97 | Submission Open

Keywords: metastasis; molecular mechanisms; tumor microenvironment (TME); epithelial-to-mesenchymal transition (EMT); cancer stem cell; therapeutic strategies; immune evasion

(This special issue belongs to the Section Cancer Metastasis)

CDK4/6 Inhibitors in Cancer: Efficacy, Resistance, and Combination Approaches

edited by

Boshi Wang

submission deadline 30 Jun 2026 | Viewed by 95 | Submission Open

Keywords: CDK4/6 inhibitors; palbociclib; abemaciclib; ribociclib; cancer; senescence; combinatorial therapy; prognosis; molecular mechanisms

(This special issue belongs to the Section Cancer Therapy)

Tumor Heterogeneity in Breast Cancer—the “Omics” Revolution

edited by

Angeliki Magklara

and

Spyros Foutadakis

submission deadline 30 Jun 2026 | Viewed by 94 | Submission Open

Keywords: breast cancer; tumor heterogeneity; tumor microenvironment; transcriptional regulation; single-cell RNA-seq; spatial transcriptomics; genomics; epigenomics; proteomics; metabolomics

(This special issue belongs to the Section Molecular Cancer Biology)

Ras-Directed Therapies: A Revolution

edited by

Naiara Perurena

submission deadline 30 Jun 2026 | Viewed by 86 | Submission Open

Keywords: Ras-driven cancers; Ras inhibitors; Ras degraders; Ras signaling; mechanisms of resistance; combination therapies

(This special issue belongs to the Section Cancer Therapy)

Radiation Therapy for Metastatic Cancer

edited by Johnny Kao

submission deadline 30 Jun 2026 | Viewed by 85 | Submission Open

Keywords: metastasis; radiation therapy; tumor agnostic; oligometastases; survivorship; combined modality therapy

(This special issue belongs to the Section Cancer Therapy)

Progress in Targeted Nanotherapeutic Delivery Systems for Cancer Precision Medicine

edited by

Linlin Zhang

and Dhananjay Suresh

submission deadline 30 Jun 2026 | Viewed by 78 | Submission Open

Keywords: cancer therapy; drug delivery; tumor targeting; nanotechnology; precision medicine; immunotherapy; new approach methodologies (NAMs)

(This special issue belongs to the Section Methods and Technologies Development)

Magnetic Resonance in Cancer Research (2nd Edition)

edited by Qiuhong He and Marie-France Vidaver

submission deadline 30 Jun 2026 | Viewed by 76 | Submission Open

Keywords: magnetic resonance; cancer; MRI; MRS; MRSI; NMR; DWI; MR; molecular imaging

(This special issue belongs to the Section Methods and Technologies Development)

Emerging Opportunities in Radiation Oncology: AI, Radiomics, and Particle Therapy Breakthroughs

edited by

Antonio Pontoriero

and

Sara Lillo

submission deadline 30 Jun 2026 | Viewed by 71 | Submission Open

Keywords: radiotherapy; artificial intelligence; radiomics; machine learning; adaptive planning; proton therapy; hadron therapy; precision oncology; particle radiotherapy; clinical outcomes

Immunotherapy for Acute Lymphoblastic Leukemia: Novel Strategies and Clinical Perspectives

edited by Paola Minetto and

Francesco Grimaldi

submission deadline 30 Jun 2026 | Viewed by 70 | Submission Open

Keywords: immunotherapy; CAR T-cell therapy; bispecific antibodies; antibody– drug conjugates; treatment resistance; clinical perspectives; clinical trial in ALL

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Symptom Burden in Cancer: Assessment and Management: 2nd Edition

edited by Sam M. Salek,

Esther Natalie Oliva

and Tatyana Ionova

submission deadline 30 Jun 2026 | Viewed by 69 | Submission Open

Keywords: symptom burden; patient-reported outcomes; symptom assessment; symptom management; cancer survivorship; quality of life

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Fertility and Pregnancy in Cancer

edited by

Bettina Böttcher

submission deadline 30 Jun 2026 | Viewed by 61 | Submission Open

Keywords: cancer; gonadotoxic treatment; pregnancy; offspring; long term survivorship; fertility preservation

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

Living with Cancer as a Chronic Disease: Quality of Life and Supportive Care

edited by

Paolo Cotogni

submission deadline 30 Jun 2026 | Viewed by 48 | Submission Open

Keywords: long-term symptom management; palliative care; awareness; coping strategies; survivorship; caregiver; multidisciplinary care coordination

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Molecular Insights into Drug Resistance in Cancer: 2nd Edition

edited by Yuqi Yang

submission deadline 30 Jun 2026 | Viewed by 36 | Submission Open

Keywords: drug resistance; cancer treatment; molecular mechanism; chemotherapeutic therapy; small molecules; biologics/large molecules; leukemia; solid tumor

Autophagy and Apoptosis in Cancer Progression

edited by Antonio Ieni

submission deadline 30 Jun 2026 | Viewed by 30 | Submission Open

Keywords: autophagy; apoptosis; cancer progression; cell death pathways; therapeutic resistance

(This special issue belongs to the Section Molecular Cancer Biology)

Breast Cancer Evolution—Insights from Single-Cell Genomics

edited by

Cynthia Ma

submission deadline 30 Jun 2026 | Viewed by 30 | Submission Open

Keywords: single-cell genomics; tumor evolution; intratumoral heterogeneity; lineage plasticity; therapy resistance; spatial transcriptomics; tumor microenvironment; clonal dynamics; multi-omics profiling

(This special issue belongs to the Section Molecular Cancer Biology)

Diagnostic and Pathological Markers in Human Cancer

edited by

Zuoren Yu

Shengqiong Deng

and Qian Zhao

submission deadline 30 Jun 2026 | Viewed by 29 | Submission Open

Keywords: cancer; biomarker; early diagnosis; pathological markers; prognostic model

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Advances in Treatment of Bladder Cancer

edited by

Murat Akand

and

Guglielmo Mantica

submission deadline 30 Jun 2026 | Viewed by 28 | Submission Open

Keywords: bladder cancer; diagnostic biomarkers; genomics; therapeutic approaches

(This special issue belongs to the Section Cancer Therapy)

Advances and Challenges in Head and Neck Cancer

edited by

Marc Oliva

, Leonor Abreu Ribeiro and Claúdia Vieira

submission deadline 30 Jun 2026 | Viewed by 26 | Submission Open

Keywords: head and neck cancer; biomarkers; immunotherapy; radiosensitizers; multiple tumors

Advances in Dermoscopy for Melanoma and Non-Melanoma Skin Cancer

edited by

Clay J. Cockerell

, Warren Chan, Jade Conway and

Iman Ali

submission deadline 30 Jun 2026 | Viewed by 24 | Submission Open

Keywords: dermoscopy; skin cancer; diagnosis; artificial intelligence; multimodal imaging; teledermoscopy

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

New Implication in the Platelet–Cancer Interplay

edited by Lenard M. Lichtenberger

submission deadline 30 Jun 2026 | Viewed by 24 | Submission Open

Keywords: platelet; COX-1; aspirin; phosphatidylcholine; colorectal cancer; thrombocytosis

Digital Pathology and AI for Tumor Microenvironment Mapping

edited by Mohammadreza Azimi

submission deadline 30 Jun 2026 | Viewed by 24 | Submission Open

Keywords: tumor microenvironment; digital pathology; artificial intelligence; spatial analysis; computational histopathology; deep learning; cancer prognostics; machine learning; image-based biomarkers; federated learning

Cellular Immunotherapy for Leukemias—Advances, Limitations, and the Path Forward

edited by Lohith Gowda and Stuart E. Seropian

submission deadline 30 Jun 2026 | Viewed by 22 | Submission Open

Keywords: cellular therapy; cellular immunotherapy; leukemias

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Tumor Immune Microenvironment: Molecular Mechanism and Signaling Pathway

edited by Hua Tian

submission deadline 30 Jun 2026 | Viewed by 19 | Submission Open

Keywords: tumor immune microenvironment; signaling pathways; immunotherapy; crosstalk

Tumor Microenvironment (TME): Cellular and Molecular Interactions

edited by

Mauricio Retamal

submission deadline 30 Jun 2026 | Viewed by 18 | Submission Open

Keywords: cancer stem cells; hypoxia; connexins; tumor microenvironment; extracellular ATP; immune cells; extracellular acidification; extracellular matrix; extracellular vesicles

(This special issue belongs to the Section Tumor Microenvironment)

Actual Aspects of Prostate Cancer Treatment—an Interdisciplinary Approach (Third Edition)

edited by

Hans Christiansen

submission deadline 30 Jun 2026 | Viewed by 16 | Submission Open

Keywords: prostate cancer; surgery; radiotherapy; hypofractionation; interdisciplinarity; nuclear medicine; PSMA

(This special issue belongs to the Section Cancer Therapy)

Novel Insights into Mechanisms of Cancer-Associated Thrombosis: 2nd Edition

edited by Tom A J Mckinnon

submission deadline 30 Jun 2026 | Viewed by 14 | Submission Open

Keywords: cancer; thrombosis; venous; arterial

(This special issue belongs to the Section Molecular Cancer Biology)

The Use of Artificial Intelligence in Predicting Response to Cancer Therapy

edited by

Arturo Loaiza-Bonilla

submission deadline 30 Jun 2026 | Viewed by 12 | Submission Open

Keywords: artificial intelligence; response prediction; precision oncology; machine learning; multimodal data integration; immunotherapy biomarkers; treatment resistance; clinical decision support; real-world data; explainable AI

Calcium-Linked Messaging in Cancer

edited by

Amantini Consuelo

submission deadline 30 Jun 2026 | Viewed by 9 | Submission Open

Keywords: interorganellar Ca2+ communication; membrane contact sites; tumor progression; intracellular Ca2+ flux; cation channels; calcium dysregulation; cell fate; targeted therapy

(This special issue belongs to the Section Tumor Microenvironment)

Psychosocial Health and Quality of Life Across the Cancer Care Continuum

edited by

Qin Xiang Ng

and Serene Si Ning Goh

submission deadline 30 Jun 2026 | Viewed by 8 | Submission Open

Keywords: cancer survivorship; psychological outcomes; quality of life; health-related quality of life; patient-reported outcomes; fear of recurrence; cancer-related fatigue; mental health; body image; supportive care

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Reappearance of Dawn: CAR-T Restricts Glioblastoma

edited by

Qianxue Chen

submission deadline 30 Jun 2026 | Viewed by 8 | Submission Open

Keywords: CAR-T cell therapy; glioblastoma (GBM); immunotherapy; antigen escape; blood– brain barrier; immunosuppressive tumor microenvironment; clinical efficacy; toxicity; combination therapy; future strategies

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Cancer-Associated Thrombosis, Arterial and Venous Thromboembolism

edited by

Omer Iqbal

submission deadline 30 Jun 2026 | Viewed by 5 | Submission Open

Keywords: cancer; deep vein thrombosis; pulmonary embolism; venous thromboembolism; anticoagulants; cardio-oncology; artificial intelligence; machine learning

(This special issue belongs to the Section Cancer Pathophysiology)

Clinical Studies in Gastrointestinal Malignancies: 2nd Edition

edited by

Ulrich Ronellenfitsch

submission deadline 30 Jun 2026 | Viewed by 3 | Submission Open

Keywords: gastrointestinal cancers; clinical studies; multimodal treatment; study design; outcomes

(This special issue belongs to the Section Clinical Research of Cancer)

Integrating Neoadjuvant Immunotherapy and Surgery for NSCLC: From Biomarkers to Optimized Resection Tactics

edited by Piergiorgio Solli and

Giovanni Leuzzi

submission deadline 30 Jun 2026 | Viewed by 1 | Submission Open

Keywords: neoadjuvant immunotherapy; NSCLC; precision surgery; pathological response (pCR/MPR); ctDNA; sublobar resection; fibrosis; multidisciplinary team

(This special issue belongs to the Section Cancer Therapy)

Advances in Therapeutic Strategies for Prostate Cancer

edited by Angelo Naselli and

Giacomo Maria Pirola

submission deadline 1 Jul 2026 | 5 articles | Viewed by 22664 | Submission Open

Keywords: immunotherapy; radiation therapy; hormone therapy; targeted therapies

(This special issue belongs to the Section Cancer Therapy)

Pediatric Brain Tumors: Symptoms, Diagnosis and Treatments

edited by Christian Ott and Julius Höhne

submission deadline 1 Jul 2026 | 3 articles | Viewed by 8372 | Submission Open

Keywords: MRI/CT scans; radiation therapy; chemotherapy; combined therapy

(This special issue belongs to the Section Cancer Therapy)

The Role of Radiotherapy, Immunotherapy and New Surgical Techniques in the Treatment of Lung Neoplasms

edited by

Elisa Meacci

submission deadline 1 Jul 2026 | 3 articles | Viewed by 7603 | Submission Open

Keywords: radiotherapy; immunotherapy; new surgical techniques; lung cancer

(This special issue belongs to the Section Cancer Therapy)

The Mediastinum—Pandora’s Box

edited by

Cesar A. Moran

submission deadline 1 Jul 2026 | Viewed by 560 | Submission Open

Keywords: mediastinum; thymus; imaging; surgery; thymoma; germ cell tumors

Clinical Trials for Diffuse Large B-Cell Lymphomas (DLBCL)

edited by

Erel Joffe

submission deadline 1 Jul 2026 | Viewed by 337 | Submission Open

Keywords: DLBCL; immunotherapy; drug combinations; elderly patients; ctDNA; biomarkers; radiotherapy; clinical trial management; artificial intelligence

(This special issue belongs to the Section Clinical Research of Cancer)

Advancing CAR-T Cell Therapy: The Next Evolution in Breast Cancer Treatment

edited by

Nethaji Muniraj

and

Arun Dharmarajan

submission deadline 1 Jul 2026 | Viewed by 200 | Submission Open

Keywords: CAR-T cell therapy; breast cancer; triple-negative breast cancer (TNBC); HER2-positive breast cancer; tumor microenvironment; immunotherapy

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

The Role of Opioid Therapy for Cancers

edited by Brian Le and

Aaron K. Wong

submission deadline 1 Jul 2026 | Viewed by 54 | Submission Open

Keywords: opioids; palliative care; chronic cancer pain

(This special issue belongs to the Section Cancer Therapy)

Metals in Cancer: From Molecular Mechanisms to Innovative Therapeutics

edited by

Katarina Zivancevic

submission deadline 5 Jul 2026 | Viewed by 81 | Submission Open

Keywords: essential and toxic metals; metal-induced carcinogenesis; metal homeostasis; metallotherapeutics; oxidative stress; tumor microenvironment; immune modulation; metabolic reprogramming; therapy resistance; drug delivery systems

(This special issue belongs to the Section Molecular Cancer Biology)

Microfluidic Technology in Cancer

edited by

Lanju Mei

and

Diganta Dutta

submission deadline 5 Jul 2026 | Viewed by 70 | Submission Open

Keywords: cancer cells separation; cancer cells isolation; cancer cells treatment; lab-on-a-chip technology; bio microfluidics; biomedical microdevices; biosensors; and detection in microfluidics

(This special issue belongs to the Section Methods and Technologies Development)

Perioperative Management and Cancer Outcomes (2nd Edition)

edited by

Daniela Ionescu

submission deadline 9 Jul 2026 | Viewed by 139 | Submission Open

Keywords: perioperative management; cancer treatment outcomes; onco-anesthesiology; preoperative risk assessment; enhanced recovery after surgery (ERAS); pain management; personalized medicine

(This special issue belongs to the Section Cancer Therapy)

Upper Tract Urothelial Carcinoma: Current Knowledge and Perspectives

edited by Katie S. Murray and Saum Ghodoussipour

submission deadline 10 Jul 2026 | 3 articles | Viewed by 8113 | Submission Open

Keywords: upper tract urothelial carcinoma; upper tract disease; urothelial cell carcinoma

(This special issue belongs to the Section Cancer Therapy)

Neuroendocrine Neoplasms: Pathogenesis, Diagnostics, and Therapy

edited by

Beata Jabłońska

submission deadline 10 Jul 2026 | 1 articles | Viewed by 6660 | Submission Open

Keywords: neuroendocrine neoplasms; pathogenesis; diagnostics; therapy

(This special issue belongs to the Section Cancer Therapy)

Clinicopathological Study of Gynecologic Cancer (2nd Edition)

edited by

Massimo Origoni

submission deadline 10 Jul 2026 | 1 articles | Viewed by 1237 | Submission Open

Keywords: gynecological oncology; gynecological cancer; female cancer; uterine cancer; ovarian cancer; endometrial cancer; cancerogenesis; cancer biology; cell transformation; cancer pathology; cancer biology

(This special issue belongs to the Section Clinical Research of Cancer)

Beyond Cancer: Enhancing Quality of Life for Cancer Survivors (Second Edition)

edited by

Jennifer Jones

, Maryam Lustberg and Muna Al-Khaifi

submission deadline 10 Jul 2026 | Viewed by 88 | Submission Open

Keywords: psychosocial oncology; cancer survivorship; long-term effects of cancer; psychoeducational interventions; nnovative care models; continuing education; knowledge translation

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Preoperative Optimisation in Patients Undergoing Cancer Surgery: 2nd Edition

edited by

Daniel Steffens

and

Cherry Koh

submission deadline 10 Jul 2026 | Viewed by 85 | Submission Open

Keywords: prehabilitation; medical optimization; exercise; nutrition; psychological interventions; surgery; cancer; surgical outcome; preoperative; clinical trials

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Displaying special issue 851-900 on page 18 of 25.

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