Submit to Biomolecules Review for Biomolecules Propose a Special Issue

Journal Menu

Journal Browser

Special Issues

Biomolecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

Section

Search by Title/Keyword

Order results

Display

Results per page

Oral Cancer: New Advances in Therapies

edited by

Daniela Adamo

Gennaro Musella

and Nicola Cirillo

submission deadline 20 Jun 2026 | Viewed by 35 | Submission Open

Keywords: oral cancer; targeted therapy; immunotherapy; biomarkers; tumor microenvironment; radiotherapy; chemotherapy; gene therapy; precision medicine; translational research

(This special issue belongs to the Section Molecular Medicine)

South American Native Species as Sources of Bioactive Compounds: Opportunities and Challenges

edited by Andressa Mara Baseggio and Maurício Ariel Rostagno

submission deadline 20 Jun 2026 | Viewed by 33 | Submission Open

Keywords: South American biodiversity; bioactive compounds; chemical characterization; health properties

(This special issue belongs to the Section Natural and Bio-derived Molecules)

Pulmonary Fibrosis: From Molecular Mechanism to Therapeutic Targets

edited by Santosh Yadav, Muralidharan Anbalagan and Renat Shaykhiev

submission deadline 25 Jun 2026 | Viewed by 25 | Submission Open

Keywords: idiopathic pulmonary fibrosis; DNA damage response; senescence; immune checkpoint inhibitors

(This special issue belongs to the Section Molecular Medicine)

Spotlight on Hot Cancer Biological Biomarkers

edited by

Dania Cioni

and

Salvatore Claudio Fanni

submission deadline 30 Jun 2026 | 4 articles | Viewed by 6395 | Submission Open

Keywords: cancer biomarkers; precision medicine; liquid biopsy; imaging biomarkers; translational oncology

(This special issue belongs to the Section Molecular Biomarkers)

Mechanisms of Kidney Injury and Treatment Modalities

edited by Utpal Sen

submission deadline 30 Jun 2026 | 2 articles | Viewed by 5221 | Submission Open

Keywords: acute and chronic kidney injury; autophagy and mitophagy; bioenergetics; mitochondrial damage; and biogenesis; current therapeutic modalities and future strategies; epigenetic DNA methylation; histone modification; and non-coding RNAs and miRNAs; gaseous molecules and signaling pathways; gender differences; aging; and kidney dysfunction; glomerulosclerosis and renovascular remodelling following injury; gut– kidney axis and health; hypertensive; diabetic; and IgA nephropathy; inflammatory vs. reparatory macrophages and renal repair; ischemia and reperfusion injury; matrix protein; metalloproteinases; and their inhibitors; necrosis; necroptosis; apoptosis; pyroptosis; and ferroptosis; renal repair and regeneration

(This special issue belongs to the Section Molecular Biology)

New Insights into Protein Aggregation in Condensed and Amyloid States

edited by

Eva Žerovnik

and

Veronika Stoka

submission deadline 30 Jun 2026 | 2 articles | Viewed by 3384 | Submission Open

Keywords: proteinopathies; protein aggregation; physico-chemical and biological properties of amyloid fibrils and protein condensates; signal and light transduction; interaction with lipid membranes; aggregating protein interactomes; bioinformatics and machine learning; molecular dynamics

(This special issue belongs to the Section Biomacromolecules: Proteins, Nucleic Acids and Carbohydrates)

Advances in Pharmacognosy and Phytochemistry: From Molecular to Pre-Clinical Insights

edited by

Hilal Zaid

Zipora Tietel

and

Akhilesh K. Tamrakar

submission deadline 30 Jun 2026 | 1 articles | Viewed by 2462 | Submission Open

Keywords: metabolomics; drug discovery; phytopharmacology; medicinal plants

(This special issue belongs to the Section Natural and Bio-derived Molecules)

Molecular Basis and Novel Treatment of Epilepsy

edited by

Fang Zheng

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1930 | Submission Open

Keywords: epilepsy; genetic basis; epileptogenesis; antiseizure drugs; novel treatment; translational research

(This special issue belongs to the Section Molecular Biology)

Molecular Pathology, Diagnostics, and Therapeutics of Lung Disease

edited by

Toshimitsu Yamaoka

submission deadline 30 Jun 2026 | 2 articles | Viewed by 1562 | Submission Open

Keywords: pulmonary diseases; diagnostics; therapeutics

(This special issue belongs to the Section Molecular Medicine)

Mitochondria as a Target for Tissue Repair and Regeneration

edited by

Igor A. Prudovsky

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1038 | Submission Open

Keywords: mitochondria; trauma; tissue repair; regeneration; inflammation; mitochondrial DAMPs; mitochondrial biogenesis; mitophagy

(This special issue belongs to the Section Molecular Biology)

Soft Matter and Self-Assembly: From Biomaterials to Nanomaterials

edited by Caterina Ricci and

Maria Grazia Ortore

submission deadline 30 Jun 2026 | Viewed by 207 | Submission Open

Keywords: soft matter; self-assembly; biomaterials; nanomaterials; bioinspired materials; drug delivery; responsive materials; tissue engineering; nanotechnology; molecular organization

Unraveling the Mysteries of Muscle: Advances in Myogenesis, Physiology, and Wasting Disorders

edited by

Wan Lee

submission deadline 30 Jun 2026 | Viewed by 188 | Submission Open

Keywords: muscle biology; molecular mechanism; myogenesis; muscle physiology; muscle wasting; sarcopenia; cachexia; muscle-related pathologies

Recent Advances in Cellular and Molecular Mechanisms of Cardiovascular and Metabolic Diseases: 3rd Edition

edited by

Adriana Georgescu

submission deadline 30 Jun 2026 | Viewed by 103 | Submission Open

Keywords: cardiovascular disease; dyslipidemia; diabetes; obesity; inflammation; oxidative stress; biomarkers; microRNA; extracellular vesicles; cardiopulmonary disease

Exercise Immunology: Molecular Mechanisms and Health Applications

edited by

Dorota Kostrzewa-Nowak

Robert Nowak

, Michał Sławiński and

Patrizia Proia

submission deadline 30 Jun 2026 | Viewed by 88 | Submission Open

Keywords: post-effort immune response; lifestyle-associated molecular patterns; damage-associated molecular patterns; immune cell; cell signaling; cell death; growth factor; chemokines; cytokines; transcription factors

(This special issue belongs to the Section Molecular Biology)

Molecular and Physiological Regulation of Biomechanical Signalling

edited by

Lars Kaestner

submission deadline 30 Jun 2026 | Viewed by 70 | Submission Open

Keywords: biomechanics; molecular signalling; mechanosensitive ion channels; Piezo1& 2; microfluidics

Role of Mesenchymal Stem/Stromal Cells and Their Extracellular Vesicles in the Regenerative Medicine of Musculoskeletal System

edited by

Dimitrios Kouroupis

and

Enrico Ragni

submission deadline 30 Jun 2026 | Viewed by 58 | Submission Open

Keywords: mesenchymal stem/stromal cells; extracellular vesicles ; musculoskeletal regeneration ; immunomodulation ; anabolism ; cell therapy ; cell-free therapy ; secretome

Novel Insights into Epithelial Mesenchymal Transition (EMT) in Cancer

edited by

Shuya Yano

submission deadline 30 Jun 2026 | Viewed by 48 | Submission Open

Keywords: EMT; epithelial– mesenchymal plasticity; hybrid E/M states; single-cell; spatial transcriptomics/proteomics; multiplex IHC/IF; RNA in situ; CTCs; ctDNA; radiomics; computational pathology; immune evasion; therapy resistance; metastasis; biomarkers; reporting standards; reproducibility; clinical translation

(This special issue belongs to the Section Molecular Medicine)

Novel Biomarkers in Breast Cancer: Leveraging Multi-Omics and AI for Discovery and Validation

edited by Konstantinos Venetis,

Nicola Fusco

and Marianna D'Ercole

submission deadline 30 Jun 2026 | Viewed by 48 | Submission Open

Keywords: breast cancer; biomarkers; liquid biopsy; multi-omics; digital pathology

(This special issue belongs to the Section Molecular Biomarkers)

Enolase: Molecular Functions and Pathological Roles in Health and Disease

edited by

Anja Pišlar

submission deadline 30 Jun 2026 | Viewed by 46 | Submission Open

Keywords: enolase; enzyme regulation; cancer metabolism; neurodegeneration; autoimmune disease; biomarkers; inflammation; therapeutic targets

(This special issue belongs to the Section Cellular Biochemistry)

Forces Driving Macromolecular Recognition: Role in Drug Design and Discovery

edited by David P. Remeta and

Conceição A. Minetti

submission deadline 30 Jun 2026 | Viewed by 42 | Submission Open

Keywords: macromolecular recognition; drug design and discovery; biomolecular structure and dynamics; computational modeling; ligand– receptor binding energetics; drug-target interactions; thermodynamic forces; protein-ligand binding; drug discovery and optimization; protein-nucleic acid interactions; intrinsically disordered proteins; protein aggregation and disease

(This special issue belongs to the Section Chemical Biology)

Multifunctional Nanocarriers for Advanced Therapy and Diagnosis

edited by

Buddhadev Layek

submission deadline 30 Jun 2026 | Viewed by 16 | Submission Open

Keywords: nanocarriers; targeted drug delivery; stimuli-responsive nanoparticles; biological barriers; smart delivery systems; nanotheranostics; functionalized nanoparticles

(This special issue belongs to the Section Bio-Engineered Materials)

Advances in Protein–Ligand Interactions: From Structure, Function to Applications, 2nd Edition

edited by

Mateusz Banach

submission deadline 30 Jun 2026 | Viewed by 11 | Submission Open

Keywords: bioinformatics; compound libraries; computational biology; de novo drug design; drug discovery; ligand binding; machine learning; molecular docking; molecular dynamics; protein complexes

(This special issue belongs to the Section Chemical Biology)

Plant Secondary Metabolism Engineering and Bioactive Compounds

edited by

Barbara Tokarz

and

Wojciech Makowski

submission deadline 30 Jun 2026 | Viewed by 10 | Submission Open

Keywords: bioactive compounds; elicitation; plant metabolism; fenetic transformation

(This special issue belongs to the Section Natural and Bio-derived Molecules)

Molecular Mechanism of Viral Infection and Host Immunity in Transplantation

edited by Eva Mischak Weissinger

submission deadline 30 Jun 2026 | Viewed by 1 | Submission Open

Keywords: allogeneic stem cell/or solid organ transplantation; immunosuppressed host; immune reconstitution; virus reactive/specific cytotoxic T-/NK-cells; immune reconstitution post-transplantation

(This special issue belongs to the Section Molecular Medicine)

Regulation of Synapses in the Brain

edited by

Kunwei Wu

and Guohao Wang

submission deadline 17 Jul 2026 | 1 articles | Viewed by 929 | Submission Open

Keywords: synaptic plasticity; neurodevelopmental disorders; glial cells; synaptic formation; learning and memory; neuroinflammation; neurodegenerative diseases; extracellular matrix; synaptic dysfunction; therapeutic interventions

(This special issue belongs to the Section Molecular Biology)

Computational Analysis and Conformational Modeling for Protein Structure and Interaction: Second Edition

edited by

Clement Agoni

and

Indrani Bera

submission deadline 24 Jul 2026 | Viewed by 21 | Submission Open

Keywords: protein structure prediction; drug discovery targeting proteins; structural bioinformatics; molecular dynamics simulations; protein– protein interactions; protein– ligand binding; conformational dynamics; molecular docking studies

(This special issue belongs to the Section Biomacromolecules: Proteins, Nucleic Acids and Carbohydrates)

The Role of Mechanotransduction in Cellular Biology

edited by

Frederick H. Silver

submission deadline 31 Jul 2026 | 3 articles | Viewed by 9146 | Submission Open

Keywords: cell membrane; cytosol; nuclear membrane; integrin; mechanotransduction; map kinase pathway; ERKs; JNKs; p38/SAPKs; YAP/TAZ; Hippo pathway

(This special issue belongs to the Section Cellular Biochemistry)

Molecular Mechanisms of Skeletal Muscle Growth and Loss in Health, Aging, and Disease

edited by

Khaled Kamal

submission deadline 31 Jul 2026 | Viewed by 227 | Submission Open

Keywords: skeletal muscle; muscle growth and atrophy; metabolic signaling (anabolic/catabolic); mechanotransduction; redox biology and oxidative stress; inflammation and immune signaling; obesity and metabolic disease; sarcopenia and aging; cachexia and neuromuscular disease; extracellular vesicles and exosomes

(This special issue belongs to the Section Molecular Biology)

Therapeutics Targeting Pathogenic Mechanisms of Leishmaniasis

edited by

Kwang Poo Chang

submission deadline 31 Jul 2026 | Viewed by 141 | Submission Open

Keywords: leishmaniasis; host– parasite interactions; pathogenicity; precision medicine; AI-assisted development of therapeutics

Redox Dysregulation and Mitochondrial Adaptation in Kidney Disease

edited by

Liang-Jun Yan

submission deadline 31 Jul 2026 | Viewed by 136 | Submission Open

Keywords: acute kidney injury; chronic kidney disease; diabetic nephropathy; diabetic kidney disease; redox imbalance; reductive stress; reactive oxygen species; oxidative stress; mitochondrial stress response and adaptation; mitochondrial abnormalities; mitochondrial homeostasis; mitophagy; unfolded protein response

Design and Applications of 3D Bioprinting

edited by

Saman Naghieh

and

Chaozong Liu

submission deadline 31 Jul 2026 | Viewed by 95 | Submission Open

Keywords: 3D bioprinting; biofabrication; tissue engineering; regenerative medicine; smart biomaterials; scaffold design; organ models; personalized therapeutics; biomedical additive manufacturing; translational bioprinting

(This special issue belongs to the Section Bio-Engineered Materials)

Heterocyclic Compounds: Synthesis, Characterization, and Validation

edited by

Monika Pitucha

submission deadline 31 Jul 2026 | Viewed by 93 | Submission Open

Keywords: heterocyclic compounds; synthesis; spectroscopy; molecular modeling; biological activity; radiopharmaceuticals

(This special issue belongs to the Section Chemical Biology)

Hepatic Stellate Cells and Immune Microenvironment in Hepatocellular Carcinoma

edited by

Tai-long Pan

submission deadline 31 Jul 2026 | Viewed by 45 | Submission Open

Keywords: hepatic stellate cell; hepatocellular carcinoma; immune microenvironment; extracellular matrix; epigenetics; tumor microenvironment; inflammation

(This special issue belongs to the Section Molecular Medicine)

Mutagenesis and Genetic Instability in Genome Evolution and in Cancer: Mechanisms, Consequences, and Therapeutic Perspectives

edited by

Said Aoufouchi

and Rabii Ameziane El Hassani

submission deadline 31 Jul 2026 | Viewed by 40 | Submission Open

Keywords: genomic instability; mutagenesis; evolution; genetic diversification DNA repair; epigenetic; cancers; therapy resistance

(This special issue belongs to the Section Molecular Biology)

Applications of Biomaterials in Medicine and Healthcare

edited by

Patrícia Alves

and

Paula Ferreira

submission deadline 31 Aug 2026 | 2 articles | Viewed by 5677 | Submission Open

Keywords: biomaterials; tissue engineering; biomedical applications; drug delivery systems; medical implants

Iron Metabolism in Cells

edited by

Magdalena Gryzik

and

Michela Asperti

submission deadline 31 Aug 2026 | Viewed by 884 | Submission Open

Keywords: iron metabolism; iron-related proteins; iron uptake; iron storage; mitochondrial iron metabolism; iron sensing mechanism; ferroptosis

(This special issue belongs to the Section Cellular Biochemistry)

The Role of Extracellular Non-Coding RNAs in Health and Disease

edited by

Arijit Mukhopadhyay

submission deadline 31 Aug 2026 | Viewed by 72 | Submission Open

Keywords: extracellular vesicles; exosomes; non-coding RNA; microRNA; biomarker

(This special issue belongs to the Section Molecular Biomarkers)

Nanomaterials and Iron Proteins: Molecular Interactions, Structural Characterization, and Biomedical Applications

edited by

Georgia C. Papaefthymiou

submission deadline 31 Aug 2026 | Viewed by 19 | Submission Open

Keywords: iron storage (ferritin); iron transport (transferrin; ferroportin); O2 storage (myoglobin); O2 transport (hemoglobin); electron transfer (Fe-S proteins; cytochromes); ferritin degradation; (ferritinophagy); oxidative stress protection (ferritin; Dps proteins); biocompatible iron-oxide nanoparticles; magnetoferritin; biogenic magnetite by magnetotactic bacteria (magnetosomes); iron-based metal– organic frameworks (Fe-MOFs)

(This special issue belongs to the Section Molecular Biology)

State-of-the-Art of Myology: 3rd Edition

edited by

Guglielmo Sorci

and

Francesca Riuzzi

submission deadline 31 Aug 2026 | Viewed by 1 | Submission Open

Keywords: embryonic myogenesis; adult myogenesis; exercise-induced muscle injury; muscular dystrophies and muscle diseases; sarcopenia; cachexia; rhabdomyosarcoma; muscle biophysics

(This special issue belongs to the Section Molecular Biology)

Molecular Mechanisms and Microenvironmental Regulation in Bone-Related Diseases and Muscle Atrophy

edited by Haitao Wang

submission deadline 1 Sep 2026 | Viewed by 66 | Submission Open

Keywords: bone diseases; muscle atrophy; osteoporosis; osteoarthritis; osteosarcoma; sarcopenia; heterotopic ossification; molecular mechanisms; microenvironment; therapeutic targets

(This special issue belongs to the Section Molecular Medicine)

Role of Lipids in Cellular Metabolism and Communication

edited by

Leyre Brizuela

submission deadline 30 Sep 2026 | Viewed by 81 | Submission Open

Keywords: sphingolipids; phospholipids; eicosanoids; steroids; extracellular vesicles; cancer; diabetes; obesity; atherosclerosis

(This special issue belongs to the Section Lipids)

Advances in Targeted At-211 Alpha Therapy

edited by Hsiaoju Sharon Lee and Yawen Li

submission deadline 30 Sep 2026 | Viewed by 51 | Submission Open

Keywords: Astatine-211; astatination; targeted alpha therapy; alpha radioimmunotherapy; radiotheranostics; radiopharmaceuticals

(This special issue belongs to the Section Chemical Biology)

The Impact of Blood Pressure on Neurological Outcomes

edited by Phillip J. Tully

submission deadline 30 Sep 2026 | Viewed by 13 | Submission Open

Keywords: neurological disorders; neurodegenerative disorders; brain imaging; dementia; hypertension; blood pressure; cerebral blood flow

(This special issue belongs to the Section Molecular Medicine)

The Function of Stromal Cells in Gastrointestinal (GI) Diseases

edited by Li Chang

submission deadline 23 Oct 2026 | Viewed by 6 | Submission Open

Keywords: gastrointestinal (GI) diseases; intestinal stromal cells; intestinal homeostasis; cytokine; extracellular matrix; tissue repair

(This special issue belongs to the Section Molecular Medicine)

Computational Pharmacology: Advances in Computational Modeling of Drug–Receptor Interactions and Pharmacokinetics

edited by

Clement Agoni

and

Indrani Bera

submission deadline 30 Oct 2026 | Viewed by 29 | Submission Open

Keywords: computational pharmacology; drug– receptor interactions; pharmacokinetics modeling; molecular dynamics simulations; molecular docking; QSAR analysis; ADME prediction; AI in drug design; machine learning for drug discovery; protein– ligand binding; bioactive peptide– protein interactions; drug– enzyme interactions; drug– nucleic acid interactions; protein– lipid interactions; peptoid-target interactions; therapeutic optimization; pharmacodynamic modeling

(This special issue belongs to the Section Biomacromolecules: Proteins, Nucleic Acids and Carbohydrates)

Novel Molecular Targets for Beta Cell Regeneration and Diabetes Therapy

edited by Iraj Alipourfard

submission deadline 30 Oct 2026 | Viewed by 14 | Submission Open

Keywords: diabetes; pancreatic beta cells; regenerative therapy; molecular target

(This special issue belongs to the Section Molecular Medicine)

Recent Molecular Research on Protein Structure and Function

edited by

Sonani Ravi Raghav

submission deadline 15 Dec 2026 | Viewed by 557 | Submission Open

Keywords: protein structure; protein function; molecular mechanisms; protein folding; structural biology

(This special issue belongs to the Section Molecular Biology)

Advances in Galectins

edited by Anu Paul and Diyoly Ayona

submission deadline 31 Dec 2026 | 2 articles | Viewed by 5296 | Submission Open

Keywords: galectins; carbohydrate-binding proteins; galectin– microbe

(This special issue belongs to the Section Biomacromolecules: Proteins, Nucleic Acids and Carbohydrates)

Molecular Insights into Quantum Biology

edited by Daniel R. Kattnig

submission deadline 31 Dec 2026 | Viewed by 62 | Submission Open

Keywords: quantum biology; molecular mechanisms; quantum coherence; quantum entanglement; magnetoreception; quantum cognition; photosynthetic energy transfer; biological qubits; quantum sensing; environment-assisted quantum effects

(This special issue belongs to the Section Molecular Biophysics: Structure, Dynamics, and Function)

Human ABC Transporters in Drug Disposition and Resistance: 50 Years of Progress and Future Perspectives

edited by

Hiroshi Nakagawa

submission deadline 31 Dec 2026 | Viewed by 45 | Submission Open

Keywords: ABC transporters; drug disposition; drug resistance; pharmacokinetics; pharmacodynamics; pharmacogenetics; single nucleotide polymorphisms (SNPs)

(This special issue belongs to the Section Chemical Biology)

Displaying special issue 451-500 on page 10 of 11.

Go to page 8 9 10 11

Journal Menu

Journal Browser

Special Issues

Further Information

Guidelines

MDPI Initiatives

Follow MDPI