Regulation of Synapses in the Brain
A special issue of Biomolecules (ISSN 2218-273X).
Deadline for manuscript submissions: 15 October 2025 | Viewed by 80
Special Issue Editors
Interests: neuroscience; synapse; neural plasticity; cognition
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The regulation of synapses in the brain is a crucial area of research that underpins our understanding of various neurophysiological processes and neurological disorders. Synaptic plasticity, the ability of synapses to strengthen or weaken over time, is fundamental to learning, memory, and overall brain function. Dysregulation of synaptic mechanisms is implicated in numerous conditions, including neurodevelopmental disorders, schizophrenia, and neurodegenerative diseases.
This Special Issue emphasizes the importance of investigating synaptic regulation and its implications for brain health and disease. Recent advances in molecular and cellular techniques have shed light on the intricate processes that govern synaptic formation, maintenance, and elimination. Additionally, emerging evidence highlights the role of the surrounding glial cells and the extracellular matrix in modulating synaptic dynamics.
We invite contributions that explore various aspects of synaptic regulation, including, but not limited to, the following:
- Molecular mechanisms of synaptic formation and maturation.
- The role of synaptic plasticity in learning and memory.
- Contributions of glial cells in synaptic modulation and support.
- Impact of neuroinflammatory processes on synaptic integrity.
- Implications of synaptic dysfunction in psychiatric disorders.
- Novel therapeutic strategies targeting synaptic regulation in brain diseases.
By gathering diverse perspectives on these topics, we aim to enhance our understanding of synaptic regulation's role in brain function and its implications for therapeutic interventions.
We look forward to your valuable contributions.
Prof. Dr. Kunwei Wu
Dr. Guohao Wang
Guest Editors
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- synaptic plasticity
- neurodevelopmental disorders
- glial cells
- synaptic formation
- learning and memory
- neuroinflammation
- neurodegenerative diseases
- extracellular matrix
- synaptic dysfunction
- therapeutic interventions
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