Iron Metabolism in Cells
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Cellular Biochemistry".
Deadline for manuscript submissions: 31 August 2026
Special Issue Editors
Interests: iron metabolism; ferritinophagy; ferritin; ferroptosis; tumor
Interests: iron metabolism; hepcidin regulation; heparan sulfate; heparin; ferroptosis; tumor
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Iron is an essential micronutrient for various biological processes, but it can be toxic when participating in the Fenton reaction and thus contributing to the production of reactive oxygen species (ROS). It is important to maintain cellular iron homeostasis by regulating its uptake, storage, utilization, and exportation. Alterations to any iron-related pathway may lead to iron dysregulation, depletion, or overload, associated with disorders such as anemia or hemochromatosis. Iron can also contribute to tumorigenesis, and ‘iron addiction’ is a well-described phenomenon in cancer cells. Recently, other diseases, such as neurodegenerative disorders, have been linked to altered iron metabolism and the occurrence of iron-dependent cell death, ferroptosis. Overall, growing interest in iron’s involvement in biological and pathological processes has led to new directions in in vitro studies, allowing us to better understand the molecular basis behind these processes.
We are pleased to invite you to contribute to this Special Issue of Biomolecules, titled ‘Iron Metabolism in Cells’. This Special Issue aims to provide an overview of recent research on cellular iron metabolism, including biological processes such as iron transport and utilization and their regulation in physiological and pathological conditions, along with potential therapeutic applications.
For this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) biochemistry, molecular biology, pharmacology, cell biology, and molecular medicine.
We look forward to receiving your contributions.
Dr. Magdalena Gryzik
Dr. Michela Asperti
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- iron metabolism
- iron-related proteins
- iron uptake
- iron storage
- mitochondrial iron metabolism
- iron sensing mechanism
- ferroptosis
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