Spotlight on Hot Cancer Biological Biomarkers

Dear Colleagues,

The identification and characterization of cancer biomarkers represent a cornerstone of modern precision medicine. Initially rooted in molecular biology and pathology—exemplified by advances in liquid biopsy techniques—biomarkers are now extending their impact far beyond traditional laboratory settings. In recent years, the concept of biomarkers has rapidly expanded to encompass imaging biomarkers, functional parameters, and integrative diagnostic tools, fostering a multidisciplinary approach that bridges molecular profiling, radiology, and clinical decision making. This evolution reflects a growing understanding that robust, reliable biomarkers are essential not only for early detection and prognostication but also for therapy selection, monitoring, and outcome prediction.

As the field moves toward increasingly personalized therapeutic strategies, the development and validation of novel cancer biomarkers—across biological, radiological, and computational domains—are of the utmost importance. This Special Issue, “Spotlight on Hot Cancer Biological Biomarkers”, aims to provide a platform for high-impact contributions that can help advance this rapidly evolving area. Original research articles and systematic reviews focusing on innovative biomarkers, translational approaches, and interdisciplinary methodologies are particularly welcome.

Dr. Dania Cioni
Dr. Salvatore Claudio Fanni
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.