The Role of Extracellular Non-Coding RNAs in Health and Disease

Dear Colleagues,

We are pleased to announce a Special Issue of Biomolecules entitled “The Role of Extracellular Non-Coding RNAs in Health and Disease.” Extracellular non-coding RNAs (ncRNAs), including microRNAs, long non-coding RNAs, and circular RNAs, have emerged as critical mediators of intercellular communication and powerful biomarkers for diagnosis, prognosis, and therapeutic monitoring. Their presence in biofluids and extracellular vesicles highlights their unique potential as minimally invasive tools for understanding disease mechanisms and advancing precision medicine. This Special Issue aims to bring together cutting-edge research and comprehensive reviews exploring the molecular biology, functional roles, and clinical applications of extracellular ncRNAs across a wide spectrum of human health and disease contexts. We invite contributions that expand our knowledge of extracellular RNA biology, from fundamental mechanistic insights to translational advances in biomarker discovery and therapeutic development.

Both original research articles and reviews are welcome. We look forward to receiving your contributions.

Prof. Dr. Arijit Mukhopadhyay
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Publisher’s Notice

The Special Issue has been shifted from Section Molecular Genetics to Section Molecular Biomarkers on 4 November 2025. At the time of the move, there were no publications in this Special Issue.